TY - JOUR
T1 - A critical approach to the clinical use of deformable image registration software. In response to Meijneke et al.
AU - van Rijssel, Michael J.
AU - Dahele, Max
AU - Verbakel, Wilko F. A. R.
AU - Rosario, Tezontl S.
PY - 2014/9
Y1 - 2014/9
N2 - We congratulate Meijneke et al. on their publication describing their experience with thoracic re-irradiation [1] where they emphasized the use of non-rigid registration (deformable image registration, DIR) for dose deformation and accumulation. Although they provided references in support of their DIR algorithm, we note that these do not specifically demonstrate the accuracy of their DIR algorithm and subsequent dose accumulation in the lung. Commercial DIR software packages are now widely available and while developments in DIR are welcome, methods to allow clinical users to evaluate the uncertainty associated with its use in various situations have not kept pace with its diffusion into clinical practice.
AB - We congratulate Meijneke et al. on their publication describing their experience with thoracic re-irradiation [1] where they emphasized the use of non-rigid registration (deformable image registration, DIR) for dose deformation and accumulation. Although they provided references in support of their DIR algorithm, we note that these do not specifically demonstrate the accuracy of their DIR algorithm and subsequent dose accumulation in the lung. Commercial DIR software packages are now widely available and while developments in DIR are welcome, methods to allow clinical users to evaluate the uncertainty associated with its use in various situations have not kept pace with its diffusion into clinical practice.
KW - STEREOTACTIC RADIOTHERAPY
KW - LUNG-CANCER
KW - VALIDATION
U2 - 10.1016/j.radonc.2014.01.029
DO - 10.1016/j.radonc.2014.01.029
M3 - Comment/Letter to the editor
C2 - 24631145
SN - 0167-8140
VL - 112
SP - 447
EP - 448
JO - Radiotherapy & Oncology
JF - Radiotherapy & Oncology
IS - 3
ER -