Research output per year
Research output per year
Personal profile
Biography
Lennie is an ICU consultant with a background in infectious diseases and epidemiology. She co-leads (with Olaf Cremer) the "epidemiology of sepsis and inflammation" research group at the Intensive Care Center of the UMCU, supervising 8 PhDs and 2 postdoctoral researchers. Her research focuses on clinical trials in critically ill patients, especially those with sepsis and severe infections. Lennie is the European lead and immediate past chair of the global TSC of REMAP-CAP, and a co-applicant and work package leader on EU-funded projects like RECOVER and ECRAID-Base. Lennie leads the ZonMw funded IMPRINT consortium and is co-applicant on several international collaborative grants. She is a member of several DSMBs, guideline committees and advisory committees (all unpayed), and a member of the ESICM executive committee as the Education and Training Committee lead.
Biography
KEY TEACHING ACTIVITIES
Faculty ESICM Sustainability Masterclass 2024-present
Faculty ESICM Research Masterclass 2022-present
Faculty ESICM Sepsis and Severe Infections Masterclass 2017-present
Faculty and organizer Dutch ICU Fellows Education on Infectious Diseases in ICU 2013-present
CONFERENCES and SEMINARS
Invited (inter-)national speaker for NVIC, CCR, ESICM, ISICEM (Keynote), ERS, Weimar sepsis update, ANZICS/ACCCN ASM (Keynote), International Sepsis Forum, and several Dutch national conferences.
SERVICE
UMCU internal DSMB 2024-present
Co-vice chair (ESICM) Surviving Sepsis Campaign 2023-present
Surviving Sepsis Campaign Research Committee 2023-present
EMPRESS DSMB 2023-present
Ecraid Coordinating Committee 2022-present
ESICM Executive Committee 2022-present
Chair ESICM Education and Training Committee 2022-present
Member International Advisory Board of Sepsis Canada 2021-present
Chair International Trial Steering Committee REMAP-CAP 2021-2023
Member “Pandemic Preparedness Plan” committee for Dutch National Academy of Sciences (KNAW) 2021-2022
Taskforce Acute Infectious Threats for Dutch National ICU Society (NVIC) 2018-present (chair 2019-2021)
Education/Academic qualification
PhD "Controlling Antibiotic Resistance in the ICU", Julius Center
2007 → 2013
MSc Medicine, Vrije Universiteit
1994 → 1999
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial
3 Jan 2023, In: JAMA - The Journal of The American Medical Association. 329, 1, p. 39-51 13 p.Research output: Contribution to journal › Article › Academic › peer-review
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Interleukin-6 receptor antagonists in critically ill patients with covid-19
22 Apr 2021, In: The New England journal of medicine. 384, 16, p. 1491-1502 12 p.Research output: Contribution to journal › Article › Academic › peer-review
922 Citations (Scopus) -
Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients with COVID-19: A Randomized Clinical Trial
5 Apr 2022, In: JAMA - The Journal of The American Medical Association. 327, 13, p. 1247-1259 13 p.Research output: Contribution to journal › Article › Academic › peer-review
1 Citation (Scopus) -
Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial
2 Nov 2021, In: JAMA - The Journal of The American Medical Association. 326, 17, p. 1690-1702 13 p.Research output: Contribution to journal › Article › Academic › peer-review
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Therapeutic anticoagulation with heparin in critically ill patients with covid-19
26 Aug 2021, In: The New England journal of medicine. 385, 9, p. 777-789 13 p.Research output: Contribution to journal › Article › Academic › peer-review
10 Citations (Scopus)