Department of Experimental Pulmonary Diseases

Research output

Research output per year 1985 1993 2017 2018 2019 2020 2021 2024

• 189 Article
• 21 Review article
• 13 Doctoral thesis 1 (Research UU / Graduation UU)
• 8 Comment/Letter to the editor
• 8 More
  • 3 Letter
  • 2 Meeting Abstract
  • 2 Editorial
  • 1 Doctoral thesis 2 (Research NOT UU / Graduation UU)

Research output per year

Research output per year

Search results

• 2024

  Accurate Placement and Revisions for Cervical Pedicle Screws Placed With or Without Navigation: A Systematic Review and Meta-Analysis

  Bindels, B. J. J., Dronkers, B. E. G., Smits, M. L. J. & Verlaan, J. J., Apr 2024, In: Global Spine Journal. 14, 3, p. 1018-1037 20 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Pedicle Screws 100%
  • Meta-Analysis 60%
  • Systematic Reviews 59%
  • Learning Curve 11%
  • Postoperative Complications 8%
  1 Downloads (Pure)

• Automated, Point-of-Care mobile flow cytometry: Bringing the laboratory to the sample

  Jukema, B. N., Pelgrim, T. C., Spoelder, M., Bongers, C. C. W. G., Hopman, M. T. E., Smit, K., Rijk, M. H., Venekamp, R. P., Vrisekoop, N. & Koenderman, L., 30 Apr 2024, In: Heliyon. 10, 8, p. 1-13 13 p., e28883.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Point-of-Care Systems 100%
  • Flow Cytometry 67%
  • Hospital Laboratories 37%
  • Eosinophils 28%
  • Monocytes 24%

• Extramedullary neutrophil progenitors: Quo Vadis?

  Koenderman, L. & Vrisekoop, N., 2024, In: Cellular and Molecular Immunology. 21, 8, p. 932–934 3 p.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

• Identification of neutrophil phenotype categories in geriatric hip fracture patients aids in personalized medicine

  Nijdam, T. M. P., Jukema, B. N., de Fraiture, E. J., Spijkerman, R., Schuijt, H. J., Spoelder, M., Bongers, C. C. W. G., Hopman, M. T. E., Koenderman, L., Hietbrink, F. & van der Velde, D., Jan 2024, In: OTA international : the open access journal of orthopaedic trauma. 7, 1S, p. 1-6 6 p., e291.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Precision Medicine 100%
  • Hip Fractures 99%
  • Geriatrics 88%
  • Neutrophils 72%
  • Phenotype 55%
  4 Downloads (Pure)

• Point-of-care neutrophil and monocyte surface markers differentiate bacterial from viral infections at the emergency department within 30 min

  Jukema, B. N., de Hond, T. A. P., Kroon, M., Maranus, A. E., Koenderman, L. & Kaasjager, K. A. H., Apr 2024, In: Journal of Leukocyte Biology. 115, 4, p. 714-722 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Point-of-Care Systems 100%
  • Bacterial Infections 82%
  • Monocytes 73%
  • Hospital Emergency Service 71%
  • Neutrophils 69%
  4 Downloads (Pure)

• Surface CD52, CD84, and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donors

  Pettinella, F., Mariotti, B., Lattanzi, C., Bruderek, K., Donini, M., Costa, S., Marini, O., Iannoto, G., Gasperini, S., Caveggion, E., Castellucci, M., Calzetti, F., Bianchetto-Aguilera, F., Gardiman, E., Giani, M., Dusi, S., Cantini, M., Vassanelli, A., Pavone, D., Milella, M., & 15 othersPilotto, S., Biondani, P., Höing, B., Schleupner, M. C., Hussain, T., Hadaschik, B., Kaspar, C., Visco, C., Tecchio, C., Koenderman, L., Bazzoni, F., Tamassia, N., Brandau, S., Cassatella, M. A. & Scapini, P., 20 Feb 2024, In: Cell Reports Medicine. 5, 2, 101380.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Receptors, Prostaglandin E, EP2 Subtype 100%
  • RNA Sequencing 95%
  • Prostaglandin E 90%
  • Myeloid-Derived Suppressor Cells 77%
  • Granulocyte Colony-Stimulating Factor 61%
• 2023

  Comprehensive multivariate evaluation of the effects on cell phenotypes in multicolor flow cytometry data using ANOVA simultaneous component analysis

  Bertinetto, C. G., Spijkerman, R., Hesselink, L., Tinnevelt, G. H., Bongers, C. C. W. G., Postma, G. J., Hopman, M. T. E., Koenderman, L. & Jansen, J. J., Jul 2023, In: Journal of Chemometrics. 37, 7, 17 p., e3402.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Flow Cytometry 100%
  • Flow cytometry 93%
  • Phenotype 75%
  • Cytometry 65%
  • Analysis of variance (ANOVA) 64%
  7 Downloads (Pure)

• Eosinophils—from cradle to grave

  Jesenak, M., Diamant, Z., Simon, D., Tufvesson, E., Seys, S. F., Mukherjee, M., Lacy, P., Vijverberg, S., Slisz, T., Sediva, A., Simon, H. U., Striz, I., Plevkova, J., Schwarze, J., Kosturiak, R., Alexis, N. E., Untersmayr, E., Vasakova, M. K., Knol, E. & Koenderman, L., Dec 2023, In: Allergy: European Journal of Allergy and Clinical Immunology. 78, 12, p. 3077-3102 26 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Eosinophils 100%
  • Homeostasis 16%
  • Adjustment Disorders 15%
  • Biological Products 11%
  • Antiviral Agents 9%

• Exercise-induced eosinophil responses: Normal cell counts with a marked decrease in responsiveness

  Jukema, B. N., Pelgrim, T. C., Janssen, S. L. J. E., Eijsvogels, T. M. H., Mingels, A., Vroemen, W., Vrisekoop, N. & Koenderman, L., Nov 2023, In: Clinical and Translational Allergy. 13, 11, 3 p., e12314.

  Research output: Contribution to journal › Letter › Academic › peer-review

  Open Access

  File
  14 Downloads (Pure)

• Family participation in essential care activities in adult intensive care units: An integrative review of interventions and outcomes

  Dijkstra, B. M., Felten-Barentsz, K. M., van der Valk, M. J. M., Pelgrim, T., van der Hoeven, J. G., Schoonhoven, L., Ebben, R. H. A. & Vloet, L. C. M., Sept 2023, In: Journal of Clinical Nursing. 32, 17-18, p. 5904-5922 19 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Intensive Care Units 100%
  • Health Care Outcome Assessment 31%
  • Mental Health 18%
  • Pressure Ulcer 14%
  • Delirium 13%

• N⁶-Methyladenosine Directly Regulates CD40L Expression in CD4⁺ T Lymphocytes

  van Vroonhoven, E. C. N., Picavet, L. W., Scholman, R. C., van den Dungen, N. A. M., Mokry, M., Evers, A., Lebbink, R. J., Calis, J. J. A., Vastert, S. J. & van Loosdregt, J., Jul 2023, In: Biology. 12, 7, 11 p., 1004.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • N(6)-methyladenosine 100%
  • CD40 Ligand 78%
  • T-lymphocytes 57%
  • ligands 57%
  • T-Lymphocytes 39%
  5 Downloads (Pure)

• Nuclear segmentation facilitates neutrophil migration

  Shen, C., Mulder, E., Buitenwerf, W., Postat, J., Jansen, A., Kox, M., Mandl, J. N. & Vrisekoop, N., 1 Jun 2023, In: Journal of cell science. 136, 11, 7 p., jcs260768.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Neutrophils 100%
  • Confined Spaces 25%
  • Emergency Responders 22%
  • Lab-On-A-Chip Devices 21%
  • Neutrophil Infiltration 18%
  8 Downloads (Pure)

• Point-of-care neutrophil CD64 as a rule in diagnostic test for bacterial infections in the emergency department

  van de Ven, N. L. M., Bongers, S. H., Spijkerman, R., Koenderman, L., Leenen, L. P. H. & Hietbrink, F., 14 Mar 2023, In: BMC Emergency Medicine. 23, 1, p. 1-10 10 p., 28.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Point-of-Care Systems 100%
  • Routine Diagnostic Tests 83%
  • Bacterial Infections 82%
  • Hospital Emergency Service 71%
  • Neutrophils 69%
  14 Downloads (Pure)

• Quality over quantity; eosinophil activation status will deepen the insight into eosinophilic diseases

  Hilvering, B. & Koenderman, L., Feb 2023, In: Respiratory Medicine. 207, 107094.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Eosinophils 100%
  • Asthma 20%
  • Parasitic Diseases 9%
  • Acute Disease 9%
  • Therapeutics 7%
  20 Downloads (Pure)

• Systemic and tissue neutrophil responses to experimental trauma

  Teuben, M., 16 Jan 2023, Global Academic Press. 300 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Neutrophils 100%
  • Wounds and Injuries 61%
  • Neutrophil Activation 17%
  • Fracture Healing 16%
  • Fracture Fixation 16%
  15 Downloads (Pure)

• Visualization of the inflammatory response to injury by neutrophil phenotype categories: Neutrophil phenotypes after trauma

  de Fraiture, E. J., Bongers, S. H., Jukema, B. N., Koenderman, L., Vrisekoop, N., van Wessem, K. J. P., Leenen, L. P. H. & Hietbrink, F., Apr 2023, In: European Journal of Trauma and Emergency Surgery. 49, 2, p. 1023-1034 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Neutrophils 100%
  • Phenotype 76%
  • Wounds and Injuries 61%
  • Point-of-Care Systems 47%
  • Injury Severity Score 16%
  1 Downloads (Pure)
• 2022

  Dragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy

  Korenblik, R., Olij, B., Aldrighetti, L. A., Hilal, M. A., Ahle, M., Arslan, B., van Baardewijk, L. J., Baclija, I., Bent, C., Bertrand, C. L., Björnsson, B., de Boer, M. T., de Boer, S. W., Bokkers, R. P. H., Rinkes, I. H. M. B., Breitenstein, S., Bruijnen, R. C. G., Bruners, P., Büchler, M. W., Camacho, J. C., & 101 othersCappelli, A., Carling, U., Chan, B. K. Y., Chang, D. H., Choi, J., Font, J. C., Crawford, M., Croagh, D., Cugat, E., Davis, R., De Boo, D. W., De Cobelli, F., De Wispelaere, J. F., van Delden, O. M., Delle, M., Detry, O., Díaz-Nieto, R., Dili, A., Erdmann, J. I., Fisher, O., Fondevila, C., Fretland, Å., Borobia, F. G., Gelabert, A., Gérard, L., Giuliante, F., Gobardhan, P. D., Gómez, F., Grünberger, T., Grünhagen, D. J., Guitart, J., Hagendoorn, J., Heil, J., Heise, D., Herrero, E., Hess, G. F., Hoffmann, M. H., Iezzi, R., Imani, F., Nguyen, J., Jovine, E., Kalff, J. C., Kazemier, G., Kingham, T. P., Kleeff, J., Kollmar, O., Leclercq, W. K. G., Ben, S. L., Lucidi, V., MacDonald, A., Madoff, D. C., Manekeller, S., Martel, G., Mehrabi, A., Mehrzad, H., Meijerink, M. R., Menon, K., Metrakos, P., Meyer, C., Moelker, A., Modi, S., Montanari, N., Navines, J., Neumann, U. P., Peddu, P., Primrose, J. N., Qu, X., Raptis, D., Ratti, F., Ridouani, F., Rogan, C., Ronellenfitsch, U., Ryan, S., Sallemi, C., Moragues, J. S., Sandström, P., Sarriá, L., Schnitzbauer, A., Serenari, M., Serrablo, A., Smits, M. L. J., Sparrelid, E., Spüntrup, E., Stavrou, G. A., Sutcliffe, R. P., Tancredi, I., Tasse, J. C., Udupa, V., Valenti, D., Fundora, Y., Vogl, T. J., Wang, X., White, S. A., Wohlgemuth, W. A., Yu, D., Zijlstra, I. A. J., Binkert, C. A., Bemelmans, M. H. A., van der Leij, C., Schadde, E. & van Dam, R. M., Sept 2022, In: Cardiovascular and Interventional Radiology. 45, 9, p. 1391-1398 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Hepatic Veins 100%
  • Accreditation 97%
  • Manuscripts 96%
  • Portal Vein 84%
  • Hypertrophy 75%
  7 Downloads (Pure)

• Human neutrophil kinetics: a call to revisit old evidence

  Koenderman, L., Tesselaar, K. & Vrisekoop, N., Nov 2022, In: Trends in immunology. 43, 11, p. 868-876 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neutrophils 100%
  • Kinetics 92%
  • Longevity 32%
  • Bone Marrow 26%
  • Adaptive Immunity 18%

• Longitudinal assessment of the inflammatory response: The next step in personalized medicine after severe trauma

  de Fraiture, E. J., Vrisekoop, N., Leenen, L. P. H., van Wessem, K. J. P., Koenderman, L. & Hietbrink, F., 20 Sept 2022, In: Frontiers in medicine. 9, p. 1-9 983259.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Precision Medicine 100%
  • Neutrophils 72%
  • Wounds and Injuries 44%
  • Decision Making 21%
  • Biomarkers 17%
  9 Downloads (Pure)

• Neutrophil and Eosinophil Responses Remain Abnormal for Several Months in Primary Care Patients With COVID-19 Disease

  Jukema, B. N., Smit, K., Hopman, M. T. E., Bongers, C. C. W. G., Pelgrim, T. C., Rijk, M. H., Platteel, T. N., Venekamp, R. P., Zwart, D. L. M., Rutten, F. H. & Koenderman, L., 2022, In: Frontiers in allergy. 3, 942699.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Eosinophils 100%
  • Primary Health Care 81%
  • Neutrophils 80%
  • Neutrophil Activation 19%
  • Flow Cytometry 12%
  11 Downloads (Pure)

• Neutrophils Promote Glioblastoma Tumor Cell Migration after Biopsy

  Chen, N., Alieva, M., van der Most, T., Klazen, J. A. Z., Vollmann-Zwerenz, A., Hau, P. & Vrisekoop, N., 14 Jul 2022, In: Cells. 11, 14, p. 1-11 2196.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Glioblastoma 100%
  • Cell Movement 82%
  • Neutrophils 79%
  • Biopsy 61%
  • Environment 57%
  6 Downloads (Pure)

• Point-of-care fully automated flow cytometry: From cell biology to clinical decision-making in trauma surgery

  Spijkerman, R., 8 Feb 2022, Utrecht University. 296 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Point-of-Care Systems 100%
  • Clinical Decision-Making 93%
  • Cell Biology 76%
  • Flow Cytometry 67%
  • Wounds and Injuries 43%
  6 Downloads (Pure)

• Shift of Neutrophils From Blood to Bone Marrow Upon Extensive Experimental Trauma Surgery

  Teuben, M. P. J., Heeres, M., Blokhuis, T., Spijkerman, R., Knot, E., Vrisekoop, N., Pfeifer, R., Pape, H. C., Koenderman, L. & Leenen, L. P. H., 17 May 2022, In: Frontiers in Immunology. 13, p. 1-13 883863.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Neutrophils 100%
  • Bone Marrow 93%
  • Wounds and Injuries 61%
  • Cell Surface Receptors 10%
  • Neutropenia 9%
  6 Downloads (Pure)

• Standardized porcine unilateral femoral nailing is associated with changes in PMN activation status, rather than aberrant systemic PMN prevalence

  Jun 2022, In: European Journal of Trauma and Emergency Surgery. 48, 3, p. 1601-1611 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Granulocytes 100%
  • Thigh 81%
  • Swine 79%
  • Intramedullary Fracture Fixation 76%
  • Femur 38%
  4 Downloads (Pure)

• The journey of neutropoiesis: how complex landscapes in bone marrow guide continuous neutrophil lineage determination

  Overbeeke, C., Tak, T. & Koenderman, L., 14 Apr 2022, In: Blood. 139, 15, p. 2285-2293 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Apoptotic 100%
  • Clearance 94%
  • White 73%
  • Neutrophils 68%
  • Bone Marrow 63%
  1 Downloads (Pure)

• Three encephalitis-causing amoebae and their distinct interactions with the host

  Sarink, M. J., van der Meijs, N. L., Denzer, K., Koenderman, L., Tielens, A. G. M. & van Hellemond, J. J., Mar 2022, In: Trends in Parasitology. 38, 3, p. 230-245 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Amoeba 100%
  • Balamuthia mandrillaris 92%
  • encephalitis 92%
  • Encephalitis 81%
  • Acanthamoeba 72%

• Transformation of multicolour flow cytometry data with OTflow prevents misleading multivariate analysis results and incorrect immunological conclusions

  Folcarelli, R., van Staveren, S., Tinnevelt, G., Cadot, E., Vrisekoop, N., Buydens, L., Koenderman, L., Jansen, J. & van den Brink, O. F., Jan 2022, In: Cytometry Part A. 101, 1, p. 72-85 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Flow Cytometry 100%
  • Multivariate Analysis 93%
  • Artifacts 42%
  • Datasets 17%
  • Population 17%
  3 Downloads (Pure)
• 2021

  Analysis of human neutrophil phenotypes as biomarker to monitor exercise-induced immune changes

  Spijkerman, R., Hesselink, L., Bertinetto, C., Bongers, C. C. W. G., Hietbrink, F., Vrisekoop, N., Leenen, L. P. H., Hopman, M. T. E., Jansen, J. J. & Koenderman, L., Apr 2021, In: Journal of Leukocyte Biology. 109, 4, p. 833-842 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Neutrophils 100%
  • Biomarkers 83%
  • Phenotype 76%
  • Immune System 57%
  • Innate Immunity 50%
  10 Downloads (Pure)

• An increase in CD62Ldim neutrophils precedes the development of pulmonary embolisms in COVID-19 patients

  Spijkerman, R., Jorritsma, N. K., Bongers, S. H., Bindels, B. J., Jukema, B. N., Hesselink, L., Hietbrink, F., Leenen, L. P., van Goor, H. M., Vrisekoop, N., Kaasjager, K. A. & Koenderman, L., Jun 2021, In: Scandinavian Journal of Immunology. 93, 6, 8 p., e13023.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Pulmonary Embolism 100%
  • Neutrophils 79%
  • Virus Diseases 74%
  • Neutrophil Activation 15%
  • Phenotype 15%
  6 Downloads (Pure)

• CD5 levels define functionally heterogeneous populations of naïve human CD4+ T cells

  Sood, A., Lebel, M-È., Dong, M., Fournier, M., Vobecky, S. J., Haddad, É., Delisle, J-S., Mandl, J. N., Vrisekoop, N. & Melichar, H. J., Jun 2021, In: European Journal of Immunology. 51, 6, p. 1365-1376 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • T-Lymphocytes 100%
  • Population 63%
  • Peptides 34%
  • Cell- and Tissue-Based Therapy 17%
  • Memory 13%

• Cytokine receptor clustering in sensory neurons with an engineered cytokine fusion protein triggers unique pain resolution pathways

  Prado, J., Westerink, R. H. S., Popov-Celeketic, J., Steen-Louws, C., Pandit, A., Versteeg, S., van de Worp, W., Kanters, D. H. A. J., Reedquist, K. A., Koenderman, L., Hack, C. E. & Eijkelkamp, N., 16 Mar 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 11, e2009647118.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Cytokine Receptors 100%
  • Sensory Receptor Cells 88%
  • Interleukin-4 76%
  • Cluster Analysis 74%
  • Cytokines 51%
  12 Citations (Scopus)

  3 Downloads (Pure)

• Differential effects of short- and long-term treatment with mepolizumab on eosinophil kinetics in blood and sputum in eosinophilic asthma

  Hassani, M., Tak, T., van Aalst, C., van Nederveen, S., Tesselaar, K., Vrisekoop, N. & Koenderman, L., 20 Aug 2021, In: iScience. 24, 8, 19 p., 102913.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • mepolizumab 100%
  • Sputum 59%
  • Eosinophils 57%
  • Interleukin-5 47%
  • Asthma 46%
  8 Downloads (Pure)

• Eosinophilic inflammation in COPD: from an inflammatory marker to a treatable trait

  David, B., Bafadhel, M., Koenderman, L. & De Soyza, A., 1 Feb 2021, In: Thorax. 76, 2, p. 188-195 8 p., 215167.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Chronic Obstructive Pulmonary Disease 100%
  • Eosinophils 99%
  • Inflammation 66%
  • Biomarkers 42%
  • Adrenal Cortex Hormones 37%
  17 Downloads (Pure)

• Flow cytometric evaluation of the neutrophil compartment in COVID-19 at hospital presentation: A normal response to an abnormal situation

  Spijkerman, R., Bongers, S. H., Bindels, B. J. J., Tinnevelt, G. H., Giustarini, G., Jorritsma, N. K. N., Buitenwerf, W., van Spengler, D. E. J., Delemarre, E. M., Nierkens, S., van Goor, H. M. R., Jansen, J. J., Vrisekoop, N., Hietbrink, F., Leenen, L. P. H., Kaasjager, K. A. H. & Koenderman, L., Jan 2021, In: Journal of Leukocyte Biology. 109, 1, p. 99-114 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Coronavirus 100%
  • Neutrophils 62%
  • Severe Acute Respiratory Syndrome 8%
  • Neutrophil Activation 8%
  • Point-of-Care Systems 7%
  3 Citations (Scopus)

  5 Downloads (Pure)

• Instant intra-operative neutropenia despite the emergence of banded (CD16dim/CD62Lbright) neutrophils in peripheral blood - An observational study during extensive trauma-surgery in pigs

  Teuben, M., Heeres, M., Blokhuis, T., Hollman, A., Vrisekoop, N., Tan, E., Pfeifer, R., Pape, H-C., Koenderman, L. & Leenen, L. P. H., Mar 2021, In: Injury. 52, 3, p. 426-433 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Neutropenia 100%
  • Swine 78%
  • Neutrophils 78%
  • Observational Studies 77%
  • Wounds and Injuries 48%

• Kinetics of Neutrophil Subsets in Acute, Subacute, and Chronic Inflammation

  Bongers, S. H., Chen, N., van Grinsven, E., van Staveren, S., Hassani, M., Spijkerman, R., Hesselink, L., Lo Tam Loi, A. T., van Aalst, C., Leijte, G. P., Kox, M., Pickkers, P., Hietbrink, F., Leenen, L. P. H., Koenderman, L. & Vrisekoop, N., 24 Jun 2021, In: Frontiers in Immunology. 12, p. 1-12 674079.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Neutrophils 100%
  • Kinetics 92%
  • Inflammation 75%
  • Endotoxemia 34%
  • Bone Marrow 31%
  2 Citations (Scopus)

  5 Downloads (Pure)

• Monitoring eosinophils to guide therapy with Biologics in Asthma: does the compartment matter?

  Koenderman, L., Hassani, M., Mukherjee, M. & Nair, P., Apr 2021, In: Allergy. 76, 4, p. 1294-1297 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Biological Therapy 100%
  • Eosinophils 81%
  • Asthma 65%
  • Endothelium 32%
  • eosinophilopoietin 27%
  7 Downloads (Pure)

• Preoperative Cerebrospinal Fluid Cortisol and the Risk of Postoperative Delirium: A Prospective Study of Older Hip Fracture Patients

  Witlox, J., Adamis, DI., Koenderman, L., Kalisvaart, K., De Jonghe, J. F. M., Houdijk, A. P. J., MacLullich, A. M. J., Eikelenboom, P. & Van Gool, W. A., Apr 2021, In: Dementia and Geriatric Cognitive Disorders. 49, 6, p. 604-610 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Delirium 100%
  • Hip Fractures 94%
  • Hydrocortisone 77%
  • Cerebrospinal Fluid 75%
  • Prospective Studies 55%

• Refractory neutrophils and monocytes in patients with inflammatory bowel disease after repeated bouts of prolonged exercise

  Spijkerman, R., Hesselink, L., Bertinetto, C., Bongers, C. C. W. G., Hietbrink, F., Vrisekoop, N., Leenen, L. P. H., Hopman, M. T. E., Jansen, J. J. & Koenderman, L., Nov 2021, In: Cytometry. Part B, Clinical Cytometry.. 100, 6, p. 676-682 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Inflammatory Bowel Diseases 100%
  • Monocytes 87%
  • Neutrophils 82%
  • Walkers 76%
  • Exercise 68%
  9 Downloads (Pure)

• Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements

  Muller, S. A., Leavis, H. L., Taha, K., Koenderman, L., Chamuleau, S. A. J., Suyker, W. J. L. & Cramer, M. J., 6 Oct 2021, In: JACC Case Rep. 3, 13, p. 1483-1488 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Endocarditis 100%
  • Mitral Valve 96%
  • Interleukin 1 Receptor Antagonist Protein 43%
  • Prednisone 32%
  • Anti-Inflammatory Agents 23%
  10 Downloads (Pure)

• Science and the social media: Time for a reset

  Koenderman, L., Montecucco, F. & Nathoe, H., Aug 2021, In: European Journal of Clinical Investigation. 51, 8, 1 p., e13643.

  Research output: Contribution to journal › Editorial › Academic

• Serum Biomarker Profile Including CCL1, CXCL10, VEGF, and Adenosine Deaminase Activity Distinguishes Active From Remotely Acquired Latent Tuberculosis

  Delemarre, E. M., van Hoorn, L., Bossink, A. W. J., Drylewicz, J., Joosten, S. A., Ottenhoff, T. H. M., Akkerman, O. W., Goletti, D., Petruccioli, E., Navarra, A., van den Broek, B. T. A., Paardekooper, S. P. A., van Haeften, I., Koenderman, L., Lammers, J-W. J., Thijsen, S. F. T., Hofland, R. W. & Nierkens, S., 7 Oct 2021, In: Frontiers in Immunology. 12, p. 1-12 725447.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • C Chemokines 100%
  • Chemokine CXCL10 90%
  • Latent Tuberculosis 83%
  • Adenosine Deaminase 81%
  • Vascular Endothelial Growth Factor A 55%
  1 Downloads (Pure)

• The Systemic Immune Response in COVID-19 Is Associated with a Shift to Formyl-Peptide Unresponsive Eosinophils

  Koenderman, L., Siemers, M. J., van Aalst, C., Bongers, S. H., Spijkerman, R., Bindels, B. J. J., Giustarini, G., van Goor, H. M. R., Kaasjager, K. A. H. & Vrisekoop, N., 5 May 2021, In: Cells. 10, 5, 12 p., 1109.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Cytometry 100%
  • Refractory 99%
  • Eosinophils 92%
  • Flow 61%
  • Peptides 61%

• Thrombotic Events in COVID-19 Are Associated With a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet Reactivity

  22 Apr 2021, In: Frontiers in medicine. 8, p. 1-11 650129.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Coronavirus 100%
  • Blood Platelets 61%
  • Hospitalization 58%
  • thrombin receptor peptide (42-47) 29%
  • Odds Ratio 17%
  2 Citations (Scopus)

  15 Downloads (Pure)
• 2020

  A dominant activating RAC2 variant associated with immunodeficiency and pulmonary disease

  Smits, B. M., Lelieveld, P. H. C., Ververs, F. A., Turkenburg, M., de Koning, C., van Dijk, M., Leavis, H. L., Boelens, J. J., Lindemans, C. A., Bloem, A. C., van de Corput, L., van Montfrans, J., Nierkens, S., van Gijn, M. E., Geerke, D. P., Waterham, H. R., Koenderman, L. & Boes, M., Mar 2020, In: Clinical Immunology. 212, 108248.

  Research output: Contribution to journal › Letter › Academic › peer-review
  12 Citations (Scopus)

• Another look at human granulocyte kinetics

  Hassani, M., 14 Sept 2020, Utrecht University. 240 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Granulocytes 100%
  • Eosinophils 97%
  • Kinetics 72%
  • Neutrophils 56%
  • dupilumab 49%
  10 Downloads (Pure)

• Characterization of the phenotype of human eosinophils and their progenitors in the bone marrow of healthy individuals

  Hassani, M., van Staveren, S., van Grinsven, E., Bartels, M., Tesselaar, K., Leijte, G., Kox, M., Pickkers, P., Vrisekoop, N. & Koenderman, L., 31 Jan 2020, In: Haematologica. 105, 2, p. e52-e56 5 p.

  Research output: Contribution to journal › Letter › Academic › peer-review

  Open Access

  File

• Differentiation and activation of eosinophils in the human bone marrow during experimental human endotoxemia

  Hassani, M., Leijte, G., Bruse, N., Kox, M., Pickkers, P., Vrisekoop, N. & Koenderman, L., Nov 2020, In: Journal of Leukocyte Biology. 108, 5, p. 1665-1671 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Endotoxemia 100%
  • Eosinophils 79%
  • Bone Marrow 60%
  • Granulocyte Precursor Cells 29%
  • Endotoxins 14%
  6 Downloads (Pure)

• Fragile neutrophils in surgical patients: A phenomenon associated with critical illness

  Hesselink, L., Spijkerman, R., Hellebrekers, P., van Bourgondiën, R. J., Blasse, E., Haitjema, S., Huisman, A., van Solinge, W. W., Van Wessem, K. J. P., Koenderman, L., Leenen, L. P. H. & Hietbrink, F., 4 Aug 2020, In: PLoS ONE. 15, 8, 19 p., e0236596.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Critical Illness 100%
  • Neutrophils 84%
  • Leukocytes 76%
  • Propidium 61%
  • Hematology 34%

• Multi-set Pre-processing of Multicolor Flow Cytometry Data

  Folcarelli, R., Tinnevelt, G. H., Hilvering, B., Wouters, K., van Staveren, S., Postma, G. J., Vrisekoop, N., Buydens, L. M. C., Koenderman, L. & Jansen, J. J., 2020, In: Scientific Reports. 10, 1, 12 p., 9716.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Flow Cytometry 100%
  • Cell Count 49%
  • Data Analysis 24%
  • Technology 21%
  5 Downloads (Pure)