Division of Heart & Lungs

Research output

Research output per year 1983 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2024

• 6533 Article
• 365 Review article
• 314 Doctoral thesis 1 (Research UU / Graduation UU)
• 299 Meeting Abstract
• 983 More
  • 271 Chapter
  • 182 Comment/Letter to the editor
  • 93 Letter
  • 92 Editorial
  • 65 Other contribution
  • 58 Poster
  • 52 Abstract
  • 34 Literature review
  • 28 Doctoral thesis 2 (Research NOT UU / Graduation UU)
  • 23 Conference contribution
  • 15 Patent
  • 14 Book editing
  • 13 Book
  • 10 Short survey
  • 8 Preprint
  • 7 Inaugural speech
  • 7 Doctoral thesis 3 (Research UU / Graduation NOT UU)
  • 5 Report
  • 3 Paper
  • 2 Digital or Visual Products
  • 1 Foreword/postscript

Research output per year

Research output per year

Search results

• 2024

  Advanced diagnostics and novel therapeutic strategies in ischemic heart disease

  van Klarenbosch, B., 10 Sept 2024, Utrecht: Utrecht University. 200 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

• Antithrombotic therapy in patients with suspected ST-segment elevation myocardial infarction

  Vogel, R. F., 1 Oct 2024, Utrecht: Utrecht University. 285 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

• Cellular substrates of arrhythmogenicity in inherited and acquired cardiomyopathies

  van Ham, W., 11 Apr 2024, Utrecht: Utrecht University. 221 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cardiomyopathies 100%
  • Cardiac Arrhythmias 28%
  • Interdisciplinary Research 23%
  • Psychological Handling 21%
  • Heart Diseases 13%
  18 Downloads (Pure)

• Clinical pharmacology of CFTR modulators

  van der Meer, R., 15 Feb 2024, Utrecht University. 162 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  • Clinical Pharmacology 100%
  • Cystic Fibrosis 81%
  • Pharmaceutical Preparations 19%
  • Organoids 16%
  • ivacaftor drug combination lumacaftor 15%

• Early changes in heart failure with preserved ejection fraction: The merit of a sex-specific approach

  van Ommen, A-M., 15 Oct 2024, Utrecht University. 274 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

• Explainable artificial intelligence for the electrocardiogram

  van de Leur, R. R., 10 Oct 2024, Utrecht University. 330 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

• Harmonizing Heartbeats: A translational approach towards preventing life-threatening ventricular arrhythmias

  Loen, V., 30 May 2024, Utrecht University. 211 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cardiac Arrhythmias 100%
  • Implantable Defibrillators 55%
  • Torsades de Pointes 18%
  • Atrioventricular Block 16%
  • Swine 10%
  1 Downloads (Pure)

• Integrating omics for an improved understanding of cardiac diseases

  van Vugt, M., 4 Jun 2024, Utrecht: Utrecht University. 200 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Heart Diseases 100%
  • Heart Failure 90%
  • Atrial Fibrillation 87%
  • Cardiomyopathies 72%
  • Proteins 45%
  4 Downloads (Pure)

• Optimization of percutaneous coronary intervention using new stent designs and individualized antiplatelet therapy

  van Hemert, N., 13 Sept 2024, Utrecht University. 198 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

• Potentials of Stem Cell derived cardiomyocytes: 'From disease modelling to therapeutic strategies'

  Maas, R. G., 13 Mar 2024, Utrecht: Utrecht University. 414 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cardiomyopathies 100%
  • Cardiac Myocytes 95%
  • Stem Cells 75%
  • Induced Pluripotent Stem Cells 52%
  • Heart 18%
  4 Downloads (Pure)

• Progressive Pulmonary Fibrosis in Connective Tissue Disease

  Chiu, Y-H., 2 Jul 2024, Utrecht University. 154 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Connective Tissue Diseases 100%
  • Pulmonary Fibrosis 95%
  • Interstitial Lung Diseases 79%
  • Biomarkers 40%
  • Systemic Scleroderma 35%

• Propafenone's Impact on KIR2.1 Channel Modulation and the Quest for Safe Alternatives

  Li, E., 9 Oct 2024, Utrecht University. 214 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

• Towards Clinical Implementation of Deformation Imaging in Genetic Cardiomyopathies

  Kirkels, F., 11 Jun 2024, Utrecht University. 236 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cardiomyopathies 100%
  • Arrhythmogenic Right Ventricular Dysplasia 71%
  • Sudden Cardiac Death 56%
  • Cardiac Arrhythmias 43%
  • Automation 31%
• 2023

  A Quest for Non-Invasive Biomarkers in Arrhythmogenic and Phospholamban Cardiomyopathy: New Tools to Facilitate Diagnosis, Prognosis and Prediction

  van der Voorn, S., 23 Nov 2023, Utrecht University. 224 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • phospholamban 100%
  • Cardiomyopathies 68%
  • Biomarkers 45%
  • Cardiac Arrhythmias 26%
  • Heart 24%
  6 Downloads (Pure)

• BIG DATA to understand BIG HEARTS: Unravelling the molecular mechanisms in hypertrophic cardiomyopathy

  Wright Clark, M., 28 Mar 2023, Utrecht University. 170 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Hypertrophic Cardiomyopathy 100%
  • Heart 56%
  • Sarcomeres 55%
  • Penetrance 50%
  • Mutation 49%
  2 Downloads (Pure)

• Cardiac MRI in arrhythmogenic right ventricular cardiomyopathy: Implementation of novel techniques

  Bourfiss, M., 8 Jun 2023, Utrecht: Utrecht University. 344 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Cardiomyopathies 69%
  • Early Diagnosis 28%
  • Genetic Techniques 23%
  • Cardiac Volume 22%
  6 Downloads (Pure)

• Clinical aspects and treatment options in non-CF bronchiectasis

  Terpstra, L., 18 Dec 2023, Utrecht University. 208 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Bronchiectasis 100%
  • Macrolides 37%
  • Placebos 22%
  • Inhalation 15%
  • Therapeutics 13%
  12 Downloads (Pure)

• Cystic Fibrosis: a real-world challenge to predict individual outcomes

  Muilwijk, D., 27 Oct 2023, Utrecht: Utrecht University. 253 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cystic Fibrosis 100%
  • Cystic Fibrosis Transmembrane Conductance Regulator 85%
  • Disease Progression 27%
  • Patient Reported Outcome Measures 18%
  • Colforsin 18%
  22 Downloads (Pure)

• Data-driven innovation of left ventricular assist device therapy

  Numan, L., 23 Nov 2023, Utrecht University. 206 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Heart-Assist Devices 100%
  • Heart Failure 20%
  • Therapeutics 13%
  • Heart 12%
  • Transplants 11%
  16 Downloads (Pure)

• Drug and device testing in a preclinical model sensitive to cardiac arrhythmias

  van Bavel, J., 28 Sept 2023, Utrecht: Utrecht University. 228 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cardiac Arrhythmias 100%
  • Equipment and Supplies 70%
  • Atrioventricular Block 69%
  • Cardiac Electrophysiology 58%
  • Pharmaceutical Preparations 48%
  10 Downloads (Pure)

• Engineering Extracellular Vesicles for Protein-based Drug Delivery

  Ilahibaks, N., 19 Jun 2023, Utrecht University. 264 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  • Extracellular Vesicles 100%
  • Pharmaceutical Preparations 35%
  • Proteins 31%
  • Nanomedicine 9%
  • Tacrolimus Binding Protein 1A 6%

• Extracellular Vesicle Heterogeneity and its Translational Implications for Cardiac Repair

  van de Wakker, S., 15 Dec 2023, Utrecht University. 236 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  • Extracellular Vesicles 100%
  • Chromatography 16%
  • Field Flow Fractionation 10%
  • Therapeutics 6%
  • Regenerative Medicine 6%

• Generalizability of Randomized Controlled Trials in Heart Failure

  Lim Mei Fong, Y., 27 Sept 2023, Utrecht University. 228 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Heart Failure 100%
  • Randomized Controlled Trials 92%
  • Registries 86%
  • Population 53%
  • Heart 53%
  18 Downloads (Pure)

• MANAGEMENT OF RHEUMATIC HEART DISEASE IN LOW-TO-MIDDLE-INCOME COUNTRY

  Meidian Ambari, A., 29 Aug 2023, Utrecht University. 165 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Rheumatic Heart Disease 100%
  • Income 62%
  • Balloon Valvuloplasty 43%
  • Mitral Valve 31%
  • Mitral Valve Stenosis 31%
  51 Downloads (Pure)

• Non-invasive Fractional Flow Reserve and Antiplatelet Therapy in Cardiac Interventions: An Epidemiological Perspective

  Peper, J., 23 May 2023, Utrecht University. 295 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Ticagrelor 100%
  • Chest Pain 68%
  • Transplants 44%
  • Clopidogrel 40%
  • Workflow 38%

• Novel Frontiers in Sarcomeric Cardiomyopathies: Biomarkers, Early Detection and Prognosis

  Jansen, M., 19 Dec 2023, Utrecht University. 257 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Hypertrophic Cardiomyopathy 100%
  • Cardiomyopathies 96%
  • Biomarkers 64%
  • Penetrance 63%
  • Pedigree 24%
  46 Downloads (Pure)

• Rheumatic heart disease in Tanzania: insight in clinical aspects and outcome

  Mutagaywa, R., 29 Aug 2023, Utrecht: Utrecht University. 254 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Rheumatic Heart Disease 100%
  • Tanzania 91%
  • Endocarditis 19%
  • Mortality 15%
  • Mitral Valve 12%
  15 Downloads (Pure)

• Sarcoidosis Associated Pulmonary Hypertension: An exploratory journey

  Huitema, M., 11 May 2023, Utrecht University. 234 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Sarcoidosis 100%
  • Pulmonary Hypertension 91%
  • Pulmonary Artery 11%
  • Ventricular Pressure 8%
  • Cardiac Catheterization 8%
  9 Downloads (Pure)

• Systemic and tissue neutrophil responses to experimental trauma

  Teuben, M., 16 Jan 2023, Global Academic Press. 300 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Neutrophils 100%
  • Wounds and Injuries 61%
  • Neutrophil Activation 17%
  • Fracture Healing 16%
  • Fracture Fixation 16%
  18 Downloads (Pure)

• The Application of Non-invasive Inverse ECG Techniques in Cardiomyopathy

  Boonstra, M., 21 Jun 2023, Utrecht University. 226 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Electrocardiography 100%
  • Chemical activation 32%
  • Lead 20%
  • Electrodes 11%
  • Magnetic resonance imaging 7%
  19 Downloads (Pure)

• The applications of single-cell RNA sequencing in atherosclerotic research

  Slenders, L., 28 Mar 2023, Utrecht: Utrecht University. 216 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • RNA Sequence Analysis 100%
  • Smooth Muscle Myocytes 32%
  • Endothelial Cells 19%
  • Genome-Wide Association Study 16%
  • Population 14%
  8 Downloads (Pure)

• Therapeutic RNA regulation during cardiac remodeling and disease

  Vigil-Garcia, M., 16 Feb 2023, Utrecht University. 128 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Heart Diseases 100%
  • RNA 85%
  • Hydrogels 75%
  • Genes 49%
  • Cardiac Myocytes 49%
  16 Downloads (Pure)

• Therapeutic strategies to rescue damaged heart

  Fang, J., 18 Sept 2023, Utrecht: Utrecht University. 280 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  • Heart Failure 100%
  • Heart 88%
  • Cardiac Myocytes 84%
  • Polyploidy 57%
  • Genetic Therapy 42%
• 2022

  Colchicine in coronary disease: Using the available to enable the sustainable

  Fiolet, ATL., 24 Feb 2022, Utrecht University. 419 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Colchicine 100%
  • Coronary Disease 76%
  • Pragmatic Clinical Trials 61%
  • Atherosclerosis 35%
  • Anti-Inflammatory Agents 31%
  20 Downloads (Pure)

• Coronary Artery Disease: Inflammatory Pathways and Interventions

  Silvis, M., 7 Apr 2022, Utrecht University. 291 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Coronary Artery Disease 100%
  • Anti-Inflammatory Agents 35%
  • Myocardial Infarction 35%
  • Inflammasomes 28%
  • Coronary Sinus 28%
  21 Downloads (Pure)

• Disease management of chronic heart failure

  Brons, M., 8 Dec 2022, Utrecht University. 151 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Disease Management 100%
  • Heart Failure 73%
  • Critical Pathways 31%
  • Amyloidosis 30%
  • Natriuretic Peptides 11%
  2 Downloads (Pure)

• Electronic Health Record Data in Cardiovascular Research

  Sammani, A., 10 May 2022, Utrecht University. 211 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Artificial intelligence 100%
  • Health 83%
  • Big data 68%
  • Statistical Models 34%
  • Pipelines 28%
  19 Downloads (Pure)

• Electrophysiological Methods for Early Detection and Risk Stratification in Arrhythmogenic Cardiomyopathy

  Roudijk, R., 12 Apr 2022, Utrecht University. 276 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cardiomyopathies 100%
  • Electrocardiography 83%
  • Ventricular Tachycardia 54%
  • Bundle-Branch Block 30%
  • Sudden Cardiac Death 28%
  19 Downloads (Pure)

• Enhancing quality in translation research - learning from experiences in cardiac repair

  van der Naald, M., 27 Sept 2022, Utrecht University. 520 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Learning 100%
  • Biomedical Research 27%
  • Research Personnel 19%
  • Anniversaries and Special Events 17%
  • Translational Medical Research 15%
  8 Downloads (Pure)

• Extracellular Vesicles for risk stratification in coronary artery disease: Trash or Treasure

  Dekker, M., 17 Mar 2022, Utrecht University. 200 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Extracellular Vesicles 100%
  • Coronary Artery Disease 70%
  • Coronary Vessels 17%
  • Deep Learning 14%
  • Perfusion Imaging 12%
  9 Downloads (Pure)

• Extracellular vesicle therapeutics: from mechanism to application in cardiac repair

  Roefs, M. T., 28 Nov 2022, Utrecht University. 234 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Extracellular Vesicles 100%
  • Therapeutics 13%
  • Myocardium 8%
  • Stem Cells 7%
  • Heart 6%
  2 Downloads (Pure)

• Idiopathic ventricular fibrillation: Absence of evidence is not evidence of absence

  Groeneveld, S., 1 Dec 2022, Utrecht University. 160 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Paroxysmal ventricular fibrillation 100%
  • Sudden Cardiac Death 19%
  • Ventricular Fibrillation 15%
  • Mitral Valve 14%
  • Software Design 5%
  29 Downloads (Pure)

• Irreversible electroporation for cardiac ablation: from preclinical research to clinical application

  Groen, M., 21 Apr 2022, Utrecht: Utrecht University. 158 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Electroporation 100%
  • Electrodes 62%
  • Catheters 32%
  • Electric Impedance 31%
  • Gases 17%
  9 Downloads (Pure)

• Patient-Tailored Cardiac Resynchronization Therapy: Imaging and Exercise Strategies

  Wouters, P., 24 Nov 2022, Utrecht: Utrecht University. 261 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cardiac Resynchronization Therapy 100%
  • Exercise 53%
  • Lead 37%
  • Stress Echocardiography 26%
  • Exercise Tolerance 24%
  2 Downloads (Pure)

• Personalized Medicine in Arrhythmogenic Right Ventricular Cardiomyopathy

  Bosman, L., 22 Feb 2022, Utrecht University. 288 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Precision Medicine 76%
  • Sudden Cardiac Death 51%
  • Advisory Committees 33%
  • Cardiac Arrhythmias 33%
  8 Downloads (Pure)

• Point-of-care fully automated flow cytometry: From cell biology to clinical decision-making in trauma surgery

  Spijkerman, R., 8 Feb 2022, Utrecht University. 296 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Point-of-Care Systems 100%
  • Clinical Decision-Making 93%
  • Cell Biology 76%
  • Flow Cytometry 67%
  • Wounds and Injuries 43%
  8 Downloads (Pure)

• Prediction models, machine learning and missing data

  Nijman, S., 7 Jun 2022, Utrecht University. 191 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Machine learning 100%
  • Data handling 29%
  • Personalized medicine 17%
  • Calibration 9%
  11 Downloads (Pure)

• Telomere shortening and fibrotic remodeling in progressive fibrosing interstitial lung disease

  van Batenburg, A., 30 Jun 2022, Utrecht University. 169 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Telomere Shortening 100%
  • Interstitial Lung Diseases 82%
  • Telomere 74%
  • Lung 32%
  • DNA Damage 26%
  2 Downloads (Pure)

• The Clinical Utility of Deformation Imaging in Early Arrhythmogenic Cardiomyopathy

  Taha, K., 24 May 2022, Utrecht University. 276 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cardiomyopathies 100%
  • Cardiac Arrhythmias 26%
  • Myocardium 17%
  • Penetrance 11%
  • Sudden Cardiac Death 11%
  2 Downloads (Pure)

• Therapeutic strategies and prognosis in aortic coarctation: a lifelong disease

  Meijs, T., 30 Jun 2022, Utrecht University. 216 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Aortic Coarctation 100%
  • Stents 68%
  • Thoracic Aorta 53%
  • Epinephrine 24%
  • Exercise 17%
  4 Downloads (Pure)