7 tesla T2-weighted MRI as a tool to improve detection of focal cortical dysplasia

Tim J. Veersema*, Pieter van Eijsden, PH Gosselaar, J Hendrikse, Jaco J M Zwanenburg, Wim G M Spliet, Eleonora Aronica, Kees P J Braun, Cyrille H. Ferrier

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Focal cortical dysplasia is one of the most common underlying pathologies in patients who undergo surgery for refractory epilepsy. Absence of a MRI-visible lesion necessitates additional diagnostic tests and is a predictor of poor surgical outcome.We describe a series of six patients with refractory epilepsy due to histopathologically-confirmed focal cortical dysplasia, for whom pre-surgical 7 tesla T2-weighted MRIwas acquired. In four of six patients, T2 sequences showed areas of marked superficial hypointensity, co-localizing with the epileptogenic lesion. 7 tesla T2 hypointensities overlying focal cortical dysplasia may represent leptomeningeal venous vascular abnormalities associated with the underlying dysplastic cortex. Adding T2 sequences to the MRI protocol may aid in the detection of focal cortical dysplasias.

Original languageEnglish
Pages (from-to)315-323
Number of pages9
JournalEpileptic Disorders
Issue number3
Publication statusPublished - 1 Sept 2016


  • Cortical localization
  • Epilepsy
  • FCD
  • Magnetic resonance imaging
  • Susceptibility weighted
  • Ultra-high field


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