I am an associate professor in clinical trial methodology and statistics working within the Department of Data Science and Biostatistics of the Julius Center where I lead the Clinical Trial Methodology & Statistical Consultation team. My interests lie in innovative clinical trial methodology (both development and application) and adaptive methods, trials-within cohorts and trials in rare diseases in particular. I am the Trial Methodology Lead for U-TRIAL and workpackage leader for the Adaptive Trial Platform WP in the ONCODE-ACCELERATOR growthfund project. I am the chair of the UMC Utrecht's internal DSMB.  I also act as a methodology assessor (seconded) for the Dutch Medicines Evaluation Board (College ter Beoordeling van Geneesmiddelen: CBG-MEB). 

From July 2009 until April 2021 I worked at the Amsterdam UMC location VUmc as a researcher, a statistical consultant and methodology member of the hospital's institutional review board (METc).

I hold a PhD degree in Statistics from Eindhoven University of Technology (2007), a M.A. degree in Health Psychology from Tilburg University (2003) and a M.Sc. degree in Engineering Mathematics from Eindhoven University of Technology (2001). I have held postdoctoral research positions at the Southampton Statistical Sciences Research Institute S3RI (2007-2008) and TNO Quality of Life (2008-2009).