Edward Knol

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Edward Knol

dr.

 https://orcid.org/0000-0001-7368-9820
    1988 …2025

    Research activity per year

    Personal profile

    Biography

    Edward Knol is a biomedical scientist and immunologist in the departments of Immunology and Dermatology/Allergology at the University Medical Center Utrecht. He did his PhD training in the Blood Transfusion Service of the University of Amsterdam and had a postdoc position at Johns Hopkins University in Baltimore. His scientific research focuses on allergic diseases, in particularly eczema and food allergy. The research focusses on 1) improved insights in pathomechanisms, 2) explore new treatment options, 3) improve current diagnostics and establish new diagnostics platforms. In his career Edward Knol discovered CD63 as the basophil activation marker, described the important role of the peanut allergen Ara h 2 and described A20/TNFAIP3 dysregulation in atopic dermatitis. He is involved in several (inter)national collaborations and is Secretary General of the Dutch Society of Immunology (~1400 members).

    Within the University Medical Center he holds a teaching position and chairs the education committee of the University Utrecht graduate school Immunity and Infection (50 master and 170 PhD students). He is coordinator and examiner of: 1) Course Clinical Immunology for 3rd years students Biomedical Sciences, 2) Course Immune Therapy for 2nd years student Medicine and 3) Course Infection and Immunity for 3rd years Students at the Technical University Eindhoven. 

    At the international level Edward Knol has organised 3 European Academy of Allergy and Clinical Immunology (EAACI) Winter schools and was the chair of the Scientific Program Committee of the EAACI annual meetings in 2014-2016. In addition, since 2019 he is Vice President Congresses of EAACI. 

    Specialties: Immunology, Allergy, Food Allergy, Atopic Dermatitis, Basophilic granulocytes, T lymphocytes, allergy diagnostic tests, basophil activation test

    Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=Knol%20EF%5BAuthor%5D&cauthor=true&cauthor_uid=26198455

     

    Google Scholar:  http://scholar.google.com/citations?hl=en&user=nfo_25cAAAAJ

    Scopus H-factor: h-index: 51

    Research gate: h-index: 54, : RG score: 46,95

    Google Scholar: h-index: 60 

     

    Side activities

    2009- Chair Educational committee Master and PhD program Graduate School Immunity and Infection, University van Utrecht. Supervising the training program of 50 Master students and 180 PhD students.

    2013- Co-director FOCIS Center of Excellence, Utrecht Infection and Immunity Center.

    2014- Member taskforce IgE diagnostics, EAACI

    2015- Member guideline committee Allergy Immunotherapy, EAACI

    2015-2018 Steering committee member FOCIS, representing EAACI

    2014-2016 Chair Scientific Program Committee (SPC) EAACI, coordinating EAACI annual meetings in 2015 (Barcelona) and 2016 (Vienna).

    2019- Vice President EAACI Congresses and Events, coordinating all scientific meetings of European Academy of Allergy and Clinical Immunology ranging from 8500 participants to 280 participants per meeting

     

    Editorial Board memberships:

    - Dutch Journal for Allergology

    - Clinical and Translational Allergy

    - Clinical and Experimental Allergy

     

     

     

    Collaborations and top research areas from the last five years

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    • EAACI guidelines on the management of IgE-mediated food allergy

      Santos, A. F., Riggioni, C., Agache, I., Akdis, C. A., Akdis, M., Alvarez-Perea, A., Alvaro-Lozano, M., Ballmer-Weber, B., Barni, S., Beyer, K., Bindslev-Jensen, C., Brough, H. A., Buyuktiryaki, B., Chu, D., Del Giacco, S., Dunn-Galvin, A., Eberlein, B., Ebisawa, M., Eigenmann, P. & Eiwegger, T. & 44 others, Feeney, M., Fernandez-Rivas, M., Fiocchi, A., Fisher, H. R., Fleischer, D. M., Giovannini, M., Gray, C., Hoffmann-Sommergruber, K., Halken, S., O'B Hourihane, J., Jones, C. J., Jutel, M., Knol, E. F., Konstantinou, G. N., Lack, G., Lau, S., Mejias, A. M., Marchisotto, M. J., Meyer, R., Mortz, C. G., Moya, B., Muraro, A., Nilsson, C., de Oliveira, L. C. L., O'Mahony, L., Papadopoulos, N. G., Perrett, K. P., Peters, R., Podesta, M., Poulsen, L. K., Roberts, G., Sampson, H., Schwarze, J., Smith, P., Tham, E., Untersmayr, E., Van Ree, R., Venter, C., Vickery, B., Vlieg-Boerstra, B., Werfel, T., Worm, M., Du Toit, G. & Skypala, I., Jan 2025, In: Allergy. 80, 1, p. 14-36 23 p.

      Research output: Contribution to journal › Article › Academic › peer-review

      Open Access
      File

    • Towards a common approach for managing food allergy and serious allergic reactions (anaphylaxis) at school. GA2LEN and EFA consensus statement

      Deschildre, A., Alvaro-Lozano, M., Muraro, A., Podesta, M., de Silva, D., Giovannini, M., Barni, S., Dribin, T. E., Sandoval-Ruballos, M., Anagnostou, A., Fiocchi, A., Toniolo, A., Bird, A., Sanz, A. S., Asarnoj, A., Nowak-Wegrzyn, A., Vlieg-Boerstra, B., Vickery, B. P., Venter, C. & Nilsson, C. & 61 others, Parente, C., Demoulin, C., Fleischer, D. M., Bijlhout, D., Knol, E. F., Garrow, E., Cook, E. E., Schultz, F., Lazzarotto, F., Mori, F., Wong, G., Lack, G., Roberts, G., Marino, G. A., Elberink, H. N. G. O., Brough, H. A., Sampson, H. A., Lieberman, J., Gerdts, J., Zhao, J., Gradman, J., Upton, J. E. M., Wang, J., Palosuo, K., Järvinen, K. M., Beyer, K., Shen, K., Polloni, L., Mandelbaum, L., Tanno, L. K., Bilaver, L. A., Shaker, M. S., Worm, M., Said, M., Kelly, M., Marchisotto, M. J., Makris, M., Odemyr, M., Fernandez-Rivas, M., Ebisawa, M., Patel, N., Rodríguez del Río, P., Vichyanond, P., Turner, P., Smith, P., Gaspar, P. M., Chinthrajah, R. S., Rachid, R., Bonaguro, R., Gupta, R., Schnadt, S., Sato, S., Arasi, S., Leonard, S., Poblete, S., Halken, S., Le, T. M., Pouessel, G., Dunn, T., Cardona, V. & Zuberbier, T., Jan 2025, In: Clinical and Translational Allergy. 15, 1, e70013.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      File

    • Traduction et republication de « Recommandations de l’EAACI sur le diagnostic de l’allergie alimentaire médiée par les IgE »

      Translated title of the contribution: Translation into French and republication of “EAACI guidelines on the diagnosis of IgE-mediated food allergy”Santos, A. F., Riggioni, C., Agache, I., Akdis, C. A., Akdis, M., Alvarez-Perea, A., Alvaro-Lozano, M., Ballmer-Weber, B., Barni, S., Beyer, K., Bindslev-Jensen, C., Brough, H. A., Buyuktiryaki, B., Chu, D., Del Giacco, S., Dunn-Galvin, A., Eberlein, B., Ebisawa, M., Eigenmann, P. & Eiwegger, T. & 43 others, Feeney, M., Fernandez-Rivas, M., Fisher, H. R., Fleischer, D. M., Giovannini, M., Gray, C., Hoffmann-Sommergruber, K., Halken, S., O'B Hourihane, J., Jones, C. J., Jutel, M., Knol, E., Konstantinou, G. N., Lack, G., Lau, S., Marques Mejias, A., Marchisotto, M. J., Meyer, R., Mortz, C. G., Moya, B., Muraro, A., Nilsson, C., Camargo Lopes de Oliveira, L., O'Mahony, L., Papadopoulos, N. G., Perrett, K., Peters, R. L., Podesta, M., Poulsen, L. K., Roberts, G., Sampson, H. A., Schwarze, J., Smith, P., Huiwen Tham, E., Untersmayr, E., Van Ree, R., Venter, C., Vickery, B. P., Vlieg-Boerstra, B., Werfel, T., Worm, M., Du Toit, G. & Skypala, I., Jan 2025, In: Revue Francaise d'Allergologie. 65, 1, 104181.

      Research output: Contribution to journal › Article › Academic › peer-review

    • Type 2 Immune-Dominant Endotype Is Not Associated With Increased Responsiveness to Dupilumab Treatment in Adult Atopic Dermatitis Patients

      Dekkers, C., Smits, H., Stölzl, D., Spekhorst, L., Knol, E., van Wijk, F., Harder, I., Werfel, T., Schmitt, J., Kleinheinz, A., Abraham, S., Thijs, J., Weidinger, S., de Bruin-Weller, M., Bakker, D. & Drylewicz, J., Jan 2025, In: Clinical and Experimental Allergy. 55, 1, p. 97-99 3 p.

      Research output: Contribution to journal › Letter › Academic › peer-review

      Open Access
      File
      2 Downloads (Pure)

    • 10 practical priorities to prevent and manage serious allergic reactions: GA2LEN ANACare and EFA Anaphylaxis Manifesto

      Muraro, A., de Silva, D., Podesta, M., Anagnostou, A., Cardona, V., Halken, S., Smith, P., Tanno, L. K., Turner, P., Worm, M., Alvaro-Lozano, M., Arasi, S., Asarnoj, A., Barni, S., Beyer, K., Bilaver, L. A., Bird, A., Bonaguro, R., Brough, H. A. & Chinthrajah, R. S. & 31 others, Cook, E. E., Demoulin, C., Deschildre, A., Dribin, T. E., Ebisawa, M., Fernandez-Rivas, M., Fiocchi, A., Fleischer, D. M., Garrow, E., Gerdts, J., Giovannini, M., Järvinen, K. M., Kelly, M., Knol, E. F., Lack, G., Lazzarotto, F., Le, T.-M., Leonard, S., Lieberman, J., Makris, M., Mandelbaum, L., Marchisotto, M. J., Marino, G. A., Mori, F., Nilsson, C., Nowak-Wegrzyn, A., Odemyr, M., Oude Elberink, H. N. G., Palosuo, K., Patel, N., Dec 2024, In: Clinical and Translational Allergy. 14, 12, e70009.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      File
      2 Downloads (Pure)
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