University Medical Center (UMC) Utrecht

2025

Catching Houdini - targeting TP53-deficient ALL

Cox, W. P. J., 23 Jan 2025, Utrecht: Utrecht University. 189 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

2024

ABL family genes in pediatric acute lymphoblastic leukemia: Molecular determinants of tyrosine kinase inhibitor response

Outersterp, I. V., 2 Apr 2024, Utrecht University. 170 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Antibody responses and B cell immunity after pertussis booster vaccination: immunity in young and old in times of endemic pertussis

Versteegen, P., 28 May 2024, Utrecht: Utrecht University. 244 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Biomarker-driven treatment strategies in solid tumors: Insights from clinical and translational research

Embaby, A., 21 May 2024, Utrecht: Utrecht University. 236 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Biomarkers and phenotype concepts in sarcoidosis care

Schimmelpennink, M. C., 12 Mar 2024, Utrecht: Utrecht University. 194 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

14 Downloads (Pure)

Biomarkers for clinical benefit to immune checkpoint blockade treatment in NSCLC

Hummelink, K., 12 Nov 2024, Utrecht University. 304 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Broadening mould-active strategies in paediatric haemato-oncology patients

Bury, D., 11 Jun 2024, Utrecht University. 195 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Changes in the use of continuous deep sedation in the Netherlands

Heijltjes, M., 3 Apr 2024, Utrecht University. 187 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

1 Downloads (Pure)

Children with a chronic illness or cancer, their siblings and parents: psychosocial group intervention & long-term consequences

Joosten, M. M. H., 30 May 2024, Utrecht University. 183 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

1 Downloads (Pure)

Clinical implementation of new diagnostic modalities in the era of precision oncology: Path to Precision

Schipper, L. J., 25 Apr 2024, Utrecht University. 190 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

19 Downloads (Pure)

Combine and conquer as a strategy to treat RAS-driven cancers

Jansen, R. A., 23 Apr 2024, Utrecht University. 143 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

3 Downloads (Pure)

Common Idiopathic Mononeuropathies of the Upper Extremity

Kortlever, J. T. P., 23 May 2024, Utrecht: Utrecht University. 290 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

1 Downloads (Pure)

Complexity in Simplicity: Unraveling the Heterogeneous Nature of Malignant Rhabdoid Tumors

Paassen, I. E. K., 20 Sept 2024, Utrecht University. 215 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Decoding Heavy Hearts: Molecular Insights into Hypertrophic Cardiomyopathy

de Leeuw, A. E., 28 Mar 2024, Utrecht: Utrecht University. 204 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

31 Downloads (Pure)

Deviating in white: Rebel nurse leadership in the nursing practice

de Kok, E., 16 Jan 2024, Utrecht University. 214 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

124 Downloads (Pure)

Dual perspectives: Cellular differentiation in health and disease

DeMartino, J., 14 Nov 2024, Utrecht University. 278 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Elucidating virus-host interactions and viral immune evasion strategies using genetic editing and screening technologies

Zheng, S., 4 Sept 2024, Utrecht: Utrecht University. 242 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

FDG PET/CT in Prosthetic Heart Valve Endocarditis

Scholtens, A., 18 Jun 2024, Utrecht: Utrecht University. 248 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Finding Balance in the Chaos: Causes and Consequences of Karyotype Deviations

Hintzen, D. C., 20 Jun 2024, Utrecht University. 174 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

1 Downloads (Pure)

Finding the hidden patterns: single-cell omics to reduce late effects

de Kanter, J. K., 9 Apr 2024, Utrecht: Utrecht University. 242 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

51 Downloads (Pure)

Focused Ultrasound-mediated Blood-Brain Barrier Opening for Diffuse Midline Glioma Radiosensitisation

't Hart, E., 19 Mar 2024, Utrecht: Utrecht University. 183 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

8 Downloads (Pure)

Formation and function of binucleated human hepatocytes

Darmasaputra, G. S., 11 Jan 2024, Utrecht University. 135 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

From Single Cells to 3D Cultures: Fundamental research on Neuroblastoma and Medulloblastoma

Hanemaaijer, E. S., 8 Oct 2024, Utrecht University. 167 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Genetic dissection of the 11q13 amplicon in squamous cell carcinoma

Mahieu, C. I., 25 Apr 2024, Utrecht University. 188 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

8 Downloads (Pure)

Genomics-guided Oncology: Advancing Efficacy and Access

Zeverijn, L. J., 28 Nov 2024, Utrecht University. 255 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

3 Downloads (Pure)

GEOGRAPHY OF A RARE DISEASE: A SHIFTING LANDSCAPE TOWARDS DIFFUSE MIDLINE GLIOMA (DMG)

Baugh, J. N., 1 Oct 2024, Utrecht University. 210 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Germ cell tumor treatment resistance and liquid biopsy-based microRNA biomarkers

Timmerman, D. M., 23 Jan 2024, Utrecht: Utrecht University. 259 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

14 Downloads (Pure)

Grasping the Complexity of Anti-Tumor Immunity: Looking at T cells and beyond

Veninga, V., 7 May 2024, Utrecht: Utrecht University. 248 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

13 Downloads (Pure)

Imaging to predict checkpoint inhibitor outcomes in advanced melanoma

ter Maat, R., 27 Nov 2024, Utrecht University. 147 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

3 Downloads (Pure)

Improving quality of survival after childhood cancer by developing, implementing and evaluating care

van Kalsbeek-Grootendorst, R. J., 4 Jun 2024, Utrecht University. 298 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Improving the evidence base for diagnosis and management of cutaneous leishmaniasis

Henten, S. C. V., 6 Mar 2024, Utrecht University. 231 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

9 Downloads (Pure)

Inter- and Intraspecies extrapolation for the exploration of the pharmacokinetics in untapped populations

Damoiseaux, D., 28 Mar 2024, Utrecht: Utrecht University. 236 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

7 Downloads (Pure)

LNPs for targeted siRNA delivery to leukemic tissue

Swart, L. E., 7 Oct 2024, Utrecht: Utrecht University. 244 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Merging Macro and Micro: Transcriptional landscapes and in-depth studies for understanding heart disease

Timmer, L. T., 23 Sept 2024, Utrecht University. 231 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

1 Downloads (Pure)

New Insights in the Detection and Staging of Prostate Cancer

Heetman, J. G., 19 Sept 2024, Utrecht University. 216 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Notch signalling dynamics during mouse development and homeostasis

el Azhar, Y., 3 Dec 2024, Utrecht University. 140 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

1 Downloads (Pure)

Nurses’ support of hospitalized patients’ self-management

Otter, C. E. M., 1 Feb 2024, Utrecht University. 257 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

33 Downloads (Pure)

One Chaperone to Rule Them All: Deciphering How Chromatin is Assembled During DNA Replication

Rouillon, C., 4 Jul 2024, Utrecht University. 178 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

4 Downloads (Pure)

On the road to optimizing long-term survival: Subsequent neoplasms in childhood cancer survivors across five decades

Westerveld, A. S. R., 10 Dec 2024, Utrecht University. 170 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Optimization of central venous access care in pediatric oncology patients

van den Bosch, C. H., 3 Oct 2024, Utrecht: Utrecht University. 353 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Outcomes and their determinants in patients with sudden cardiac arrest: Population health approaches to improve clinical outcomes

Ho, A. F. W., 18 Jan 2024, Utrecht University. 188 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

57 Downloads (Pure)

Outsmarting therapy resistant leukemia: Using CRISPR screens for rational design of novel treatment strategies

Vervoort, B., 2 Jul 2024, Utrecht University. 210 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

2 Downloads (Pure)

Plugging the brain drain: exploring brain tumor dynamics and effective treatments

Uceda-Castro, R., 6 May 2024, Utrecht: Utrecht University. 242 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

3 Downloads (Pure)

Protein tyrosine phosphatases in zebrafish development and regeneration

Allers, M., 30 Jan 2024, Utrecht: Utrecht University. 177 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

10 Downloads (Pure)

Pulling the Strings: Exploiting Metabolic Dependencies in Pediatric Cancer

Tee, T. M., 24 Oct 2024, Utrecht: Utrecht University. 207 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

Push it over the limit: Elevating DNA double-strand break toxicity

Koob, L., 15 Feb 2024, Utrecht University. 234 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Open Access

File

25 Downloads (Pure)

Space odyssey: characterizing transcriptional regulation at a distance

Huang, Y., 11 Jan 2024, Utrecht: Utrecht University. 177 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Structural variation in pediatric cancer: characterizing tumor genomes to improve patient care

van Belzen, I. A. E. M., 17 Oct 2024, Utrecht University. 268 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

Tailoring treatment in early-stage breast cancer: The identification of prognostic and predictive biomarkers in HER2-negative and triple-negative breast cancer

de Boo, L. W., 23 Sept 2024, Utrecht University. 229 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

The growing value of real-world evidence: From exploring the many potential uses of real-world data to improving its efficient use within the field of oncology

Lin, L., 28 May 2024, Utrecht: Utrecht University. 272 p.

Research output: Thesis › Doctoral thesis 2 (Research NOT UU / Graduation UU)

University Medical Center (UMC) Utrecht

Research output

Search results