Wiepke Cahn

2024

Accelerated Cortical Thinning in Schizophrenia is Associated With Rare and Common Predisposing Variation to Schizophrenia and Neurodevelopmental Disorders

1 Sept 2024, In: Biological Psychiatry. 96, 5, p. 376-389 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Author Correction: Transmural collaborative care model for the review of antipsychotics: a feasibility study of a complex intervention (Scientific Reports, (2024), 14, 1, (12367), 10.1038/s41598-024-62349-9)

Jakobs, K. M., van den Brule‑Barnhoorn, K. J., van Lieshout, J., Janzing, J. G. E., Cahn, W., van den Muijsenbergh, M., Biermans, M. C. J. & Bischoff, E. W. M. A., 2024, In: Scientific Reports. 14, 1, 18659.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

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Childhood abuse v. neglect and risk for major psychiatric disorders

Alkema, A., Marchi, M., Van Der Zaag, J. A. J., Van Der Sluis, D., Warrier, V., Ophoff, R. A., Kahn, R. S., Cahn, W., Hovens, J. G. F. M., Riese, H., Scheepers, F., Penninx, B. W. J. H., Cecil, C., Oldehinkel, A. J., Vinkers, C. H., Boks, M. P. M., Jun 2024, In: Psychological medicine. 54, 8, p. 1598-1609 12 p.

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Correction: Electroconvulsive Therapy Versus Aripiprazole Addition to Clozapine in Patients with Clozapine-Resistant Symptoms (EMECLO): A Protocol of a Single-Blind, Multicenter, Randomized-Controlled Feasibility Trial

den Toom, M., Blanken, L., Horn, I., Veerman, S., van der Vlugt-Molenaar, J. J. B., de Koning, M. B., Bogers, J., Enterman, J., de Jonge, M., Cianci, D., Frederix, G. W. J., de Haas, H. J., Storosum, B. W., Veereschild, M., Javadzadeh, M., Schulte, P. F. J., Cohen, D., van Os, J., Cahn, W. & de Haan, L. & 2 others, Zantvoord, J. B. & Luykx, J. J., Nov 2024, In: Pharmacopsychiatry. 57, 6, p. e1 1 p.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

COVID in een ‘psychiatrisch verpleeghuis’: een exploratief onderzoek

Translated title of the contribution: COVID in a 'psychiatric nursing home': An exploratory researchvan Wulfften Palthe, J. E., Joling, K. J., Wouters, F., Everaerd, D. S., Schellekens, A., Zinkstok, J., Cahn, W., Tendolkar, I., Visser, D., Cath, D. C., Straathof, S. & Kok, R. M., 2024, In: Tijdschrift voor Psychiatrie. 66, 7, p. 348-353 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

DeltaScan for the Assessment of Acute Encephalopathy and Delirium in ICU and non-ICU Patients, a Prospective Cross-Sectional Multicenter Validation Study

Ditzel, F. L., Hut, S. C. A., van den Boogaard, M., Boonstra, M., Leijten, F. S. S., Wils, E.-J., van Nesselrooij, T., Kromkamp, M., Rood, P. J. T., Röder, C., Bouvy, P. F., Coesmans, M., Osse, R. J., Pop-Purceleanu, M., van Dellen, E., Krulder, J. W. M., Milisen, K., Faaij, R., Vondeling, A. M. & Kamper, A. M. & 12 others, van Munster, B. C., de Jonghe, A., Winters, M. A. M., van der Ploeg, J., van der Zwaag, S., Koek, D. H. L., Drenth-van Maanen, C. A. C., Beishuizen, A., van den Bos, D. M., Cahn, W., Schuit, E. & Slooter, A. J. C., Sept 2024, In: The American Journal of Geriatric Psychiatry. 32, 9, p. 1093-1104 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

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Distinct genetic liability profiles define clinically relevant patient strata across common diseases

Cahn, W., Ophoff, R. A., 1 Jul 2024, In: Nature Communications. 15, 1, 28 p., 5534.

Research output: Contribution to journal › Article › Academic › peer-review

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Electroconvulsive Therapy Versus Aripiprazole Addition to Clozapine in Patients with Clozapine-Resistant Symptoms (EMECLO): A Protocol of a Single-Blind, Multicenter, Randomized-Controlled Feasibility Trial

den Toom, M., Blanken, L., Horn, I., Veerman, S., van der Vlugt-Molenaar, J. J. B., de Koning, M. B., Bogers, J., Enterman, J., de Jonge, M., Cianci, D., Frederix, G. W. J., de Haas, H., Storosum, B. W., Veereschild, M., Javadzadeh, M., Schulte, P. F. J., Cohen, D., van Os, J., Cahn, W. & de Haan, L. & 2 others, Zantvoord, J. B. & Luykx, J. J., Nov 2024, In: Pharmacopsychiatry. 57, 6, p. 290-295 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Forward head posture associated with reduced cardiorespiratory fitness in psychotic disorders compared to autism spectrum disorder and healthy controls

van de Meent, I., Koomen, L., de Boer, R., Le Clercq, L., Janssen, D., Boute, M., Maat, A., van Dellen, E. & Cahn, W., 26 Jul 2024, In: Scientific Reports. 14, 1, 17143.

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Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

García-Marín, L. M., Campos, A. I., Diaz-Torres, S., Rabinowitz, J. A., Ceja, Z., Mitchell, B. L., Grasby, K. L., Thorp, J. G., Agartz, I., Alhusaini, S., Ames, D., Amouyel, P., Andreassen, O. A., Arfanakis, K., Arias-Vasquez, A., Armstrong, N. J., Athanasiu, L., Bastin, M. E., Beiser, A. S. & Bennett, D. A. & 170 others, Bis, J. C., Boks, M. P. M., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Buitelaar, J. K., Burkhardt, R., Cahn, W., Calhoun, V. D., Carmichael, O. T., Chakravarty, M., Chen, Q., Ching, C. R. K., Cichon, S., Crespo-Facorro, B., Crivello, F., Dale, A. M., Smith, G. D., de Geus, E. J. C., De Jager, P. L., de Zubicaray, G. I., Debette, S., DeCarli, C., Depondt, C., Desrivières, S., Djurovic, S., Ehrlich, S., Erk, S., Espeseth, T., Fernández, G., Filippi, I., Fisher, S. E., Fleischman, D. A., Fletcher, E., Fornage, M., Forstner, A. J., Francks, C., Franke, B., Ge, T., Goldman, A. L., Grabe, H. J., Green, R. C., Grimm, O., Groenewold, N. A., Gruber, O., Gudnason, V., Håberg, A. K., Haukvik, U. K., Heinz, A., Hibar, D. P., Hilal, S., Himali, J. J., Ho, B. C., Hoehn, D. F., Hoekstra, P. J., Hofer, E., Hoffmann, W., Holmes, A. J., Homuth, G., Hosten, N., Ikram, M. K., Ipser, J. C., Jack, C. R., Jahanshad, N., Jönsson, E. G., Kahn, R. S., Kanai, R., Klein, M., Knol, M. J., Launer, L. J., Lawrie, S. M., Hellard, S. L., Lee, P. H., Lemaître, H., Li, S., Liewald, D. C. M., Lin, H., Longstreth, W. T., Lopez, O. L., Luciano, M., Maillard, P., Marquand, A. F., Martin, N. G., Martinot, J. L., Mather, K. A., Mattay, V. S., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mirza-Schreiber, N., Milaneschi, Y., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Maniega, S. M., Nauck, M., Nho, K., Niessen, W. J., Nöthen, M. M., Nyquist, P. A., Oosterlaan, J., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Psaty, B. M., Pütz, B., Reppermund, S., Rietschel, M. D., Risacher, S. L., Romanczuk-Seiferth, N., Romero-Garcia, R., Roshchupkin, G. V., Rotter, J. I., Sachdev, P. S., Sämann, P. G., Saremi, A., Sargurupremraj, M., Saykin, A. J., Schmaal, L., Schmidt, H., Schmidt, R., Schofield, P. R., Scholz, M., Schumann, G., Schwarz, E., Shen, L., Shin, J., Sisodiya, S. M., Smith, A. V., Smoller, J. W., Soininen, H. S., Steen, V. M., Stein, D. J., Stein, J. L., Thomopoulos, S. I., Toga, A. W., Tordesillas-Gutiérrez, D., Trollor, J. N., Valdes-Hernandez, M. C., van ′t Ent, D., van Bokhoven, H., van der Meer, D., van der Wee, N. J. A., Vázquez-Bourgon, J., Veltman, D. J., Vernooij, M. W., Villringer, A., Vinke, L. N., Völzke, H., Walter, H., Wardlaw, J. M., Weinberger, D. R., Weiner, M. W., Wen, W., Westlye, L. T., Westman, E., White, T., Witte, A. V., Wolf, C., Yang, J., Zwiers, M. P., Ikram, M. A., Seshadri, S., Thompson, P. M., Satizabal, C. L., Medland, S. E. & Rentería, M. E., Nov 2024, In: Nature genetics. 56, 11, p. 2333-2344 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

García-Marín, L. M., Campos, A. I., Diaz-Torres, S., Rabinowitz, J. A., Ceja, Z., Mitchell, B. L., Grasby, K. L., Thorp, J. G., Agartz, I., Alhusaini, S., Ames, D., Amouyel, P., Andreassen, O. A., Arfanakis, K., Vasquez, A. A., Armstrong, N. J., Athanasiu, L., Bastin, M. E., Beiser, A. S. & Bennett, D. A. & 31 others, Bis, J. C., Boks, M. P., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Buitelaar, J. K., Burkhardt, R., Cahn, W., Calhoun, V. D., Carmichael, O. T., Chakravarty, M., Chen, Q., Ching, C. R. K., Cichon, S., Crespo-Facorro, B., Crivello, F., Dale, A. M., Smith, G. D., de Geus, E. J., De Jager, P. L., de Zubicaray, G. I., Debette, S., DeCarli, C., Depondt, C., Desrivières, S., Ikram, M. K., Kahn, R. S., Klein, M., Shen, L., Weinberger, D. R., 15 Aug 2024, medRxiv, (medRxiv).

Research output: Working paper › Preprint › Academic

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'I am proud of how I handled it'. Exploring the impact of the COVID-19 pandemic and related restrictions on well-being of adults with severe mental illness using qualitative methods

van Rijn, L., Metz, M. J., van der Velden, P. R., Mathijsen, P., Swildens, W. E., Schellekens, A. F. A., Cahn, W., Milota, M. M. & Zinkstok, J. R., Feb 2024, In: Health Expectations. 27, 1, 14 p., e13983.

Research output: Contribution to journal › Article › Academic › peer-review

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Leefstijl bij jongvolwassenen met en zonder psychotische stoornis

Translated title of the contribution: Lifestyle in young adults with and without a psychotic disorderSwildens, W., Kranenburg, J., Van Ens, W., Van Rijswijk, D. & Cahn, W., 2024, In: Tijdschrift voor Psychiatrie. 66, 2, p. 76-83 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume

1 Apr 2024, In: International Journal of Clinical and Health Psychology. 24, 2, 12 p., 100458.

Research output: Contribution to journal › Article › Academic › peer-review

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Moving from supported to independent living: what are the barriers and facilitators for individuals with psychosis?

Poppe, A., Tiles-Sar, N., Konings, S. R. A., Habtewold, T. D., Bruggeman, R., Alizadeh, B. Z., van der Meer, L., Jul 2024, In: Social Psychiatry and Psychiatric Epidemiology. 59, 7, p. 1243-1254 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Muva physical activity intervention improves social functioning in people with a severe mental illness: A pragmatic stepped wedge cluster controlled trial

Maria Koomen, L. E., Theodora van de Meent, I. H., Deenik, J., van Dellen, E., Schnack, H. G., Hendrikus van Werkhoven, C., Swildens, W. E., van Meijel, B., Staal, W., Jörg, F., Scheepers, F. & Cahn, W., Mar 2024, In: Mental Health and Physical Activity. 26, 100601.

Research output: Contribution to journal › Article › Academic › peer-review

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Response to psychotic experiences: Impact of personality traits on perceived levels of distress

May 2024, In: Schizophrenia Research. 267, p. 282-290 9 p.

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Structural brain abnormalities and aggressive behaviour in schizophrenia: Mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium

5 Feb 2024, medRxiv, 20 p.

Research output: Working paper › Preprint › Academic

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The Role of Childhood Trauma in Affective Stress Recovery in Early Psychosis: An Experience Sampling Study

Ader, L., Schick, A., Vaessen, T., Morgan, C., Kempton, M. J., Valmaggia, L., McGuire, P., Myin-Germeys, I., Lafit, G., Reininghaus, U., Cahn, W., van Os, J., 1 Jul 2024, In: Schizophrenia bulletin. 50, 4, p. 891-902 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

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Transmural collaborative care model for the review of antipsychotics: a feasibility study of a complex intervention

Jakobs, K. M., van den Brule-Barnhoorn, K. J., van Lieshout, J., Janzing, J. G. E., Cahn, W., van den Muijsenbergh, M., Biermans, M. C. J. & Bischoff, E. W. M. A., 29 May 2024, In: Scientific Reports. 14, 1, 12367.

Research output: Contribution to journal › Article › Academic › peer-review

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2023

Age-Related Social Cognitive Performance in Individuals With Psychotic Disorders and Their First-Degree Relatives

29 Nov 2023, In: Schizophrenia bulletin. 49, 6, p. 1460-1469 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Associations between genetic liabilities to smoking behavior and schizophrenia symptoms in patients with a psychotic disorder, their siblings and healthy controls

May 2023, In: Psychiatry Research. 323, p. 1-8 115143.

Research output: Contribution to journal › Article › Academic › peer-review

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fMRI connectivity as a biomarker of antipsychotic treatment response: A systematic review

Dominicus, L. S., van Rijn, L., van der A, J., van der Spek, R., Podzimek, D., Begemann, M., de Haan, L., van der Pluijm, M., Otte, W. M., Cahn, W., Röder, C. H., Schnack, H. G. & van Dellen, E., Jan 2023, In: NeuroImage: Clinical. 40, p. 1-18 18 p., 103515.

Research output: Contribution to journal › Review article › peer-review

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GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors

1 Oct 2023, In: American Journal of Psychiatry. 180, 10, p. 723-738 16 p.

Research output: Contribution to journal › Article › Academic › peer-review

Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium

4 Apr 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2213880120.

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Personal recovery suits us all: A study in patients with non-affective psychosis, unaffected siblings and healthy controls

Van Eck, R. M., van Velden, J., Vellinga, A., van der Krieke, L., Castelein, S., de Haan, L., Schirmbeck, F., van Amelsvoort, T., Bartels-Velthuis, A. A., Bruggeman, R., Cahn, W., Simons, C. J. P. & van Os, J., May 2023, In: Schizophrenia Research. 255, p. 24-32 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

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Pharmacogenetics and phenoconversion: the influence on side effects experienced by psychiatric patients

den Uil, M. G., Hut, H. W., Wagelaar, K. R., Abdullah-Koolmees, H., Cahn, W., Wilting, I. & Deneer, V. H. M., 25 Aug 2023, In: Frontiers in Genetics. 14, p. 1-14 1249164.

Research output: Contribution to journal › Article › Academic › peer-review

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Prevalence and predictors of inappropriate prescribing in outpatients with severe mental illness

Koomen, L., van de Meent, I., Elferink, F., Wilting, I. & Cahn, W., 1 Jan 2023, In: Therapeutic advances in psychopharmacology. 13, p. 1-12

Research output: Contribution to journal › Article › Academic › peer-review

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Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis

1 Nov 2023, In: Schizophrenia bulletin. 49, 6, p. 1625-1636 12 p.

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Revealing the impact of psychiatric comorbidities on treatment outcome in early psychosis using counterfactual model explanation

van Dee, V., Kia, S. M., Winter-van Rossum, I., Kahn, R. S., Cahn, W. & Schnack, H. G., 12 Oct 2023, In: Frontiers in Psychiatry. 14, 11 p., 1237490.

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Risk factors for violent behaviour before and after the onset of schizophrenia spectrum disorder: A naturalistic case-control study in the Netherlands

Dec 2023, In: Schizophrenia Research. 262, p. 1-7 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

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Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

9 Aug 2023, In: Cell genomics. 3, 8, 100356.

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Screening and prevalence of cardiometabolic risk factors in patients with severe mental illness: A multicenter cross-sectional cohort study in the Netherlands

Noortman, L., de Winter, L., van Voorst, A., Cahn, W. & Deenik, J., Oct 2023, In: Comprehensive Psychiatry. 126, 152406.

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Systematic review and meta-analysis on predictors of prognosis in patients with schizophrenia spectrum disorders: An overview of current evidence and a call for prospective research and open access to datasets

van Dee, V., Schnack, H. G. & Cahn, W., Apr 2023, In: Schizophrenia Research. 254, p. 133-142 10 p.

Research output: Contribution to journal › Review article › peer-review

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The association between mental healthcare professionals' personal characteristics and their clinical lifestyle practices: A national cross-sectional study in the Netherlands

Koomen, L. E. M., Deenik, J. & Cahn, W., 4 Dec 2023, In: European Psychiatry. 66, 1, p. 1-7 7 p., e96.

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The impact of schizophrenia spectrum disorder, bipolar disorder and borderline personality disorder on radiotherapy treatment and overall survival in cancer patients: A matched pair analysis

Peters, M., Boersma, H. W., van Rossum, P. S. N., van Oort, J., Cahn, W. & Verhoeff, J. J. C., May 2023, In: Clinical and translational radiation oncology. 40, 7 p., 100618.

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The Laban/Bartenieff Movement System in gait-analysis reveals upper-lower body movement dysconnectivity in psychotic disorders

van de Meent, I., Maat, A., Boute, M., van Dellen, E. & Cahn, W., Jun 2023, In: Schizophrenia Research. 256, p. 47-49 3 p.

Research output: Contribution to journal › Letter › Academic › peer-review

The short and long-term effects of a lifestyle intervention in children with mental illnesses: a randomized controlled trial (Movementss study)

van Tetering, E. M. A., Muskens, J. B., Deenik, J., Pillen, S., Cahn, W., von Rosenstiel, I., Oomen, M., Rommelse, N. N., Staal, W. G. & Klip, H., 21 Jul 2023, In: BMC Psychiatry. 23, 1, 529.

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Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia

19 May 2023, In: iScience. 26, 5, 106701.

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2022

Antipsychotic-induced weight gain: Is the weight over? New guidelines needed

de Boer, N. & Cahn, W., Sept 2022, In: Acta Psychiatrica Scandinavica. 146, 3, p. 185-189 5 p.

Research output: Contribution to journal › Editorial › Academic › peer-review

Cardiorespiratory fitness and self-reported physical activity levels of referring mental healthcare professionals, and their attitudes and referral practices related to exercise and physical health

Deenik, J., Koomen, L. E. M., Scheewe, T. W., van Deursen, F. P. & Cahn, W., Oct 2022, In: Journal of Psychiatric Research. 154, p. 19-27 9 p.

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Comparing psychotic experiences in low-and-middle-income-countries and high-income-countries with a focus on measurement invariance

Jaya, E. S., Wüsten, C., Alizadeh, B. Z., van Amelsvoort, T., Bartels-Velthuis, A. A., van Beveren, N. J., Bruggeman, R., Cahn, W., de Haan, L., Delespaul, P., Luykx, J. J., Myin-Germeys, I., Kahn, R. S., Schirmbeck, F., Simons, C. J. P., van Haren, N. E., van Os, J., van Winkel, R., Fonseca-Pedrero, E. & Peters, E. & 4 others, Verdoux, H., Woodward, T. S., Ziermans, T. B. & Lincoln, T. M., Jun 2022, In: Psychological medicine. 52, 8, p. 1509-1516 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Deprescriptie van psychofarmaca; praktijk en behoeften van patiënten en naasten

Translated title of the contribution: Tapering of psychotropic drugs: current practice and needs of patients and their relativesKoomen, L. E. M., de Boer, J. N., van den Eijnden, M. J. M., Vos de Wael, N. M. A. M., Berg, N., Wilting, I. & Cahn, W., 2022, In: Tijdschrift voor Psychiatrie. 64, 7, p. 424-430 7 p.

Research output: Contribution to journal › Article › Professional

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

1 Feb 2022, In: Biological Psychiatry. 91, 3, p. 313-327 15 p.

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Effectiveness and implementation of a multidisciplinary lifestyle focused approach in the treatment of inpatients with mental illness (MULTI +): a stepped wedge study protocol

den Bleijker, N. M., van Schothorst, M. M. E., Hendriksen, I. J. M., Cahn, W., de Vries, N. K., van Harten, P. N. & Deenik, J., 31 Mar 2022, In: BMC Psychiatry. 22, 1, p. 1-11 230.

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