Research output per year
Research output per year
Personal profile
Personal webpage
Biography
Gerard Pasterkamp, MD, is professor Experimental Cardiology and quarter maker of the Circulatory Health Research Center, UMC Utrecht. His research interests are in the field of cardiovascular biology and more specifically innovation in biomarkers. His research interests are in the field of cardiovascular biology and innovation in biomarkers and drug targets. The research group houses the largest atherosclerotic plaque biobank worldwide: Athero Express including >4000 patients. This biobank has generated new insights into determinants of plaque destabilisation. The laboratory also invests in the excavation of genetic determinants of atherosclerotic plaque characteristics. He coordinates national and EU based consortia with the aim to unravel biomarkers and mechanisms of atherosclerotic disease. His translational profile is noted in the private public consortia he is involved in. He is supervising three public private grants that have been rewarded with the aim to develop novel biomarkers and imaging technology to detect cardiac ischemia and endothelial dysfunction. In 2018 he obtained a LeDucq grant together with Prof G Owens (Virginia University) on the role of smooth muscle cell plasticity in the atherosclerotic plaque.
Side activities
Editorial scientific board ATVB, Cardiovascular research, Atherosclerosis, Eur J Cardiovascular Pharmacology
Board member of Dutch Atherosclerosis Society
Review board LS7 EU-ERC advanced grants and Finnish Academy of Sciences
External positions
reviewerspanel/commissie Health Holland ronde oktober 2024 - reviewen en met commissie belsuiten over honorering aanvragen - Health Holland
1 Sept 2024 → 31 Dec 3999
auteur - uitgeven van een boek, maar aantal uren is niet (meer) van toepassing. werk is al gedaan - persoonlijk, geen werkgever
12 Jan 2024 → 31 Dec 3999
Voorzitter Wetenschappelijke Adviesraad - Voorzitten vergaderingen - Reuma Nederland
1 Jul 2023 → 31 Dec 3999
Keywords
- Q Science (General)
- Vascular Biology, Atherosclerosis
- R Medicine (General)
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A critical appreciation of pathway analysis in atherosclerotic disease. Cellular phenotypic plasticity as an illustrative example
Wesseling, M., Diez-Benavente, E., Mokry, M., den Ruijter, H. M. & Pasterkamp, G., Mar 2024, In: Vascular Pharmacology. 154, p. 1-5 5 p., 107286.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure) -
Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans
Benavente, E. D., Hartman, R. J. G., Sakkers, T. R., Wesseling, M., Sloots, Y., Slenders, L., Boltjes, A., Mol, B. M., de Borst, G. J., de Kleijn, D. P. V., Prange, K. H. M., de Winther, M. P. J., Kuiper, J., Civelek, M., van der Laan, S. W., Horvath, S., Onland-Moret, C., Mokry, M., Pasterkamp, G. & den Ruijter, H. M., Jun 2024, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 44, 6, p. 1419-1431 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Downloads (Pure) -
CD163 + Macrophages Induce Endothelial-to-Mesenchymal Transition in Atheroma.
Mori, M., Sakamoto, A., Kawakami, R., Guo, L., Slenders, L., Mosquera, J. V., Ghosh, S. K. B., Wesseling, M., Shiraki, T., Bellissard, A., Shah, P., Weinkauf, C. C., Konishi, T., Sato, Y., Cornelissen, A., Kawai, K., Jinnouchi, H., Xu, W., Vozenilek, A. E. & Williams, D. & 15 others, , 5 Jul 2024, In: Circulation research. 135, 2, p. e4-e23Research output: Contribution to journal › Article › Academic › peer-review
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Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype
Rademakers, T., Manca, M., Jin, H., Orban, T., Perisic, L. M., Frissen, H. J. M., Rühle, F., Hautvast, P., van Rijssel, J., van Kuijk, K., Mees, B. M. E., Peutz-Kootstra, C. J., Heeneman, S., Daemen, M. J. A. P., Pasterkamp, G., Stoll, M., van Zandvoort, M. A. M. J., Hedin, U., Dequiedt, F. & van Buul, J. D. & 2 others, , Aug 2024, In: Angiogenesis. 27, 3, p. 461-474 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Identification of a gene network driving the attenuated response to lipopolysaccharide of monocytes from hypertensive coronary artery disease patients
Lu, C., Donners, M. M. P. C., de Baaij, J. B. J., Jin, H., Otten, J. J. T., Manca, M., van Zonneveld, A. J., Jukema, J. W., Kraaijeveld, A., Kuiper, J., Pasterkamp, G., Mees, B., Sluimer, J. C., Cavill, R., Karel, J. M. H., Goossens, P. & Biessen, E. A. L., 12 Feb 2024, In: Frontiers in Immunology. 15, 1286382.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure)
Activities
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ERC EU grant evaluations (Event)
Gerard Pasterkamp (Editor)
Nov 2017 → Nov 2023Activity: Publication peer-review and editorial work › Publication peer-review › Academic
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Arteriosclerosis (Journal)
Gerard Pasterkamp (Editor)
2004Activity: Publication peer-review and editorial work › Editorial activity › Academic
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American Journal of Cardiology (Journal)
Gerard Pasterkamp (Editor)
2004Activity: Publication peer-review and editorial work › Editorial activity › Academic
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Arteriosclerosis, Thrombosis and Vascular Biology (Journal)
Gerard Pasterkamp (Editor)
2004Activity: Publication peer-review and editorial work › Editorial activity › Academic
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Journal of the American College of Cardiology (Journal)
Gerard Pasterkamp (Editor)
2004Activity: Publication peer-review and editorial work › Editorial activity › Academic
Prizes
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Het navigatiesysteem van zenuwcellen
Pasterkamp, Gerard (Recipient), 2006
Prize: Prize (including medals and awards)