Eric Spierings

Eric Spierings public CV

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Research activity per year

Personal webpage

http://www.tumor-immunology-utrecht.nl/eric-spierings

Personal webpage

http://nl.linkedin.com/ericspierings/

Biography

Dr. Spierings received his PhD degree as immunologist at the Leiden University Medical Center, The Netherlands and was subsequently recognized as SMBWO Immunologist by the Dutch Society for Immunology. His postdoctoral training was performed on minor H antigens in organ- and stem-cell transplantation in the laboratory of Prof. Dr. Els Goulmy, Leiden, The Netherlands. In 2008, he was appointed as lab director of the HLA laboratory of the University Medical Centre Utrecht, The Netherlands. In that position, he combines diagnostic histocompatibility testing with research. His current scientific interest focusses on the role of indirect recognition of mismatched HLA in transplantation and on post-transplant immunomonitoring via Next Generation Sequencing of T- and B-cell receptors and immunoglobulins.

Side activities

Associate editor: Frontiers in Immunology ( Section Alloimmunity and Transplantation)
Editorial Board: HLA
Editorial board: Cellular Immunology
Co-chair for the 18th International HLA & Immunogenetics Workshop (ihiw18.org)
Co-chair for the 35th Conference of the European Federation for Immunogenetics
Chair of the Bio-informatics Committee of the European Federation for Immunogenetics
Member of the Scientific Committee of the European Federation for Immunogenetics
Head of the Matchis Expertise Center, Leiden, The Netherlands
President of the International HLA & Immunogenetics Workshop

Fellowship & awards

1997: KNAW van Walree Grant
2002: Best Abstract Award – 13th International Histocompatibility Workshop Conference
2004: Special Fellow – Leukemia and Lymphoma Society
2007: Best Abstract Award – European Federation for Immunogenetics Conference
2009: Best Abstract Award – European Federation for Immunogenetics Conference
2013: Ureka Mega Challenge Award for Innovation – UMC Utrecht
2016: Novartis Award for best scientific publication – Dutch Transplantation Society
2017: Medical Immunology Science Award – Dutch Society for Immunology

External positions

Member of the Scientific Committee - Member of the Scientific Committee - European Federation for Immunogenetics

21 May 2024 → 31 Dec 3999

Co-president - HLA, transplantation, and immunogenetics - International HLA & Immunogenetics Workshop Council

14 May 2022 → 31 Dec 3999

Contract Research - Onderzoek naar T cel en B cel epitopen en verfijnen van bestaande algoritmes - PIRCHE AG

1 Jan 2022 → 31 Dec 3999

Medisch Immunoloog Kenniscentrum MATCHIS. Consultverlening in het kader van stamceltransplantatie. - Histocompatibiliteit in stamceltransplantatie. Complementair en niet competerend. - Stichting MATCHIS

25 Jun 2020 → 31 Dec 3999

Member of the Editorial Board - Member of the Editorial Board - HLA Immune Response Genetics

1 Jan 2019 → 31 Dec 3999

Chair of the IT and Bioinformatics Committee - HLA and automation - European Federation for Immunogenetics

1 May 2018 → 31 Dec 3999

Chair of the Bioinformatics and IT Committee - Chair of the Bioinformatics and IT Committee - European Federation for Immunogenetics

1 May 2018 → 31 Dec 3999

Chair and Treasurer - HLA, transplantation, and Immunogenetics - 18th International HLA&Immunogenetics Workshop Foundation

31 Dec 2017 → 31 Dec 3999

Associate Editor - Associate Editor - Frontiers in Immunology

1 Jul 2016 → 31 Dec 3999

Member of the Editorial Board - Member of the Editorial Board - Cellular Immunology

1 Jan 2015 → 31 Dec 3999

Contract Research and advisory function - HLA matching at the epitope level - PIRCHE AG

3 Jan 2014 → 31 Dec 3999

113 Article
8 Meeting Abstract
4 Review article
2 Chapter
More

The number of donor HLA-derived T cell epitopes available for indirect antigen presentation determines the risk for vascular rejection after kidney transplantation
Betjes, M. G. H., Peereboom, E. T. M., Otten, H. G. & Spierings, E., 30 Aug 2022, In: Frontiers in Immunology. 13, 973968.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
12 Downloads (Pure)
T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation
Peereboom, E. T. M., Matern, B. M., Tomosugi, T., Niemann, M., Drylewicz, J., Joosten, I., Allebes, W. A., van der Meer, A., Hilbrands, L. B., Baas, M. C., van Reekum, F. E., Verhaar, M. C., Kamburova, E. G., Seelen, M. A. J., Sanders, J. S., Hepkema, B. G., Lambeck, A. J., Bungener, L. B., Roozendaal, C. & Tilanus, M. G. J. & 24 others, Voorter, C. E., Wieten, L., van Duijnhoven, E. M., Gelens, M. A. C. J., Christiaans, M. H. L., van Ittersum, F. J., Nurmohamed, A., Lardy, N. M., Swelsen, W., van der Pant, K. A., van der Weerd, N. C., Ten Berge, I. J. M., Bemelman, F. J., de Vries, A. P. J., de Fijter, J. W., Betjes, M. G. H., Roelen, D. L., Claas, F. H., Otten, H. G., Heidt, S., van Zuilen, A. D., Kobayashi, T., Geneugelijk, K. & Spierings, E., 18 Nov 2021, In: Frontiers in Immunology. 12, p. 1-13 784040.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
PIRCHE-II is related to graft failure after kidney transplantation
Geneugelijk, K., Niemann, M., Drylewicz, J., van Zuilen, A. D., Joosten, I., Allebes, W. A., van der Meer, A., Hilbrands, L. B., Baas, M. C., Erik Hack, C., van Reekum, F. E., Verhaar, M. C., Kamburova, E. G., Bots, M. L., Seelen, M. A. J., Sanders, J. S., Hepkema, B. G., Lambeck, A. J., Bungener, L. B. & Roozendaal, C. & 24 others, Tilanus, M. G. J., Vanderlocht, J., Voorter, C. E., Wieten, L., van Duijnhoven, E. M., Gelens, M., Christiaans, M. H. L., van Ittersum, F. J., Nurmohamed, A., Lardy, J. N. M., Swelsen, W., van der Pant, K. A., van der Weerd, N. C., ten Berge, I. J. M., Bemelman, F. J., Hoitsma, A., van der Boog, P. J. M., de Fijter, J. W., Betjes, M. G. H., Heidt, S., Roelen, D. L., Claas, F. H., Otten, H. G. & Spierings, E., 5 Mar 2018, In: Frontiers in Immunology. 9, MAR, 321.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
Computational Eurotransplant kidney allocation simulations demonstrate the feasibility and benefit of T-cell epitope matching
Niemann, M., Lachmann, N., Geneugelijk, K. & Spierings, E., Jul 2021, In: PLoS Computational Biology. 17, 7, p. 1-22 e1009248.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
1 Downloads (Pure)
Determination of the clinical relevance of donor epitope-specific HLA-antibodies in kidney transplantation
Kardol-Hoefnagel, T., Senejohnny, D. M., Kamburova, E. G., Wisse, B. W., Reteig, L., Gruijters, M. L., Joosten, I., Allebes, W. A., van der Meer, A., Hilbrands, L. B., Baas, M. C., Spierings, E., Hack, C. E., van Reekum, F. E., van Zuilen, A. D., Verhaar, M. C., Bots, M. L., Drop, A. C. A. D., Plaisier, L. & Melchers, R. C. A. & 30 others, Seelen, M. A. J., Sanders, J. S., Hepkema, B. G., Lambeck, A. J. A., Bungener, L. B., Roozendaal, C., Tilanus, M. G. J., Voorter, C. E., Wieten, L., van Duijnhoven, E. M., Gelens, M. A. C. J., Christiaans, M. H. L., van Ittersum, F. J., Nurmohamed, S. A., Lardy, N. M., Swelsen, W., van der Pant, K. A. M. I., van der Weerd, N. C., Ten Berge, I. J. M., Hoitsma, A., van der Boog, P. J. M., de Fijter, J. W., Betjes, M. G. H., Roelen, D. L., Claas, F. H., Bemelman, F. J., Senev, A., Naesens, M., Heidt, S. & Otten, H. G., Jan 2024, In: HLA. 103, 1, e15346.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
3 Downloads (Pure)

22 Invited talk
2 Membership of board
1 Participation in conference
1 Participation in workshop, seminar, course

Vergeet Tinder, neem HLA: De perfecte (mis)match
Eric Spierings (Speaker)
11 Nov 2022
Activity: Talk or presentation › Invited talk › Academic
PIRCHE : past present and future
Eric Spierings (Speaker)
25 Oct 2022
Activity: Talk or presentation › Invited talk › Academic
T-cell epitopes in transplantation
Eric Spierings (Speaker)
23 Sept 2019
Activity: Talk or presentation › Invited talk › Academic
Vergeet Tinder, neem HLA: De perfecte (mis)match
E Spierings (Speaker)
10 Nov 2023
Activity: Talk or presentation › Invited talk › Academic
HLA epitopen: de sleutel tot de juiste HLA (mis)match
E Spierings (Speaker)
14 Oct 2023
Activity: Talk or presentation › Invited talk › Popular

Medical Immunology Science Award
Spierings, Eric (Recipient), 14 Dec 2017
Prize: Prize (including medals and awards)

Eric Spierings

Personal profile

Personal webpage

Personal webpage

Biography

Side activities

Fellowship & awards

External positions

Collaborations and top research areas from the last five years

Dive into details

The number of donor HLA-derived T cell epitopes available for indirect antigen presentation determines the risk for vascular rejection after kidney transplantation

T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation

PIRCHE-II is related to graft failure after kidney transplantation

Computational Eurotransplant kidney allocation simulations demonstrate the feasibility and benefit of T-cell epitope matching

Determination of the clinical relevance of donor epitope-specific HLA-antibodies in kidney transplantation

Vergeet Tinder, neem HLA: De perfecte (mis)match

PIRCHE : past present and future

T-cell epitopes in transplantation

Vergeet Tinder, neem HLA: De perfecte (mis)match

HLA epitopen: de sleutel tot de juiste HLA (mis)match

Medical Immunology Science Award

Eric Spierings

Personal profile

Personal webpage

Personal webpage

Biography

Side activities

Fellowship & awards

External positions

Collaborations and top research areas from the last five years

Research output

Activities

Prizes