A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation

Adriana Augurio; Paolo Cortelletti; Riccardo Tognato; Anne Rios; Riccardo Levato; Jos Malda; Mauro Alini; David Eglin; Gabriele Giancane; Adolfo Speghini; Tiziano Serra

doi:10.1002/aisy.201900105

A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation

Adriana Augurio, Paolo Cortelletti, Riccardo Tognato, Anne Rios, Riccardo Levato, Jos Malda, Mauro Alini, David Eglin, Gabriele Giancane, Adolfo Speghini, Tiziano Serra

Regenerative Medicine and Stem Cells

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Herein, the fabrication of multi-responsive and hierarchically organized nanomaterial using core-shell SrF2 upconverting nanoparticles, doped with Yb3+, Tm3+, Nd3+ incorporated into gelatin methacryloyl matrix, is reported. Upon 800 nm excitation, deep monitoring of 3D-printed constructs is demonstrated. Addition of magnetic self-assembly of iron oxide nanoparticles within the hydrogel provides anisotropic structuration from the nano- to the macro-scale and magnetic responsiveness permitting remote manipulation. The present study provides a new strategy for the fabrication of a novel highly organized multi-responsive material using additive manufacturing, which can have important implications in biomedicine.

Original language	English
Article number	1900105
Number of pages	8
Journal	Advanced Intelligent Systems
Volume	2
Issue number	3
DOIs	https://doi.org/10.1002/aisy.201900105
Publication status	Published - Mar 2020

Keywords

deep tracking
multifunctional
multiscale
remote control
upconversion

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title = "A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation",

abstract = "Herein, the fabrication of multi-responsive and hierarchically organized nanomaterial using core-shell SrF2 upconverting nanoparticles, doped with Yb3+, Tm3+, Nd3+ incorporated into gelatin methacryloyl matrix, is reported. Upon 800 nm excitation, deep monitoring of 3D-printed constructs is demonstrated. Addition of magnetic self-assembly of iron oxide nanoparticles within the hydrogel provides anisotropic structuration from the nano- to the macro-scale and magnetic responsiveness permitting remote manipulation. The present study provides a new strategy for the fabrication of a novel highly organized multi-responsive material using additive manufacturing, which can have important implications in biomedicine.",

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T1 - A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation

AU - Augurio, Adriana

AU - Cortelletti, Paolo

AU - Tognato, Riccardo

AU - Rios, Anne

AU - Levato, Riccardo

AU - Malda, Jos

AU - Alini, Mauro

AU - Eglin, David

AU - Giancane, Gabriele

AU - Speghini, Adolfo

AU - Serra, Tiziano

PY - 2020/3

Y1 - 2020/3

N2 - Herein, the fabrication of multi-responsive and hierarchically organized nanomaterial using core-shell SrF2 upconverting nanoparticles, doped with Yb3+, Tm3+, Nd3+ incorporated into gelatin methacryloyl matrix, is reported. Upon 800 nm excitation, deep monitoring of 3D-printed constructs is demonstrated. Addition of magnetic self-assembly of iron oxide nanoparticles within the hydrogel provides anisotropic structuration from the nano- to the macro-scale and magnetic responsiveness permitting remote manipulation. The present study provides a new strategy for the fabrication of a novel highly organized multi-responsive material using additive manufacturing, which can have important implications in biomedicine.

AB - Herein, the fabrication of multi-responsive and hierarchically organized nanomaterial using core-shell SrF2 upconverting nanoparticles, doped with Yb3+, Tm3+, Nd3+ incorporated into gelatin methacryloyl matrix, is reported. Upon 800 nm excitation, deep monitoring of 3D-printed constructs is demonstrated. Addition of magnetic self-assembly of iron oxide nanoparticles within the hydrogel provides anisotropic structuration from the nano- to the macro-scale and magnetic responsiveness permitting remote manipulation. The present study provides a new strategy for the fabrication of a novel highly organized multi-responsive material using additive manufacturing, which can have important implications in biomedicine.

KW - deep tracking

KW - multifunctional

KW - multiscale

KW - remote control

KW - upconversion

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DO - 10.1002/aisy.201900105

M3 - Article

SN - 2640-4567

VL - 2

JO - Advanced Intelligent Systems

JF - Advanced Intelligent Systems

IS - 3

M1 - 1900105

ER -

A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation

Abstract

Keywords

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