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A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics

  • Laurens T van der Meer
  • , Esmé Waanders
  • , Marloes Levers
  • , Hanka Venselaar
  • , Debbie Roeleveld
  • , Joachim Boos
  • , Claudia Lanvers
  • , Roger J Brüggemann
  • , Roland P Kuiper
  • , Peter M Hoogerbrugge
  • , Frank N van Leeuwen*
  • , D Maroeska te Loo
  • *Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Original languageEnglish
Pages (from-to)3027-9
Number of pages3
JournalBlood
Volume124
Issue number19
DOIs
Publication statusPublished - 6 Nov 2014
Externally publishedYes

Keywords

  • Antineoplastic Agents/pharmacokinetics
  • Asparaginase/pharmacokinetics
  • Cathepsin B/genetics
  • Child
  • Drug Monitoring/methods
  • Female
  • Germ-Line Mutation
  • Humans
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy

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