Research output per year
Research output per year
Personal profile
Research interests
Her research focuses on understanding the origin of chromosome segregation errors in mammalian oocytes and embryos. These errors are extremely common in human oocytes and embryos and are the primary cause of infertility and miscarriages in women. The main aims of her research are (1) to understand how, defects at the interface between chromosomes and the cytoskeletal machinery, lead to these errors and (2) to study the consequences of chromosome segregation errors during early development.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Breaking Trends: Large Animal Models to Study Spindle Assembly and Chromosome Segregation in Human Oocytes
Aparicio, A. L., Emerencia, T. & de Ruijter-Villani, M., 21 Aug 2025, Cellular Architecture and Dynamics in Female Meiosis. Springer, p. 139-160 22 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
Open AccessFile2 Downloads (Pure) -
Culture Conditions for the Development of Equine Oocytes
Baggio, C., Beitsma, M. M. & de Ruijter-Villani, M., 31 Aug 2025, Mammalian Oocyte Development: Methods and Protocols. Verlhac, M.-H. & Terret, M.-E. (eds.). 1 ed. New York: Humana Press, p. 9-19 11 p. (Methods in Molecular Biology; vol. 2946).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression
Wu, J., Larreategui-Aparicio, A., Lambers, M. L. A., Bodor, D. L., Klaasen, S. J., Tollenaar, E., de Ruijter-Villani, M. & Kops, G. J. P. L., 13 Mar 2023, In: Current Biology. 33, 5, p. 912-925.e6Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile17 Downloads (Pure) -
Parental genomes segregate into distinct blastomeres during multipolar zygotic divisions leading to mixoploid and chimeric blastocysts
De Coster, T., Masset, H., Tšuiko, O., Catteeuw, M., Zhao, Y., Dierckxsens, N., Aparicio, A. L., Dimitriadou, E., Debrock, S., Peeraer, K., de Ruijter-Villani, M., Smits, K., Van Soom, A. & Vermeesch, J. R., Dec 2022, In: Genome Biology. 23, 1, 201.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile14 Downloads (Pure) -
Compromised MPS1 Activity Induces Multipolar Spindle Formation in Oocytes From Aged Mares: Establishing the Horse as a Natural Animal Model to Study Age-Induced Oocyte Meiotic Spindle Instability
Rizzo, M., Stout, T. A. E., Cristarella, S., Quartuccio, M., Kops, G. J. P. L. & De Ruijter-Villani, M., 2021, In: Frontiers in Cell and Developmental Biology. 9, 657366.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure)