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Accuracy of routine laboratory tests to predict mortality and deterioration to severe or critical COVID-19 in people with SARS-CoV-2

  • Jan Y. Verbakel*
  • , Liselore De Rop
  • , Inge Stegeman
  • , Gea A. Holtman
  • , Eleanor A. Ochodo
  • , Bada Yang
  • , Fatuma Guleid
  • , Clare Davenport
  • , Jonathan J. Deeks
  • , Jacqueline Dinnes
  • , Sabine Dittrich
  • , Devy Emperador
  • , Lotty Hooft
  • , René Spijker
  • , Ann Van den Bruel
  • , Junfeng Wang
  • , Yemisi Takwoingi
  • , Miranda W. Langendam
  • , Mariska M.G. Leeflang
  • ,
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objectives: This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows:. To assess the accuracy of routine blood-based laboratory tests to predict mortality and deterioration to severe or critical (from mild or moderate) COVID-19 in people with SARS-CoV-2 infection. Secondary objectives Where data are available, we will investigate whether prognostic accuracy varies according to a specific measurement or test, reference standard, timing of outcome verification, sample type, study design, and setting, including prevalence of the target condition (either by stratified analysis or meta-regression).

Original languageEnglish
Article numberCD015050
JournalCochrane Database of Systematic Reviews
Volume2021
Issue number9
DOIs
Publication statusPublished - 17 Sept 2021

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