A Poorest-First Approach to RSV Vaccine Development

Natalie Mazur

doi:10.33540/1504

A Poorest-First Approach to RSV Vaccine Development

Natalie Mazur

Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

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Abstract

The principle aim of this thesis was to use a multidisciplinary approach to establish the foundations for an RSV vaccine in lower and lower-middle income countries (LMICs). Four different approaches were used:
(1) Global epidemiology: to understand the age distribution for life-threatening RSV
(2) Translational medicine: to understand protection through mucosal antibody transfer
(3) Clinical development: to provide an overview of the RSV vaccine pipeline
(4) Ethics: to analyze the ethical framework of post-trial access for RSV vaccine trials

Original language	English
Awarding Institution	University Medical Center (UMC) Utrecht
Supervisors/Advisors	Bont, Louis, Primary supervisor
Award date	12 Sept 2022
Publisher	Utrecht University
Print ISBNs	978-94-6421-835-0
DOIs	https://doi.org/10.33540/1504
Publication status	Published - 12 Sept 2022

Keywords

RSV
vaccines
post-trial access
vaccine development
global health
translational medicine

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natalie mazur phd thesis - 631ad7c75ffeeFinal published version, 20.1 MB

https://dspace.library.uu.nl/handle/1874/422576

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abstract = "The principle aim of this thesis was to use a multidisciplinary approach to establish the foundations for an RSV vaccine in lower and lower-middle income countries (LMICs). Four different approaches were used: (1) Global epidemiology: to understand the age distribution for life-threatening RSV (2) Translational medicine: to understand protection through mucosal antibody transfer (3) Clinical development: to provide an overview of the RSV vaccine pipeline (4) Ethics: to analyze the ethical framework of post-trial access for RSV vaccine trials",

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KW - RSV

KW - vaccines

KW - post-trial access

KW - vaccine development

KW - global health

KW - translational medicine

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A Poorest-First Approach to RSV Vaccine Development

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Keywords

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