Research output per year
Research output per year
Personal profile
Personal webpage
nl.linkedin.com/pub/stefan-nierkens/16/89/912/en
Nierkens Group - Prinses Máxima Centrum - Research (prinsesmaximacentrum.nl)
Biography
Dr. Stefan Nierkens (PhD) is Associate Professor and Medical Immunologist, accredited according to guidelines of the College of Medical Immunologists of the Dutch Society of Immunology, in the UMC Utrecht and Princess Máxima Center for Pediatric Oncology. Within the ISO15189-accredited laboratory his focus areas are Hemato-oncology, Immune monitoring, Cell and functional diagnostics, and Serology.
Dr. Nierkens is Associate Professor Pediatric Tumor Immunology and HCT and focusses on the development of innovative immunotherapy treatment strategies (based on dendritic cells and gene-engineered T cells) to improve the outcome of pediatric cancers (e.g. acute leukemia and neuroblastoma). Furthermore, his lab (12 fte) focuses on the combination of advanced immune monitoring and PK-PD modeling to provide predictable immune reconstitution after hematopoietic cell transplantation.
Fellowship & awards
KWF fellowship
Kika
ZonMW-TAS
VillaJoep
Ammodo
Side activities
Advisory Board / Consultancy / Speaker: Sobi, Medimmune, GamidaCell, Olink
External positions
Medische Immunologie - Overeenkomstige taken als Medisch Immunoloog bij LTI UMCU - Prinses Maxima Centrum voor Kinderoncologie
23 Aug 2018 → 31 Dec 3999
commissie - expertise medische immunologie - NVVI
1 Jan 2018 → 31 Dec 3999
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Engineering anti-BCMA CAR T cells for enhancing myeloma killing efficacy via apoptosis regulation
Kimman, T., Cuenca, M., Tieland, R. G., Rockx-Brouwer, D., Janssen, J., Motais, B., Slomp, A., Pleijte, C., Heijhuurs, S., Meringa, A. D., Boschloo, W., Bosma, D. M., Kroos, S., Lo Presti, V., Sluijter, J. P. G., Nierkens, S., Bovenschen, N., Kuball, J., van Mil, A. & Minnema, M. C. & 2 others, , 19 May 2025, In: Nature Communications. 16, 1, 12 p., 4638.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Ex vivo T-lymphopoiesis assays assisting corrective treatment choice for genetically undefined T-lymphocytopaenia
Golwala, Z. M., Goncalves, H. S., Moirangthem, R. D., Evans, G., Lizot, S., de Koning, C., Garrigue, A., Corredera, M. M., Ocampo-Godinez, J. M., Howley, E., Kricke, S., Awuah, A., Obiri-Yeboa, I., Rai, R., Sebire, N., Bernard, F., De Braem, V. B. C., Boztug, K., Cole, T. & Gennery, A. R. & 24 others, , May 2025, In: Clinical Immunology. 274, 13 p., 110453.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Increased Clonal Hematopoiesis in Long-term Survivors of Pediatric Hematopoietic Cell Transplantation
Müskens, K. F., Wieringa, N., van Bergen, M. G. J. M., Bense, J. E., Te Pas, B. M., de Pagter, A. P. J., Lankester, A. C., Bierings, M. B., Neuberg, D. S., Haitjema, S., Kremer, L. C. M., Huls, G. A., Nierkens, S., Jansen, J. H., Lindemans, C. A., de Graaf, A. O. & Belderbos, M. E., 4 Mar 2025, In: Blood cancer discovery. 6, 2, p. 110-118 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Multicenter validation of secondary hemophagocytic lymphohistiocytosis diagnostic criteria
Lachmann, G., Heeren, P., Schuster, F. S., Nyvlt, P., Spies, C., Feinkohl, I., Schenk, T., Ammouri, W., Debaugnies, F., Galicier, L., Jia, Y., Meena, N., Nagant, C., Neth, O., Nierkens, S., San Martin, J., Sun, H. W., Wang, Y., Wang, Z. & Yoon, J. H. & 4 others, , Mar 2025, In: Journal of Internal Medicine. 297, 3, p. 312-327 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
The BAMBOO method for correcting batch effects in high throughput proximity extension assays for proteomic studies
Smits, H. M., Delemarre, E. M., Pandit, A., Schoneveld, A. H., Oldenburg, B., van Wijk, F., Nierkens, S. & Drylewicz, J., 9 Jan 2025, In: Scientific Reports. 15, 1, 1 p., 1498.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Downloads (Pure)
Activities
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Immune monitoring for solid tumors
Stefan Nierkens (Speaker)
23 Mar 2023 → 24 Mar 2023Activity: Talk or presentation › Invited talk › Academic
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Measureable residual disease in AML & Post-transplantation therapies
Stefan Nierkens (Speaker)
14 Mar 2023 → 15 Mar 2023Activity: Talk or presentation › Oral presentation › Academic
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Make CAR-T cells feel at home
Stefan Nierkens (Speaker)
27 Feb 2023Activity: Talk or presentation › Invited talk › Academic
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Immune Monitoring in pediatric BCP-ALL patients treated with CAR-T therapy
Stefan Nierkens (Speaker)
21 Nov 2022Activity: Talk or presentation › Invited talk › Professional
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The use of liquid biopsy approaches in immunology
Stefan Nierkens (Speaker)
11 Oct 2022Activity: Talk or presentation › Invited talk › Academic
Prizes
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Joos Kerckhaert Award
Nierkens, Stefan (Recipient), 5 Oct 2023
Prize: Prize (including medals and awards)
Press/Media
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Burgemeester op bezoek voor gezamenlijk project WKZ-PMC - Connect
Boelens, J.-J., van Noesel, M. & Nierkens, S.
23/05/16
1 Media contribution
Press/Media: Public Engagement Activities
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Immunologie onderzoek versnellen en verbeteren’
7/12/12
1 Media contribution
Press/Media: Public Engagement Activities