Research output per year
Research output per year
Personal profile
Biography
Edwin Cuppen is initiator and scientific director of the Hartwig Medical Foundation (part-time since 2015 and full time since 2021), a not-for-profit organisation that aims to improve cancer care by systematic whole genome sequencing analysis of tumors and that also maintains one of the world’s largest databases of cancer whole genome sequencing data enriched with clinical patient data. After his undergraduate and PhD training at Wageningen University and Radboud University Nijmegen as a molecular geneticist, he held research and group leader positions at the Netherlands Cancer Institute, the Hubrecht Institute and the UMC Utrecht. His expertise is in cancer genomics and functional genetics.
Side activities
Academic advisory activities
Scientific Advisory Board InteRNA Technologies BV (2006-2023) (miRNA-based therapeutics) (personal remuneration)
Advisory Board Clinical Whole Genome Sequencing Illumina (2019-2023) (remuneration transfered to employer)
Employment at other organisation
Full time Scientific Director Hartwig Medical Foundation
Minimal appointment at UMC Utrecht
Fellowship & awards
European Young Investigator Award 2005
NWO Vici grant 2013
External positions
Committee member - Selection Board Committee for a Group Leader & Professor position in cancer systems biomedicine - Institute of Cancer Research (ICR), Oslo University Hospit
1 Feb 2025 → 30 Apr 2025
Spreker - Houden van lezingen - Spreker bij diverse organisaties
1 Jul 2024 → 31 Dec 3999
Advies - Researchgebied - Advisory Board Clinical Whole Genome Sequencing Illumina
1 Jan 2019 → 31 Dec 3999
Scientific Director - overeenkomstig researchgebied - Hartwig Medical Foundation
1 Jan 2016 → 31 Dec 3999
Advisering - Raakvlakken met onderzoeksveld - Scientific Advisory Board InteRNA Technologies BV (miRNA-b
1 Jan 2013 → 31 Dec 3999
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A pan-cancer analysis of the microbiome in metastatic cancer
Battaglia, T. W., Mimpen, I. L., Traets, J. J. H., van Hoeck, A., Zeverijn, L. J., Geurts, B. S., de Wit, G. F., Noë, M., Hofland, I., Vos, J. L., Cornelissen, S., Alkemade, M., Broeks, A., Zuur, C. L., Cuppen, E., Wessels, L., van de Haar, J. & Voest, E., 25 Apr 2024, In: Cell. 187, 9, p. 2324-2335.e19Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Combining Genomic Biomarkers to Guide Immunotherapy in Non-Small Cell Lung Cancer
Van De Haar, J., Mankor, J. M., Hummelink, K., Monkhorst, K., Smit, E. F., Wessels, L. F. A., Cuppen, E., Aerts, J. G. J. V. & Voest, E. E., 1 Apr 2024, In: Clinical Cancer Research. 30, 7, p. 1307-1318 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
EXO1 protects BRCA1-deficient cells against toxic DNA lesions
van de Kooij, B., Schreuder, A., Pavani, R., Garzero, V., Uruci, S., Wendel, T. J., van Hoeck, A., San Martin Alonso, M., Everts, M., Koerse, D., Callen, E., Boom, J., Mei, H., Cuppen, E., Luijsterburg, M. S., van Vugt, M. A. T. M., Nussenzweig, A., van Attikum, H. & Noordermeer, S. M., 15 Feb 2024, In: Molecular Cell. 84, 4, p. 659-674.e7Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Five latent factors underlie response to immunotherapy
Usset, J., Rosendahl Huber, A., Andrianova, M. A., Batlle, E., Carles, J., Cuppen, E., Elez, E., Felip, E., Gómez-Rey, M., Lo Giacco, D., Martinez-Jimenez, F., Muñoz-Couselo, E., Siu, L. L., Tabernero, J., Vivancos, A., Muiños, F., Gonzalez-Perez, A. & Lopez-Bigas, N., Oct 2024, In: Nature genetics. 56, 10, p. 2112-2120 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Impact of genetic counseling strategy on diagnostic yield and workload for genome-sequencing-based tumor diagnostics
Koster, R., Schipper, L. J., Giesbertz, N. A. A., van Beek, D., Mendeville, M., Samsom, K. G., Rosenberg, E. H., Hogervorst, F. B. L., Roepman, P., Boelens, M. C., Bosch, L. J. W., van den Berg, J. G., Meijer, G. A., Voest, E. E., Cuppen, E., Ruijs, M. W. G., van Wezel, T., van der Kolk, L. & Monkhorst, K., Feb 2024, In: Genetics in medicine : official journal of the American College of Medical Genetics. 26, 2, 13 p., 101032.Research output: Contribution to journal › Article › Academic › peer-review
Activities
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4 daags congres over Rat Genomics (Hinxton, Engeland)
Cuppen, E. (Organiser)
1 Dec 2014 → 4 Dec 2014Activity: Participating in or organising an event › Participation in conference › Academic
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Multilevel effects of non-coding genetic variation on regulatory elements and chromatin organization
Cuppen, E. (Speaker)
1 Dec 2014Activity: Talk or presentation › Oral presentation › Academic
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Toekomst van genetische diagnostiek
Cuppen, E. (Speaker)
20 Nov 2014Activity: Talk or presentation › Oral presentation › Academic
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Voorzitten parallel programma tijdens CHAINS (Veldhoven)
Cuppen, E. (Organiser)
18 Nov 2014Activity: Participating in or organising an event › Participation in conference › Academic
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CGC meeting (Amsterdam)
Cuppen, E. (Participant)
14 Nov 2014Activity: Participating in or organising an event › Participation in conference › Academic
Press/Media
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in programma 'met het oog op morgen'
3/07/10
1 Media contribution
Press/Media: Public Engagement Activities