Emmanuel Wiertz
20072024

Research activity per year

Personal profile

Biography

Emmanuel Wiertz  obtained a degree in Veterinary Medicine from Utrecht University in 1986. From 1987-1994, he was investigator and group leader at the Vaccine Development Unit of the National Institute of Health and the Environment in Bilthoven, The Netherlands. In 1993, he obtained a PhD at Utrecht University for his studies on T cell recognition of Neisseria meningitidis outer membrane proteins (awarded cum laude). He received training in immunology, virology and cell biology as an intern at the Weizmann Institute of Science in Rehovot, Israel, and as EMBO fellow at the laboratory of Prof. Hidde Ploegh at MIT, Cambrigde MA (1994-1996). After returning from the US, he briefly went back to the RIVM and subsequently was appointed professor of Medical Microbiology, in particular Experimental Virology, at the Leiden University Medical Center. In 2009, his lab moved to the University Medical Center in Utrecht. The Wiertz lab investigates virus-host interactions, with special interest in viral immune evasion mechanisms. This research is at the interface of virology, immunology and cell biology, a combination of disciplines that has facilitated the elucidation of a variety of fascinating immune evasion strategies employed by herpesviruses. More recently, the lab has adopted novel technologies such as genome-wide shRNA libraries and the CRISPR/Cas technology as powerful instruments to explore new avenues in host-pathogen research.

Side activities

Chairman of the board of the Virology Division of the Royal Dutch Association for Microbiology (KNVM).

Member of the Dutch Society for Immunology (NVVI), the American Society for Microbiology (ASM) and the International Association for Research on Epstein-Barr virus and Associated Diseases.

Editor/Editorial board member of several scientific journals, and is a regular referee for national and international funding schemes.

Consultant to ORCA Therapeutics BV on the use of viruses (modified adenoviruses) in cancer therapy. Payments to UMC Utrecht. 

Fellowship & awards

(co-)awarded many fellowships and research grants in the course of his career. Among them are The Netherlands Organization for Scientific Research (NWO), the Dutch Cancer Society (KWF), several funding schemes of the European Commission, The Dr. F.P. Fischer Foundation, Dutch Diabetes Research Foundation (DFN), and Dutch Arthritis Foundation (DAF).

He is part of the European Horizon 2020 Consortium EDGE, a collaboration among academic, clinical and industrial partners addressing virological and immunological unknowns of herpesvirus infections.

 

 

Personal webpage

External positions

Voorzitter sectie virologie - expertise op het gebied van de virologie - KNVM

1 Jun 201631 Dec 3999

Keywords

  • QR355 Virology
  • Herpesviruses
  • Poxviruses
  • Antigen processing
  • Antiviral Immunity
  • Immune Evasion

Collaborations and top research areas from the last five years

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