Research output per year
Research output per year
Personal profile
Biography
Edwin Cuppen is initiator and scientific director of the Hartwig Medical Foundation (part-time since 2015 and full time since 2021), a not-for-profit organisation that aims to improve cancer care by systematic whole genome sequencing analysis of tumors and that also maintains one of the world’s largest databases of cancer whole genome sequencing data enriched with clinical patient data. After his undergraduate and PhD training at Wageningen University and Radboud University Nijmegen as a molecular geneticist, he held research and group leader positions at the Netherlands Cancer Institute, the Hubrecht Institute and the UMC Utrecht. His expertise is in cancer genomics and functional genetics.
Fellowship & awards
European Young Investigator Award 2005
NWO Vici grant 2013
External positions
Consultant - Consultancy - AlphaSights
1 Jan 2025 → 31 Dec 2025
Consultant - Consultancy - Healthcare Equities Gerson Lehrman Group
1 Jan 2025 → 31 Dec 2025
Adviseur - Advies - Roche
1 Jan 2025 → 31 Dec 2025
Spreker - Houden van lezingen - Spreker bij diverse organisaties
1 Jul 2024 → 31 Dec 3999
Scientific Director - overeenkomstig researchgebied - Hartwig Medical Foundation
1 Jan 2016 → 31 Dec 3999
Advisering - Raakvlakken met onderzoeksveld - Scientific Advisory Board InteRNA Technologies BV (miRNA-b
1 Jan 2013 → 31 Dec 3999
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Clinical implications of whole genome sequencing in metastatic colorectal cancer
Smabers, L. P., Nienhuis, H. H., de Leng, W. W. J., Roepman, P., Ciftcibasi, I. Ö. A., Wensink, G. E., Huismans, M. A., Valkenburg-van Iersel, L. B. J., Cirkel, G. A., Gootjes, E. C., Verheul, H. M. W., Jeurissen, F. J., Bol, G. M., Kranenburg, O., Koopman, M., Cuppen, E. & Roodhart, J. M. L., 15 Dec 2025, In: Oncogene. 44, 48, p. 4686-4698 13 p.Research output: Contribution to journal › Article › Academic › peer-review
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Genomic distinctions in adolescent and young adult cancer: A comprehensive review
van Putten, J., Lankhorst, L. H., de Langen, A. J., van der Wekken, A. J., Roodhart, J., Bolhuis, K., Oosting, S. F., van Dongen, M., Kok, M., Geurts, M., Koekkoek, J. A. F., Cuppen, E., Nienhuis, H. H. & van der Graaf, W. T. A., Nov 2025, In: Cancer Treatment Reviews. 140, 12 p., 103021.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Downloads (Pure) -
Patient-derived organoids predict treatment response in metastatic colorectal cancer
Smabers, L. P., Wensink, G. E., Verissimo, C. S., Doorn, M., Yang, T., Voskuilen, T., Huismans, M. A., Valkenburg-van Iersel, L., Cirkel, G. A., Gootjes, E. C., Verheul, H. M. W., Jeurissen, F. J., Bol, G. M., Nienhuis, H. H., Braat, M. N. G. J. A., Cuppen, E., Vries, R. G. J., van der Baan, F. H., Elias, S. G. & Kranenburg, O. & 3 others, , 2025, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 31, 23, p. 5015–5026Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Whole genome sequencing-based analysis of genetic predisposition to adult glioblastoma
van Opijnen, M. P., van Valkengoed, D. R., de Ligt, J., de Vos, F. Y. F., Broekman, M. L. D., Cuppen, E. & Koster, R., 30 Oct 2025, In: npj Genomic Medicine. 10, 1, 11 p., 70.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications
Vis, D. J., Palit, S. A. L., Corradi, M., Cuppen, E., Mehra, N., Lolkema, M. P., Wessels, L. F. A., van der Heijden, M. S., Zwart, W. & Bergman, A. M., 20 Mar 2025, In: Genome Medicine. 17, 1, 13 p., 24.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Downloads (Pure)
Activities
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Multilevel effects of non-coding genetic variation on regulatory elements and chromatin organization
Cuppen, E. (Speaker)
1 Dec 2014Activity: Talk or presentation › Oral presentation › Academic
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4 daags congres over Rat Genomics (Hinxton, Engeland)
Cuppen, E. (Organiser)
1 Dec 2014 → 4 Dec 2014Activity: Participating in or organising an event › Participation in conference › Academic
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Toekomst van genetische diagnostiek
Cuppen, E. (Speaker)
20 Nov 2014Activity: Talk or presentation › Oral presentation › Academic
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Voorzitten parallel programma tijdens CHAINS (Veldhoven)
Cuppen, E. (Organiser)
18 Nov 2014Activity: Participating in or organising an event › Participation in conference › Academic
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CGC meeting (Amsterdam)
Cuppen, E. (Participant)
14 Nov 2014Activity: Participating in or organising an event › Participation in conference › Academic
Press/Media
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in programma 'met het oog op morgen'
3/07/10
1 Media contribution
Press/Media: Public Engagement Activities