Editor’s choice 2018 Cardiovascular Research (most read manuscripts): Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Sluijter JPG, Davidson SM, Boulanger CM, Iren Buzás E, de Kleijn DPV, Engel FB, Giricz Z, Hausenloy DJ, Kishore R, Lecour S, Leor J, Madonna R, Perrino C, Prunier F, Sahoo S, Schiffelers RM, Schulz R, Van Laake LW, Ytrehus K, Ferdinandy P. Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology