Research UMC Utrecht

Research output

Research output per year 1979 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2024

• 45727 Article
• 3034 Review article
• 2717 Doctoral thesis 1 (Research UU / Graduation UU)
• 1885 Comment/Letter to the editor
• 6837 More
  • 1480 Meeting Abstract
  • 1411 Chapter
  • 696 Abstract
  • 659 Letter
  • 532 Editorial
  • 470 Poster
  • 316 Doctoral thesis 2 (Research NOT UU / Graduation UU)
  • 291 Conference contribution
  • 182 Paper
  • 148 Literature review
  • 121 Short survey
  • 120 Other contribution
  • 103 Book
  • 54 Book editing
  • 53 Report
  • 45 Preprint
  • 44 Inaugural speech
  • 24 Doctoral thesis 3 (Research UU / Graduation NOT UU)
  • 21 Patent
  • 17 Web publication/site
  • 12 Other
  • 9 Foreword/postscript
  • 8 Book/Film/Article review
  • 5 Special issue
  • 5 Software
  • 4 Entry for encyclopedia/dictionary
  • 4 Digital or Visual Products
  • 2 Working paper
  • 1 Data set/Database

Research output per year

Research output per year

Search results

• 2024

  A fully synthetic three-dimensional human cerebrovascular model based on histological characteristics to investigate the hemodynamic fingerprint of the layer BOLD fMRI signal formation

  Báez-Yáñez, M. G., Schellekens, W., Bhogal, A. A., Roefs, E. C. A., van Osch, M. J. P., Siero, J. CW. & Petridou, N., 26 May 2024, BioRxiv, p. 1-38.

  Research output: Working paper › Preprint › Academic

  File

• Biallelic variants in POPDC2 cause a novel autosomal recessive syndrome presenting with cardiac conduction defects and variable hypertrophic cardiomyopathy

  Nicastro, M., Vermeer, A. M. C., Postema, P. G., Tadros, R., Bowling, F. Z., Aegisdottir, H. M., Tragante, V., Mach, L., Postma, A. V., Lodder, E. M., van Duijvenboden, K., Zwart, R., Beekman, L., Wu, L., van der Zwaag, P. A., Alders, M., Allouba, M., Aguib, Y., Santomel, J. L., de Una, D., & 50 othersMonserrat, L., Miranda, A. M. A., Kanemaru, K., Cranley, J., van Zeggeren, I. E., Aronica, E. M. A., Ripolone, M., Zanotti, S., Sveinbjornsson, G., Ivarsdottir, E. V., Hólm, H., Guðbjartsson, D. F., Skúladóttir, Á. T., Stefánsson, K., Nadauld, L., Knowlton, K. U., Ostrowski, S. R., Sørensen, E., Vesterager Pedersen, O. B., Ghouse, J., Rand, S., Bundgaard, H., Ullum, H., Erikstrup, C., Aagaard, B., Bruun, M. T., Christiansen, M., Jensen, H. K., Carere, D. A., Cummings, C. T., Fishler, K., Tøring, P. M., Brusgaard, K., Juul, T. M., Saaby, L., Winkel, B. G., Mogensen, J., Fortunato, F., Comi, G. P., Ronchi, D., van Tintelen, J. P., Noseda, M., Airola, M. V., Christiaans, I., Wilde, A. A. M., Wilders, R., Clur, S-A., Verkerk, A. O., Bezzina, C. R. & Lahrouchi, N., 5 Jul 2024, medRxiv, 49 p. (medRxiv).

  Research output: Working paper › Preprint › Academic

• Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts

  Wani, A., Katrinli, S., Zhao, X., Daskalakis, N., Zannas, A., Aiello, A., Baker, D., Boks, M., Brick, L., Chen, C-Y., Dalvie, S., Fortier, C., Geuze, E., Hayes, J., Kessler, R., King, A., Koen, N., Liberzon, I., Lori, A., Luykx, J., & 22 othersMaihofer, A., Milberg, W., Miller, M., Mufford, M., Nugent, N., Rauch, S., Ressler, K., Risbrough, V., Rutten, B., Stein, D., Stein, M., Ursano, R., Verfaellie, M., Ware, E., Wildman, D., Wolf, E., Nievergelt, C., Logue, M., Smith, A., Uddin, M., Vermetten, E. & Vinkers, C., 15 Feb 2024, Research Square, 31 p.

  Research output: Working paper › Preprint › Academic

  File

• Don't put words in my mouth: Speech perception can generate False Positive activation of a speech BCI

  Schippers, A., Vansteensel, M. J., Freudenburg, Z. V. & Ramsey, N. F., 22 Jan 2024, medRxiv, (medRxiv).

  Research output: Working paper › Preprint › Academic

  Open Access

  • Brain-Computer Interfaces 100%
  • Speech Perception 90%
  • Mouth 63%
  • Electrocorticography 14%
  • Sensorimotor Cortex 12%

• Enhancing Cognitive Performance Prediction through White Matter Hyperintensity Connectivity Assessment: A Multicenter Lesion Network Mapping Analysis of 3,485 Memory Clinic Patients

  Petersen, M., Coenen, M., DeCarli, C., De Luca, A., van der Lelij, E., Barkhof, F., Benke, T., Chen, C. P. L. H., Dal-Bianco, P., Dewenter, A., Duering, M., Enzinger, C., Ewers, M., Exalto, L. G., Fletcher, E. F., Franzmeier, N., Hilal, S., Hofer, E., Koek, H. L., Maier, A. B., & 21 othersMaillard, P. M., McCreary, C. R., Papma, J. M., Pijnenburg, Y. A. L., Schmidt, R., Smith, E. E., Steketee, R. M. E., van den Berg, E., van der Flier, W. M., Venkatraghavan, V., Venketasubramanian, N., Vernooij, M. W., Wolters, F. J., Xu, X., Horn, A., Patil, K. R., Eickhoff, S. B., Thomalla, G., Biesbroek, J. M., Biessels, G. J. & Cheng, B., 11 Apr 2024, medRxiv, 15 p.

  Research output: Working paper › Preprint › Academic

  File

  • White Matter 100%
  • Memory 80%
  • Cognitive Dysfunction 54%
  • Brain 53%
  • Gray Matter 44%

• Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts

  Katrinli, S., Wani, A. H., Maihofer, A. X., Ratanatharathorn, A., Daskalakis, N. P., Montalvo-Ortiz, J., Núñez-Ríos, D. L., Zannas, A. S., Zhao, X., Aiello, A. E., Ashley-Koch, A. E., Avetyan, D., Baker, D. G., Beckham, J. C., Boks, M. P., Brick, L. A., Bromet, E., Champagne, F. A., Chen, C-Y., Dalvie, S., & 30 othersDennis, M. F., Fatumo, S., Fortier, C., Galea, S., Garrett, M. E., Geuze, E., Grant, G., Michael A Hauser, Hayes, J. P., Hemmings, S. M., Huber, B. R., Jajoo, A., Jansen, S., Kessler, R. C., Kimbrel, N. A., King, A. P., Kleinman, J. E., Koen, N., Koenen, K. C., Kuan, P-F., Liberzon, I., Linnstaedt, S. D., Lori, A., Luft, B. J., Luykx, J. J., Marx, C. E., McLean, S. A., Rutten, B. P. F., Vermetten, E. & Vinkers, C. H., 15 Jul 2024, medRxiv, 46 p. (medRxiv).

  Research output: Working paper › Preprint › Academic

  File

• Fibroblasts as an in vitro model of circadian genetic and genomic studies: A temporal analysis

  Francia, M., Bot, M., Boltz, T., De la Hoz, J. F., Boks, M., Kahn, R. & Ophoff, R., 5 Mar 2024, BioRxiv, 28 p.

  Research output: Working paper › Preprint › Academic

  File

• Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci

  13 Mar 2024, medRxiv, p. 1-55, 55 p.

  Research output: Working paper › Preprint › Academic

  File

  • Obsessive-Compulsive Disorder 100%
  • Genome-Wide Association Study 94%
  • Single Nucleotide Polymorphism 37%
  • Single-Cell Analysis 20%
  • Tourette Syndrome 19%

• GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases

  Lesmann, H., Hustinx, A., Moosa, S., Klinkhammer, H., Marchi, E., Caro, P., Abdelrazek, I. M., Pantel, J. T., Hagen, M. T., Thong, M-K., Binti Mazlan, R. A., Tae, S. K., Kamphans, T., Meiswinkel, W., Li, J-M., Javanmardi, B., Knaus, A., Uwineza, A., Knopp, C., Tkemaladze, T., & 30 othersElbracht, M., Mattern, L., Jamra, R. A., Velmans, C., Strehlow, V., Jacob, M., Peron, A., Dias, C., Nunes, B. C., Vilella, T., Pinheiro, I. F., Kim, C. A., Melaragno, M. I., Weiland, H., Kaptain, S., Chwiałkowska, K., Kwasniewski, M., Saad, R., Wiethoff, S., Goel, H., Tang, C., Hau, A., Barakat, T. S., Panek, P., Nabil, A., Suh, J., Braun, F., Gomy, I., Averdunk, L. & Oegema, R., 10 Jun 2024, Research Square, 51 p. (Research square).

  Research output: Working paper › Preprint › Academic

  File

• Heterogeneity of morphometric similarity networks in health and schizophrenia

  Janssen, J., Gallego, A. G., Díaz-Caneja, C. M., Lois, N. G., Janssen, N., González-Peñas, J., Gordaliza, P. M., Buimer, E. E. L., van Haren, N. E. M., Arango, C., Kahn, R. S., Hulshoff Pol, H. E. & Schnack, H. G., 18 Jun 2024, BioRxiv, 46 p. (bioRxiv).

  Research output: Working paper › Preprint › Academic

  File

  • Schizophrenia 100%
  • Health 59%
  • Psychotic Disorders 22%
  • Neuroimaging 22%
  • Reference Values 19%

• Identifying genetic differences between bipolar disorder and major depression through multiple GWAS

  30 Jan 2024, medRxiv, 46 p.

  Research output: Working paper › Preprint › Academic

  File

• IFNγ induces epithelial reprogramming driving CXCL11-mediated T cell migration

  Cutilli, A., Jansen, S. A., Paolucci, F., Mokry, M., Mocholi, E., Lindemans, C. A. & Coffer, P. J., 7 Feb 2024, BioRxiv, (bioRxiv).

  Research output: Working paper › Preprint › Academic

  • Organoids 100%
  • Interferon-gamma 68%
  • Cell Movement 62%
  • T-Lymphocytes 47%
  • Chemokine CXCL11 33%

• On the influence of the vascular architecture on Gradient Echo and Spin Echo BOLD fMRI signals across cortical depth: a simulation approach based on realistic 3D vascular networks

  Báez-Yáñez, M. G., Siero, J. C. W., Curcic, V., van Osch, M. J. P. & Petridou, N., 30 May 2024, BioRxiv, 33 p. (bioRxiv).

  Research output: Working paper › Preprint › Academic

  File

  • Magnetic Resonance Imaging 100%
  • Blood Vessels 88%
  • Hemodynamics 37%
  • Oxygen 35%

• Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordings

  Lei, C. L., Clark, A. P., Clerx, M., Wei, S., Bloothooft, M., de Boer, T. P., Christini, D. J., Krogh-Madsen, T. & Mirams, G. R., 24 Jul 2024, BioRxiv, 19 p. (bioRxiv).

  Research output: Working paper › Preprint › Academic

  File

• Structural brain abnormalities and aggressive behaviour in schizophrenia: Mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium

  5 Feb 2024, medRxiv, 20 p.

  Research output: Working paper › Preprint › Academic

  File

• Unveiling the crucial neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies.

  Küry, S., Stanton, J. E., van Woerden, G., Hsieh, T-C., Rosenfelt, C., Scott-Boyer, M. P., Most, V., Wang, T., Papendorf, J. J., de Konink, C., Deb, W., Vignard, V., Studencka-Turski, M., Besnard, T., Hajdukowicz, A. M., Thiel, F., Möller, S., Florenceau, L., Cuinat, S., Marsac, S., & 111 othersWentzensen, I., Tuttle, A., Forster, C., Striesow, J., Golnik, R., Ortiz, D., Jenkins, L., Rosenfeld, J. A., Ziegler, A., Houdayer, C., Bonneau, D., Torti, E., Begtrup, A., Monaghan, K. G., Mullegama, S. V., Volker-Touw, C. M. L. N., van Gassen, K. L. I., Oegema, R., de Pagter, M., Steindl, K., Rauch, A., Ivanovski, I., McDonald, K., Boothe, E., Dauber, A., Baker, J., Fabie, N. A. V., Bernier, R. A., Turner, T. N., Srivastava, S., Dies, K. A., Swanson, L., Costin, C., Jobling, R. K., Pappas, J., Rabin, R., Niyazov, D., Tsai, A. C-H., Kovak, K., Beck, D. B., Malicdan, M., Adams, D. R., Wolfe, L., Ganetzky, R. D., Muraresku, C., Babikyan, D., Sedláček, Z., Hančárová, M., Timberlake, A. T., Al Saif, H., Nestler, B., King, K., Hajianpour, M. J., Costain, G., Prendergast, DA., Li, C., Geneviève, D., Vitobello, A., Sorlin, A., Philippe, C., Harel, T., Toker, O., Sabir, A., Lim, D., Hamilton, M., Bryson, L., Cleary, E., Weber, S., Hoffman, T. L., Cueto-González, A. M., Tizzano, E. F., Gómez-Andrés, D., Codina-Solà, M., Ververi, A., Pavlidou, E., Lambropoulos, A., Garganis, K., Rio, M., Levy, J., Jurgensmeyer, S., McRae, A. M., Lessard, M. K., D'Agostino, M. D., De Bie, I., Wegler, M., Jamra, R. A., Kamphausen, S. B., Bothe, V., Busch, L. M., Völker, U., Hammer, E., Wende, K., Cogné, B., Isidor, B., Meiler, J., Bosc-Rosati, A., Marcoux, J., Bousquet, M-P., Poschmann, J., Laumonnier, F., Hildebrand, P. W., Eichler, E. E., McWalter, K., Krawitz, P. M., Droit, A., Elgersma, Y., Grabrucker, A. M., Bolduc, F. V., Bézieau, S., Ebstein, F. & Krüger, E., 26 Jan 2024, medRxiv.

  Research output: Working paper › Preprint › Academic

  • Neurodevelopmental Disorders 100%
  • Adenosine Triphosphatases 85%
  • ATPases Associated with Diverse Cellular Activities 63%
  • Reversal Learning 61%
  • ATP dependent 26S protease 59%
• 2023

  A click-based electrocorticographic brain-computer interface enables long-term high-performance switch-scan spelling

  Crone, N., Candrea, D., Shah, S., Luo, S., Angrick, M., Rabbani, Q., Coogan, C., Milsap, G., Nathan, K., Wester, B., Anderson, W., Rosenblatt, K., Clawson, L., Maragakis, N., Vansteensel, M., Tenore, F., Ramsey, N., Fifer, M. & Uchil, A., 25 Sept 2023, Research Square, p. 1-26, 26 p.

  Research output: Working paper › Preprint › Academic

  File

• A multidimensional analysis reveals distinct immune phenotypes and tertiary lymphoid structure-like aggregates in the bone marrow of pediatric acute myeloid leukemia

  Koedijk, J. B., van der Werf, I., Penter, L., Vermeulen, M. A., Barneh, F., Perzolli, A., Meesters-Ensing, J. I., Fiocco, M., de Groot-Kruseman, H. A., Moeniralam, R., Christensen, K. B., Porter, B., Pfaff, K., Garcia, J. S., Rodig, S. J., Wu, C. J., Hasle, H., Nierkens, S., Belderbos, M. E., Zwaan, C. M., & 1 othersHeidenreich, O., 30 Oct 2023, medRxiv.

  Research output: Working paper › Preprint › Academic

  Open Access

  • Tertiary Lymphoid Structures 100%
  • Acute Myeloid Leukemia 56%
  • Bone Marrow 43%
  • Pediatrics 38%
  • Phenotype 35%

• Beyond gene-disease validity: capturing structured data on inheritance, allelic-requirement, disease-relevant variant classes, and disease mechanism for inherited cardiac conditions

  Josephs, K. S., Roberts, A. M., Theotokis, P., Walsh, R., Ostrowski, P. J., Edwards, M., Fleming, A., Thaxton, C., Roberts, J. D., Care, M., Zareba, W., Adler, A., Sturm, A. C., Tadros, R., Novelli, V., Owens, E., Bronicki, L., Jarinova, O., Callewaert, B., Peters, S., & 15 othersLumbers, T., Jordan, E., Asatryan, B., Krishnan, N., Hershberger, R. E., Chahal, C. A. A., Landstrom, A. P., James, C., McNally, E. M., Judge, D. P., van Tintelen, P., Wilde, A., Gollob, M., Ingles, J. & Ware, J. S., 3 Apr 2023, medRxiv.

  Research output: Working paper › Preprint › Academic

  File

  • Genes 100%
  • Inheritance Patterns 53%
  • Datasets 32%
  • Proteins 15%
  6 Downloads (Pure)

• Cell type deconvolution of bulk blood RNA-Seq to reveal biological insights of neuropsychiatric disorders

  Boltz, T., Schwarz, T., Bot, M., Hou, K., Caggiano, C., Lapinska, S., Duan, C., Boks, M. P., Kahn, R. S., Zaitlen, N., Pasaniuc, B. & Ophoff, R., 25 May 2023, BioRxiv.

  Research output: Working paper › Preprint › Academic

  Open Access

  File

  • RNA-Seq 100%
  • Lithium 20%
  • Genome-Wide Association Study 19%
  • Bipolar Disorder 18%
  • Schizophrenia 15%
  21 Downloads (Pure)

• Chemotherapy-induced intestinal injury promotes Galectin-9-driven modulation of T cell function

  Jansen, S. A., Cutilli, A., de Koning, C., van Hoesel, M., Sierra, L. S., Nierkens, S., Mokry, M., Nieuwenhuis, E. E. S., Hanash, A. M., Mocholi, E., Coffer, P. J. & Lindemans, C. A., 30 Apr 2023, BioRxiv, (bioRxiv).

  Research output: Working paper › Preprint › Academic

  • Galectins 100%
  • Organoids 71%
  • Cell Transplantation 58%
  • Allogeneic Cells 58%
  • Graft vs Host Disease 57%

• Colchicine promotes atherosclerotic plaque stability independently of inflammation

  Li, W., Lin, A., Hutton, M., Dhaliwal, H., Nadel, J., Rodor, J., Tumanov, S., Örd, T., Hadden, M., Mokry, M., Mol, B. M., Pasterkamp, G., Padula, M. P., Geczy, C. L., Ramaswamy, Y., Sluimer, J. C., Kaikkonen, M. U., Stocker, R., Baker, A. H., Fisher, E. A., & 2 othersPatel, S. & Misra, A., 3 Oct 2023, BioRxiv, 22 p. (bioRxiv).

  Research output: Working paper › Preprint › Academic

  • Colchicine 100%
  • Atherosclerotic Plaques 90%
  • Smooth Muscle Myocytes 76%
  • Inflammation 51%
  • Phenotype 29%

• Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders

  Nievergelt, C. M., Maihofer, A. X., Atkinson, E. G., Chen, C-Y., Choi, K. W., Coleman, J. R., Daskalakis, N. P., Duncan, L. E., Polimanti, R., Aaronson, C., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegoviç, E., Babic, D., Bacanu, S-A., Baker, D. G., & 215 othersBatzler, A., Beckham, J. C., Belangero, S., Benjet, C., Bergner, C., Bierer, L. M., Biernacka, J. M., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Brandolino, A., Breen, G., Bressan, R. A., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Børglum, A. D., Børte, S., Cahn, L., Calabrese, J. R., Caldas-de-Almeida, J. M., Chatzinakos, C., Cheema, S., Clouston, S. A. P., Colodro-Conde, L., Coombes, B. J., Cruz-Fuentes, C. S., Dale, A. M., Dalvie, S., Davis, L. K., Deckert, J., Delahanty, D. L., Dennis, M. F., deRoon-Cassini, T., Desarnaud, F., DiPietro, C. P., Disner, S. G., Docherty, A. R., Domschke, K., Dyb, G., Kulenovic, A. D., Edenberg, H. J., Evans, A., Fabbri, C., Fani, N., Farrer, L. A., Feder, A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C. F., Goci, A., Goleva, S. B., Gordon, S. D., Grasser, L. R., Guindalini, C., Haas, M., Hagenaars, S., Hauser, M. A., Heath, A. C., Hemmings, S. M., Hesselbrock, V., Hickie, I. B., Hogan, K., Hougaard, D. M., Huang, H., Huckins, L. M., Hveem, K., Jakovljevic, M., Javanbakht, A., Jenkins, G. D., Johnson, J., Jones, I., Jovanovic, T., Karstoft, K-I., Kaufman, M. L., Kennedy, J. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kotov, R., Kranzler, H. R., Krebs, K., Kremen, W. S., Kuan, P-F., Lawford, B. R., Lebois, L. A. M., Lehto, K., Levey, D. F., Lewis, C., Liberzon, I., Linnstaedt, S. D., Logue, M. W., Lori, A., Lu, Y., Luft, B. J., Lupton, M. K., Luykx, J. J., Makotkine, I., Maples-Keller, J. L., Marchese, S., Marmar, C., Martin, N. G., MartÍnez-Levy, G. A., McAloney, K., McFarlane, A., McLaughlin, K. A., McLean, S. A., Medland, S. E., Mehta, D., Meyers, J., Michopoulos, V., Mikita, E. A., Milani, L., Milberg, W., Miller, M. W., Morey, R. A., Morris, C. P., Mors, O., Mortensen, P. B., Mufford, M. S., Nelson, E. C., Nordentoft, M., Norman, S. B., Nugent, N. R., O'Donnell, M., Orcutt, H. K., Pan, P. M., Panizzon, M. S., Pathak, G. A., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Porjesz, B., Powers, A., Qin, X-J., Ratanatharathorn, A., Risbrough, V. B., Roberts, A. L., Rothbaum, B. O., Rothbaum, A. O., Roy-Byrne, P., Ruggiero, K. J., Rung, A., Runz, H., Rutten, B. P. F., de Viteri, S. S., Salum, G. A., Sampson, L., Sanchez, S. E., Santoro, M., Seah, C., Seedat, S., Seng, J. S., Shabalin, A., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stensland, S., Stevens, J. S., Sumner, J. A., Teicher, M. H., Thompson, W. K., Tiwari, A. K., Trapido, E., Uddin, M., Ursano, R. J., Valdimarsdóttir, U., van den Heuvel, L. L., Van Hooff, M., van Rooij, S. J., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Z., Wang, Y., Waszczuk, M., Weber, H., Wendt, F. R., Werge, T., Williams, M. A., Williamson, D. E., Winsvold, B. S., Winternitz, S., Wolf, E. J., Wolf, C., Xia, Y., Xiong, Y., Yehuda, R., Young, R. M., Young, K. A., Zai, C. C., Zai, G. C., Zervas, M., Zhao, H., Zoellner, L. A., Zwart, J-A., Stein, M. B., Ressler, K. J. & Koenen, K. C., 2 Sept 2023, medRxiv.

  Research output: Working paper › Preprint › Academic

  • Neurobiology 100%
  • Post-Traumatic Stress Disorders 84%
  • TNF Receptor-Associated Factor 3 46%
  • Wounds and Injuries 41%
  • Axon Guidance 36%

• Estimation of introduction and transmission rates of SARS-CoV-2 in a prospective household study

  van Boven, M., van Dorp, C. H., Westerhof, I., Jaddoe, V., Heuvelman, V., Duijts, L., Fourie, E., Sluiter-Post, J., van Houten, M. A., Badoux, P., Euser, S., Herpers, B., Eggink, D., de Hoog, M., Boom, T., Wildenbeest, J., Bont, L., Rozhnova, G., Bonten, M. J., Kretzschmar, M. E., & 1 othersBruijning-Verhagen, P., 5 Jun 2023, medRxiv, 21 p. (medRxiv).

  Research output: Working paper › Preprint › Academic

  File

  • SARS Virus 100%
  • Prospective Studies 43%
  • Child 14%
  • Vaccination 13%
  • Infectious Disease Transmission 10%
  2 Downloads (Pure)

• EV-Elute: a universal platform for enrichment of functional surface marker-defined extracellular vesicle subpopulations

  de Voogt, W., Frunt, R., Leandro, R., Triesscheijn, C., Monica, B., Paspali, I., Tielemans, M., Gitz-Francois, J. J. J. M., Seinen, CW., de Jong, O. & Kooijmans, S., 29 Oct 2023, BioRxiv, 28 p.

  Research output: Working paper › Preprint › Academic

  File

  • Extracellular Vesicles 100%
  • Phosphatidylserines 8%
  • Antibodies 7%
  • Endopeptidase K 4%
  • Proteins 3%
  4 Downloads (Pure)

• Evidence of survival bias in the association between APOE-ϵ4 and age of ischemic stroke onset.

  1 Dec 2023, medRxiv.

  Research output: Working paper › Preprint › Academic

  File

  • Age of Onset 100%
  • Stroke 72%
  • Genome-Wide Association Study 31%
  • Mortality 30%
  • Single Nucleotide Polymorphism 12%

• EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

  van de Kooij, B., Schreuder, A., Pavani, R. S., Garzero, V., Van Hoeck, A., San Martin Alonso, M., Koerse, D., Wendel, T. J., Callen, E., Boom, J., Mei, H., Cuppen, E., Nussenzweig, A., van Attikum, H. & Noordermeer, S. M., 24 Feb 2023, BioRxiv, p. 1-37, 37 p.

  Research output: Working paper › Preprint › Academic

  • DNA Repair 100%
  • Homologous Recombination 60%
  • Poly Adenosine Diphosphate Ribose 38%
  • Neoplasms 34%
  • Chromosomal Instability 33%

• Female gene networks are expressed in myofibroblast-like smooth muscle cells in vulnerable atherosclerotic plaques

  Benavente, E. D., Karnewar, S., Buono, M., Mili, E., Hartman, R. J. G., Kapteijn, D., Slenders, L., Daniels, M., Aherrahrou, R., Reinberger, T., Mol, B. M., de Borst, G. J., de Kleijn, D. P. V., Prange, K. H. M., Depuydt, M. A. C., de Winther, M. P. J., Kuiper, J., Bj Rkegren, J. L. M., Erdmann, J., Civelek, M., & 4 othersMokry, M., Owens, G. K., Pasterkamp, G. & den Ruijter, H. M., 9 Feb 2023, BioRxiv.

  Research output: Working paper › Preprint › Academic

  File

  • Myofibroblasts 100%
  • Gene Regulatory Networks 94%
  • Atherosclerotic Plaques 91%
  • Smooth Muscle Myocytes 76%
  • Atherosclerosis 40%
  18 Downloads (Pure)

• IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering

  Karnewar, S., Karnewar, V., Deaton, R., Shankman, L. S., Benavente, E. D., Williams, C. M., Bradley, X., Alencar, G. F., Bulut, G. B., Kirmani, S., Baylis, R. A., Zunder, E. R., den Ruijter, H. M., Pasterkamp, G. & Owens, G. K., 14 Oct 2023, BioRxiv.

  Research output: Working paper › Preprint › Academic

  Open Access

  • Interleukin-1 100%
  • Smooth Muscle Myocytes 88%
  • Western Diet 80%
  • Diet 68%
  • Lipids 65%

• Integrative multi-ancestry genetic analysis of gene regulation in coronary arteries prioritizes disease risk loci

  Hodonsky, C. J., Turner, A. W., Khan, M. D., Barrientos, N. B., Methorst, R., Ma, L., Lopez, N. G., Mosquera, J. V., Auguste, G., Farber, E., Ma, W. F., Wong, D., Onengut-Gumuscu, S., Kavousi, M., Peyser, P. A., van der Laan, S. W., Leeper, N. J., Kovacic, J. C., Björkegren, J. L. M. & Miller, C. L., 14 Feb 2023, medRxiv.

  Research output: Working paper › Preprint › Academic

  File

  • Coronary Artery Disease 100%
  • Genome-Wide Association Study 75%
  • Coronary Vessels 59%
  • Genes 48%
  • Quantitative Trait Loci 30%
  4 Downloads (Pure)

• Lack of association between HLA and asymptomatic SARS-CoV-2 infection

  8 Dec 2023, BMJ, (medRxiv).

  Research output: Working paper › Preprint › Academic

  File

  • SARS Virus 100%
  • HLA-B Antigens 43%
  • Infections 32%
  • Human Genetics 27%
  • Alleles 24%
  8 Downloads (Pure)

• Leukocytes carrying Clonal Hematopoiesis of Indeterminate Potential (CHIP) Mutations invade Human Atherosclerotic Plaques.

  von Scheidt, M., Bauer, S., Ma, A., Hao, K., Kessler, T., Vilne, B., Wang, Y., Hodonsky, C. J., Ghosh, S. K. B., Mokry, M., Gao, H., Kawai, K., Sakamoto, A., Kaiser, J., Bongiovanni, D., Fleig, J., Oldenbuettel, L., Chen, Z., Moggio, A., Sager, H. B., & 14 othersHecker, J. S., Bassermann, F., Maegdefessel, L., Miller, C. L., Koenig, W., Zeiher, A. M., Dimmeler, S., Graw, M., Braun, C., Ruusalepp, A., Leeper, N. J., Kovacic, J. C., Björkegren, J. L. M. & Schunkert, H., 26 Jul 2023, medRxiv, 34 p.

  Research output: Working paper › Preprint › Academic

  File

  • Hematopoiesis 100%
  • Atherosclerotic Plaques 95%
  • Leukocytes 72%
  • Mutation 51%
  • Macrophages 17%
  3 Downloads (Pure)

• Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5T MR-Linear accelerator hybrid system: A prospective R-IDEAL Stage 2a imaging biomarker characterization/ pre-qualification study

  5 May 2023, (medRxiv).

  Research output: Working paper › Preprint › Academic

  • Particle Accelerators 100%
  • Head and Neck Neoplasms 75%
  • Magnetic Resonance Spectroscopy 63%
  • Kinetics 54%
  • Biomarkers 49%

• Microvascular Specificity of Spin Echo BOLD fMRI: Impact of EPI Echo Train Length

  van Horen, T., Siero, J. C. W., Bhogal, A. A., Petridou, N. & Báez-Yáñez, M. G., 15 Sept 2023, BioRxiv, (bioRxiv).

  Research output: Working paper › Preprint › Academic

  File

  • Veins 100%
  • Echo-Planar Imaging 82%
  • Magnetic Resonance Imaging 79%
  • Hyperoxia 74%
  • Pulse 67%
  3 Downloads (Pure)

• Normative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization

  2 Dec 2023, BioRxiv.

  Research output: Working paper › Preprint › Academic

  Open Access

  • Statistical Models 100%
  • Benchmarking 96%
  • Longevity 79%
  • Brain 43%
  • Neuroimaging 40%

• Online speech synthesis using a chronically implanted brain-computer interface in an individual with ALS

  Angrick, M., Luo, S., Rabbani, Q., Candrea, D. N., Shah, S., Milsap, G. W., Anderson, W. S., Gordon, C. R., Rosenblatt, K. R., Clawson, L., Maragakis, N., Tenore, F. V., Fifer, M. S., Hermansky, H., Ramsey, N. F. & Crone, N. E., 1 Jul 2023, medRxiv, p. 1-30, 30 p.

  Research output: Working paper › Preprint › Academic

  File

• Pathogenic variants in SMARCA1 cause an X-linked neurodevelopmental disorder modulated by NURF complex composition

  Picketts, D., Mirzaa, G., Yan, K., Relator, R., Timpano, S., Yalcin, B., Collins, S., Ziegler, A., Pao, E., Oyama, N., Brischoux-Boucher, E., Piard, J., Monaghan, K., Sacoto, M. G., Dobyns, W., Park, K., Fernández-Mayoralas, D., Fernández-Jaén, A., Jayakar, P., Brusco, A., & 42 othersAntona, V., Giorgio, E., Kvarnung, M., Isidor, B., Conrad, S., Cogné, B., Deb, W., Stuurman, K. E., Sterbova, K., Smal, N., Weckhuysen, S., Oegema, R., Innes, M., Latsko, M., Ben-Omran, T., Yeh, R., Kruer, M., Bakhtiari, S., Papavasiliou, A., Moutton, S., Nambot, S., Chanprasert, S., Paolucci, S., Miller, K., Burton, B., Kim, K., O'Heir, E., Bruwer, Z., Donald, K., Kleefstra, T., Goldstein, A., Angle, B., Bontempo, K., Miny, P., Joset, P., Demurger, F., Hobson, E., Pang, L., Carpenter, L., Li, D., Bonneau, D. & Sadikovic, B., 29 Sept 2023, Research Square, 32 p. (Research square).

  Research output: Working paper › Preprint › Academic

  File

  • Neurodevelopmental Disorders 100%
  • Chromatin Assembly and Disassembly 49%
  • Megalencephaly 30%
  • Maternal Inheritance 27%
  • Penetrance 24%
  4 Downloads (Pure)

• Precise Spatial Tuning of Visually Driven Alpha Oscillations in Human Visual Cortex

  Yuasa, K., Groen, I. I. A., Piantoni, G., Montenegro, S., Flinker, A., Devore, S., Devinsky, O., Doyle, W., Dugan, P., Friedman, D., Ramsey, N., Petridou, N. & Winawer, J., 12 Jul 2023, BioRxiv, p. 1-40.

  Research output: Working paper › Preprint › Academic

  • Visual Cortex 100%
  • Psychological Power 89%
  • Arousal 47%
  • Implanted Electrodes 29%
  • Occipital Lobe 25%

• Proteogenomic integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis

  Prapiadou, S., Živković, L., Thorand, B., George, M. J., van der Laan, S. W., Malik, R., Herder, C., Koenig, W., Ueland, T., Kleveland, O., Aukrust, P., Gullestad, L., Bernhagen, J., Pasterkamp, G., Peters, A., Hingorani, A. D., Rosand, J., Dichgans, M., Anderson, C. D. & Georgakis, M. K., 28 Mar 2023, (medRxiv).

  Research output: Working paper › Preprint › Academic

  Open Access

  File

  • Proteogenomics 100%
  • Atherosclerosis 48%
  • Interleukin-6 46%
  • Interleukin-6 Receptors 33%
  • Proteomics 23%
  5 Downloads (Pure)

• Rare disease gene association discovery from burden analysis of the 100,000 Genomes Project data

  Cipriani, V., Vestito, L., Magavern, E. F., Jacobsen, J. O., Arno, G., Behr, E. R., Benson, K. A., Bertoli, M., Bockenhauer, D., Bowl, M. R., Burley, K., Chan, L. F., Chinnery, P., Conlon, P., Costa, M., Davidson, A. E., Dawson, S. J., Elhassan, E., Flanagan, S. E., Futema, M., & 41 othersGale, D. P., García-Ruiz, S., Corcia, C. G., Griffin, H. R., Hambleton, S., Hicks, A. R., Houlden, H., Houlston, R. S., Howles, S. A., Kleta, R., Lekkerkerker, I., Lin, S., Liskova, P., Mitchison, H., Morsy, H., Mumford, A. D., Newman, W. G., Neatu, R., O'Toole, E. A., Ong, A. C., Pagnamenta, A. T., Rahman, S., Rajan, N., Robinson, P. N., Ryten, M., Sadeghi-Alavijeh, O., Sayer, J. A., Shovlin, C. L., Taylor, J. C., Teltsh, O., Tomlinson, I., Tucci, A., Turnbull, C., van Eerde, A. M., Ware, J. S., Watts, L. M., Webster, A. R., Westbury, S. K., Zheng, S. L., Caulfield, M. & Smedley, D., 21 Dec 2023, medRxiv, 42 p. (medRxiv).

  Research output: Working paper › Preprint › Academic

• RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma

  Randolph, M. E., Afifi, M., Gorthi, A., Weil, R., Wilky, B. A., Weinreb, J., Ciero, P., Ter Hoeve, N., van Diest, P. J., Raman, V., Bishop, A. J. R. & Loeb, D. M., 10 Jun 2023, BioRxiv, p. 1-40.

  Research output: Working paper › Preprint › Academic

  File

  • RNA Helicases 100%
  • Ewing's Sarcoma 87%
  • DNA Repair 66%
  • DNA Damage 62%
  • Cytoplasm 29%
  12 Downloads (Pure)

• Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People with Type 2 Diabetes Mellitus

  Kwak, S. H., Hernandez-Cancela, R. B., DiCorpo, D. A., Condon, D. E., Merino, J., Wu, P., Brody, J. A., Yao, J., Guo, X., Ahmadizar, F., Meyer, M., Sincan, M., Mercader, J. M., Lee, S., Haessler, J., Vy, H. M. T., Lin, Z., Armstrong, N. D., Gu, S., Tsao, N. L., & 47 othersLange, L. A., Wang, N., Wiggins, K. L., Trompet, S., Liu, S., Loos, R. J. F., Judy, R., Schroeder, P. H., Hasbani, N. R., Bos, M. M., Morrison, A. C., Jackson, R. D., Reiner, A. P., Manson, J. E., Chaudhary, N. S., Carmichael, L. K., Chen, Y-D. I., Taylor, K. D., Ghanbari, M., van Meurs, J., Pitsillides, A. N., Psaty, B. M., Noordam, R., Do, R., Park, K. S., Jukema, J. W., Kavousi, M., Correa, A., Rich, S. S., Damrauer, S. M., Hajek, C., Cho, N. H., Irvin, M. R., Pankow, J. S., Nadkarni, G. N., Sladek, R., Goodarzi, M. O., Florez, J. C., Chasman, D. I., Heckbert, S. R., Kooperberg, C., Dupuis, J., Malhotra, R., de Vries, P. S., Liu, C-T., Rotter, J. I. & Meigs, J. B., 28 Jul 2023, medRxiv, p. 1-37, 37 p.

  Research output: Working paper › Preprint › Academic

  File

  • Genome-Wide Association Study 100%
  • Type 2 Diabetes Mellitus 71%
  • Cardiovascular Diseases 69%
  • Coronary Artery Disease 21%
  • Confidence Intervals 20%
  7 Downloads (Pure)
• 2021

  Sex-dependent gene regulation of human atherosclerotic plaques by DNA methylation and transcriptome integration points to smooth muscle cell involvement in women

  Hartman, R., Siemelink, M., Haitjema, S., Dekkers, K. F., Slenders, L., Boltjes, A., Mokry, M., Timmerman, N., De Borst, G. J., Heijmans, B. T., Asselbergs, F. W., Pasterkamp, G., Van der Laan, S. W. & Den Ruijter, H. M., 29 Jan 2021, BioRxiv.

  Research output: Working paper › Preprint › Academic

  • Atherosclerotic Plaques 100%
  • DNA Methylation 94%
  • Transcriptome 88%
  • Smooth Muscle Myocytes 84%
  • Sex Characteristics 51%
• 2020

  Birthweight by gestational age reference centile charts for Greek neonates

  Tsagkari, A., Pateras, K., Ladopoulou, D., Kornarou, E. & Vlachadis, N., 4 Oct 2020, medRxiv.

  Research output: Working paper › Preprint › Academic

  File
• 2019

  Design of the EPIGENEC Study: Assessing the EPIdemiology and GENetics of Escherichia coli in the Netherlands

  van Hout, D., Verschuuren, T., Bruijning-Verhagen, P., Bosch, T., Reuland, A., Fluit, AC., Schürch, A., Willems, R., de Greeff, S. C., van 't Veen, A., Kluijtmans, J. & Bonten, M., 7 Feb 2019, (Preprints).

  Research output: Working paper › Preprint › Academic

  File

  • Molecular Epidemiology 100%
  • Netherlands 82%
  • Escherichia coli 59%
  • Community-Acquired Infections 30%
  • Escherichia coli Infections 29%