Supervised Work
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2026
Diagnostic Utility of Saliva in Molecular Carriage Surveillance of Vaccine-Targeted Bacterial Pathogens: A Spitting Image
Miellet, W., 10 Feb 2026, Utrecht University. 385 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile18 Downloads (Pure) -
2025
Pertussis Immunization Before 24 Weeks of Pregnancy: Maternal Antibody Transfer, Reactogenicity and Acceptance
Immink, M., 13 Feb 2025, Utrecht University. 309 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile16 Downloads (Pure) -
2024
Antibody responses and B cell immunity after pertussis booster vaccination: immunity in young and old in times of endemic pertussis
Versteegen, P., 28 May 2024, Utrecht: Utrecht University. 244 p.Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)
Open AccessFile2 Downloads (Pure) -
2023
The early-life microbiota in relation to mucosal immune maturation and respiratory infections in children
de Koff, E., 11 Apr 2023, Utrecht: Utrecht University. 265 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile39 Downloads (Pure) -
Vaccine-induced immunity and protection against invasive meningococcal serogroup ACWY disease in the Netherlands
Ohm, M., 23 May 2023, Utrecht: Utrecht University. 198 p.Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)
Open AccessFile13 Downloads (Pure) -
2021
The infant gut microbiome and resistome in health and disease
Reyman, M., 1 Jul 2021, Utrecht University. 258 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile23 Downloads (Pure) -
2020
The 2013-2014 measles outbreak in The Netherlands: New evidence on measles epidemiology and control
Woudenberg, T., 23 Jan 2020, [Utrecht]: Utrecht University. 252 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile3 Downloads (Pure) -
2019
Epidemiology of varicella zoster virus in the Netherlands: Implications for vaccination strategies
van Lier, E. A., 12 Nov 2019, [Utrecht]: Utrecht University. 280 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile8 Downloads (Pure) -
Improving diagnosis of bacterial infections: Research without gold standard
van Houten, C. B., 22 Jan 2019, Utrecht University. 215 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile3 Downloads (Pure) -
The role of the upper respiratory tract microbiota in childhood respiratory infections
Man, W. H., 13 Jun 2019, Utrecht University. 254 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile5 Downloads (Pure) -
2018
Persistence of pertussis immunity in children and adults; Influence of priming vaccination
van der Lee, S., 5 Apr 2018, Utrecht University. 171 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile6 Downloads (Pure) -
Pneumococcal disease and vaccinations in older adults
van Deursen, A. M. M., 7 Jun 2018, Utrecht University. 209 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile17 Downloads (Pure) -
Respiratory tract microbiota: gatekeeper to respiratory health
de Steenhuijsen Piters, W. A. A., 25 Oct 2018, Utrecht University. 289 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile13 Downloads (Pure) -
Vaccine-preventable diseases: evaluation of vaccination programmes and optimisation of surveillance
van der Maas, N. A. T., 12 Jun 2018, Utrecht University. 246 p.Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)
Open AccessFile6 Downloads (Pure) -
2017
Cellular and humoral immunity after infection with B. pertussis: the role of age, antigen and vaccination history
van Twillert, I., 15 Feb 2017, Utrecht University. 210 p.Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)
Open AccessFile5 Downloads (Pure) -
Connecting clinical and molecular disease features in Common Variable Immunodeficiency Disorder
Janssen, W. J. M., 20 Apr 2017, Utrecht University. 190 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile64 Downloads (Pure) -
Optimizing meningococcal vaccination strategies in adolescents: Carriage, timing of vaccination and antibody dynamics
van Ravenhorst, M. B., 12 Oct 2017, Utrecht University. 174 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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The development of the respiratory microbiota and its role in respiratory disease
Bosch, A., 26 Jan 2017, Utrecht University. 214 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile6 Downloads (Pure) -
2016
Early-life development of the respiratory microbiome: -cystic fibrosis and healthy infants-
Prevaes, S., 15 Dec 2016, Utrecht University. 237 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile4 Downloads (Pure) -
Molecular surveillance of pneumococcal carriage in all ages
Wyllie, A., 22 Sept 2016, Utrecht University. 267 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile4 Downloads (Pure) -
2015
Cell-biological mechanisms regulating antigen presentation: Signaling towards adaptive immunity
Compeer, E. B., 22 May 2015, 253 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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Invasive meningococcal disease and prevention through vaccination: Towards an optimal meningococcal serogroup C vaccination schedule
Stoof, S. P., 12 Nov 2015, Utrecht University. 209 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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2014
Dynamics and drivers of the respiratory microbiome in healthy infants
Biesbroek, G., 22 May 2014, Utrecht University. 259 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile4 Downloads (Pure) -
Mechanisms involved with immune hyperresponsiveness in newborns infected with respiratory viruses
Stoppelenburg, A. J., 28 Mar 2014, Utrecht University. 153 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile2 Downloads (Pure) -
Pertussis specific T-cell immunity in Dutch children: Differences after whole-cell versus acellular vaccination
Schure, R. M., 25 Feb 2014, Utrecht University. 124 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile3 Downloads (Pure) -
2013
Host and microbe characteristics of pneumococcal colonization in elderly
Krone, C. L., 29 Oct 2013, Utrecht University. 155 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile5 Downloads (Pure) -
Nasopharyngeal colonization with respiratory pathogens
van den Bergh, M. R., 19 Apr 2013, Utrecht University. 171 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile27 Downloads (Pure) -
Pneumococcal conjugate vaccines; impact on nasopharyngeal bacterial carriage and optimizing vaccination strategies
Spijkerman, J., 10 Oct 2013, Utrecht University. 205 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile7 Downloads (Pure) -
Type 1 diabetes and obesity in children : Focus on inflammation
Verrijn Stuart, A. A., 4 Dec 2013, Utrecht University. 240 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile14 Downloads (Pure) -
2011
Common variable immunodeficiency to solve the variable of the equation
van de Ven, A. A. J. M., 24 Nov 2011, Utrecht University. 257 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile5 Downloads (Pure) -
Immunity and infectious morbidity in childhood ALL treatment : the benefits of intensity reduction
van Tilburg, C. M., 22 Mar 2011, Utrecht University. 181 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile2 Downloads (Pure) -
Pertussis vaccinations in Dutch children: memory immune responses
Hendrikx, L. H., 8 Dec 2011, Utrecht University. 176 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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Pneumococcal conjugate vaccination : clinical impact, reduced-dose schedules and immunologic responses
Rodenburg, G. D., 17 Mar 2011, Utrecht University. 249 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile6 Downloads (Pure) -
Reduced-dose schedules with pneumococcal conjugate vaccine: impact on nasopharyngeal carriage and herd immunity
van Gils, E. J. M., 6 Sept 2011, Utrecht: Utrecht University. 172 p.Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile3 Downloads (Pure) -
2010
Adenoviral Infections in the immunocompromised host towards tailor-made therapy
Translated title of the contribution :Adenoviral Infections in the immunocompromised host towards tailor-made therapy Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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Management of chronic mucosal otitis media in children
Translated title of the contribution :Management of chronic mucosal otitis media in children Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile2 Downloads (Pure) -
Meningococcal C specific immune responses: immunity in an era of immunization with vaccine
Translated title of the contribution :Meningococcal C specific immune responses: immunity in an era of immunization with vaccine Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile6 Downloads (Pure) -
2009
Frequent respiratory tract infections in children. The role of environmental and genetic factors.
Translated title of the contribution :Frequent respiratory tract infections in children. The role of environmental and genetic factors. Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile3 Downloads (Pure) -
Towards a safer stem cell transplantation: Insights into viral reactivations and immune reconstitution.
Translated title of the contribution :Towards a safer stem cell transplantation: Insights into viral reactivations and immune reconstitution. Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile4 Downloads (Pure) -
2008
Prognosis in Cystic Fibrosis: Trends and Predictors
Translated title of the contribution :Prognosis in Cystic Fibrosis: Trends and Predictors Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile1 Downloads (Pure) -
2007
Extending recommendations for respiratory vaccines: experimental and non-experimental studies.
Translated title of the contribution :Extending recommendations for respiratory vaccines: experimental and non-experimental studies. Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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ISS immune modulation, vaccination and the regulation of arthritis. Controlling arthritis through vaccination.
Translated title of the contribution :ISS immune modulation, vaccination and the regulation of arthritis. Controlling arthritis through vaccination. Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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2006
The role of childhood respiratory tract infections in the development of asthma and atopic disease.
Translated title of the contribution :The role of childhood respiratory tract infections in the development of asthma and atopic disease. Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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2005
Fc gamma receptors in the Clinic
Translated title of the contribution :Fc gamma receptors in the Clinic Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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Innate and adaptive immunity in otitis media.
Translated title of the contribution :Innate and adaptive immunity in otitis media. Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
Open AccessFile47 Downloads (Pure) -
2004
Neutropenia and Thrombocytopenia in children: clinical relevance of old and new laboratory tests.
Translated title of the contribution :Neutropenia and Thrombocytopenia in children: clinical relevance of old and new laboratory tests. Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)
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2003
Health related quality of life in children with recurrent acute otitis media
Translated title of the contribution :Health related quality of life in children with recurrent acute otitis media Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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The pathogenesis of S. pneumoniae infections.
Translated title of the contribution :The pathogenesis of S. pneumoniae infections. Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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2002
Antibodies & S.pneumoniae
Translated title of the contribution :Antibodies & S.pneumoniae Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)
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2001
Clinical and experimental studies with pneumococcal and Haemophilus influenza type b conjugate vaccines.
Translated title of the contribution :Clinical and experimental studies with pneumococcal and Haemophilus influenza type b conjugate vaccines. Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)