TY - JOUR
T1 - ΔAPACHE II for predicting course and outcome of nosocomial Staphylococcus aureus bacteremia and its relation to host defense
AU - Yzerman, Ed P.F.
AU - Boelens, Hélène A.M.
AU - Tjhie, Jeroen H.T.
AU - Kluytmans, Jan A.J.W.
AU - Mouton, Johan W.
AU - Verbrugh, Henri A.
PY - 1996
Y1 - 1996
N2 - To predict at an early phase the clinical course and outcome of nosocomial Staphylococcus aureus bacteremia, the APACHE II score at onset of bacteremia was calculated in 99 patients. A ΔAPACHE II score (i.e., the difference between this score and one calculated for the day before the bacteremia) was also determined. This ΔAPACHE II score was highly significantly correlated with clinical course (P < .001) and outcome (P < .001). The risk of a complicated clinical course and of dying from S. aureus bacteremia is determined at the very onset of bacteremia, and this risk can best be assessed by calculating the ΔAPACHE II score. Furthermore, a positive correlation was found between ΔAPACHE II scores and the level of serum opsonic activity (P < .003) toward S. aureus. Therefore, the complicated clinical course of S. aureus bacteremia is not due to a relative lack of specific opsonins.
AB - To predict at an early phase the clinical course and outcome of nosocomial Staphylococcus aureus bacteremia, the APACHE II score at onset of bacteremia was calculated in 99 patients. A ΔAPACHE II score (i.e., the difference between this score and one calculated for the day before the bacteremia) was also determined. This ΔAPACHE II score was highly significantly correlated with clinical course (P < .001) and outcome (P < .001). The risk of a complicated clinical course and of dying from S. aureus bacteremia is determined at the very onset of bacteremia, and this risk can best be assessed by calculating the ΔAPACHE II score. Furthermore, a positive correlation was found between ΔAPACHE II scores and the level of serum opsonic activity (P < .003) toward S. aureus. Therefore, the complicated clinical course of S. aureus bacteremia is not due to a relative lack of specific opsonins.
UR - https://www.scopus.com/pages/publications/0029934486
U2 - 10.1093/infdis/173.4.914
DO - 10.1093/infdis/173.4.914
M3 - Article
C2 - 8603971
AN - SCOPUS:0029934486
SN - 0022-1899
VL - 173
SP - 914
EP - 919
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 4
ER -