Personal profile
Biography
Fellowship & awards
UMCU-TKI grant 2023
KWF-TKI grant 2023
External positions
Chair of Scientific Advisory Board of Laigo Bio - Scientific advisory activities - Laigo Bio BV
1 Dec 2023 → 31 Dec 3999
Scientific advisor - Scientific advisory activities - Laigo Bio BV
1 Dec 2023 → 31 Dec 3999
Patent holder on inventive technology licensed to Laigo Bio BV - N/A - Laigo Bio BV
1 Jun 2023 → 31 Dec 3999
Grant Support ArgoBio - Ja - Grant support bij ArgoBio
1 Dec 2021 → 31 Dec 3999
Co-founder en shareholder bij Laigon Bio - Ja - Laigo Bio
1 Dec 2021 → 31 Dec 3999
Lid van research management committee bij Oncode Institute - Ja - Oncode Institute
1 Jan 2018 → 31 Dec 3999
Member of Research Council KWF - Ja - KWF
1 Jan 2018 → 31 Dec 3999
Collaborations and top research areas from the last five years
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Hepatocellular carcinoma-linked AXIN1 mutations drive low Wnt/β-catenin activity enabling niche-independent growth and YAP/TAZ signaling
Venhuizen, A. J., van Os, Y., Kaptein, M. L., Aarts, M. T., Xanthakis, D., Jordens, I. & Maurice, M. M., 16 Jan 2026, In: iScience. 29, 1, 20 p., 114501.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure) -
Intestinal LKB1 Loss Drives a Premalignant Program Along the Serrated Cancer Pathway
Plugge, S. F., Ma, H., van der Vaart, J. Y., Sprangers, J., Morsink, F. H. M., Xanthakis, D., Jamieson, C., Stroot, K. B. W., Keijzer, A. R., Margaritis, T., Candelli, T., Straver, R., de Ridder, J., Holstege, F. C. P., de Leng, W. W. J., Offerhaus, G. J. A., Merenda, A. & Maurice, M. M., Feb 2026, In: Gastroenterology. 170, 2, p. 298-314 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure) -
WNT7B drives a program for pancreatic cancer subtype switching and progression
Sprangers, J., Bugter, J. M., Xanthakis, D., Boekhout, M., Kok, R. N. U., Geurts, V. E., Clevers, H., Brosens, L. A. A., Dijk, F., Rodríguez Colman, M. J., van der Vaart, J. Y. & Maurice, M. M., 20 Mar 2026, In: iScience. 29, 3, 25 p., 115050.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
BRAFV600E augments WNT signaling in colorectal cancer via aberrant DNA methylation
El Bouazzaoui, L., Bugter, J. M., Küçükköse, E., Verheem, A., Post, J. B., Fenderico, N., Borel Rinkes, I. H. M., Snippert, H. J. G., Maurice, M. M. & Kranenburg, O., 18 Jul 2025, In: iScience. 28, 7, 16 p., 112708.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile18 Downloads (Pure) -
BRAFV600E maintains the CpG island methylator phenotype, and DNA methylation of PRC2 targets genes in colon cancer
El Bouazzaoui, L., Bugter, J. M., Küçükköse, E., Verheem, A., Post, J. B., Fenderico, N., Borel Rinkes, I. H. M., Snippert, H. J. G., Maurice, M. M. & Kranenburg, O., 18 Jul 2025, In: iScience. 28, 7, 112905.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Downloads (Pure)