A helical PTFE arteriovenous access graft to swirl flow across the distal anastomosis: results of a preliminary clinical study.

H.J.T.A.M. Huijbregts; P.J. Blankestijn; C.G. Caro; N.J. Cheshire; M.T. Hoedt; R.P. Tutein Nolthenius; F.L. Moll

A helical PTFE arteriovenous access graft to swirl flow across the distal anastomosis: results of a preliminary clinical study.

Translated title of the contribution: A helical PTFE arteriovenous access graft to swirl flow across the distal anastomosis: results of a preliminary clinical study.

H.J.T.A.M. Huijbregts, P.J. Blankestijn, C.G. Caro, N.J. Cheshire, M.T. Hoedt, R.P. Tutein Nolthenius, F.L. Moll

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Intimal hyperplasia develops preferentially in regions where the blood flow is stagnant and wall shear stress low. The small amplitude helical geometry of the SwirlGraft was designed to ensure physiological-type swirling flow, and thus suppress the triggers. We report the first conceptual testing of the SwirlGraft. Primary, assisted primary and secondary patency rates at 6 months in 20 patients were 57.9+/-11.4%, 84.4+/-8.3% and 100+/-0.0%. There was angiographic evidence of reduction of helical geometry in a proportion of the grafts. The helical graft is associated with high assisted primary and secondary patency. Elaboration of the surgical implantation techniques and an improved SwirlGraft design can be expected to exploit the advantages of the helical concept.

Translated title of the contribution	A helical PTFE arteriovenous access graft to swirl flow across the distal anastomosis: results of a preliminary clinical study.
Original language	Undefined/Unknown
Pages (from-to)	472-475
Number of pages	4
Journal	European Journal of Vascular and Endovascular Surgery
Volume	33
Issue number	4
Publication status	Published - 2007

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title = "A helical PTFE arteriovenous access graft to swirl flow across the distal anastomosis: results of a preliminary clinical study.",

abstract = "Intimal hyperplasia develops preferentially in regions where the blood flow is stagnant and wall shear stress low. The small amplitude helical geometry of the SwirlGraft was designed to ensure physiological-type swirling flow, and thus suppress the triggers. We report the first conceptual testing of the SwirlGraft. Primary, assisted primary and secondary patency rates at 6 months in 20 patients were 57.9+/-11.4%, 84.4+/-8.3% and 100+/-0.0%. There was angiographic evidence of reduction of helical geometry in a proportion of the grafts. The helical graft is associated with high assisted primary and secondary patency. Elaboration of the surgical implantation techniques and an improved SwirlGraft design can be expected to exploit the advantages of the helical concept.",

author = "H.J.T.A.M. Huijbregts and P.J. Blankestijn and C.G. Caro and N.J. Cheshire and M.T. Hoedt and {Tutein Nolthenius}, R.P. and F.L. Moll",

year = "2007",

language = "Undefined/Unknown",

volume = "33",

pages = "472--475",

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T1 - A helical PTFE arteriovenous access graft to swirl flow across the distal anastomosis: results of a preliminary clinical study.

AU - Huijbregts, H.J.T.A.M.

AU - Blankestijn, P.J.

AU - Caro, C.G.

AU - Cheshire, N.J.

AU - Hoedt, M.T.

AU - Tutein Nolthenius, R.P.

AU - Moll, F.L.

PY - 2007

Y1 - 2007

N2 - Intimal hyperplasia develops preferentially in regions where the blood flow is stagnant and wall shear stress low. The small amplitude helical geometry of the SwirlGraft was designed to ensure physiological-type swirling flow, and thus suppress the triggers. We report the first conceptual testing of the SwirlGraft. Primary, assisted primary and secondary patency rates at 6 months in 20 patients were 57.9+/-11.4%, 84.4+/-8.3% and 100+/-0.0%. There was angiographic evidence of reduction of helical geometry in a proportion of the grafts. The helical graft is associated with high assisted primary and secondary patency. Elaboration of the surgical implantation techniques and an improved SwirlGraft design can be expected to exploit the advantages of the helical concept.

AB - Intimal hyperplasia develops preferentially in regions where the blood flow is stagnant and wall shear stress low. The small amplitude helical geometry of the SwirlGraft was designed to ensure physiological-type swirling flow, and thus suppress the triggers. We report the first conceptual testing of the SwirlGraft. Primary, assisted primary and secondary patency rates at 6 months in 20 patients were 57.9+/-11.4%, 84.4+/-8.3% and 100+/-0.0%. There was angiographic evidence of reduction of helical geometry in a proportion of the grafts. The helical graft is associated with high assisted primary and secondary patency. Elaboration of the surgical implantation techniques and an improved SwirlGraft design can be expected to exploit the advantages of the helical concept.

M3 - Article

SN - 1078-5884

VL - 33

SP - 472

EP - 475

JO - European Journal of Vascular and Endovascular Surgery

JF - European Journal of Vascular and Endovascular Surgery

IS - 4

ER -

A helical PTFE arteriovenous access graft to swirl flow across the distal anastomosis: results of a preliminary clinical study.

Abstract

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