Personal profile
Biography
Dr. van Mil is a biomedical scientist and group leader in the laboratory of Experimental Cardiology within the Regenerative Medicine Center Utrecht. He obtained his PhD in 2012 in the University Medical Center Utrecht where he studied the role of microRNAs in cardiac regeneration and subsequently moved to the US for a postdoctoral fellowship in Sanford-Burnham, La Jolla, where he first came to work with pluripotent stem cells and in vitro 3D cardiac tissue models. After his return to the Netherlands, he continued his research in the UMC Utrecht using pluripotent stem cells, applying them for cardiac disease modelling. In 2016 he moved to the Regenerative Medicine Center Utrecht, where he established an induced pluripotent stem cell (iPSC) facility for the generation of iPSCs and iPSC-derived cardiac cells which are key to his research. His research team aims to identify new therapeutic targets and develop regenerative treatments for heart failure, by using advanced human in vitro cardiac disease models and innovative cardiac tissue engineering approaches, using iPSC technology, biomaterials and 3D printing.
Collaborations and top research areas from the last five years
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Author Correction: Engineering anti-BCMA CAR T cells for enhancing myeloma killing efficacy via apoptosis regulation
Kimman, T., Cuenca, M., Tieland, R. G., Rockx-Brouwer, D., Janssen, J., Motais, B., Slomp, A., Pleijte, C., Heijhuurs, S., Meringa, A. D., Boschloo, W., Bosma, D. M. T., Kroos, S., Lo Presti, V., Sluijter, J. P. G., Nierkens, S., Bovenschen, N., Kuball, J., van Mil, A. & Minnema, M. C. & 2 others, , 13 Apr 2026, In: Nature Communications. 17, 1, 3442.Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review
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From Fiber Architecture to Functional Attachment: A Clinically Relevant, Mechanically Tunable Cardiac Patch
Braig, J., Kent, R., Goienetxe, A. G., Laita, N., Wu, M., Martínez, M. Á., Serra, M., Janssens, K., Urtaza, U., Larequi, E., Anaut-Lusar, I., Gillijns, H., Algoet, M., van Kerkhof, B., van der Knaap, M., Cedillo-Servin, G., Castilho, M., van Mil, A., Sluijter, J. P. G. & Malda, J. & 12 others, , 20 Mar 2026, In: Advanced materials. 38, 17, e15863.Research output: Contribution to journal › Article › Academic › peer-review
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LAH5-mediated delivery of prime editor ribonucleoprotein complexes for genome editing
Yao, B., Öktem, M., Yang, G., Wang, Q., Daniels, M. A., Dokter, I., Lefferts, J. W., Gonçalves, M. A. F. V., Doevendans, P. A., van Mil, A., Sluijter, J. P. G., Schiffelers, R., Mastrobattista, E. & Lei, Z., 10 Mar 2026, In: International Journal of Pharmaceutics. 692, 10 p., 126622.Research output: Contribution to journal › Article › Academic › peer-review
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Photoporation enables non-viral delivery of prime editing RNP complexes into human iPSC-derived cardiomyocytes for cardiac genome correction
Yao, B., Yang, G., Wang, Q., Daniels, M. A., Dokter, I., Shang, P., van Mil, A., Doevendans, P. A., Gonçalves, M. A. F. V., Stillitano, F., Sluijter, J. P. G., Schiffelers, R. & Lei, Z., May 2026, In: Biomedicine and Pharmacotherapy. 198, 119238.Research output: Contribution to journal › Article › Academic › peer-review
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Billion-Scale Expansion of Functional hiPSC-Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation
Vicente, P., Inocêncio, L. R., Ullate-Agote, A., Louro, A. F., Jacinto, J., Gamelas, B., Iglesias-García, O., Martin-Uriz, P. S., Aguirre-Ruiz, P., Ríos-Muñoz, G. R., Fernández-Santos, M. E., van Mil, A., Sluijter, J. P. G., Prósper, F., Vega, M. M. M., Alves, P. M. & Serra, M., Mar 2025, In: Advanced Science. 12, 11, 17 p., 2410510.Research output: Contribution to journal › Article › Academic › peer-review
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