Personal profile
Biography
Matthijs Biesbroek obtained his medical degree in 2011 at Utrecht University. He received his PhD in Neurology after defending his thesis entitled "lesion-symptom mapping in vascular cognitive impairment" in 2016. He finished his training as neurologist at the UMC Utrecht in 2019. Het currently combines his clinical work as a neurologist at the Diakonessenhuis with his research on vascular cognitive impairment at the UMC Utrecht. His research focuses on location and patterns of vascular lesions in the brain as a source of new information on disease mechanisms and cognitive impact. He aims to use this information to develop tools that enable a more accurate diagnosis of the cause of cognitive decline in clinical practice, and an individualized cognitive prognosis after ischemic stroke. His research is funded by personal grants from the UMCU Brain Center (Rudolf Magnus Young Talent Fellowship in 2018), and ZonMw (VIMP grant, and off road grant in 2019).
Matthijs Biesbroek is sinds 2011 werkzaam in het UMC Utrecht. Hij studeerde geneeskunde aan de universiteit Utrecht en behaalde zijn artsexamen in 2011. In datzelfde jaar begon hij aan zijn opleiding tot neuroloog in het UMC Utrecht (opleiders prof. dr. J.H.J. Wokke en prof. dr. T. Seute), die hij in 2019 voltooide. In 2016 promoveerde hij op het proefschrift ‘lesion symptom-mapping in vascular cognitive impairment’. In 2019 deed hij een fellowship bij het Alzheimer Centrum van het VU medisch centrum in Amsterdam. Sinds 2020 is hij als neuroloog werkzaam in het Diakonessenhuis, en doet hij wetenschappelijk onderzoek in het UMC Utrecht. Zijn onderzoek richt zich op het belang van de locatie van vaatschade in de hersenen in relatie tot cognitief functioneren, met als doel om de diagnostiek en behandeling van patiënten met vasculaire cognitieve stoornissen te verbeteren.
External positions
Neuroloog - Patiëntenzorg - Diakonessenhuis
1 Jan 2022 → 31 May 2026
Collaborations and top research areas from the last five years
Research output
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Cerebral white matter hyperintensity volumes: Normative age- and sex-specific values from 15 population-based cohorts comprising 14,876 individuals
de Kort, F. A. S., Vinke, E. J., van der Lelij, E. J., Anblagan, D., Bastin, M. E., Beiser, A., Brodaty, H., Chaturvedi, N., Cheng, B., Cox, S. R., DeCarli, C., Enzinger, C., Fletcher, E., Frayne, R., de Groot, M., Huang, F., Ikram, M. A., Jiang, J., Lam, B. Y. K. & Maillard, P. & 20 others, , Feb 2025, In: Neurobiology of Aging. 146, p. 38-47 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile42 Downloads (Pure) -
Signature White Matter Hyperintensity Locations Associated With Vascular Risk Factors Derived From 15 653 Individuals
Biesbroek, J. M., de Kort, F. A. S., Anblagan, D., Bastin, M. E., Beiser, A., Brodaty, H., Chaturvedi, N., Chen, C. P. L. H., Cheng, B., Cheng, C.-Y., Cox, S. R., DeCarli, C., Enzinger, C., Fletcher, E., Frayne, R., de Groot, M., Hilal, S., Huang, F., Ikram, M. A. & Jiang, J. & 22 others, , Oct 2025, In: Stroke. 56, 10, p. 3047-3059 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Downloads (Pure) -
Tract-specific white matter hyperintensities and neuropsychiatric syndromes: a multicentre memory clinic study
Kan, C. N., Coenen, M., Xu, X., Hilal, S., Barkhof, F., Benke, T., Dal-Bianco, P., Decarli, C., Duering, M., Enzinger, C., Exalto, L. G., Fletcher, E. F., Hofer, E., Koek, H. L., Kuijf, H. J., Maillard, P. M., Moonen, J. E. F., Papma, J. M., Pijnenburg, Y. A. L. & Schmidt, R. & 10 others, , 12 Jun 2025, In: Journal of Neurology, Neurosurgery and Psychiatry. 96, 7, p. 697-704 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients
Alzheimer's Disease Neuroimaging Initiative, Apr 2024, In: Alzheimer's and Dementia. 20, 4, p. 2980-2989 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Downloads (Pure) -
Architecture and anatomy of executive processes: evidence from verbal fluency and Trail Making Test in 2009 stroke patients
MetaVCI map consortium, Sept 2024, In: Journal of Neurology. 271, 9, p. 6147-6159 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure)
Prizes
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UMC Utrecht, Rudolf Magnus Young Talent Fellowship
Biesbroek, M. (Recipient), 2018
Prize: Fellowship awarded competitively
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University Utrecht Neuroscience and Cognition, Seed grant.
Biesbroek, M. (Recipient), 2016
Prize: Fellowship awarded competitively
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