Research output per year
Research output per year
Personal profile
Biography
Dr Patricia Olofsen is a postdoc in the Center for Translational Immunology (CTI) at the University Medical Center Utrecht, the Netherlands. She obtained her PhD in 2021 at the Erasmus University on the molecular and cellular defects driving the leukemic progression of severe congenital neutropenia. Intrigued by neutrophils, cytokines and cancer, she joined the Leusen lab in 2021 to study the role of cytokines in attracting and activating neutrophils to kill tumor cells using IgA monoclonal antibodies.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Enhancing neutrophil cytotoxicity of a panel of clinical EGFR antibodies by Fc engineering to IgA3.0
Chan, C., Jansen, J. H. M., Hendriks, I. S. T., van der Peet, I. C., Verdonschot, M. E. L., Passchier, E. M., Tsioumpekou, M., Nederend, M., Klomp, S. A., Valerius, T., Peipp, M., Leusen, J. H. W. & Olofsen, P. A., 4 Sept 2024, In: MOLECULAR CANCER THERAPEUTICS. 23, 9, p. 1317-1331 15 p.Research output: Contribution to journal › Article › Academic › peer-review
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The Effect of Radiation Treatment of Solid Tumors on Neutrophil Infiltration and Function: A Systematic Review
Raymakers, L., Demmers, T. J., Meijer, G. J., Molenaar, I. Q., Santvoort, H. C. V., Intven, M. P. W., Leusen, J. H. W., Olofsen, P. A. & Daamen, L. A., 1 Nov 2024, In: International journal of radiation oncology, biology, physics. 120, 3, p. 845-861 17 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains
Stip, M. C., Jansen, J. H. M., Nederend, M., Tsioumpekou, M., Evers, M., Olofsen, P. A., Meyer-Wentrup, F. & Leusen, J. H. W., Sept 2023, In: Cancer Immunology, Immunotherapy. 72, 9, p. 3063-3077 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile13 Downloads (Pure) -
The Role of Cytokines in Neutrophil Development, Tissue Homing, Function and Plasticity in Health and Disease
Tsioumpekou, M., Krijgsman, D., Leusen, J. H. W. & Olofsen, P. A., Aug 2023, In: Cells. 12, 15, 24 p., 1981.Research output: Contribution to journal › Review article › peer-review
Open AccessFile12 Downloads (Pure) -
Truncated CSF3 receptors induce pro-inflammatory responses in severe congenital neutropenia
Olofsen, P. A., Bosch, D. A., de Looper, H. W. J., van Strien, P. M. H., Hoogenboezem, R. M., Roovers, O., van der Velden, V. H. J., Bindels, E. M. J., De Pater, E. M. & Touw, I. P., Jan 2023, In: British Journal of Haematology. 200, 1, p. 79-86 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access