20022024

Research activity per year

Personal profile

Research interests

  1. Our research group focuses on biofabrication and biomaterials design, in particular for the regeneration of (osteo) chondral defects. We are developing novel biofabriaction strategies, as well and “bioinks” for 3D printing. These hydrogel-based “inks” are both designed to drive specific differentiation of the embedded and/or endogenous cells, as well as to allow fabrication with high shape fidelity in order to generate constructs that are a blueprint of the real tissue. In addition, we are adopting bioreactor technology to mature the generated tissue constructs. Finally, approaches towards the translation of the constructs in veterinary (equine) and human clinics are pursued, including its use as an in vitro platform for testing. 

    Areas of interest 
    - Joint regeneration 
    - Biofabrication 

    - Biomaterial development

    - Bioreactors

    - Extracellular matrix-derived scaffolds 

    - Nutrient limitation 

Personal webpage

https://rmutrecht.org/jos-malda-phd/

Biography

  1. Our research group focuses on biofabrication and biomaterials design, in particular for the regeneration of (osteo) chondral defects. We are developing novel biofabriaction strategies, as well and “bioinks” for 3D printing. These hydrogel-based “inks” are both designed to drive specific differentiation of the embedded and/or endogenous cells, as well as to allow fabrication with high shape fidelity in order to generate constructs that are a blueprint of the real tissue. In addition, we are adopting bioreactor technology to mature the generated tissue constructs. Finally, approaches towards the translation of the constructs in veterinary (equine) and human clinics are pursued, including its use as an in vitro platform for testing. 

    Areas of interest 
    - Joint regeneration 
    - Biofabrication 

    - Biomaterial development

    - Bioreactors

    - Extracellular matrix-derived scaffolds 

    - Nutrient limitation 

Fellowship & awards

Anna Prize 2017, Anna Foundation and Nederlandse Orthopaedische Vereniging

Nanonica Prize 2015 for the breakthrough of the year in the field of nanotechnology, Nanonica Europe

ERC Consolidator Grant ERC-2014-CoG_647426

NWO Veni FellowshipPrinten van levend kraakbeen 

Side activities

Hoogleraar Biofabrication in Translational Regenerative Medicine (0,7FTE), Afdeling Orthopaedie, UMC Utrecht
Secretary General van de International Cartilage Repair and Joint Restoration Society (ICRS; 2022-2023)
Voormalig President van de International Society for Biofabrication (ISBF; 2014-2018)
Board member International Society for Biofabrication (ISBF; 2014-2022)
Scientific Advisor, SentryX B.V.

External positions

Associate Professor

1 Jan 2012 → …

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • 3D Printed Magneto-Active Microfiber Scaffolds for Remote Stimulation and Guided Organization of 3D In Vitro Skeletal Muscle Models

    Cedillo-Servin, G., Dahri, O., Meneses, J., van Duijn, J., Moon, H., Sage, F., Silva, J., Pereira, A., Magalhães, F. D., Malda, J., Geijsen, N., Pinto, A. M. & Castilho, M., 22 Mar 2024, In: Small. 20, 12, p. 1-16 16 p., 2307178.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
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  • Covalent Grafting of Functionalized MEW Fibers to Silk Fibroin Hydrogels to Obtain Reinforced Tissue Engineered Constructs

    Viola, M., Ainsworth, M. J., Mihajlovic, M., Cedillo-Servin, G., van Steenbergen, M. J., van Rijen, M., de Ruijter, M., Castilho, M., Malda, J. & Vermonden, T., 11 Mar 2024, In: Biomacromolecules. 25, 3, p. 1563-1577 15 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
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    4 Downloads (Pure)
  • Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction

    Rosales, R. M., Mountris, K. A., Oliván-Viguera, A., Pérez-Zabalza, M., Cedillo-Servin, G., Iglesias-García, O., Hrynevich, A., Castilho, M., Malda, J., Prósper, F., Doblaré, M., Mazo, M. M. & Pueyo, E., Mar 2024, In: Computers in Biology and Medicine. 171, 108044.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
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    7 Downloads (Pure)
  • How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?

    Davis, T., Tabury, K., Zhu, S., Angeloni, D., Baatout, S., Benchoua, A., Bereiter-Hahn, J., Bottai, D., Buchheim, J. I., Calvaruso, M., Carnero-Diaz, E., Castiglioni, S., Cavalieri, D., Ceccarelli, G., Choukér, A., Cialdai, F., Ciofani, G., Coppola, G., Cusella, G., Degl’Innocenti, A., & 40 othersDesaphy, J. F., Frippiat, J. P., Gelinsky, M., Genchi, G., Grano, M., Grimm, D., Guignandon, A., Hahn, C., Hatton, J., Herranz, R., Hellweg, C. E., Iorio, C. S., Karapantsios, T., van Loon, J. J. W. A., Lulli, M., Maier, J., Malda, J., Mamaca, E., Morbidelli, L., van Ombergen, A., Osterman, A., Ovsianikov, A., Pampaloni, F., Pavezlorie, E., Pereda-Campos, V., Przybyla, C., Puhl, C., Rettberg, P., Rizzo, A. M., Robson-Brown, K., Rossi, L., Russo, G., Salvetti, A., Santucci, D., Sperl, M., Tavella, S., Thielemann, C., Willaert, R., Szewczyk, N. & Monici, M., 10 Feb 2024, In: npj Microgravity. 10, 1, 7 p., 16.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
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    6 Downloads (Pure)
  • How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?

    Willis, C. R. G., Calvaruso, M., Angeloni, D., Baatout, S., Benchoua, A., Bereiter-Hahn, J., Bottai, D., Buchheim, J. I., Carnero-Diaz, E., Castiglioni, S., Cavalieri, D., Ceccarelli, G., Chouker, A., Cialdai, F., Ciofani, G., Coppola, G., Cusella, G., Degl’Innocenti, A., Desaphy, J. F., Frippiat, J. P., & 36 othersGelinsky, M., Genchi, G., Grano, M., Grimm, D., Guignandon, A., Herranz, R., Hellweg, C., Iorio, C. S., Karapantsios, T., van Loon, J., Lulli, M., Maier, J., Malda, J., Mamaca, E., Morbidelli, L., Osterman, A., Ovsianikov, A., Pampaloni, F., Pavezlorie, E., Pereda-Campos, V., Przybyla, C., Rettberg, P., Rizzo, A. M., Robson-Brown, K., Rossi, L., Russo, G., Salvetti, A., Risaliti, C., Santucci, D., Sperl, M., Tabury, K., Tavella, S., Thielemann, C., Willaert, R., Monici, M. & Szewczyk, N. J., 1 May 2024, In: npj Microgravity. 10, 1, p. 1-5 5 p., 50.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
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