A therapeutic application of the experience sampling method in the treatment of depression: A randomized controlled trial

Ingrid Kramer, Claudia J P Simons, Jessica A. Hartmann, Claudia Menne-Lothmann, Wolfgang Viechtbauer, Frenk Peeters, Koen Schruers, Alex L. Van Bemmel, M. Inez, Philippe Delespaul, Jim Van Os, Marieke Wichers

    Research output: Contribution to journalArticleAcademicpeer-review

    72 Citations (Scopus)

    Abstract

    In depression, the ability to experience daily life positive affect predicts recovery and reduces relapse rates. Interventions based on the experience sampling method (ESM-I) are ideally suited to provide insight in personal, contextualized patterns of positive affect. The aim of this study was to examine whether add-on ESM-derived feedback on personalized patterns of positive affect is feasible and useful to patients, and results in a reduction of depressive symptomatology. Depressed outpatients (n=102) receiving pharmacological treatment participated in a randomized controlled trial with three arms: an experimental group receiving add-on ESM-derived feedback, a pseudo-experimental group participating in ESM but receiving no feedback, and a control group. The experimental group participated in an ESM procedure (three days per week over a 6-week period) using a palmtop. This group received weekly standardized feedback on personalized patterns of positive affect. Hamilton Depression Rating Scale - 17 (HDRS) and Inventory of Depressive Symptoms (IDS) scores were obtained before and after the intervention. During a 6-month follow-up period, five HDRS and IDS assessments were completed. Add-on ESM-derived feedback resulted in a significant and clinically relevant stronger decrease in HDRS score relative to the control group (p<0.01; -5.5 point reduction in HDRS at 6 months). Compared to the pseudo-experimental group, a clinically relevant decrease in HDRS score was apparent at 6 months (B=-3.6, p=0.053). Self-reported depressive complaints (IDS) yielded the same pattern over time. The use of ESM-I was deemed acceptable and the provided feedback easy to understand. Patients attempted to apply suggestions from ESM-derived feedback to daily life. These data suggest that the efficacy of traditional passive pharmacological approach to treatment of major depression can be enhanced by using person-tailored daily life information regarding positive affect.

    Original languageEnglish
    Pages (from-to)68-77
    Number of pages10
    JournalWorld Psychiatry
    Volume13
    Issue number1
    DOIs
    Publication statusPublished - 1 Feb 2014

    Keywords

    • depressive disorder
    • Ecological momentary assessment
    • experience sampling method
    • intervention study
    • positive affect
    • psychological feedback

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