Alwin Huitema

2025

Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices

Schouten, W. M., Van Bocxlaer, K., Rosing, H., Huitema, A. D. R., Beijnen, J. H., Kratz, J. M., Mowbray, C. E. & Dorlo, T. P. C., 1 Jan 2025, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1250, 124377.

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2024

Adherence to low-dose methotrexate in children with juvenile idiopathic arthritis using a sensitive methotrexate assay

Möhlmann, J. E., de Roock, S., Egas, A. C., Weijden, E. T., Doeleman, M. J. H., Huitema, A. D. R., van Luin, M. & Swart, J. F., 7 May 2024, In: Pediatric rheumatology online journal. 22, 1, 52.

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A joint model of longitudinal pharmacokinetic and time-to-event data to study exposure-response relationships: a proof-of-concept study with alectinib

Lin, L., van der Noort, V., Steeghs, N., Ruiter, G., Beijnen, J. H. & Huitema, A. D. R., Sept 2024, In: Cancer Chemotherapy and Pharmacology. 94, 3, p. 453-459 7 p.

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A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum

Buitelaar, P. L. M., de Jong, K. A. M., Aardenburg, L., van der Heijden, M. S., Huitema, A. D. R., Beijnen, J. H. & Rosing, H., 15 Jun 2024, In: Journal of Pharmaceutical and Biomedical Analysis. 243, 9 p., 116108.

Research output: Contribution to journal › Article › Academic › peer-review

Analytical Validation of a Volumetric Absorptive Microsampling Method for Therapeutic Drug Monitoring of the Oral Targeted Anticancer Agents, Abiraterone, Alectinib, Cabozantinib, Imatinib, Olaparib, and Sunitinib, and Metabolites

Meertens, M., de Vries, N., Rosing, H., Steeghs, N., Beijnen, J. H. & Huitema, A. D. R., Aug 2024, In: Therapeutic drug monitoring. 46, 4, p. 494-502 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

A proof-of-concept study of sequential treatment with the HDAC inhibitor vorinostat following BRAF and MEK inhibitors in BRAFV600mutated melanoma

Embaby, A., Huijberts, S. C. F. A., Wang, L., Leite de Oliveira, R., Rosing, H., Nuijen, B., Sanders, J., Hofland, I., van Steenis, C., Kluin, R. J. C., Lieftink, C., Smith, C. G., Blank, C. U., van Thienen, J. V., Haanen, J. B. A. G., Steeghs, N., Opdam, F. L., Beijnen, J. H., Huitema, A. D. R. & Bernards, R. & 2 others, Schellens, J. H. M. & Wilgenhof, S., 1 Aug 2024, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 30, 15, p. 3157-3166 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Are novel oral oncolytics underdosed in obese patients?

Lin, L., van der Meer, E. K. O., Steeghs, N., Beijnen, J. H. & Huitema, A. D. R., Feb 2024, In: Cancer Chemotherapy and Pharmacology. 93, 2, p. 129-136 8 p.

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Automated radiolabelling of [⁶⁸Ga]Ga-PSMA-11 (gallium (⁶⁸Ga)-gozetotide) using the Locametz® kit and two generators

van Brandwijk, E. A., Aalbersberg, E. A., Hosseini, A. S., Huitema, A. D. R. & Hendrikx, J. J. M. A., 17 Apr 2024, In: EJNMMI Radiopharmacy and Chemistry. 9, 1, 12 p., 31.

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Bosutinib in Resistant and Intolerant Pediatric Patients With Chronic Phase Chronic Myeloid Leukemia: Results From the Phase I Part of Study ITCC054/COG AAML1921

Brivio, E., Pennesi, E., Willemse, M. E., Huitema, A. D. R., Jiang, Y., van Tinteren, H. D. R., van der Velden, V. H. J., Beverloo, B. H., den Boer, M. L., Rammeloo, L. A. J., Hudson, C., Heerema, N., Kowalski, K., Zhao, H., Kuttschreuter, L., Bautista Sirvent, F. J., Bukowinski, A., Rizzari, C., Pollard, J. & Murillo-Sanjuán, L. & 16 others, Kutny, M., Zarnegar-Lumley, S., Redell, M., Cooper, S., Bertrand, Y., Petit, A., Krystal, J., Metzler, M., Lancaster, D., Bourquin, J.-P., Motwani, J., van der Sluis, I. M., Locatelli, F., Roth, M. E., Hijiya, N. & Zwaan, C. M., 1 Mar 2024, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 42, 7, p. 821-831 11 p.

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Clinical Relevance of High Plasma Trough Levels of the Kinase Inhibitors Crizotinib, Alectinib, Osimertinib, Dabrafenib, and Trametinib in NSCLC Patients

Lin, L., Barkman, H. J., Smit, E. F., De Langen, A. J., Steeghs, N., Beijnen, J. H. & Huitema, A. D. R., 1 Feb 2024, In: Therapeutic drug monitoring. 46, 1, p. 73-79 7 p.

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Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of the antimalarial drug pyronaridine in human whole blood

Schouten, W. M., Roseboom, I. C., Lucas, L., Kabalu Tshiongo, J., Muhindo Mavoko, H., Kayentao, K., Rosing, H., Huitema, A. D. R., Beijnen, J. H. & Dorlo, T. P. C., 1 Aug 2024, In: Journal of Pharmaceutical and Biomedical Analysis. 245, 8 p., 116154.

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Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models

Damoiseaux, D., Beijnen, J. H., Huitema, A. D. R. & Dorlo, T. P. C., 16 Oct 2024, In: Drug Metabolism and Disposition. 52, 11, p. 1217-1223 7 p.

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ELISA assay for the quantification of ipilimumab in human serum, plasma, milk, and cerebrospinal fluid

Pluim, D., Buitelaar, P., de Jong, K. A. M., Rosing, H., Brandsma, D., Huitema, A. D. R. & Beijnen, J. H., 1 Aug 2024, In: Journal of Pharmaceutical and Biomedical Analysis. 245, 11 p., 116140.

Research output: Contribution to journal › Article › Academic › peer-review

Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort

Meertens, M., Giraud, E. L., van der Kleij, M. B. A., Westerdijk, K., Guchelaar, N. A. D., Bleckman, R. F., Rieborn, A., Imholz, A. L. T., Otten, H. M., Vulink, A., Los, M., Hamberg, P., van der Graaf, W. T. A., Gelderblom, H., Moes, D. J. A. R., Broekman, K. E., Touw, D. J., Koolen, S. L. W., Mathijssen, R. H. J. & Huitema, A. D. R. & 4 others, van Erp, N. P., Desar, I. M. E., Steeghs, N., Jul 2024, In: Clinical Pharmacokinetics. 63, 7, p. 1045-1054 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

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High-dose individualized antithymocyte globulin with therapeutic drug monitoring in high-risk cord blood transplant

Admiraal, R., Versluijs, A. B., Huitema, A. D. R., Ebskamp, L., Lacna, A., de Kanter, C. T. K., Bierings, M. B., Boelens, J. J., Lindemans, C. A. & Nierkens, S., Jun 2024, In: Cytotherapy. 26, 6, p. 599-605 7 p.

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Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data

Lau, C., Mohmaed Ali, M. I., Lin, L., van Balen, D. E. M., Jacobs, B. A. W., Nuijen, B., Smeenk, R. M., Steeghs, N. & Huitema, A. D. R., Jul 2024, In: Cancer Chemotherapy and Pharmacology. 94, 1, p. 25-34 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

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Is Higher Docetaxel Clearance in Prostate Cancer Patients Explained by Higher CYP3A? An In Vivo Phenotyping Study with Midazolam

van der Heijden, L. T., Ribbers, C. A., Vermunt, M. A. C., Pluim, D., Acda, M., Tibben, M., Rosing, H., Douma, J. A. J., Naipal, K., Bergman, A. M., Beijnen, J. H., Huitema, A. D. R. & Opdam, F. L., Feb 2024, In: Journal of Clinical Pharmacology. 64, 2, p. 155-163 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Leishmania blood parasite dynamics during and after treatment of visceral leishmaniasis in Eastern Africa: A pharmacokineticpharmacodynamic model

Verrest, L., Monnerat, S., Musa, A. M., Mbui, J., Khalil, E. A. G., Olobo, J., Wasunna, M., Chu, W. Y., Huitema, A. D. R., Schallig, H. D. F. H., Alves, F. & Dorlo, T. P. C., Apr 2024, In: PLoS neglected tropical diseases. 18, 4, e0012078.

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Maximizing treatment opportunities: assessing protocol waivers' impact on safety and outcome in the Drug Rediscovery Protocol

van Berge Henegouwen, J. M., Zeverijn, L. J., Geurts, B. S., Hoes, L. R., van der Wijngaart, H., van der Noort, V., Huitema, A. D. R., De Vos, F. Y. F., Grünberg, K., Bloemendal, H. J., Verheul, H. M. W., Voest, E. E. & Gelderblom, H., 3 Sept 2024, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 30, 17, p. 3937-3943 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Pharmacokinetics and Pharmacodynamics of Systemic Corticosteroids in Autoimmune and Inflammatory Diseases: A Review of Current Evidence

Möhlmann, J. E., Ezzafzafi, S., Lindemans, C. A., Jansen, M. H. A., Nierkens, S., Huitema, A. D. R. & van Luin, M., Sept 2024, In: Clinical Pharmacokinetics. 63, 9, p. 1251-1270 20 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

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Pharmacokinetics of PEGasparaginase in Infants with Acute Lymphoblastic Leukemia

Brigitha, L. J., Mondelaers, V., Liu, Y., Albertsen, B. K., Zalewska-Szewczyk, B., Rizzari, C., Kotecha, R. S., Pieters, R., Huitema, A. D. R. & van der Sluis, I. M., Apr 2024, In: Pharmaceutical Research. 41, 4, p. 711-720 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Platinum retention in plasma, urine, and normal colonic mucosa in cisplatin-treated testicular cancer survivors

Breekveldt, E. C. H., Ykema, B. L. M., Huitema, A. D. R., Gietema, J. A., Beijnen, J. H., Snaebjornsson, P., Schaapveld, M., van Leeuwen, F. E., Rosing, H., van Leerdam, M. E., 14 Nov 2024, In: PLoS ONE. 19, 11 November, p. e0312994 e0312994.

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Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates with Critical Congenital Heart Disease

Chu, W.-Y., Nijman, M., Stegeman, R., Breur, J. M. P. J., Jansen, N. J. G., Nijman, J., van Loon, K., Koomen, E., Allegaert, K., Benders, M. J. N. L., Dorlo, T. P. C., Huitema, A. D. R., Aug 2024, In: Clinical Pharmacokinetics. 63, 8, p. 1205-1220 16 p.

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Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Results of Study ITCC-059

Wu, J. H., Pennesi, E., Bautista, F., Garrett, M., Fukuhara, K., Brivio, E., Ammerlaan, A. C. J., Locatelli, F., van der Sluis, I. M., Rossig, C., Chen-Santel, C., Bielorai, B., Petit, A., Starý, J., Díaz-de-Heredia, C., Rives, S., O’Marcaigh, A., Rizzari, C., Engstler, G. & Nysom, K. & 10 others, Rubio-San-Simón, A., Bruno, B., Bertrand, Y., Brethon, B., Rialland, F., Plat, G., Dirksen, U., Sramkova, L., Zwaan, C. M. & Huitema, A. D. R., Jul 2024, In: Clinical Pharmacokinetics. 63, 7, p. 981-997 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

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Predictability of human exposure by human-CYP3A4-transgenic mouse models: A meta-analysis

Damoiseaux, D., Schinkel, A. H., Beijnen, J. H., Huitema, A. D. R. & Dorlo, T. P. C., Jan 2024, In: Clinical and Translational Science. 17, 1, 18 p., e13668.

Research output: Contribution to journal › Review article › peer-review

Open Access

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Propranolol monotherapy in angiosarcoma - A window-of-opportunity study (PropAngio)

Embaby, A., Heinhuis, K. M., IJzerman, N. S., Koenen, A. M., van der Kleij, S., Hofland, I., van Boven, H., Sanders, J., van der Graaf, W. T. A., Haas, R. L., Huitema, A. D. R., van Houdt, W. J. & Steeghs, N., May 2024, In: European Journal of Cancer. 202, 113974.

Research output: Contribution to journal › Article › Academic › peer-review

Quantification of biochemical PSA dynamics after radioligand therapy with [¹⁷⁷Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model

Siebinga, H., de Wit-van der Veen, B. J., de Vries-Huizing, D. M. V., Vogel, W. V., Hendrikx, J. J. M. A. & Huitema, A. D. R., 24 Apr 2024, In: EJNMMI physics. 11, 1, 24 p., 39.

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Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology - an analysis of the closed cohorts of a multicentre prospective study

van der Kleij, M. B. A., Guchelaar, N. A. D., Meertens, M., Westerdijk, K., Giraud, E. L., Bleckman, R. F., Groenland, S. L., van Eerden, R. A. G., Imholz, A. L. T., Vulink, A. J. E., Otten, H.-M., Fiebrich-Westra, H.-B., Lubberman, F. J. E., Desar, I. M. E., Moes, D.-J. A. R., Touw, D. J., Koolen, S. L. W., Gelderblom, H., Reyners, A. K. L. & van Erp, N. P. & 4 others, Mathijssen, R. H. J., Huitema, A. D. R., Steeghs, N., Sept 2024, In: British Journal of Cancer. 131, 5, p. 843-851 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

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Redispensing of expensive oral anticancer medicines: A practical application

Akgöl, K., van Merendonk, L. N., Barkman, H. J., van Balen, D. E., van den Hoek, H. L., Klous, M. G., Hendrikx, J. J., Huitema, A. D., Beijnen, J. H. & Nuijen, B., Apr 2024, In: Journal of Oncology Pharmacy Practice. 30, 3, p. 519-526 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Skin pharmacokinetics of miltefosine in the treatment of post-kala-azar dermal leishmaniasis in South Asia

Palić, S., Chu, W. Y., Sundar, S., Mondal, D., Das, P., Pandey, K., Raja, S., Rijal, S., Roseboom, I. C., Hamadeh, A., Malik, P. R. V., Beijnen, J. H., Huitema, A. D. R., Sjögren, E., Alves, F. & Dorlo, T. P. C., 1 Jul 2024, In: Journal of Antimicrobial Chemotherapy. 79, 7, p. 1547-1554 8 p.

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Sunitinib for the treatment of metastatic gastrointestinal stromal tumors: the effect of TDM-guided dose optimization on clinical outcomes

Jun 2024, In: ESMO open. 9, 6, 103477.

Research output: Contribution to journal › Article › Academic › peer-review

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The cycle effect quantified: reduced tumour uptake in subsequent cycles of [¹⁷⁷Lu]Lu-HA-DOTATATE during peptide receptor radionuclide therapy

Siebinga, H., Hendrikx, J. J. M. A., de Vries-Huizing, D. M. V., Huitema, A. D. R. & de Wit-van der Veen, B. J., Feb 2024, In: European Journal of Nuclear Medicine and Molecular Imaging. 51, 3, p. 820-827 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Therapeutic Drug Monitoring of Oral Oncology Drugs: Finding the Right Nails

Guchelaar, N. A. D., Institute, E., Steeghs, N., Huitema, A. D. R., Mathijssen, R. H. J. & Koolen, S. L. W., Sept 2024, In: Clinical Pharmacology and Therapeutics. 116, 3, p. 504-505 2 p.

Research output: Contribution to journal › Letter › Academic › peer-review

The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review

van der Heijden, L. T., Opdam, F. L., Beijnen, J. H. & Huitema, A. D. R., Jul 2024, In: European journal of drug metabolism and pharmacokinetics. 49, 4, p. 407-418 12 p.

Research output: Contribution to journal › Review article › peer-review

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Tocilizumab Dose Tapering Based on a Model-Based Algorithm is Feasible in Clinical Practice: A Short Communication

Hooijberg, F., Layegh, Z., Leeuw, M., Boekel, L., Van Den Berg, S. P. H., Ruwaard, J., Bastida, C., Huitema, A. D. R., Pel, S., Elkayam, O., De Vries, A., Nurmohamed, M., Rispens, T., Dorlo, T. P. C. & Wolbink, G., 1 Jun 2024, In: Therapeutic drug monitoring. 46, 3, p. 410-414 5 p.

Research output: Contribution to journal › Article › Academic › peer-review

Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

Lin, L., Houwink, A. P. I., van Dieren, J. M., Wolthuis, E. K., van Thienen, J. V., van der Heijden, M. S., Haanen, J. B. A. G., Beijnen, J. H. & Huitema, A. D. R., Jun 2024, In: Cancer Medicine. 13, 12, 7 p., e7302.

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Use of Sodium Thiosulfate as an Otoprotectant in Patients With Cancer Treated With Platinum Compounds: A Review of the Literature

Meijer, A. J. M., Diepstraten, F. A., Ansari, M., Bouffet, E., Bleyer, A., Fresneau, B., Geller, J. I., Huitema, A. D. R., Kogner, P., Maibach, R., O’Neill, A. F., Papadakis, V., Rajput, K. M., Veal, G. J., Sullivan, M., van den Heuvel-Eibrink, M. M. & Brock, P. R., 20 Jun 2024, In: Journal of Clinical Oncology. 42, 18, p. 2219-2232 14 p.

Research output: Contribution to journal › Review article › peer-review

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Vincristine exposure in Kenyan children with cancer: CHAPATI feasibility study

Uittenboogaard, A., van de Velde, M., van de Heijden, L., Mukuhi, L., de Vries, N., Langat, S., Olbara, G., Huitema, A. D. R., Vik, T., Kaspers, G. & Njuguna, F., Sept 2024, In: Pediatric Blood and Cancer. 71, 9, e31160.

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2023

A common germline variant in CYP11B1 is associated with adverse clinical outcome of treatment with abiraterone or enzalutamide

Buck, S. A. J., Meertens, M., van Ooijen, F. M. F., Oomen-de Hoop, E., de Jonge, E., Coenen, M. J. H., Bergman, A. M., Koolen, S. L. W., de Wit, R., Huitema, A. D. R., van Schaik, R. H. N. & Mathijssen, R. H. J., 31 Dec 2023, In: Biomedicine and Pharmacotherapy. 169, p. 1-7 7 p., 115890.

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A naïve pooled data approach for extrapolation of Phase 0 microdose trials to therapeutic dosing regimens

van der Heijden, L., van Nuland, M., Beijnen, J., Huitema, A. & Dorlo, T., Feb 2023, In: Clinical and Translational Science. 16, 2, p. 258-268 11 p.

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A physiologically based pharmacokinetic model for [⁶⁸Ga]Ga-(HA-)DOTATATE to predict whole-body distribution and tumor sink effects in GEP-NET patients

Siebinga, H., de Wit-van der Veen, B. J., Beijnen, J. H., Dorlo, T. P. C., Huitema, A. D. R. & Hendrikx, J. J. M. A., 3 Feb 2023, In: EJNMMI Research. 13, 1, 16 p., 8.

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A sensitive liquid chromatographic-mass spectrometry method for the quantification of vincristine in whole blood collected with volumetric absorptive microsampling

van der Heijden, L. T., Uittenboogaard, A., Nijstad, A. L., Gebretensae, A., Kaspers, G. J. L., Beijnen, J. H., Huitema, A. D. R. & Rosing, H., 20 Feb 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 225, 115232.

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Scopus)

A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children

Nijstad, A. L., de Vos-Kerkhof, E., Enters-Weijnen, C. F., van de Wetering, M. D., Tissing, W. J. E., Hanff, L. M., Lange, R., Tibben, M. M., Rosing, H., Lalmohamed, A., Zwaan, C. M. & Huitema, A. D. R., Jun 2023, In: Journal of Oncology Pharmacy Practice. 29, 4, p. 899-904 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Azacitidine (Vidaza^®) in Pediatric Patients with Relapsed Advanced MDS and JMML: Results of a Phase I/II Study by the ITCC Consortium and the EWOG-MDS Group (Study ITCC-015)

Rubio-San-Simón, A., van Eijkelenburg, N. K. A., Hoogendijk, R., Hasle, H., Niemeyer, C. M., Dworzak, M. N., Zecca, M., Lopez-Yurda, M., Janssen, J. M., Huitema, A. D. R., van den Heuvel-Eibrink, M. M., Laille, E. J., van Tinteren, H. & Zwaan, C. M., Nov 2023, In: Pediatric Drugs. 25, 6, p. 719-728 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Clinical development of WEE1 inhibitors in gynecological cancers: A systematic review

Schutte, T., Embaby, A., Steeghs, N., van der Mierden, S., van Driel, W., Rijlaarsdam, M., Huitema, A. & Opdam, F., Apr 2023, In: Cancer Treatment Reviews. 115, 15 p., 102531.

Research output: Contribution to journal › Review article › peer-review

Open Access

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Combination therapy with crizotinib and vinblastine for relapsed or refractory pediatric ALK-positive anaplastic large cell lymphoma

Knörr, F., Schellekens, K. P. J., Schoot, R. A., Landman-Parker, J., Teltschik, H. M., Förster, J., Riquelme, A., Huitema, A. D. R., van Eijkelenburg, N. K. A., Beishuizen, A., Zwaan, C. M., Woessmann, W. & van der Lugt, J., May 2023, In: Haematologica. 108, 5, p. 1442-1446 5 p.

Research output: Contribution to journal › Letter › Academic › peer-review

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3 Citations (Scopus)

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Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate

Bruin, M. A. C., Mohmaed Ali, M. I., van Nuland, M., Jacobs, B. A. W., Lucas, L., Dezentje, V. O., de Feijter, J. M., Rosing, H., Bergman, A. M., Beijnen, J. H. & Huitema, A. D. R., Dec 2023, In: Pharmaceutical Research. 40, 12, p. 3001-3010 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients

Aug 2023, In: Clinical Pharmacokinetics. 62, 8, p. 1129-1139 11 p.

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Design and statistics of pharmacokinetic drug-drug, herb-drug, and food-drug interaction studies in oncology patients

Lanser, D. A. C., Van der Kleij, M. B. A., Veerman, G. D. M., Steeghs, N., Huitema, A. D. R., Mathijssen, R. H. J. & Oomen-de Hoop, E., Jul 2023, In: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. 163, 6 p., 114823.

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Development of a Therapeutic Drug Monitoring Strategy for the Optimization of Vincristine Treatment in Pediatric Oncology Populations in Africa

Van Der Heijden, L. T., Nijstad, A. L., Uittenboogaard, A., Beijnen, J. H., Dorlo, T. P. C., Kaspers, G. J. L. & Huitema, A. D. R., 1 Jun 2023, In: Therapeutic drug monitoring. 45, 3, p. 354-363 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Alwin Huitema

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