Personal profile
Personal webpage
Biography
Jacob M. van Laar is Professor at the Department of Rheumatology and Clinical Immunology at UMC Utrecht, the Netherlands. After obtaining his MD and PhD degrees at Leiden University, he specialised in Internal Medicine and Rheumatology in Leiden University Medical Center and worked at the Department of Rheumatology as clinical academic in various roles from 1997-2007, interrupted by a postdoctoral research fellowship at the National Institute of Arthritis and Musculoskeletal and Skin Diseases in Bethesda, USA. From 2007 until 2013 he held a Chair in Clinical Rheumatology at Newcastle University, and post as honorary consultant rheumatologist at The James Cook University Hospital, Middlesbrough, UK. He has been working as Professor of Rheumatology at UMC Utrecht since 1 November 2013. His main research interests involve clinical and pathogenetic aspects of systemic sclerosis and rheumatoid arthritis, aimed at improving the outcome of patients with rheumatic diseases by innovative clinical-translational research.
Fellowship & awards
Marie Parijs award for pioneering work in the field of clinical stem cell research in rheumatic autoimmune diseases (2002, Leiden University Medical Center)
ZonMW Clinical Fellow (2007)
Fellow of the Royal College of Physicians Edinburgh (2009)
NVLE Award (2015)
External positions
advisering en consultancies op het gebied van de reumatologie - 1. voorschrijver van medicatie, 2. verrichter van wetenschappelijk onderzoek - Adjuvantis (éénmanszaak)
18 Jul 2024 → 31 Dec 3999
reumatoloog - spreekuren als invaller - Artrose Instituut Nederland
18 Jul 2024 → 31 Dec 3999
Collaborations and top research areas from the last five years
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Tocilizumab vs prednisone in established rheumatoid arthritis patients (TOPIRA): an investigator-initiated randomized clinical trial
Fadaei, S., van der Leeuw, M. S., Linn-Rasker, S. P., de Klerk, B., Peeters, J. J. W., den Uyl, D., Maas-de Kok, A., Bos, R., Tekstra, J., Nap, F., Marijnissen, A. C. A., Welsing, P. M. J. & van Laar, J. M., 1 Feb 2026, In: Rheumatology (Oxford, England). 65, 2, keaf591.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
A composite biomarker score to predict modified Rodnan skin score in systemic sclerosis: insight from autologous stem cell transplantation international scleroderma trial
Rodolfi, S., Clark, K., Abdi, B. A., Roblin, E., Kanitkar, M., Ong, V. H., Voskuyl, A. E., De Vries-Bouwstra, J. K., van Laar, J. M., Denton, C. P. & Spierings, J., 10 Dec 2025, In: Arthritis research & therapy. 28, 1, 11.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Allogeneic stem cell transplantation in difficult-to-treat rheumatoid arthritis
Van Compernolle, K., Selleslag, D., Hazlewood, G. S., Storek, J., van Laar, J. M. & Piette, Y., 12 Mar 2025, In: Clinical and Experimental Rheumatology. 43, 3, p. 545 1 p.Research output: Contribution to journal › Letter › Academic › peer-review
Open AccessFile -
A phase 2 trial investigating the efficacy and safety of the mPGES-1 inhibitor vipoglanstat in systemic sclerosis-related Raynaud's
Tornling, G., Edenius, C., Pauling, J. D., Denton, C. P., Olsson, A., Kowalski, J., Murray, A., Anderson, M., Bhat, S., Del Galdo, F., Hall, F., Korkosz, M., Krasowska, D., Olas, J., Smith, V., Van Laar, J. M., Vonk, M. C., Wojteczek, A. & Herrick, A. L., 1 Feb 2025, In: Rheumatology. 64, 2, p. 704-713 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure) -
Dermal cellular senescence and EndMT in patients with systemic sclerosis undergoing cyclophosphamide or aHSCT treatment
Chiu, Y.-H., van Dijk, M., Goldschmeding, R., van Laar, J. M., de Vries-Bouwstra, J. K. & Spierings, J., 1 Jun 2025, In: Rheumatology (Oxford, England). 64, 6, p. 3957-3963 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Downloads (Pure)