Personal profile
Biography
- In 1986, Michiel Bots received his medical degree at the Erasmus University in Rotterdam. After working as a resident in Gynaecology and Obstetrics, at the Hospital Zonnegloren in Soest and as a resident in Surgery at the Juliana Hospital in Apeldoorn, he started in 1988 his training in cardiovascular epidemiology started at the Department of Epidemiology & Biostatistics of the Erasmus University Medical School in Rotterdam.
- In 1993, he obtained his PhD degree on the thesis entitled 'Carotid wall thickness as indicator of generalised atherosclerosis'.
- In 1996 he moved to the Julius Center for Health Sciences and Primary Care of the University Medical Center Utrecht in Utrecht.
- Since 1997 he serves as Managing (up to 2001) and Scientific director of Vascular Imaging Center Utrecht, a vascular core laboratory on quantification of structural, dynamic and functional arterial characteristics.
- In 2001 he was appointed associate professor in epidemiology
- Since 2009 he is a professor in the Epidemiology of Cardiovascular Disease at the University Medical Center Utrecht, Utrecht, The Netherlands.
- Since 2013 he is chariman of the steering committe of the Utrecht Cardiovascular Cohort: a multidisciplinary effort with physicians, patients and researchers of the UMC Utrecht, the UCC sets a benchmark for a learning cardiovascular healthcare system. UCC offers an invaluable resource for future high quality care as well as for first-class research for investigators.
His research activities comprise observational studies and clinical trials
- around the development of atherosclerosis, its physiological and environmental risk factors and its consequences. Non-invasive assessment of atherosclerotic abnormalities through imaging in both high risk and low risk populations by measurement of carotid intima-media thickness, carotid plaque, arterial stiffness, coronary calcifications, coronary stenosis and their progression over time are major topics in his studies.
- around uncontrolled hypertension elevated blood pressure and treatment thereof
- around kidney disease and its determinants and therapies, with a main focus on dialysis patients and treatment modalities
- around facts and figure of cardiovascular disease in the Netherlands, with an emphasis on national data obtainable through linkage of registries.
- around the creation of an infrastructure for uniform registration of cardiovascular information in routine clinical practice for patients referred for cardiovascular care at the University Medical Center Utrecht, the Netherlands
His scientific output involves over 750 international peer reviewed publications.
His teaching activities involve
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Regular curricular lectures on cardiovascular and general clinical epidemiology for medicine, biomedical and pharmaceutical bachelor and master students.
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Coordinator of the annual MSc course 'Cardiovascular Epidemiology' (www.msc-epidemiology.nl)
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Coordinator of the annual Blended MSc course ‘Epidemiology of Cardiovascular Disease’ (https://elearning.elevatehealth.eu/)
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Regularly a MSc course 'Clinical Epidemiology' outside the Netherlands (China, Germany, Malaysia)
Fellowship & awards
Over the years Michiel Bots was involved in national and international collaborations that were successful in obtaining grants proposal from profit (pharmaceutical industry) and non profit organisations (ZonMw, Netherlands Heart Foundation, European Union, Dutch Kidney Foundation, CVON-HF).
Personal webpage
Keywords
- RA0421 Public health. Hygiene. Preventive Medicine
- cardiovascular disease
- Clinical epidemiology
- children
- incidence
- prevalence
- R Medicine (General)
- Clinical epidemiology
- clinical trials
- atherosclerosis
- cardiovascular diease
- nephrology
Collaborations and top research areas from the last five years
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Characteristics of Populations Included in Randomized Controlled Trials of Hemodiafiltration and Registry Real-Life Populations: A Systematic Review
Cromm, K., Pham, N., Yuen, T., Jaha, H., Saglimbene, V., Hegbrant, J., Woodward, M., Davenport, A., Canaud, B., Barth, C., Rose, M., Blankestijn, P. J., Bots, M. L., Strippoli, G. F. & CONVINCE Scientific Committee and Investigators, Jan 2026, In: Clinical Journal of the American Society of Nephrology. 21, 1, p. 95-107 13 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Early mitral valve repair surgery versus active surveillance in asymptomatic severe primary mitral regurgitation-insights from the Dutch AMR registry
El Mathari, S., Hart, E. A., Jansen, R., Wind, A., Schaap, J., Cramer, M. J., Bots, M. L., Streukens, S. A. F., Wagenaar, L., Boekholdt, S. M., Bentala, M., Kluin, J. & Chamuleau, S. A. J., Mar 2026, In: Netherlands Heart Journal. 34, p. 90-99Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Haemorrhagic Safety Update of CLEAR-PATH: 30 Day and 12 Month Antiplatelet Therapy After Peripheral Angioplasty
Wegerif, E. C. J., Generaal, M. I., Vijn, L. J., van den Bor, R. M., van de Ven, P. M., Bots, M. L., de Borst, G. J. & Ünlü, Ç., 2026, In: EJVES Vascular Forum. 65, p. 32-39 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
The association of Life's Essential 8 with risk of stroke: The EPIC-NL prospective cohort study
Spronk, M., van der Schouw, Y. T., Te Hoonte, F., Verschuren, W. M. M., Bots, M. L., Vernooij, R. W. M. & Uijl, A., Mar 2026, In: NMCD : Nutrition metabolism and cardiovascular diseases. 36, 3, 6 p., 104419.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
A health economic evaluation of the multinational, randomized controlled CONVINCE trial - cost-utility of high-dose online hemodiafiltration compared to high-flux hemodialysis
Schouten, A. E. M., Fischer, F., Blankestijn, P. J., Vernooij, R. W. M., Hockham, C., Strippoli, G. F. M., Canaud, B., Hegbrant, J., Barth, C., Cromm, K., Davenport, A., Fischer, K. I., Rose, M., Török, M., Woodward, M., Bots, M. L., Ardine de Wit, G., Frederix, G. W. J., van der Meulen, M. P. & CONVINCE scientific committee, Apr 2025, In: Kidney International. 107, 4, p. 728-739 12 p., doi.org/10.1016/j.kint.2024.12.018.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure)
Activities
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The epidemiologie van slagaderverkalking van de slagaders in de hals
Bots, M. L. (Speaker)
23 May 2017Activity: Talk or presentation › Invited talk › Academic
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Mogelijkheden voor cohorten om te koppelen met landelijke registraties
Bots, M. L. (Speaker)
26 Jan 2017Activity: Talk or presentation › Invited talk › Academic
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'What do trials tell you, and what don't'
Bots, M. L. (Speaker)
6 Nov 2016Activity: Talk or presentation › Invited talk › Academic
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IVG Vaatlabcursus
Bots, M. L. (Invited speaker)
3 Nov 2016Activity: Participating in or organising an event › Participation in workshop, seminar, course › Academic
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Papendal course 'Vascular Biology'
Bots, M. L. (Speaker)
13 Oct 2016Activity: Talk or presentation › Invited talk › Academic