Research output per year
Research output per year
Personal profile
Biography
Prof. Jeanette Leusen, received her PhD in 1995 at the University of Amsterdam, The Netherlands. She became associate professor and head of the immunotherapy group of the University Medical Center in Utrecht in 2006, and head of the UMAB facility in 2012. She has co-authored more than 150 publications in peer-reviewed journals and is inventor on 13 patent applications. Her group of 24 FTE works on the mechanism of action of therapeutic antibodies, with a special interest in IgA as a novel class of antibody for the treatment of both malignant as infectious disease.
Fellowship & awards
Dr Leusen holds several grants from Health Holland, KWF, Villa Joep! and industry.
Education/Academic qualification
PhD
1 Jun 1991 → 1 Dec 1995
Award Date: 13 Dec 1995
Keywords
- RM Therapeutics. Pharmacology
- Antibody therapy
- Fc receptors
- IgA
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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IgM Anti-Ganglioside Binding and Complement Activation in an iPSC-Derived Motor Neuron Model for Multifocal Motor Neuropathy
Krijgsman, D., Dijkxhoorn, K., de Zeeuw, E., Bloemenkamp, L. M., Bos, J. W., van Eijk, R. P. A., Van de Walle, I., Huizinga, R., Jacobs, B. C., Leusen, J. H. W., Pasterkamp, R. J., Hack, C. E., Budding, K. & van der Pol, W. L., 1 Jan 2026, In: Neurology(R) neuroimmunology & neuroinflammation. 13, 1, e200482.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Anti-PD-1 treatment response is associated with the influx of circulating myeloid and T-cell subsets into the metastatic melanoma tumor microenvironment
Van Dam, S., Krijgsman, D., Küçükköse, E., Verdonschot, M. E. L., Amini, M., Blokx, W. A. M., Van Eijs, M. J. M., Verheijden, R. J., Kranenburg, O., Suijkerbuijk, K. P. M., Leusen, J. H. W. & Vercoulen, Y., Nov 2025, In: British Journal of Cancer. 133, 9, p. 1250-1264 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Complement activation by IgM autoantibodies linked to immune-mediated neuropathies depends on C2
Budding, K., Dijkxhoorn, K., de Zeeuw, E., Bloemenkamp, L. M., van der Pol, W. L., Notermans, N. C., Minnema, M. C., Leusen, J. H. W., Hack, C. E. & Van de Walle, I., Jan 2025, In: European Journal of Neurology. 32, 1, e16541.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Downloads (Pure) -
Complementing CD20 antibodies’ effector functions
Leusen, J. & Valerius, T., 20 Mar 2025, In: Blood. 145, 12, p. 1232-1234 3 p.Research output: Contribution to journal › Editorial › Academic › peer-review
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Development and validation of a high throughput multiplex immunofluorescence assay to detect all human immunoglobulin isotypes and subclasses in human fluids
PRIMA Initiative Group, Apr 2025, In: Journal of immunology (Baltimore, Md. : 1950). 214, 4, p. 839–849 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Activities
- 3 Participation in conference
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Gordon Research Conference Antibody Biology and Engineering
Leusen, J. (Organiser)
13 Mar 2022 → 18 Mar 2022Activity: Participating in or organising an event › Participation in conference › Academic
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Faseb Scientific Research conference
Leusen, J. (Invited speaker)
15 Jun 2020Activity: Participating in or organising an event › Participation in conference › Academic
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Antibody Engineering and Therapeutics Europe
Leusen, J. (Keynote/plenary speaker) & Kuball, J. (Invited speaker)
10 Jun 2020 → 11 Jun 2020Activity: Participating in or organising an event › Participation in conference › Academic
Prizes
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Jeffrey Modell Foundation C.H.I.L.D.R.E.N! Research Program grant
Verhagen, L. (Recipient), Koenen, M. (Recipient), Boes, M. (Recipient), van Montfrans, J. (Recipient), Vastert, S. (Recipient), van Loosdregt, J. (Recipient) & Leusen, J. (Recipient), 2020
Prize: Fellowship awarded competitively