Personal profile
Biography
Jan Lagendijk's research focus is the application of MRI in radiotherapy. MRI is used for all aspects of radiotherapy. With MRI it is possible to find and characterize tumours. Jan Lagendijk is developing the MRI linac system to visualize the tumour and its surrounding tissues, in real time, at the moment of treatment. This to guide and optimize treatment and to prevent that normal tissues are being irradiated. Jan Lagendijk also uses MRI for response assessment, to quantify the impact of treatments. His motto is ‘See what you treat’. The technology, he develops, must create the next generation radiotherapy standard. Together with Elekta and Philips he is introducing this MRI technology in routine clinic.
See here a movie explaining MR Linac >
See here the UMCU page of Radiotherapy >
Personal webpage
https://www.youtube.com/watch?v=4m9GWS6AUK8
http://www.umcutrecht.nl/nl/Ziekenhuis/Zorgverleners/Lagendijk-JJW
Fellowship & awards
ESHO award for life time achievement in hyperthermia
Collaborations and top research areas from the last five years
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Tumor burden in metastatic colorectal cancer quantified using deep learning models: Prognostic value and maintenance treatment benefit in the CAIRO3 trial
Al-Toma, D., Kemna, R., Ali, M., Zwart, K., Zeeuw, M. J., Stehouwer, B. L., de Jong, P. A., Kurk, S., Braat, M. N. G. J. A., Lagendijk, J. J. W., May, A. M., Koopman, M., Verpalen, I. M., Swijnenburg, R. J., Punt, C. J. A., Kazemier, G. & Bol, G. M., 2 May 2026, In: European Journal of Cancer. 238, 10 p., 116668.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Downloads (Pure) -
Reconstructed dose and geometric coverage for tight margins using intrafraction re-planning on an integrated magnetic resonance imaging and linear accelerator system for prostate cancer patients
van den Berg, I., Zachiu, C., de Groot-van Breugel, E. N., Willigenburg, T., Bol, G. H., Lagendijk, J. J. W., Raaymakers, B. W., van Melick, H. H. E., van den Berg, C. A. T., van der Voort van Zyp, J. R. N. & de Boer, J. C. J., Apr 2025, In: Physics and Imaging in Radiation Oncology. 34, 100776.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Downloads (Pure) -
Feasibility and safety of single-fraction sub-ablative radiotherapy with systemic therapy in colorectal cancer patients with ≤ 10 metastases: A multicenter pilot study (NCT05375708)
Zwart, K., Braat, M. N. G. J. A., van der Baan, F. H., May, A. M., Roodhart, J. M. L., Al-Toma, D., Otten, J. M. M. B., Los, M., Oostergo, T., Fijneman, R. J. A., van Dodewaard-de Jong, J. M., Punt, C. J. A., Meijer, G., Lagendijk, J. J. W., Koopman, M., Intven, M. & Bol, G. M., Nov 2024, In: Clinical and translational radiation oncology. 49, p. 1-5 5 p., 100874.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile13 Downloads (Pure) -
Robotic MR-guided high dose rate brachytherapy needle implantation in the prostate (ROBiNSon)—a proof-of-concept study
Rasing, M. J. A., van Schelven, L. J., van Lier, A. L. H. M. W., Boskovic, E., van Son, M., Schokker, R. I., van Vliet-Van den Ende, K. M., Kelder, D. D., Verkerk, J., van de Pol, S. M. G., Lagendijk, J. J. W., Peters, M., van der Voort van Zyp, J. R. N. & Moerland, M. A., 7 Sept 2024, In: Physics in medicine and biology. 69, 17, 14 p., 175011.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Downloads (Pure) -
Subgroup analyses of the phase 3 CAIRO3 trial: Association of number and total volume of metastases on survival in patients with metastatic colorectal cancer based on a deep-learning automatic segmentation model
Zwart, K., Zeeuw, M. J., Stehouwer, B. L., Al-Toma, D., Kurk, S., Braat, M. N. G. J. A., de Jong, P. A., Lagendijk, J. J. W., May, A. M., Koopman, M., Punt, C. J. A., Kazemier, G. & Bol, G., 22 Jan 2024, In: Journal of Clinical Oncology. 42, 3, 130.Research output: Contribution to journal › Meeting Abstract › Academic