Research output per year
Research output per year
Personal profile
Biography
Sam van Beuningen is an Assistant Professor and leads a research team in AI and Automation for Cellular Disease models within the Department of Cellular Disease Models (UMC Utrecht) and the Regenerative Medicine Center Utrecht. He has an educational background in molecular biology and holds a PhD in cell biology from Utrecht University. During his PhD project, he gained extensive experience in various molecular biology and advanced microscopy techniques at the Department of Cell Biology (Utrecht University). After obtaining his PhD, Sam continued his career as a Data Science consultant for various large Dutch enterprises. Here he developed various data and machine-learning solutions to improve business processes. Since 2021 he is working within the Centre for Living Technologies where he combines his molecular biology and microscopy knowledge with his data science experience. Sam and his team run the Cellular Screening Technologies facility and the AI lab for Living Technologies where they develop automated lab and AI pipelines for the screening and analysis of patient derived technologies.
Research interests
- AI in image analysis
- Advanced microscopy
- Lab automation
- High-troughput cellular screening
- Cellular Disease Models
External positions
Visiting Lecturer (Gastdocent) - Teaching AI for Microscopy masterclass (one day a year) - HAN University of Applied Sciences
1 Dec 2025 → 31 Dec 3999
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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OrgaSegment: deep-learning based organoid segmentation to quantify CFTR dependent fluid secretion
Lefferts, J. W., Kroes, S., Smith, M. B., Niemöller, P. J., Nieuwenhuijze, N. D. A., Sonneveld van Kooten, H. N., van der Ent, C. K., Beekman, J. M. & van Beuningen, S. F. B., 13 Mar 2024, In: Communications biology. 7, 1, 9 p., 319.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Downloads (Pure) -
CFTR Function Restoration upon Elexacaftor/Tezacaftor/Ivacaftor Treatment in Patient-Derived Intestinal Organoids with Rare CFTR Genotypes.
Lefferts, J. W., Bierlaagh, M. C., Kroes, S., Nieuwenhuijze, N. D. A., Sonneveld van Kooten, H. N., Niemöller, P. J., Verburg, T. F., Janssens, H. M., Muilwijk, D., van Beuningen, S. F. B., van der Ent, C. K. & Beekman, J. M., Oct 2023, In: International Journal of Molecular Sciences. 24, 19, 14 p., 14539.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure) -
Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids
Rodenburg, L. W., Delpiano, L., Railean, V., Centeio, R., Pinto, M. C., Smits, S. M. A., van der Windt, I. S., van Hugten, C. F. J., van Beuningen, S. F. B., Rodenburg, R. N. P., van der Ent, C. K., Amaral, M. D., Kunzelmann, K., Gray, M. A., Beekman, J. M. & Amatngalim, G. D., 21 Oct 2022, In: International Journal of Molecular Sciences. 23, 20, 12657.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Downloads (Pure) -
Trim46 organizes microtubule fasciculation in the axon initial segment
Harterink, M., Vocking, K., Pan, X., Soriano Jerez, E. M., Slenders, L., Fréal, A., Tas, R. P., Van De Wetering, W. J., Timmer, K., Motshagen, J., Van Beuningen, S. F. B., Kapitein, L. C., Geerts, W. J. C., Post, J. A. & Hoogenraad, C. C., 19 Jun 2019, In: Journal of Neuroscience. 39, 25, p. 4864-4873 10 p.Research output: Contribution to journal › Article › Academic › peer-review
18 Citations (Scopus) -
Antibodies to TRIM46 are associated with paraneoplastic neurological syndromes
van Coevorden-Hameete, M. H., van Beuningen, S. F. B., Perrenoud, M., Will, L. M., Hulsenboom, E., Demonet, J. F., Sabater, L., Kros, J. M., Verschuuren, J. J. G. M., Titulaer, M. J., de Graaff, E., Sillevis Smitt, P. A. E. & Hoogenraad, C. C., Sept 2017, In: Annals of Clinical and Translational Neurology. 4, 9, p. 680-686 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access13 Citations (Scopus)