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No photo of Roger Adan
1993 …2026

Research activity per year

Personal profile

Biography

Roger Adan was trained as a molecular neurobiologist and received his PhD in 1992 on the regulation of vasopressin and oxytocin gene expression. Since 2002 he is full professor in molecular pharmacology. Via his work on melanocortin receptors he became an expert in molecular and neural pathways underlying feeding behavior, obesity and eating disorders. His lab has a strong multidisciplinary character. A variety of strategies (pharmacogenetics, viral vector technology, in vivo electrophysiology, optogenetics and automated behavioral and physiological analysis) is used to unravel mechanism underlying behavior.  The main focus is on feeding, since this is a natural behavior ideally suited to dissect neural circuits that underlie decision making, anxiety, anhedonia, impulsivity and reward seeking.

Personal fellowships and awards

1: NWO-VIDI grant (016.036.322): Role of neuropeptides in disorders of energy balance
2: ZOnMW-TOP grant (40-00812-98-14093): Shining light on loss of control over substance and food intake
3: co-applicant of 4 granted FP7 programs (Nudge-IT, NeuroFast, Full4Health and I.Family)
4: Recipient of the Rudolf Magnus Research Prize 2003
5: Recipient of the Organon prize for pharmacology 2004

Research line

Neural circuits of feeding and related behaviors

Fellowship & awards

1: NWO-VIDI grant (016.036.322): Role of neuropeptides in disorders of energy balance
2: TI pharma grant T5-210 Rapid in vivo CNS drug target validation and therapeutic potential by RNA-interference PI (and co-applicant on 2 other TI pharma grants)
3:co-applicant of 3 granted FP7 programs (NeuroFast, Full4Health and I.Family)
4: Recipient of the Rudolf Magnus Research Prize 2003
5: Recipient of the Organon prize for pharmacology 2004

External positions

commissielid NCAD - adviezen over proefdieren en proefdiervrije innovaties - RVO-NCAD

1 May 2022 → 31 Dec 3999

gasthoogleraarschap - adviseren molecular neuroscience technologie - Sahlgrenska Academy, university of Gothenburg

1 Jul 2018 → 31 Dec 3999

wetenschappelijk adviseur - translationeel werk: vertaalslag preklinisch onderzoek naar kliniek (en terug) - Altrecht- Rintveld eetstoornissen kliniek

1 Jan 2013 → 31 Dec 3999

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • A prefrontal cortex-lateral hypothalamus circuit controls stress-driven increased food intake

    Supiot, L. F., Kooij, K. L., Du, W., Benschop, A. A. C., Nicolson, A. S. J., Haak, R., Wolterink-Donselaar, I. G., Luijendijk, M. C. M., Riga, D., Adan, R. A. H., Poorthuis, R. B. & Meye, F. J., 25 May 2026, In: Nature Communications. 17, 1, 4620.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    2 Downloads (Pure)
  • FOXP1 is differentially active during development of murine vasopressin and oxytocin magnocellular neurons

    Berkhout, J. B., Trender, S., Krabichler, Q., Podpecan, Y., Franke, F., Schubert, T., Burbach, P., Grinevich, V., Adan, R., Fröhlich, H., Althammer, F., Meijer, O. C. & Mahfouz, A., 15 May 2026, In: iScience. 29, 5, 115604.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    3 Downloads (Pure)
  • Genomic meta-analyses of binge-eating behavior and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes

    Termorshuizen, J. D., Davies, H. L., Lee, S.-H., Dennis, J. K., Hübel, C., Johnson, J. S., Lu, Y., Munn-Chernoff, M. A., Peters, T., Qi, B., Schaumberg, K. E., Signer, R. H., Singh, K., Ter Kuile, A. R., Thornton, L. M., Xu, J., Yao, S., Yilmaz, Z., Zhang, R. & Zvrskovec, J. & 31 others, Abdulkadir, M., Ayorech, Z., Corfield, E. C., Havdahl, A., Krebs, K., Mack, T. M., Niarchou, M., Palviainen, T., Sealock, J. M., Baker, J. H., Bergen, A. W., Birgegård, A., Boraska Perica, V., Bühren, K., Burghardt, R., Cassina, M., Castellini, G., Collantoni, E., Crowley, J. J., Danner, U. N., Degenhardt, F., DeSocio, J. E., Dina, C., Dmitrzak-Węglarz, M., Duncan, L. E., Egberts, K. M., Adan, R. A., Kas, M. J., Luykx, J. J., Ophoff, R. A. & Disorders Working Group of the Psychiatric Genomics Consortium, Sept 2026, In: Nature Mental Health. 4, 9, p. 1361-1377 17 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
  • Impact of Voluntary Alcohol Consumption on Corticostriatal Plasticity in Rats

    Smeets, J. A. S., Ramakers, G. M. J., Meye, F. J., Baars, A.-M., Adan, R. A. H., Vanderschuren, L. J. M. J. & Lesscher, H. M. B., Jul 2026, In: European Journal of Neuroscience. 64, 1, e70602.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    2 Downloads (Pure)
  • Leptin Reduces Running in a Rodent Anorexia Nervosa Model via a Distributed Neural Network

    Papavoine, N. J. M., Veendijk, M. N., Nijman, J., Luijendijk, M. C. M., Wolterink-Donselaar, I. G., Meye, F. J. & Adan, R. A. H., Sept 2026, In: European Eating Disorders Review. 34, 5, p. 1314-1326 13 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    1 Downloads (Pure)
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