Infectious Diseases Research 4

Research output

Research output per year 1992 1998 1999 2007 2015 2016 2021 2022 2023 2024

• 68 Article
• 3 Review article
• 1 Chapter
• 1 Doctoral thesis 1 (Research UU / Graduation UU)

Research output per year

Research output per year

Search results

• 2024

  Host and environmental factors shape upper airway microbiota and respiratory health across the human lifespan

  Odendaal, M. L., de Steenhuijsen Piters, W. A. A., Franz, E., Chu, M. L. J. N., Groot, J. A., van Logchem, E. M., Hasrat, R., Kuiling, S., Pijnacker, R., Mariman, R., Trzciński, K., van der Klis, F. R. M., Sanders, E. A. M., Smit, L. A. M., Bogaert, D. & Bosch, T., 22 Aug 2024, In: Cell. 187, 17, p. 4571-4585.e15

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

• Impact of age on pneumococcal colonization of the nasopharynx and oral cavity: an ecological perspective

  Miellet, W. R., Mariman, R., van Veldhuizen, J., Badoux, P., Wijmenga-Monsuur, A. J., Litt, D., Bosch, T., Miller, E., Fry, N. K., van Houten, M. A., Rots, N. Y., Sanders, E. A. M. & Trzciński, K., Jan 2024, In: ISME communications. 4, 1, 9 p., ycae002.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Nasopharynx 100%
  • Serogroup 77%
  • Mouth 72%
  • Saliva 68%
  • Streptococcus pneumoniae 28%
  1 Downloads (Pure)
• 2023

  A spitting image: molecular diagnostics applied to saliva enhance detection of Streptococcus pneumoniae and pneumococcal serotype carriage

  Miellet, W. R., van Veldhuizen, J., Litt, D., Mariman, R., Wijmenga-Monsuur, A. J., Nieuwenhuijsen, T., Christopher, J., Thombre, R., Eletu, S., Bosch, T., Rots, N. Y., van Houten, M. A., Miller, E., Fry, N. K., Sanders, E. A. M. & Trzciński, K., 17 Apr 2023, In: Frontiers in Microbiology. 14, 13 p., 1156695.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Molecular Pathology 100%
  • Streptococcus pneumoniae 89%
  • Saliva 85%
  • Serogroup 79%
  • Polymerase Chain Reaction 40%

• Meningococcal carriage in children and young adults: a cross-sectional and longitudinal study, Iceland, 2019 to 2021

  Kristinsdottir, I., Visser, L. J., Miellet, W. R., Mariman, R., Pluister, G., Haraldsson, G., Haraldsson, A., Trzciński, K. & Thors, V., 28 Sept 2023, In: Eurosurveillance. 28, 39, 2300215.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Iceland 100%
  • Neisseria meningitidis 89%
  • colonization 78%
  • cross-sectional study 72%
  • Icelander 61%
  5 Downloads (Pure)

• Saliva as an alternative sample type for detection of pneumococcal carriage in young children

  Wyllie, A. L., Rots, N. Y., Wijmenga-Monsuur, A. J., van Houten, M. A., Sanders, E. A. M. & Trzciński, K., Oct 2023, In: Microbiology. 169, 10, p. 1-8 8 p., 001394.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Saliva 100%
  • Child 44%
  • Streptococcus pneumoniae 26%
  • Serogroup 23%
  • Sampling Studies 16%
  4 Downloads (Pure)

• Streptococcus pneumoniae carriage studies in adults: Importance, challenges, and key issues to consider when using quantitative PCR-based approaches

  Miellet, W., Almeida, S. T., Trzciński, K. & Sá-Leão, R., 16 Feb 2023, In: Frontiers in Microbiology. 14, 8 p., 1122276.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Streptococcus pneumoniae 100%
  • Polymerase Chain Reaction 57%
  • Serotyping 25%
  • Pneumococcal Vaccines 24%
  • Conjugate Vaccines 24%
  10 Downloads (Pure)

• Surveillance of Neisseria meningitidis carriage four years after menACWY vaccine implementation in the Netherlands reveals decline in vaccine-type and rise in genogroup e circulation

  Miellet, W. R., Pluister, G., Sikking, M., Tappel, M., Karczewski, J., Visser, L. J., Bosch, T., Trzciński, K. & Mariman, R., 31 Jul 2023, In: Vaccine. 41, 34, p. 4927-4932 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Neisseria meningitidis 100%
  • Netherlands 72%
  • surveillance 64%
  • vaccines 64%
  • Vaccines 56%
• 2022

  Approximate likelihood-based estimation method of multiple-type pathogen interactions: An application to longitudinal pneumococcal carriage data

  Man, I., Bogaards, J. A., Makwana, K., Trzciński, K. & Auranen, K., 15 Mar 2022, In: Statistics in Medicine. 41, 6, p. 981-993 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Clearance 100%
  • Serogroup 94%
  • Likelihood 90%
  • Interaction 74%
  • Acquisition 66%
  7 Downloads (Pure)

• High Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Household Transmission Rates Detected by Dense Saliva Sampling

  Kolodziej, L. M., van Lelyveld, S. F. L., Haverkort, M. E., Mariman, R., Sluiter-Post, J. G. C., Badoux, P., de Koff, E. M., Koole, J. C. D., Miellet, W. R., Swart, A. N., Coipan, E. C., Meijer, A., Sanders, E. A. M., Trzciński, K., Euser, S. M., Eggink, D. & van Houten, M. A., 1 Jul 2022, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 75, 1, p. e10-e19

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Saliva 75%
  • Whole Genome Sequencing 9%
  • Pandemics 8%

• It Takes Two to Tango: Combining Conventional Culture With Molecular Diagnostics Enhances Accuracy of Streptococcus pneumoniae Detection and Pneumococcal Serogroup/Serotype Determination in Carriage

  Miellet, W. R., van Veldhuizen, J., Litt, D., Mariman, R., Wijmenga-Monsuur, A. J., Badoux, P., Nieuwenhuijsen, T., Thombre, R., Mayet, S., Eletu, S., Sheppard, C., van Houten, M. A., Rots, N. Y., Miller, E., Fry, N. K., Sanders, E. A. M. & Trzciński, K., 18 Apr 2022, In: Frontiers in Microbiology. 13, 859736.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Molecular Pathology 100%
  • Streptococcus pneumoniae 89%
  • Serogroup 79%
  • ROC Curve 14%
  • Vaccines 13%
  10 Downloads (Pure)

• Pneumococcal carriage in unvaccinated children at the time of vaccine implementation into the national immunization program in Poland

  7 Apr 2022, In: Scientific Reports. 12, 1, 5858.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Immunization Programs 100%
  • Poland 92%
  • Serogroup 76%
  • Vaccines 62%
  • Child 36%

• Pneumococcal genetic variability in age-dependent bacterial carriage

  Kremer, P. H. C., Ferwerda, B., Bootsma, H. J., Rots, N. Y., Wijmenga-Monsuur, A. J., Sanders, E. A. M., Trzciński, K., Wyllie, A. L., Turner, P., van der Ende, A., Brouwer, M. C., Bentley, S. D., van de Beek, D. & Lees, J. A., 26 Jul 2022, In: eLife. 2022, 11, p. 1-20 e69244.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Serogroup 100%
  • Molecular Cluster 71%
  • Glycoprotein 50%
  • Genome 44%
  • Strain 38%
  12 Downloads (Pure)
• 2021

  Detection of Neisseria meningitidis in saliva and oropharyngeal samples from college students

  Miellet, W. R., Mariman, R., Pluister, G., de Jong, L. J., Grift, I., Wijkstra, S., van Logchem, E. M., van Veldhuizen, J., Immink, M. M., Wijmenga-Monsuur, A. J., Rots, N. Y., Sanders, E. A. M., Bosch, T. & Trzciński, K., 30 Nov 2021, In: Scientific Reports. 11, 1, p. 1-9 23138.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Neisseria meningitidis 100%
  • Saliva 79%
  • Students 56%
  • MenACWY 49%
  • Genotype 38%
  10 Downloads (Pure)

• Examining the Distribution and Impact of Single-Nucleotide Polymorphisms in the Capsular Locus of Streptococcus pneumoniae Serotype 19A

  Arends, D. W., Miellet, W. R., Langereis, J. D., Ederveen, T. H. A., van der Gaast–de Jongh, C. E., van Scherpenzeel, M., Knol, M. J., van Sorge, N. M., Lefeber, D. J., Trzcinski, K., Sanders, E. A. M., Dorfmueller, H. C., Bootsma, H. J. & de Jonge, M. I., 15 Oct 2021, In: Infection and Immunity. 89, 11, p. 1-14 e00246-21.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Streptococcus pneumoniae 100%
  • single nucleotide polymorphism 74%
  • Serogroup 73%
  • Capsules 71%
  • serotypes 68%
  1 Citation (Scopus)

  14 Downloads (Pure)

• Influenza-like Illness Exacerbates Pneumococcal Carriage in Older Adults

  Miellet, W. R., Van Veldhuizen, J., Nicolaie, M. A., Mariman, R., Bootsma, H. J., Bosch, T., Rots, N. Y., Sanders, E. A. M., Van Beek, J. & Trzciński, K., 1 Nov 2021, In: Clinical Infectious Diseases. 73, 9, p. E2680-E2689

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Human Influenza 100%
  • Saliva 35%
  • Streptococcus pneumoniae 24%
  • Confidence Intervals 21%
  • Rhinovirus 15%
  1 Citation (Scopus)

  9 Downloads (Pure)
• 2019

  Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

  Lees, J. A., Ferwerda, B., Kremer, P. H. C., Wheeler, N. E., Serón, M. V., Croucher, N. J., Gladstone, R. A., Bootsma, H. J., Rots, N. Y., Wijmega-Monsuur, A. J., Sanders, E. A. M., Trzciński, K., Wyllie, A. L., Zwinderman, A. H., van den Berg, L. H., van Rheenen, W., Veldink, J. H., Harboe, Z. B., Lundbo, L. F., de Groot, L. C. P. G. M., & 20 othersvan Schoor, N. M., van der Velde, N., Ängquist, L. H., Sørensen, T. I. A., Nohr, E. A., Mentzer, A. J., Mills, T. C., Knight, J. C., du Plessis, M., Nzenze, S., Weiser, J. N., Parkhill, J., Madhi, S., Benfield, T., von Gottberg, A., van der Ende, A., Brouwer, M. C., Barrett, J. C., Bentley, S. D. & van de Beek, D., 15 May 2019, In: Nature Communications. 10, 1, 2176.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • meningitis 100%
  • Pneumococcal Meningitis 71%
  • pathogens 69%
  • sequencing 67%
  • genome 64%
  3 Citations (Scopus)

  11 Downloads (Pure)

• Visie op toekomstige surveillance van respiratoire bacteriële pathogenen

  Mariman, R., Bosch, T., Miellet, W., Pluister, G. N., van Veldhuizen, J., Sanders, E. & Trzcinski, K., 2019, In: Nederlands tijdschrift voor medische microbiologie. 27, 4, p. 217-220

  Research output: Contribution to journal › Article › Academic › peer-review
• 2018

  Distribution of serotypes and patterns of antimicrobial resistance among commensal Streptococcus pneumoniae in nine European countries

  Yahiaoui, R. Y., Bootsma, H. J., den Heijer, C. D. J., Pluister, G. N., John Paget, W., Spreeuwenberg, P., Trzcinski, K. & Stobberingh, E. E., 29 Aug 2018, In: BMC Infectious Diseases. 18, 1, p. 1-10 440.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Streptococcus pneumoniae 100%
  • Serogroup 89%
  • Nose 17%
  • Penicillin Resistance 15%
  • Conjugate Vaccines 13%
  2 Downloads (Pure)

• Exploring immune development in infants with moderate to severe atopic dermatitis

  Hulshof, L., Overbeek, S. A., Wyllie, A. L., Chu, M. L. J. N., Bogaert, D., de Jager, W., Knippels, L. M. J., Sanders, E. A. M., van Aalderen, W. M. C., Garssen, J., van't Land, B. & Sprikkelman, A. B., 29 Mar 2018, In: Frontiers in Immunology. 9, 630.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Atopic Dermatitis 100%
  • Child Development 99%
  • Chemokine CCL22 43%
  • Chemokine CCL17 42%
  • Chemokines 38%
  1 Downloads (Pure)

• The relative invasive disease potential of Streptococcus pneumoniae among children after PCV introduction: A systematic review and meta-analysis

  Balsells, E., Dagan, R., Yildirim, I., Gounder, P. P., Steens, A., Muñoz-Almagro, C., Mameli, C., Kandasamy, R., Givon Lavi, N., Daprai, L., van der Ende, A., Trzciński, K., Nzenze, S. A., Meiring, S., Foster, D., Bulkow, L. R., Rudolph, K., Valero-Rello, A., Ducker, S., Vestrheim, D. F., & 9 othersvon Gottberg, A., Pelton, S. I., Zuccotti, G. V., Pollard, A. J., Sanders, E. A. M., Campbell, H., Madhi, S. A., Nair, H. & Kyaw, M. H., 1 Nov 2018, In: Journal of Infection. 77, 5, p. 368-378 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Pneumococcal Vaccines 100%
  • Conjugate Vaccines 99%
  • Pneumococcal Infections 84%
  • Streptococcus pneumoniae 81%
  • Serogroup 73%
  1 Citation (Scopus)
• 2017

  Sequencing of the variable region of rpsB to discriminate between Streptococcus pneumoniae and other streptococcal species

  Wyllie, A. L., Pannekoek, Y., Bovenkerk, S., van Engelsdorp Gastelaars, J., Ferwerda, B., van de Beek, D., Sanders, E. A. M., Trzciński, K. & van der Ende, A., Sept 2017, In: Open Biology. 7, 9

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Streptococcus pneumoniae 100%
  • Molecular Cluster 63%
  • Streptococcus 60%
  • Genome 39%
  • Pneumococcal Meningitis 28%
• 2016

  Carriage of Streptococcus pneumoniae in asymptomatic, community-dwelling elderly in the Netherlands

  van Deursen, AMM., van den Bergh, M. R. & Sanders, E. A. M., 2 Jan 2016, In: Vaccine. 34, 1, p. 4-6 3 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Streptococcus pneumoniae 100%
  • Independent Living 82%
  • Netherlands 78%
  • Elderly 54%
  • respiratory system 43%

• Dried saliva spots: A robust method for detecting Streptococcus pneumoniae carriage by PCR

  Krone, C. L., Oja, A. E., van de Groep, K., Sanders, E. A. M., Bogaert, D. & Trzcinski, K., 5 Mar 2016, In: International journal of molecular sciences. 17, 3, 343.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • pneumonia 100%
  • streptococcus 97%
  • saliva 91%
  • carriages 91%
  • Desiccant 86%
  1 Citation (Scopus)

• Dysbiosis of upper respiratory tract microbiota in elderly pneumonia patients

  de Steenhuijsen Piters, W. A. A., Huijskens, E. G. W., Wyllie, A. L., Biesbroek, G., van den Bergh, M. R., Veenhoven, R. H., Wang, X., Trzcinski, K., Bonten, M. J., Rossen, J. W. A., Sanders, E. A. M. & Bogaert, D., Jan 2016, In: ISME Journal. 10, 1, p. 97-108

  Research output: Contribution to journal › Article › Academic › peer-review

  • dysbiosis 100%
  • pneumonia 84%
  • Dysbiosis 81%
  • respiratory tract 79%
  • respiratory system 70%

• Molecular surveillance of nasopharyngeal carriage of Streptococcus pneumoniae in children vaccinated with conjugated polysaccharide pneumococcal vaccines

  Wyllie, A. L., Wijmenga-Monsuur, A. J., van Houten, M. A., Bosch, A. A. T. M., Groot, J. A., van Engelsdorp Gastelaars, J., Bruin, J. P., Bogaert, D., Rots, N. Y., Sanders, E. A. M. & Trzciński, K., 5 Apr 2016, In: Scientific Reports. 6, 23809.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Pneumococcal Vaccines 100%
  • Streptococcus pneumoniae 81%
  • Serogroup 73%
  • Child 34%
  • Vaccines 26%

• Molecular surveillance on Streptococcus pneumoniae carriage in non-elderly adults; little evidence for pneumococcal circulation independent from the reservoir in children

  Wyllie, A. L., Rümke, L. W., Arp, K., Bosch, A. A. T. M., Bruin, J. P., Rots, N. Y., Wijmenga-Monsuur, A. J., Sanders, E. A. M. & Trzciński, K., 7 Oct 2016, In: Scientific Reports. 6, 9 p., 34888.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Streptococcus pneumoniae 100%
  • Serogroup 89%
  • Parents 49%
  • Child 42%
  • Vaccines 24%
  1 Downloads (Pure)

• Nasopharyngeal carriage of Streptococcus pneumoniae and other bacteria in the 7th year after implementation of the pneumococcal conjugate vaccine in the Netherlands

  Bosch, A. A. T. M., van Houten, M. A., Bruin, J. P., Wijmenga-Monsuur, A. J., Trzciński, K., Bogaert, D., Rots, N. Y. & Sanders, E. A. M., 20 Jan 2016, In: Vaccine. 34, 4, p. 531-539 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Streptococcus pneumoniae 100%
  • Pneumococcal Vaccines 99%
  • Conjugate Vaccines 99%
  • Netherlands 78%
  • vaccines 69%
  10 Citations (Scopus)

  2 Downloads (Pure)
• 2015

  Carriage of Streptococcus pneumoniae in aged adults with influenza-like-illness

  Krone, C. L., Wyllie, A. L., van Beek, J., Rots, N. Y., Oja, A. E., Chu, M. L. J. N., Bruin, J. P., Bogaert, D., Sanders, E. A. M. & Trzcinski, K., 2015, In: PLoS ONE [E]. 10, 3, p. e0119875

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Streptococcus pneumoniae 100%
  • Human Influenza 90%
  • Saliva 68%
  • Elderly 56%
  • Serogroup 51%

• Development of the Nasopharyngeal Microbiota in Infants with Cystic Fibrosis

  Prevaes, S. M. P. J., de Winter-de Groot, K. M., Janssens, H. M., de Steenhuijsen Piters, W. A. A., Tramper-Stranders, G. A., Wyllie, A. L., Hasrat, R., Tiddens, H. A., van Westreenen, M., van der Ent, C. K., Sanders, E. A. M. & Bogaert, D., 2015, In: American Journal of Respiratory and Critical Care Medicine.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Microbiota 100%
  • Cystic Fibrosis 98%
  • Moraxella 80%
  • Corynebacterium 67%
  • Streptococcus mitis 51%

• Effect of Serotype on Pneumococcal Competition in a Mouse Colonization Model.

  Trzcinski, KP., 15 Aug 2015, In: MBio [E]. 6, 5

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Serogroup 100%
  • Capsules 56%
  • Nasopharyngeal Diseases 27%
  • Pneumococcal Infections 19%
  • Genetic Background 16%
  1 Downloads (Pure)

• Identification of pneumococcal colonization determinants in the stringent response pathway facilitated by genomic diversity

  Trzcinski, KP., 2015, In: BMC Genomics. 16, 369.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Neutrophils 100%
  • Genes 64%
  • Phenotype 57%
  • Genome 43%
  • Whole Genome Sequencing 37%

• Salivary antibody levels in adolescents in response to a meningococcal serogroup C conjugate booster vaccination nine years after priming: systemically induced local immunity and saliva as potential surveillance tool

  Stoof, S. P., van der Klis, F. R. M., van Rooijen, D. M., Bogaert, D., Trzcinski, K., Sanders, E. A. M. & Berbers, G. A. M., 31 Jul 2015, In: Vaccine. 33, 32, p. 3933-9 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • secondary immunization 100%
  • immunity 76%
  • vaccination 75%
  • saliva 69%
  • Saliva 66%
• 2010

  MYBBP1A: a new Ipr1's binding protein in mice.

  Trzcinski, KP., 2010, In: Molecular Biology Reports.

  Research output: Contribution to journal › Article › Academic › peer-review

• Re-emergence of the type 1 pilus among Streptococcus pneumoniae isolates in Massachusetts, USA

  Regev-Yochay, G., Hanage, W. P., Trzcinski, K., Rifas-Shiman, S. L., Lee, G., Bessolo, A., Huang, S. S., Pelton, S. I., McAdam, A. J., Finkelstein, J. A., Lipsitch, M. & Malley, R., 1 Jul 2010, In: Vaccine. 28, 30, p. 4842-4846 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Streptococcus pneumoniae 100%
  • fimbriae 95%
  • vaccination 89%
  • candidacy 60%
  • Vaccines 60%
  39 Citations (Scopus)
• 2009

  Killing niche competitors by remote-control bacteriophage induction

  Selva, L., Viana, D., Regev-Yochay, G., Trzcinski, K., Corpa, J. M., Lasa, Í., Novick, R. P. & Penadés, J. R., 27 Jan 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 4, p. 1234-1238 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Genetics SOS Response 100%
  • Streptococcus pneumoniae 71%
  • Bacteriophages 69%
  • Prophages 64%
  • Antibiosis 37%
  83 Citations (Scopus)
• 2008

  Protection against nasopharyngeal colonization by Streptococcus pneumoniae is mediated by antigen-specific CD4⁺ T cells

  Trzciński, K., Thompson, C. M., Srivastava, A., Basset, A., Malley, R. & Lipsitch, M., 1 Jun 2008, In: Infection and Immunity. 76, 6, p. 2678-2684 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • CD4 Antigens 100%
  • Streptococcus pneumoniae 98%
  • T-lymphocytes 72%
  • Cholera Toxin 62%
  • Vaccines 59%
  71 Citations (Scopus)
• 2007

  Association of the pneumococcal pilus with certain capsular serotypes but not with increased virulence

  Basset, A., Trzcinski, K., Hermos, C., O'Brien, K. L., Reid, R., Santosham, M., McAdam, A. J., Lipsitch, M. & Malley, R., 1 Jun 2007, In: Journal of Clinical Microbiology. 45, 6, p. 1684-1689 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Pneumococcal Vaccines 100%
  • Serogroup 73%
  • Virulence 70%
  • Conjugate Vaccines 66%
  • North American Indians 65%
  64 Citations (Scopus)

• SpxB is a suicide gene of Streptococcus pneumoniae and confers a selective advantage in an in vivo competitive colonization model

  Regev-Yochay, G., Trzcinski, K., Thompson, C. M., Lipsitch, M. & Malley, R., 1 Sept 2007, In: Journal of Bacteriology. 189, 18, p. 6532-6539 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Streptococcus pneumoniae 100%
  • Suicide 90%
  • Genes 39%
  • amidase 24%
  • Autolysis 23%
  73 Citations (Scopus)

• Strain characteristics of Streptococcus pneumoniae carriage and invasive disease isolates during a cluster-randomized clinical trial of the 7-valent pneumococcal conjugate vaccine

  Lipsitch, M., O'Neill, K., Cordy, D., Bugalter, B., Trzcinski, K., Thompson, C. M., Goldstein, R., Pelton, S., Huot, H., Bouchet, V., Reid, R., Santosham, M. & O'Brien, K. L., 22 Oct 2007, In: Journal of Infectious Diseases. 196, 8, p. 1221-1227 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Pneumococcal Vaccines 100%
  • Conjugate Vaccines 99%
  • Streptococcus pneumoniae 81%
  • Serogroup 73%
  • Randomized Controlled Trials 54%
  52 Citations (Scopus)
• 2006

  Evidence for tetracycline resistance determinant tet(M) allele replacement in a Streptococcus pneumoniae population of limited geographical origin

  Dzieranowska-Fangrat, K., Semczuk, K., Górska, P., Giedrys-Kalemba, S., Kochman, M., Samet, A., Tyski, S., Dzieranowska, D. & Trzciński, K., 1 Feb 2006, In: International Journal of Antimicrobial Agents. 27, 2, p. 159-164 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Tetracycline Resistance 100%
  • Tetracycline 76%
  • Multiple Drug Resistance 75%
  • Streptococcus pneumoniae 73%
  • Alleles 53%
  8 Citations (Scopus)

• Incremental increase in fitness cost with increased β-lactam resistance in pneumococci evaluated by competition in an infant rat nasal colonization model

  Trzciński, K., Thompson, C. M., Gilbey, A. M., Dowson, C. G. & Lipsitch, M., 1 May 2006, In: Journal of Infectious Diseases. 193, 9, p. 1296-1303 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Lactams 100%
  • Streptococcus pneumoniae 71%
  • Penicillins 70%
  • Nose 56%
  • Costs and Cost Analysis 43%
  42 Citations (Scopus)

• Interference between Streptococcus pneumoniae and Staphylococcus aureus: In vitro hydrogen peroxide-mediated killing by Streptococcus pneumoniae

  Regev-Yochay, G., Trzciński, K., Thompson, C. M., Malley, R. & Lipsitch, M., 1 Jul 2006, In: Journal of Bacteriology. 188, 13, p. 4996-5001 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Streptococcus pneumoniae 100%
  • Hydrogen Peroxide 98%
  • Pyruvate Oxidase 90%
  • Staphylococcus aureus 84%
  • Catalase 47%
  115 Citations (Scopus)
• 2005

  Antibodies to conserved pneumococcal antigens correlate with, but are not required for, protection against pneumococcal colonization induced by prior exposure in a mouse model

  Trzciński, K., Thompson, C., Malley, R. & Lipsitch, M., 1 Oct 2005, In: Infection and Immunity. 73, 10, p. 7043-7046 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • exposure models 100%
  • animal models 55%
  • antigens 47%
  • antibodies 41%
  • Antigens 40%
  55 Citations (Scopus)

• Capsule homology does not increase the frequency of transformation of linked penicillin binding proteins PBP 1a and PBP 2x in Streptococcus pneumoniae

  Trzciński, K., MacNeil, A., Klugman, K. P. & Lipsitch, M., 1 Apr 2005, In: Antimicrobial Agents and Chemotherapy. 49, 4, p. 1591-1592 2 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Penicillin-Binding Proteins 100%
  • Penicillin Resistance 99%
  • Streptococcus pneumoniae 72%
  • Capsules 64%
  • Serogroup 32%
  2 Citations (Scopus)

• CD4⁺ T cells mediate antibody-independent acquired immunity to pneumococcal colonization

  Malley, R., Trzcinski, K., Srivastava, A., Thompson, C. M., Anderson, P. W. & Lipsitch, M., 29 Mar 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 13, p. 4848-4853 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Adaptive Immunity 100%
  • T-Lymphocytes 60%
  • Streptococcus pneumoniae 60%
  • Antibodies 54%
  • Immunization 49%
  259 Citations (Scopus)
• 2004

  Single-step capsular transformation and acquisition of penicillin resistance in Streptococcus pneumoniae

  Trzciński, K., Thompson, C. M. & Lipsitch, M., 1 Jun 2004, In: Journal of Bacteriology. 186, 11, p. 3447-3452 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Lactams 100%
  • Penicillin Resistance 97%
  • Streptococcus pneumoniae 71%
  • Capsules 41%
  • Serogroup 32%
  30 Citations (Scopus)
• 2003

  Construction of Otherwise Isogenic Serotype 6B, 7F, 14, and 19F Capsular Variants of Streptococcus pneumoniae Strain TIGR4

  Trzciński, K., Thompson, C. M. & Lipsitch, M., 1 Dec 2003, In: Applied and Environmental Microbiology. 69, 12, p. 7364-7370 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • pneumonia 100%
  • Streptococcus pneumoniae 95%
  • polysaccharide 80%
  • Polysaccharides 72%
  • Serogroup 70%
  62 Citations (Scopus)
• 2000

  Expression of resistance to tetracyclines in strains of methicillin-resistant Staphylococcus aureus

  Trzcinski, K., Cooper, B. S., Hryniewicz, W. & Dowson, C. G., 1 Jan 2000, In: Journal of Antimicrobial Chemotherapy. 45, 6, p. 763-770 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Tetracycline Resistance 100%
  • Minocycline 90%
  • Methicillin-Resistant Staphylococcus aureus 73%
  • Tetracycline 66%
  • Doxycycline 52%
  167 Citations (Scopus)

• Genetic diversity of the tet(M) gene in tetracycline-resistant clonal lineages of Streptococcus pneumoniae

  Doherty, N., Trzcinski, K., Pickerill, P., Zawadzki, P. & Dowson, C. G., 9 Nov 2000, In: Antimicrobial Agents and Chemotherapy. 44, 11, p. 2979-2984 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Tetracycline 100%
  • Streptococcus pneumoniae 96%
  • Genetic Variation 91%
  • Serogroup 86%
  • Clone Cells 75%
  101 Citations (Scopus)

• Oporne na metycyline szczepy Staphylococcus aureus izolowane od chorych w Państwowym Szpitalu Klinicznym Nr 2 w Szczecinie.

  Translated title of the contribution: Methicillin resistant clinical strains of Staphylococcus aureus isolated from patients in the State Clinical Hospital Nr 2 in SzczecinBilska, I., Giedrys-Kalemba, S., Murchan, S. & Trzciński, K., 1 Jan 2000, In: Medycyna doświadczalna i mikrobiologia. 52, 3, p. 229-236 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • State Hospitals 100%
  • Methicillin Resistance 96%
  • Staphylococcus aureus 68%
  • Methicillin-Resistant Staphylococcus aureus 61%
  • Poland 22%
  1 Citation (Scopus)