Abnormally high failure rate for femoral angioplasty in patients with pseudoxanthoma elasticum

Myriam Ammi; Guido Kranenburg; Loukman Omarjee; Ludovic Martin; Wilko Spiering; Georges Lefthériotis

doi:10.1016/j.jvsc.2015.10.001

Abnormally high failure rate for femoral angioplasty in patients with pseudoxanthoma elasticum

Myriam Ammi, Guido Kranenburg, Loukman Omarjee, Ludovic Martin, Wilko Spiering, Georges Lefthériotis^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Pseudoxanthoma elasticum (PXE) is an inherited disease characterized by skin lesions, central blindness, and progressive peripheral occlusive disease. Severe claudication is a frequent symptom for which angioplasty represents a possible therapeutic avenue. We report the outcomes of four patients with PXE treated by angioplasty and stenting of the superficial femoral artery in two centers. These patients exhibited an abnormal failure rate for angioplasty and stenting of the superficial femoral artery, suggesting an as yet unknown susceptibility in such patients. In the absence of further evidence, we do not recommend arterial angioplasty with stenting as a primary surgical approach in PXE patients with femoral artery lesions.

Original language	English
Pages (from-to)	276-278
Number of pages	3
Journal	Journal of Vascular Surgery Cases
Volume	1
Issue number	4
DOIs	https://doi.org/10.1016/j.jvsc.2015.10.001
Publication status	Published - 1 Dec 2015

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10.1016/j.jvsc.2015.10.001

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title = "Abnormally high failure rate for femoral angioplasty in patients with pseudoxanthoma elasticum",

abstract = "Pseudoxanthoma elasticum (PXE) is an inherited disease characterized by skin lesions, central blindness, and progressive peripheral occlusive disease. Severe claudication is a frequent symptom for which angioplasty represents a possible therapeutic avenue. We report the outcomes of four patients with PXE treated by angioplasty and stenting of the superficial femoral artery in two centers. These patients exhibited an abnormal failure rate for angioplasty and stenting of the superficial femoral artery, suggesting an as yet unknown susceptibility in such patients. In the absence of further evidence, we do not recommend arterial angioplasty with stenting as a primary surgical approach in PXE patients with femoral artery lesions.",

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AU - Ammi, Myriam

AU - Kranenburg, Guido

AU - Omarjee, Loukman

AU - Martin, Ludovic

AU - Spiering, Wilko

AU - Lefthériotis, Georges

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Pseudoxanthoma elasticum (PXE) is an inherited disease characterized by skin lesions, central blindness, and progressive peripheral occlusive disease. Severe claudication is a frequent symptom for which angioplasty represents a possible therapeutic avenue. We report the outcomes of four patients with PXE treated by angioplasty and stenting of the superficial femoral artery in two centers. These patients exhibited an abnormal failure rate for angioplasty and stenting of the superficial femoral artery, suggesting an as yet unknown susceptibility in such patients. In the absence of further evidence, we do not recommend arterial angioplasty with stenting as a primary surgical approach in PXE patients with femoral artery lesions.

AB - Pseudoxanthoma elasticum (PXE) is an inherited disease characterized by skin lesions, central blindness, and progressive peripheral occlusive disease. Severe claudication is a frequent symptom for which angioplasty represents a possible therapeutic avenue. We report the outcomes of four patients with PXE treated by angioplasty and stenting of the superficial femoral artery in two centers. These patients exhibited an abnormal failure rate for angioplasty and stenting of the superficial femoral artery, suggesting an as yet unknown susceptibility in such patients. In the absence of further evidence, we do not recommend arterial angioplasty with stenting as a primary surgical approach in PXE patients with femoral artery lesions.

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VL - 1

SP - 276

EP - 278

JO - Journal of Vascular Surgery Cases

JF - Journal of Vascular Surgery Cases

IS - 4

ER -

Abnormally high failure rate for femoral angioplasty in patients with pseudoxanthoma elasticum

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