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Jeroen Hendrikse

Jeroen Hendrikse

prof. dr.

    20012026

    Research activity per year

    Personal profile

    Biography

    The overall aim of prof. Hendrikse’s research is to understand the cause of ischemic stroke with a focus on the three P’s: Pipes (vessel and vessel walls), Perfusion (CBF and reserve capacity) and Parenchyma (brain tissue and tissue changes/infarcts). After his PhD in 2004 he has created a new research field with technical development and clinical applications of MR methods of cerebral perfusion (so called arterial spin labeling MRI) and intracranial vessel wall imaging. His original MR research is recognized by the international research field with European grants (FP7, Biocog; WP leader) and personal national excellence grants (ERC-StG, VIDI, VENI, Heart association, Technical Research Council), chairmanship of international (ISMRM) perfusion study group, steering committee member of Carotid Stenosis Triallists Collaboration (CSTC), invited lectures, reviews, white papers and book chapters. 22 of his publications are within international collaborations (including Johns Hopkins University and Vanderbilt University, USA). He has over 30 publications within the field of 7T MRI brain imaging method developments. In the radiology and neurovascular research arena ‘RADIOLOGY and ‘STROKE’ are leading journals: he has over 30 publications in these journals. He is the first radiologist awarded with a VIDI grant and an ERC-StG. The focus of his research group is to understand the relation between the ‘3Ps’: pipes (arterial vasculature), perfusion and parenchyma (brain tissue damage) by using innovative imaging methods. Early 2017 he was appointed Chairman of Radiology and Nuclear Medicine UMC Utrecht.

     

    Research line

    Brain MRI: Pipes, Perfusion, Parenchyma

    Most recent key publications

    1: Dieleman N, Van der Kolk AG. Hendrikse J. MR intracranial vessel wall imaging: current prospects and future directions. Circulation. 2014 Jul 8;130(2):192-201
    2: De Vis JB, Petersen ET, Bhogal A, Hartkamp NS, Klijn CJ, Kappelle LJ, Hendrikse J. Calibrated MRI to evaluate cerebral hemodynamics in patients with an internal carotid artery occlusion. J Cereb Blood Flow Metab. 2015 Jun;35(6):1015-23
    3: Van der Kolk AG, Zwanenburg JJ, Brundel M, Biessels GJ, Visser F, Luijten PR, Hendrikse J. Distribution and natural course of intracranial vessel wall lesions in patients with ischemic stroke or TIA at 7.0 Tesla MRI. Eur Radiol. 2015 Jun;25(6):1692-700
    4: De Rotte AA, Truijman MT, van Dijk AC, Liem MI, Schreuder FH, van der Kolk AG, de Kruijk JR, Daemen MJ, van der Steen AF, de Borst GJ, Luijten PR, Nederkoorn PJ, Kooi ME, van der Lugt A, Hendrikse J. Plaque components in symptomatic moderately stenosed carotid arteries related to cerebral infarcts: the plaque at RISK study. Stroke. 2015 Feb;46(2):568-71
    5: Hendrikse J, Van der Grond J, Lu H, Van Zijl PCM, Golay X. Flow territory mapping of the cerebral arteries with MRI. Stroke. 2004;35:882-887

    Fellowship & awards

    1: ERC-StG
    2: VENI and VIDI
    3: FP7-WP-Leader
    4: Dutch Heart Association
    5: STW/Technical Research Council

    External positions

    lid Raad van Toezicht - lid Raad van Toezicht - Instituut Verbeeten

    1 Oct 2023 → 31 Dec 3999

    Collaborations and top research areas from the last five years

    Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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    • Aneurysm Wall Enhancement and Probability of Instability in Unruptured Intracranial Aneurysms: A Long-Term Follow-Up Study

      van der Kamp, L. T., Kamphuis, M. J., Naggara, O., Le Tat, T., Rinkel, G. J. E., de Kort, G. A. P., van Eijk, R. P. A., Hendrikse, J., van der Schaaf, I. C. & Vergouwen, M. D. I., Apr 2026, In: Annals of Neurology. 99, 4, p. 863-870 8 p.

      Research output: Contribution to journal › Article › Academic › peer-review

      Open Access
      File
      3 Downloads (Pure)

    • Association of Enlarged Perivascular Spaces and Total Small Vessel Disease Burden With Kidney Function

      Nash, P. S., Ambler, G., Best, J. G., Wilson, D., Du, H., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Goeldlin, M. B., Beyeler, M., Bücke, P., El-Koussy, M., Mattle, H. P., Panos, L., van Dam-Nolen, D. H. K., Dubost, F., Hendrikse, J., Kooi, M. E., Mess, W. H. & Nederkoorn, P. J. & 54 others, Christ, N., Bellut, M., Gunkel, S., Karayiannis, C. C., Ly, J., Singhal, S., Slater, L.-A., Kim, Y. D., Lee, K.-J., Lim, J.-S., Hara, H., Nishihara, M., Tanaka, J., Yoshikawa, M., Demirelli, D. S., Tanriverdi, Z., Uysal, E., Coutts, S. B., Chappell, F. M., Makin, S. D., Fung Mak, H. K., Teo, K. C., Wong, D. Y. K., Hert, L., Kubacka, M., Lyrer, P. A., Polymeris, A. A., Wagner, B., Zietz, A., Abrigo, J., Cheng, C., Chu, W. C., Leung, T. W., Seiffge, D. J., Fischer, U., Jung, S., Bos, D., Fluri, F., Phan, T. G., Srikanth, V. K., Heo, J. H., Bae, H.-J., Yakushiji, Y., Orken, D. N., Smith, E. E., Wardlaw, J. M., Kai Lau, G. K., Engelter, S. T., Peters, N., Soo, Y. O. Y., Song, T.-J., Simister, R. J., Wheeler, D. C. & Werring, D. J., 25 Aug 2026, In: Neurology. 107, 4, e218406.

      Research output: Contribution to journal › Article › Academic › peer-review

      Open Access
      File

    • Association of glomerular hyperfiltration with mortality in stroke: an analysis using pooled individual patient data

      Nash, P. S., Ambler, G., Best, J. G., Wilson, D., Du, H., Salman, R. A. S., Jäger, H. R., Lip, G. Y. H., Fandler-Höfler, S., Eppinger, S., Miwa, K., Shiozawa, M., Koga, M., Goeldlin, M. B., Beyeler, M., Bücke, P., El-Koussy, M., Mattle, H. P., Panos, L. D. & van Dam-Nolen, D. H. K. & 66 others, Dubost, F., Hendrikse, J., Kooi, M. E., Mess, W., Nederkoorn, P. J., Christ, N., Bellut, M., Gunkel, S., Karayiannis, C., Van Ly, J., Singhal, S., Slater, L. A., Kim, Y. D., Lee, K. J., Lim, J. S., Hara, H., Nishihara, M., Tanaka, J., Yoshikawa, M., Demirelli, D. S., Tanriverdi, Z., Bornstein, N. M., Molad, J., Assayag, E. B., Hallevi, H., Uysal, E., Coutts, S. B., Chappell, F., Makin, S., Mak, H., Teo, K. C., Wong, D. Y. K., Hert, L., Kubacka, M., Lyrer, P., Polymeris, A., Wagner, B., Zietz, A., Abrigo, J., Cheng, C., Chu, W., Leung, T. W. H., Seiffge, D., Fischer, U., Jung, S., Enzinger, C., Gattringer, T., Bos, D., Toyoda, K., Fluri, F., Phan, T., Srikanth, V., Heo, J. H., Bae, H. J., Yakushiji, Y., Orken, D. N., Smith, E. E., Wardlaw, J. M., Lau, G. K. K., Engelter, S. T., Peters, N., Soo, Y., Simister, R. J., Wheeler, D. C., Werring, D. J. & Song, T. J., May 2026, In: European Stroke Journal. 11, 5, aakag042.

      Research output: Contribution to journal › Article › Academic › peer-review

      Open Access
      File

    • Bi-allelic intermediate ATXN2 repeat expansions are associated with slow progressing, leg-onset familial ALS

      Demaegd, K. C., Koole, W., Van Vugt, J. J., Dankbaar, J. W., Hendrikse, J., Nazlı Başak, A., De Carvalho, M., Corcia, P., Codron, P., Bernard, E., Guissart, C., Couratier, P., Povedano Panades, M., Van Doorn, P. A., Warrenburg, B. P., Cooper-Knock, J., Pasterkamp, R. J., Van Rheenen, W., Van Damme, P. & Van den Berg, L. H. & 22 others, Veldink, J. H., Van Es, M. A., Vourc’h, P., Hardiman, O., McLaughin, R., Gotkine, M., Lerner, Y., Drory, V., Ticozzi, N., Silani, V., Salas, T., Jesus, S., Pardina, M., Andersen, P., Weber, M., Al-Chalabi, A., Shaw, C., Shaw, P. J., Morrison, K. E., Landers, J. E., Glass, J. D. & Dalgard, C. L., 18 Feb 2026, In: BMJ Neurology Open. 8, 1, e001417.

      Research output: Contribution to journal › Article › Academic › peer-review

      Open Access
      File
      1 Downloads (Pure)

    • Innate immune restoration after major surgery in the elderly: functional adaptation for maintaining immune reactivity

      BioCog consortium, 23 Jul 2026, In: The Innovation Medicine. 4, 3, 100223.

      Research output: Contribution to journal › Article › Academic › peer-review

      Open Access
      File
      2 Downloads (Pure)
    View all 397 research outputs
    • 2 Oral presentation
    • 1 Invited talk
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