René Kahn

2018

A state-independent network of depressive, negative and positive symptoms in male patients with schizophrenia spectrum disorders

van Rooijen, G., Isvoranu, A. M., Kruijt, O. H., van Borkulo, C. D., Meijer, C., Wigman, J. T. W., Ruhé, H. G., de Haan, L., Bruggeman, R., Cahn, W., de Haan, L., Kahn, R. S., Meijer, C., Myin-Germeys, I., van Os, J., Bartels-Velthuis, A. A., Genetic Risk and OUtcome of Psychosis investigators & GROUP Investigators, 1 Mar 2018, In: Schizophrenia Research. 193, p. 232-239 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

At-risk individuals display altered brain activity following stress

van Leeuwen, J. M. C., Vink, M., Fernández, G., Hermans, E. J., Joëls, M., Kahn, R. S. & Vinkers, C. H., 1 Aug 2018, In: Neuropsychopharmacology. 43, 9, p. 1954-1960 7 p.

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Clozapine as a first- or second-line treatment in schizophrenia: a systematic review and meta-analysis

Okhuijsen-Pfeifer, C., Huijsman, E. A. H., Hasan, A., Sommer, I. E. C., Leucht, S., Kahn, R. S. & Luykx, J. J., 1 Oct 2018, In: Acta Psychiatrica Scandinavica. 138, 4, p. 281-288 8 p.

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1 Citation (Scopus)

Comprehensive pathway analyses of schizophrenia risk loci point to dysfunctional postsynaptic signaling

Schijven, D., Kofink, D., Tragante, V., Verkerke, M., Pulit, S. L., Kahn, R. S., Veldink, J. H., Vinkers, C. H., Boks, M. P. & Luykx, J. J., 1 Sept 2018, In: Schizophrenia Research. 199, p. 195-202 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium

van Erp, T. G. M., Walton, E., Hibar, D. P., Schmaal, L., Jiang, W., Glahn, D. C., Pearlson, G. D., Yao, N., Fukunaga, M., Hashimoto, R., Okada, N., Yamamori, H., Bustillo, J. R., Clark, V. P., Agartz, I., Mueller, B. A., Cahn, W., de Zwarte, S. M. C., Hulshoff Pol, H. E. & Kahn, R. S. & 31 others, Ophoff, R. A., van Haren, N. E. M., Andreassen, O. A., Dale, A. M., Doan, N. T., Gurholt, T. P., Hartberg, C. B., Haukvik, U. K., Jørgensen, K. N., Lagerberg, T. V., Melle, I., Westlye, L. T., Gruber, O., Kraemer, B., Richter, A., Zilles, D., Calhoun, V. D., Crespo-Facorro, B., Roiz-Santiañez, R., Tordesillas-Gutiérrez, D., Loughland, C., Carr, V. J., Catts, S., Cropley, V. L., Fullerton, J. M., Green, M. J., Seal, M., Lim, K. O., Koops, S., Sommer, I. E. C. & Karolinska Schizophrenia Project, 1 Nov 2018, In: Biological Psychiatry. 84, 9, p. 644-654 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Cortical magnetization transfer abnormalities and connectome dysconnectivity in schizophrenia

Wei, Y., Collin, G., Mandl, R. C. W., Cahn, W., Keunen, K., Schmidt, R., Kahn, R. S. & van den Heuvel, M. P., 1 Feb 2018, In: Schizophrenia Research. 192, p. 172-178 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Detailed T1-Weighted Profiles from the Human Cortex Measured in Vivo at 3 Tesla MRI

Ferguson, B., Petridou, N., Fracasso, A., van Den Heuvel, M. P., Brouwer, R. M., Hulshoff Pol, H. E., Kahn, R. S. & Mandl, R. C. W., Apr 2018, In: Neuroinformatics. 16, 2, p. 181-196 16 p.

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Double hits in schizophrenia

1 Aug 2018, In: Human Molecular Genetics. 27, 15, p. 2755-2761 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

Ni, G., Moser, G., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A. & Begemann, M. & 35 others, Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Kahn, R. S., Van Os, J., Strengman, E., Ophoff, R. A., Psychosis Endophenotypes International Consortium, Wellcome Trust Case Control Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Psychosis Endophenotypes International Consortium & Wellcome Trust Case Control Consortium, 7 Jun 2018, In: American Journal of Human Genetics. 102, 6, p. 1185-1194 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

Genetic vulnerability to DUSP22 promoter hypermethylation is involved in the relation between in utero famine exposure and schizophrenia

Boks, M. P., Houtepen, L. C., Xu, Z., He, Y., Ursini, G., Maihofer, A. X., Rajarajan, P., Yu, Q., Xu, H., Wu, Y., Wang, S., Shi, J. P., Hulshoff Pol, H. E., Strengman, E., Rutten, B. P. F., Jaffe, A. E., Kleinman, J. E., Baker, D. G., Hol, E. M. & Akbarian, S. & 6 others, Nievergelt, C. M., De Witte, L. D., Vinkers, C. H., Weinberger, D. R., Yu, J. & Kahn, R. S., 21 Aug 2018, In: npj Schizophrenia. 4, 1, 16.

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Genome-wide association meta-analysis of age at first cannabis use

Minică, C. C., Verweij, K. J. H., van der Most, P. J., Mbarek, H., Bernard, M., van Eijk, K. R., Lind, P. A., Liu, M. Z., Maciejewski, D. F., Palviainen, T., Sánchez-Mora, C., Sherva, R., Taylor, M., Walters, R. K., Abdellaoui, A., Bigdeli, T. B., Branje, S. J. T., Brown, S. A., Casas, M. & Corley, R. P. & 50 others, Davey-Smith, G., Davies, G. E., Ehli, E. A., Farrer, L., Fedko, I. O., Garcia-Martínez, I., Gordon, S. D., Hartman, C. A., Heath, A. C., Hickie, I. B., Hickman, M., Hopfer, C. J., Hottenga, J. J., Kahn, R. S., Kaprio, J., Korhonen, T., Kranzler, H. R., Krauter, K., van Lier, P. A. C., Madden, P. A. F., Medland, S. E., Neale, M. C., Meeus, W. H. J., Montgomery, G. W., Nolte, I. M., Oldehinkel, A. J., Pausova, Z., Ramos-Quiroga, J. A., Richarte, V., Rose, R. J., Shin, J., Stallings, M. C., Wall, T. L., Ware, J. J., Wright, M. J., Zhao, H., Koot, H. M., Paus, T., Hewitt, J. K., Ribasés, M., Loukola, A., Boks, M. P., Snieder, H., Munafò, M. R., Gelernter, J., Boomsma, D. I., Martin, N. G., Gillespie, N. A., Vink, J. M. & Derks, E. M., Nov 2018, In: Addiction. 113, 11, p. 2073-2086 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Ruderfer, D. M., Ripke, S., McQuillin, A., Boocock, J., Stahl, E. A., Pavlides, J. M. W., Mullins, N., Charney, A. W., Ori, A. P. S., Loohuis, L. M. O., Domenici, E., Di Florio, A., Papiol, S., Kalman, J. L., Trubetskoy, V., Adolfsson, R., Agartz, I., Agerbo, E., Akil, H. & Albani, D. & 35 others, Albus, M., Alda, M., Alexander, M., Alliey-Rodriguez, N., Als, T. D., Amin, F., Anjorin, A., Arranz, M. J., Awasthi, S., Bacanu, S. A., Badner, J. A., Baekvad-Hansen, M., Bakker, S., Band, G., Barchas, J. D., Barroso, I., Bass, N., Bauer, M., Baune, B. T., Begemann, M., Bellenguez, C., Belliveau, R. A., Bellivier, F., Bender, S., Boks, M., Cahn, W., Kahn, R. S., Van Os, J., Strengman, E., Ophoff, R. A., Psychosis Endophenotypes International Consortium, Wellcome Trust Case Control Consortium, Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium [email protected], Psychosis Endophenotypes International Consortium & Wellcome Trust Case Control Consortium, 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journal › Article › Academic › peer-review

Glucocorticoid receptor exon 1_F methylation and the cortisol stress response in health and disease

Schür, R. R., van Leeuwen, J. M. C., Houtepen, L. C., Joëls, M., Kahn, R. S., Boks, M. P. & Vinkers, C. H., 1 Nov 2018, In: Psychoneuroendocrinology. 97, p. 182-189 8 p.

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Impaired self-agency inferences in schizophrenia: The role of cognitive capacity and causal reasoning style

Prikken, M., van der Weiden, A., Kahn, R. S., Aarts, H. & van Haren, N. E. M., 1 Jan 2018, In: European Psychiatry. 47, p. 27-34 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Improving genetic prediction by leveraging genetic correlations among human diseases and traits

Maier, R. M., Zhu, Z., Lee, S. H., Trzaskowski, M., Ruderfer, D. M., Stahl, E. A., Ripke, S., Wray, N. R., Yang, J., Visscher, P. M., Robinson, M. R., Forstner, A. J., Mcquillin, A., Trubetskoy, V., Wang, W., Wang, Y., Coleman, J. R. I., Gaspar, H. A., De Leeuw, C. A. & Whitehead Pavlides, J. M. & 221 others, Olde Loohuis, L. M., Pers, T. H., Lee, P. H., Charney, A. W., Dobbyn, A. L., Huckins, L., Boocock, J., Giambartolomei, C., Roussos, P., Mullins, N., Awasthi, S., Agerbo, E., Als, T. D., Pedersen, C. B., Grove, J., Kupka, R., Regeer, E. J., Anjorin, A., Casas, M., Mahon, P. B., Allardyce, J., Escott-Price, V., Forty, L., Fraser, C., Kogevinas, M., Frank, J., Streit, F., Strohmaier, J., Treutlein, J., Witt, S. H., Kennedy, J. L., Strauss, J. S., Garnham, J., O'donovan, C., Slaney, C., Steinberg, S., Thorgeirsson, T. E., Hautzinger, M., Steffens, M., Perlis, R. H., Sánchez-Mora, C., Hipolito, M., Lawson, W. B., Nwulia, E. A., Levy, S. E., Foroud, T. M., Jamain, S., Young, A. H., Mckay, J. D., Albani, D., Zandi, P., Potash, J. B., Zhang, P., Raymond Depaulo, J., Bergen, S. E., Juréus, A., Karlsson, R., Kandaswamy, R., Mcguffin, P., Rivera, M., Lissowska, J., Cruceanu, C., Lucae, S., Cervantes, P., Budde, M., Gade, K., Heilbronner, U., Pedersen, M. G., Morris, D. W., Weickert, C. S., Weickert, T. W., Macintyre, D. J., Lawrence, J., Elvsåshagen, T., Smeland, O. B., Djurovic, S., Xi, S., Green, E. K., Czerski, P. M., Hauser, J., Xu, W., Vedder, H., Oruc, L., Spijker, A. T., Gordon, S. D., Medland, S. E., Curtis, D., Mühleisen, T. W., Badner, J., Scheftner, W. A., Sigurdsson, E., Schork, N. J., Schatzberg, A. F., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Knowles, J. A., Szelinger, S., Montgomery, G. W., Boks, M., Adolfsson, A. N., Hoffmann, P., Bauer, M., Pfennig, A., Leber, M., Kittel-Schneider, S., Reif, A., Del-Favero, J., Fischer, S. B., Herms, S., Reinbold, C. S., Degenhardt, F., Koller, A. C., Maaser, A., Ori, A., Dale, A. M., Fan, C. C., Greenwood, T. A., Nievergelt, C. M., Shehktman, T., Shilling, P. D., Byerley, W., Bunney, W., Alliey-Rodriguez, N., Clarke, T. K., Liu, C., Coryell, W., Akil, H., Burmeister, M., Flickinger, M., Li, J. Z., Mcinnis, M. G., Meng, F., Thompson, R. C., Watson, S. J., Zollner, S., Guan, W., Green, M. J., Craig, D., Sobell, J. L., Milani, L., Gordon-Smith, K., Knott, S. V., Perry, A., Parra, J. G., Mayoral, F., Rivas, F., Rice, J. P., Barchas, J. D., Børglum, A. D., Mortensen, P. B., Mors, O., Grigoroiu-Serbanescu, M., Bellivier, F., Etain, B., Leboyer, M., Ramos-Quiroga, J. A., Agartz, I., Amin, F., Azevedo, M. H., Bass, N., Black, D. W., Blackwood, D. H. R., Bruggeman, R., Buccola, N. G., Choudhury, K., Cloninger, C. R., Corvin, A., Craddock, N., Daly, M. J., Datta, S., Donohoe, G. J., Duan, J., Dudbridge, F., Fanous, A., Freedman, R., Freimer, N. B., Friedl, M., Gill, M., Gurling, H., De Haan, L., Hamshere, M. L., Hartmann, A. M., Holmans, P. A., Kahn, R. S., Keller, M. C., Kenny, E., Kirov, G. K., Krabbendam, L., Krasucki, R., Lencz, T., Levinson, D. F., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Magnusson, P. K. E., Maier, W., Malhotra, A. K., Mattheisen, M., Mattingsdal, M., Mccarroll, S. A., Medeiros, H., Melle, I., Milanova, V., Myin-Germeys, I., Neale, B. M., Ophoff, R. A., Owen, M. J., Pimm, J., Purcell, S. M., Puri, V., Quested, D. J., Rossin, L., Sanders, A. R., Shi, J., Sklar, P., St Clair, D., Stroup, T. S., Van Os, J., Wiersma, D. & Zammit, S., 1 Dec 2018, In: Nature Communications. 9, 1, 989.

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5 Citations (Scopus)

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Intra- and interobserver agreement for fetal cerebral measurements in 3D-ultrasonography

Albers, M. E. W. A., Buisman, E. T. I. A., Kahn, R. S., Franx, A., Onland-Moret, N. C. & de Heus, R., Aug 2018, In: Human Brain Mapping. 39, 8, p. 3277-3284 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Is going into stable symptomatic remission associated with a more positive development of life satisfaction? A 10-year follow-up study of first episode psychosis

Gardsjord, E. S., Romm, K. L., Røssberg, J. I., Friis, S., Barder, H. E., Evensen, J., Haahr, U., ten Velden Hegelstad, W., Joa, I., Johannessen, J. O., Langeveld, J., Larsen, T. K., Opjordsmoen, S., Rund, B. R., Simonsen, E., Vaglum, P., McGlashan, T. & Melle, I., 1 Mar 2018, In: Schizophrenia Research. 193, p. 364-369 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Long-term cognitive trajectories and heterogeneity in patients with schizophrenia and their unaffected siblings

Islam, M. A., Habtewold, T. D., van Es, F. D., Quee, P. J., van den Heuvel, E. R., Alizadeh, B. Z., Bruggeman, R., Bartels-Velthuis, A. A., van Beveren, N. J., Cahn, W., de Haan, L., Delespaul, P., Meijer, C. J., Myin-Germeys, I., Kahn, R. S., Schirmbeck, F., Simons, C. J. P., van Amelsvoort, T., van Haren, N. E. & van Os, J. & 2 others, van Winkel, R., 1 Dec 2018, In: Acta Psychiatrica Scandinavica. 138, 6, p. 591-604 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Microglia innately develop within cerebral organoids

Ormel, P. R., Vieira de Sá, R., van Bodegraven, E. J., Karst, H., Harschnitz, O., Sneeboer, M. A. M., Johansen, L. E., van Dijk, R. E., Scheefhals, N., Berdenis van Berlekom, A., Ribes Martínez, E., Kling, S., MacGillavry, H. D., van den Berg, L. H., Kahn, R. S., Hol, E. M., de Witte, L. D. & Pasterkamp, R. J., 1 Dec 2018, In: Nature Communications [E]. 9, 1, 4167.

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Molecular pathogenicity of anti-NMDA receptor autoantibody from patients with first-episode psychosis

Jézéquel, J., Lepleux, M., Kahn, R. S., Honnorat, J., Leboyer, M. & Groc, L., 1 Apr 2018, In: American Journal of Psychiatry. 175, 4, p. 382-383 2 p.

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4 Citations (Scopus)

No neuronal autoantibodies detected in plasma of patients with a bipolar I disorder

Snijders, G., Titulaer, M. J., Bergink, V., Bastiaansen, A. E., Schreurs, M. W. J., Ophoff, R. A., Boks, M. P., Kahn, R. S. & de Witte, L. D., 1 Jan 2018, In: Psychiatry Research. 259, p. 460-462 3 p.

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Obsessive–compulsive symptoms and overall psychopathology in psychotic disorders: longitudinal assessment of patients and siblings

Schirmbeck, F., Swets, M., Meijer, C. J., Zink, M., de Haan, L., Kahn, R. S., van Os, J., Bruggeman, R., Cahn, W., Bartels-Velthuis, A. A., Myin-Germeys, I. & GROUP Investigators, 1 Apr 2018, In: European Archives of Psychiatry and Clinical Neuroscience. 268, 3, p. 279-289 11 p.

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2 Citations (Scopus)

Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium

Walton, E., Hibar, D. P., van Erp, T. G. M., Potkin, S. G., Roiz-Santiañez, R., Crespo-Facorro, B., Suarez-Pinilla, P., Van Haren, N. E. M., De Zwarte, S. M. C., Kahn, R. S., Cahn, W., Doan, N. T., Jorgensen, K. N., Gurholt, T. P., Agartz, I., Andreassen, O. A., Westlye, L. T., Melle, I., Berg, A. O. & Morch-Johnsen, L. & 38 others, Færden, A., Flyckt, L., Fatouros-Bergman, H., Jönsson, E. G., Hashimoto, R., Yamamori, H., Fukunaga, M., Jahanshad, N., Rossi, P., Piras, F., Banaj, N., Spalletta, G., Gur, R. E., Gur, R. C., Hanssen-de Wolf, J. E., Satterthwaite, T. D., Beard, L. M., Sommer, I. E., Koops, S., Gruber, O., Richter, A., Krämer, B., Kelly, R. S., Donohoe, G., McDonald, C., Cannon, D. M., Corvin, A. S., Gill, M., Di Giorgio, A., Bertolino, A., Lawrie, S. M., Nickson, T., Whalley, H. C., Neilson, E., Calhoun, V. D., Thompson, P. M., Turner, J. A. & Ehrlich, S., 1 Jan 2018, In: Psychological Medicine. 48, 1, p. 82-94 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L. & Alfred, T. & 380 others, Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Allison, M., Amouyel, P., Asselbergs, F. W., Auer, P. L., Balkau, B., Bang, L. E., Barroso, I., Bastarache, L., Benn, M., Bergmann, S., Bielak, L. F., Blüher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Böger, C. A., Bork-Jensen, J., Bots, M. L., Bottinger, E. P., Bowden, D. W., Brandslund, I., Breen, G., Brilliant, M. H., Broer, L., Brumat, M., Burt, A. A., Butterworth, A. S., Campbell, P. T., Cappellani, S., Carey, D. J., Catamo, E., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Cocca, M., Collins, F. S., Cook, J. P., Corley, J., Corominas Galbany, J., Cox, A. J., Crosslin, D. S., Cuellar-Partida, G., D'Eustacchio, A., Danesh, J., Davies, G., Bakker, P. I. W., Groot, M. C. H., Mutsert, R., Deary, I. J., Dedoussis, G., Demerath, E. W., Heijer, M., Hollander, A. I., Ruijter, H. M., Dennis, J. G., Denny, J. C., Angelantonio, E., Drenos, F., Du, M., Dubé, M. P., Dunning, A. M., Easton, D. F., Edwards, T. L., Ellinghaus, D., Ellinor, P. T., Elliott, P., Evangelou, E., Farmaki, A. E., Farooqi, I. S., Faul, J. D., Fauser, S., Feng, S., Ferrannini, E., Ferrieres, J., Florez, J. C., Ford, I., Fornage, M., Franco, O. H., Franke, A., Franks, P. W., Friedrich, N., Frikke-Schmidt, R., Galesloot, T. E., Gan, W., Gandin, I., Gasparini, P., Gibson, J., Giedraitis, V., Gjesing, A. P., Gordon-Larsen, P., Gorski, M., Grabe, H. J., Grant, S. F. A., Grarup, N., Griffiths, H. L., Grove, M. L., Gudnason, V., Gustafsson, S., Haessler, J., Hakonarson, H., Hammerschlag, A. R., Hansen, T., Harris, K. M., Harris, T. B., Hattersley, A. T., Have, C. T., Hayward, C., He, L., Heard-Costa, N. L., Heath, A. C., Heid, I. M., Helgeland, Ø., Hernesniemi, J., Hewitt, A. W., Holmen, O. L., Hovingh, G. K., Howson, J. M. M., Hu, Y., Huang, P. L., Huffman, J. E., Ikram, M. A., Ingelsson, E., Jackson, A. U., Jansson, J. H., Jarvik, G. P., Jensen, G. B., Jia, Y., Johansson, S., Jørgensen, M. E., Jørgensen, T., Jukema, J. W., Kahali, B., Kahn, R. S., Kähönen, M., Kamstrup, P. R., Kanoni, S., Kaprio, J., Karaleftheri, M., Kardia, S. L. R., Karpe, F., Kathiresan, S., Kee, F., Kiemeney, L. A., Kim, E., Kitajima, H., Komulainen, P., Kooner, J. S., Kooperberg, C., Korhonen, T., Kovacs, P., Kuivaniemi, H., Kutalik, Z., Kuulasmaa, K., Kuusisto, J., Laakso, M., Lakka, T. A., Lamparter, D., Lange, E. M., Lange, L. A., Langenberg, C., Larson, E. B., Lee, N. R., Lehtimäki, T., Lewis, C. E., Li, H., Li, J., Li-Gao, R., Lin, H., Lin, K. H., Lin, L. A., Lin, X., Lind, L., Lindström, J., Linneberg, A., Liu, C. T., Liu, D. J., Liu, Y., Lo, K. S., Lophatananon, A., Lotery, A. J., Loukola, A., Luan, J., Lubitz, S. A., Lyytikäinen, L. P., Männistö, S., Marenne, G., Mazul, A. L., McCarthy, M. I., McKean-Cowdin, R., Medland, S. E., Meidtner, K., Milani, L., Mistry, V., Mitchell, P., Mohlke, K. L., Moilanen, L., Moitry, M., Montgomery, G. W., Mook-Kanamori, D. O., Moore, C., Mori, T. A., Morris, A. D., Morris, A. P., Müller-Nurasyid, M., Munroe, P. B., Nalls, M. A., Narisu, N., Nelson, C. P., Neville, M., Nielsen, S. F., Nikus, K., Njølstad, P. R., Nordestgaard, B. G., Nyholt, D. R., O'Connel, J. R., O'Donoghue, M. L., Olde Loohuis, L. M., Ophoff, R. A., Owen, K. R., Packard, C. J., Padmanabhan, S., Palmer, C. N. A., Palmer, N. D., Pasterkamp, G., Patel, A. P., Pattie, A., Pedersen, O., Peissig, P. L., Peloso, G. M., Pennell, C. E., Perola, M., Perry, J. A., Perry, J. R. B., Pers, T. H., Person, T. N., Peters, A., Petersen, E. R. B., Peyser, P. A., Pirie, A., Polasek, O., Polderman, T. J., Puolijoki, H., Raitakari, O. T., Rasheed, A., Rauramaa, R., Reilly, D. F., Renström, F., Rheinberger, M., Ridker, P. M., Rioux, J. D., Rivas, M. A., Roberts, D. J., Robertson, N. R., Robino, A., Rolandsson, O., Rudan, I., Ruth, K. S., Saleheen, D., Salomaa, V., Samani, N. J., Sapkota, Y., Sattar, N., Schoen, R. E., Schreiner, P. J., Schulze, M. B., Scott, R. A., Segura-Lepe, M. P., Shah, S. H., Sheu, W. H. H., Sim, X., Slater, A. J., Small, K. S., Smith, A. V., Southam, L., Spector, T. D., Speliotes, E. K., Starr, J. M., Stefansson, K., Steinthorsdottir, V., Stirrups, K. E., Strauch, K., Stringham, H. M., Stumvoll, M., Sun, L., Surendran, P., Swift, A. J., Tada, H., Tansey, K. E., Tardif, J. C., Taylor, K. D., Teumer, A., Thompson, D. J., Thorleifsson, G., Thorsteinsdottir, U., Thuesen, B. H., Tönjes, A., Tromp, G., Trompet, S., Tsafantakis, E., Tuomilehto, J., Tybjaerg-Hansen, A., Tyrer, J. P., Uher, R., Uitterlinden, A. G., Uusitupa, M., Laan, S. W., Duijn, C. M., Leeuwen, N., Van Setten, J., Vanhala, M., Varbo, A., Varga, T. V., Varma, R., Velez Edwards, D. R., Vermeulen, S. H., Veronesi, G., Vestergaard, H., Vitart, V., Vogt, T. F., Völker, U., Vuckovic, D., Wagenknecht, L. E., Walker, M., Wallentin, L., Wang, F., Wang, C. A., Wang, S., Wang, Y., Ware, E. B., Wareham, N. J., Warren, H. R., Waterworth, D. M., Wessel, J., White, H. D., Willer, C. J., Wilson, J. G., Witte, D. R., Wood, A. R., Wu, Y., Yaghootkar, H., Yao, J., Yao, P., Yerges-Armstrong, L. M., Young, R., Zeggini, E., Zhan, X., Zhang, W., Zhao, J. H., Zhao, W., Zhou, W., Zondervan, K. T., Rotter, J. I., Pospisilik, J. A., Rivadeneira, F., Borecki, I. B., Deloukas, P., Frayling, T. M., Lettre, G., North, K. E., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F., 1 Jan 2018, In: Nature Genetics. 50, 1, p. 26-41 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Psychotic Experiences and Related Distress: A Cross-national Comparison and Network Analysis Based on 7141 Participants From 13 Countries

Wusten, C., Schlier, B., Jaya, E. S., Alizadeh, B. Z., Bartels-Velthuis, A. A., van Beveren, N. J., Bruggeman, R., Cahn, W., de Haan, L., Delespaul, P., Meijer, C. J., Myin-Germeys, I., Kahn, R. S., Schirmbeck, F., Simons, C. J. P., van Haren, N. E., van Os, J., van Winkel, R., Fonseca-Pedrero, E. & Peters, E. & 4 others, Verdoux, H., Woodward, T. S., Ziermans, T. B. & Lincoln, T. M., 17 Oct 2018, In: Schizophrenia Bulletin. 44, 6, p. 1185-1194 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Response to initial antipsychotic treatment in first episode psychosis is related to anterior cingulate glutamate levels: a multicentre H-1-MRS study (OPTiMiSE): a multicentre ¹H-MRS study (OPTiMiSE)

Egerton, A., Broberg, B. V., van Haren, N., Merritt, K., Barker, G. J., Lythgoe, D. J., Perez-Iglesias, R., Baandrup, L., Düring, S. W., Sendt, K. V., Stone, J. M., Rostrup, E., Sommer, I. E., Glenthøj, B., Kahn, R. S., Dazzan, P. & McGuire, P., Nov 2018, In: Molecular Psychiatry. 23, 11, p. 2145-2155 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Reward-related brain structures are smaller in patients with schizophrenia and comorbid metabolic syndrome

de Nijs, J., Schnack, H. G., Koevoets, M. G. J. C., Kubota, M., Kahn, R. S., van Haren, N. E. M. & Cahn, W., 1 Dec 2018, In: Acta Psychiatrica Scandinavica. 138, 6, p. 581-590 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Sleep Disturbances, Psychosocial Difficulties, and Health Risk Behavior in 16,781 Dutch Adolescents

Verkooijen, S., de Vos, N., Bakker-Camu, B. J. W., Branje, S. J. T., Kahn, R. S., Ophoff, R. A., Plevier, C. M. & Boks, M. P. M., Aug 2018, In: Academic Pediatrics. 18, 6, p. 655-661 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Subjective quality of life in psychosis: Evidence for an association with real world functioning?

Leendertse, P., Myin-Germeys, I., Lataster, T., Simons, C. J. P., Oorschot, M., Lardinois, M., Schneider, M., van Os, J., Reininghaus, U., Alizadeh, B. Z., Bartels-Velthuis, A. A., van Beveren, N. J. M., Bruggeman, R., Cahn, W., de Haan, L., Delespaul, P., Meijer, C. J., Myin-Germeys, I., Kahn, R. S. & Schirmbeck, F. & 3 others, Simons, C. J. P., van Haren, N. E. & van Winkel, R., 1 Mar 2018, In: Psychiatry Research. 261, p. 116-123 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project

Blokland, G. A. M., del Re, E. C., Mesholam-Gately, R. I., Jovicich, J., Trampush, J. W., Keshavan, M. S., DeLisi, L. E., Walters, J. T. R., Turner, J. A., Malhotra, A. K., Lencz, T., Shenton, M. E., Voineskos, A. N., Rujescu, D., Giegling, I., Kahn, R. S., Roffman, J. L., Holt, D. J., Ehrlich, S. & Kikinis, Z. & 54 others, Dazzan, P., Murray, R. M., Di Forti, M., Lee, J., Sim, K., Lam, M., Wolthusen, R. P. F., de Zwarte, S. M. C., Walton, E., Cosgrove, D., Kelly, S., Maleki, N., Osiecki, L., Picchioni, M. M., Bramon, E., Russo, M., David, A. S., Mondelli, V., Reinders, A. A. T. S., Falcone, M. A., Hartmann, A. M., Konte, B., Morris, D. W., Gill, M., Corvin, A. P., Cahn, W., Ho, N. F., Liu, J. J., Keefe, R. S. E., Gollub, R. L., Manoach, D. S., Calhoun, V. D., Schulz, S. C., Sponheim, S. R., Goff, D. C., Buka, S. L., Cherkerzian, S., Thermenos, H. W., Kubicki, M., Nestor, P. G., Dickie, E. W., Vassos, E., Ciufolini, S., Reis Marques, T., Crossley, N. A., Purcell, S. M., Smoller, J. W., van Haren, N. E. M., Toulopoulou, T., Donohoe, G., Goldstein, J. M., Seidman, L. J., McCarley, R. W. & Petryshen, T. L., May 2018, In: Schizophrenia Research. 195, p. 306-317 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

The Latent Taxonicity of Schizotypy in Biological Siblings of Probands with Schizophrenia

Linscott, R. J., Morton, S. E., Alizadeh, B. Z., Bartels-Velthuis, A. A., Van Beveren, N. J., Bruggeman, R., Cahn, W., De Haan, L., Delespaul, P., Meijer, C. J., Myin-Germeys, I., Kahn, R. S., Schirmbeck, F., Simons, C. J. P., Van Haren, N. E., Van Os, J. & Van Winkel, R., 6 Jun 2018, In: Schizophrenia Bulletin. 44, 4, p. 922-932 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

The role of cognitive functioning in the relationship between childhood trauma and a mixed phenotype of affective-anxious-psychotic symptoms in psychotic disorders

Mansueto, G., van Nierop, M., Schruers, K., Alizadeh, B. Z., Bartels-Velthuis, A. A., van Beveren, N. J., Bruggeman, R., Cahn, W., de Haan, L., Delespaul, P., Meijer, C. J., Myin-Germeys, I., Kahn, R. S., Schirmbeck, F., Simons, C. J. P., van Haren, N. E. M., van Os, J. & van Winkel, R., Feb 2018, In: Schizophrenia Research. 192, p. 262-268 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia

Olde Loohuis, L. M., Mangul, S., Ori, A. P. S., Jospin, G., Koslicki, D., Yang, H. T., Wu, T., Boks, M. P., Lomen-Hoerth, C., Wiedau-Pazos, M., Cantor, R. M., De Vos, W. M., Kahn, R. S., Eskin, E. & Ophoff, R. A., 1 Dec 2018, In: Translational Psychiatry. 8, 1, 96.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

Calafato, M. S., Thygesen, J. H., Ranlund, S., Zartaloudi, E., Cahn, W., Crespo-Facorro, B., Diez-Revuelta, A., Di Forti, M., Hall, M.-H., Iyegbe, C., Jablensky, A., Kahn, R., Kalaydjieva, L., Kravariti, E., Lin, K., McDonald, C., McIntosh, A. M., McQuillin, A., Picchioni, M. & Rujescu, D. & 9 others, Shaikh, M., Toulopoulou, T., Van Os, J., Vassos, E., Walshe, M., Powell, J., Lewis, C. M., Murray, R. M. & Bramon, E., 1 Sept 2018, In: British Journal of Psychiatry. 213, 3, p. 535-541 7 p.

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Open Access

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Voluntary or involuntary acute psychiatric hospitalization in Norway: A 24 h follow up study

Hustoft, K., Larsen, T. K., Brønnick, K., Joa, I., Johannessen, J. O. & Ruud, T., 28 Apr 2018, In: International Journal of Law and Psychiatry. 56, p. 27-34 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Scopus)

White matter abnormalities in 22q11.2 deletion syndrome patients showing cognitive decline

Nuninga, J. O., Bohlken, M. M., Koops, S., Fiksinski, A. M., Mandl, R. C. W., Breetvelt, E. J., Duijff, S. N., Kahn, R. S., Sommer, I. E. C. & Vorstman, J. A. S., 1 Jul 2018, In: Psychological Medicine. 48, 10, p. 1655-1663 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

White matter disruptions in patients with bipolar disorder

Abramovic, L., Boks, M. P. M., Vreeker, A., Verkooijen, S., van Bergen, A. H., Ophoff, R. A., Kahn, R. S. & van Haren, N. E. M., Jun 2018, In: European Neuropsychopharmacology. 28, 6, p. 743-751 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Widespread white matter microstructural differences in schizophrenia across 4322 individuals: Results from the ENIGMA Schizophrenia DTI Working Group

Kelly, S., Jahanshad, N., Zalesky, A., Kochunov, P., Agartz, I., Alloza, C., Andreassen, O. A., Arango, C., Banaj, N., Bouix, S., Bousman, C. A., Brouwer, R. M., Bruggemann, J., Bustillo, J., Cahn, W., Calhoun, V., Cannon, D., Carr, V., Catts, S. & Chen, J. & 138 others, Chen, J. X., Chen, X., Chiapponi, C., Cho, K. K., Ciullo, V., Corvin, A. S., Crespo-Facorro, B., Cropley, V., De Rossi, P., Diaz-Caneja, C. M., Dickie, E. W., Ehrlich, S., Fan, F. M., Faskowitz, J., Fatouros-Bergman, H., Flyckt, L., Ford, J. M., Fouche, J. P., Fukunaga, M., Gill, M., Glahn, D. C., Gollub, R., Goudzwaard, E. D., Guo, H., Gur, R. E., Gur, R. C., Gurholt, T. P., Hashimoto, R., Hatton, S. N., Henskens, F. A., Hibar, D. P., Hickie, I. B., Hong, L. E., Horacek, J., Howells, F. M., Hulshoff Pol, H. E., Hyde, C. L., Isaev, D., Jablensky, A., Jansen, P. R., Janssen, J., Jönsson, E. G., Jung, L. A., Kahn, R. S., Kikinis, Z., Liu, K., Klauser, P., Knöchel, C., Kubicki, M., Lagopoulos, J., Langen, C., Lawrie, S., Lenroot, R. K., Lim, K. O., Lopez-Jaramillo, C., Lyall, A., Magnotta, V., Mandl, R. C. W., Mathalon, D. H., McCarley, R. W., McCarthy-Jones, S., McDonald, C., McEwen, S., McIntosh, A., Melicher, T., Mesholam-Gately, R. I., Michie, P. T., Mowry, B., Mueller, B. A., Newell, D. T., O'Donnell, P., Oertel-Knöchel, V., Oestreich, L., Paciga, S. A., Pantelis, C., Pasternak, O., Pearlson, G., Pellicano, G. R., Pereira, A., Pineda Zapata, J., Piras, F., Potkin, S. G., Preda, A., Rasser, P. E., Roalf, D. R., Roiz, R., Roos, A., Rotenberg, D., Satterthwaite, T. D., Savadjiev, P., Schall, U., Scott, R. J., Seal, M. L., Seidman, L. J., Shannon Weickert, C., Whelan, C. D., Shenton, M. E., Kwon, J. S., Spalletta, G., Spaniel, F., Sprooten, E., Stäblein, M., Stein, D. J., Sundram, S., Tan, Y., Tan, S., Tang, S., Temmingh, H. S., Westlye, L. T., Tønnesen, S., Tordesillas-Gutierrez, D., Doan, N. T., Vaidya, J., Van Haren, N. E. M., Vargas, C. D., Vecchio, D., Velakoulis, D., Voineskos, A., Voyvodic, J. Q., Wang, Z., Wan, P., Wei, D., Weickert, T. W., Whalley, H., White, T., Whitford, T. J., Wojcik, J. D., Xiang, H., Xie, Z., Yamamori, H., Yang, F., Yao, N., Zhang, G., Zhao, J., Van Erp, T. G. M., Turner, J., Thompson, P. M. & Donohoe, G., 1 May 2018, In: Molecular Psychiatry. 23, 5, p. 1261-1269 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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1 Citation (Scopus)

2017

7T Proton Magnetic Resonance Spectroscopy of Gamma-Aminobutyric Acid, Glutamate, and Glutamine Reveals Altered Concentrations in Patients With Schizophrenia and Healthy Siblings

Thakkar, K. N., Rösler, L., Wijnen, J. P., Boer, V. O., Klomp, D. W. J., Cahn, W., Kahn, R. S. & Neggers, S. F. W., Mar 2017, In: Biological Psychiatry. 81, 6, p. 525–535 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Abnormal agency experiences in schizophrenia patients: Examining the role of psychotic symptoms and familial risk

Prikken, M., van der Weiden, A., Renes, R. A., Koevoets, G. J. C., Heering, H. D., Kahn, R. S., Aarts, H. & van Haren, N. E. M., 1 Apr 2017, In: Psychiatry Research. 250, p. 270-276 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Acute stress effects on GABA and glutamate levels in the prefrontal cortex: A 7T ¹H magnetic resonance spectroscopy study

Houtepen, L. C., Schür, R. R., Wijnen, J. P., Boer, V. O., Boks, M. P. M., Kahn, R. S., Joëls, M., Klomp, D. W. & Vinkers, C. H., 2017, In: Neuroimage: Clinical [E]. 14, p. 195-200 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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1 Downloads (Pure)

Affected Anatomical Rich Club and Structural-Functional Coupling in Young Offspring of Schizophrenia and Bipolar Disorder Patients

Collin, G., Scholtens, L. H., Kahn, R. S., Hillegers, M. H. J. & van den Heuvel, M. P., 15 Nov 2017, In: Biological Psychiatry. 82, 10, p. 746-755 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

An actigraphy study investigating sleep in bipolar I patients, unaffected siblings and controls

Verkooijen, S., van Bergen, A. H., Knapen, S. E., Vreeker, A., Abramovic, L., Pagani, L., Jung, Y., Riemersma-van der Lek, R., Schoevers, R. A., Takahashi, J. S., Kahn, R. S., Boks, M. P. M. & Ophoff, R. A., 15 Jan 2017, In: Journal of Affective Disorders. 208, p. 248-254 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

A network approach to psychosis: Pathways between childhood trauma and psychotic symptoms

Isvoranu, A. M., Van Borkulo, C. D., Boyette, L. L., Wigman, J. T. W., Vinkers, C. H., Borsboom, D., Kahn, R., De Haan, L., Van Os, J., Wiersma, D., Bruggeman, R., Cahn, W., Meijer, C., Myin-Germeys, I., 1 Jan 2017, In: Schizophrenia Bulletin. 43, 1, p. 187-196 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

36 Citations (Scopus)

An experience sampling study on the ecological validity of the SWN-20: Indication that subjective well-being is associated with momentary affective states above and beyond psychosis susceptibility

Pos, K., de Wit, I. E., van Dijk, F. A., Bartels-Velthuis, A. A., Bruggeman, R., Meijer, C. J., de Haan, L., Alizadeh, B. Z., Bartels-Velthuis, A. A., van Beveren, N. J. M., Bruggeman, R., Cahn, W., de Haan, L., Delespaul, P., Meijer, C. J., Myin-Germeys, I., Kahn, R. S., Schirmbeck, F., Simons, C. J. P. & van Haren, N. E. & 2 others, van Os, J. & van Winkel, R., Dec 2017, In: Psychiatry Research. 258, p. 234-238 5 p.

Research output: Contribution to journal › Article › Academic › peer-review

Changes in White Matter Organization in Adolescent Offspring of Schizophrenia Patients

de Leeuw, M., Bohlken, M. M., Mandl, R. C., Hillegers, M. H., Kahn, R. S. & Vink, M., 1 Jan 2017, In: Neuropsychopharmacology. 42, 2, p. 495–501 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Characterization of macrophages from schizophrenia patients

Ormel, P. R., Van Mierlo, H. C., Litjens, M., Van Strien, M. E., Hol, E. M., Kahn, R. S. & De Witte, L. D., 14 Nov 2017, In: npj Schizophrenia. 3, 1, 471.

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Connectome Disconnectivity and Cortical Gene Expression in Patients With Schizophrenia

Romme, I. A. C., de Reus, M. A., Ophoff, R. A., Kahn, R. S. & van den Heuvel, M. P., Mar 2017, In: Biological Psychiatry. 81, 6, p. 495–502 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., Gujral, M., Brandler, W. M., Malhotra, D., Wang, Z., Fuentes Fajarado, K. V., Maile, M. S., Ripke, S., Agartz, I., Albus, M. & Alexander, M. & 32 others, Amin, F., Atkins, J., Bacanu, S. A., Belliveau, R. A., Bergen, S. E., Bertalan, M., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Bulik-Sullivan, B., Byerley, W., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Cheng, W., Cloninger, C. R., Kahn, R. S., Murphy, K. C., van Os, J., Strengman, E., Ophoff, R. A., Psychosis Endophenotypes International Consortium & CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, 1 Jan 2017, In: Nature Genetics. 49, 1, p. 27-35 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

95 Citations (Scopus)

D-cycloserine addition to exposure sessions in the treatment of patients with obsessive-compulsive disorder

de Leeuw, A. S., van Megen, H. J. G. M., Kahn, R. S. & Westenberg, H. G. M., 1 Feb 2017, In: European Psychiatry. 40, p. 38-44 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

René Kahn

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