Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart

Cheyenne C S Tseng; Steven Wenker; Maarten H Bakker; Adriaan O Kraaijeveld; Patricia Y W Dankers; Peter R Seevinck; Jouke Smink; Scott Kimmel; Frebus J van Slochteren; Steven A J Chamuleau

doi:10.4244/EIJ-D-17-01081

Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart

Cheyenne C S Tseng, Steven Wenker, Maarten H Bakker, Adriaan O Kraaijeveld, Patricia Y W Dankers, Peter R Seevinck, Jouke Smink, Scott Kimmel, Frebus J van Slochteren, Steven A J Chamuleau

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.

Original language	English
Pages (from-to)	e336-e339
Journal	EuroIntervention
Volume	15
Issue number	4
Early online date	7 Aug 2018
DOIs	https://doi.org/10.4244/EIJ-D-17-01081
Publication status	Published - Jul 2019

Keywords

Animals
Catheters
Feasibility Studies
Heart
Injections
Magnetic Resonance Imaging
Swine

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10.4244/EIJ-D-17-01081

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Tseng, C. C. S., Wenker, S., Bakker, M. H., Kraaijeveld, A. O., Dankers, P. Y. W., Seevinck, P. R., Smink, J., Kimmel, S., van Slochteren, F. J., & Chamuleau, S. A. J. (2019). Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart. EuroIntervention, 15(4), e336-e339. https://doi.org/10.4244/EIJ-D-17-01081

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title = "Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart",

abstract = "The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.",

keywords = "Animals, Catheters, Feasibility Studies, Heart, Injections, Magnetic Resonance Imaging, Swine",

author = "Tseng, \{Cheyenne C S\} and Steven Wenker and Bakker, \{Maarten H\} and Kraaijeveld, \{Adriaan O\} and Dankers, \{Patricia Y W\} and Seevinck, \{Peter R\} and Jouke Smink and Scott Kimmel and \{van Slochteren\}, \{Frebus J\} and Chamuleau, \{Steven A J\}",

year = "2019",

month = jul,

doi = "10.4244/EIJ-D-17-01081",

language = "English",

volume = "15",

pages = "e336--e339",

journal = "EuroIntervention",

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publisher = "Europa Group",

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Tseng, CCS, Wenker, S, Bakker, MH, Kraaijeveld, AO, Dankers, PYW, Seevinck, PR, Smink, J, Kimmel, S, van Slochteren, FJ & Chamuleau, SAJ 2019, 'Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart', EuroIntervention, vol. 15, no. 4, pp. e336-e339. https://doi.org/10.4244/EIJ-D-17-01081

TY - JOUR

T1 - Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance

T2 - feasibility in the porcine heart

AU - Tseng, Cheyenne C S

AU - Wenker, Steven

AU - Bakker, Maarten H

AU - Kraaijeveld, Adriaan O

AU - Dankers, Patricia Y W

AU - Seevinck, Peter R

AU - Smink, Jouke

AU - Kimmel, Scott

AU - van Slochteren, Frebus J

AU - Chamuleau, Steven A J

PY - 2019/7

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N2 - The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.

AB - The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.

KW - Animals

KW - Catheters

KW - Feasibility Studies

KW - Heart

KW - Injections

KW - Magnetic Resonance Imaging

KW - Swine

U2 - 10.4244/EIJ-D-17-01081

DO - 10.4244/EIJ-D-17-01081

M3 - Article

C2 - 30082260

SN - 1774-024X

VL - 15

SP - e336-e339

JO - EuroIntervention

JF - EuroIntervention

IS - 4

ER -

Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart

Abstract

Keywords

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