Research output per year
Research output per year
Search results
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2025
Lactate controls cancer stemness and plasticity through epigenetic regulation
Nguyen, N. T. B., Gevers, S., Kok, R. N. U., Burgering, L. M., Neikes, H., Akkerman, N., Betjes, M. A., Ludikhuize, M. C., Gulersonmez, C., Stigter, E. C. A., Vercoulen, Y., Drost, J., Clevers, H., Vermeulen, M., van Zon, J. S., Tans, S. J., Burgering, B. M. T. & Rodríguez Colman, M. J., 1 Apr 2025, In: Cell Metabolism. 37, 4, p. 903-919.e10Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
NAC regulates metabolism and cell fate in intestinal stem cells
Ramalho, S., Alkan, F., Prekovic, S., Jastrzebski, K., Barberà, E. P., Hoekman, L., Altelaar, M., de Heus, C., Liv, N., Rodríguez-Colman, M. J., Yilmaz, M., van der Kammen, R., Fedry, J., de Gooijer, M. C., Suijkerbuijk, S. J. E., Faller, W. J. & Silva, J., 10 Jan 2025, In: Science advances. 11, 2, p. eadn9750 eadn9750.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
2023
Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis
Hendriks, D., Brouwers, J. F., Hamer, K., Geurts, M. H., Luciana, L., Massalini, S., López-Iglesias, C., Peters, P. J., Rodríguez-Colman, M. J., Chuva de Sousa Lopes, S., Artegiani, B. & Clevers, H., Nov 2023, In: Nature Biotechnology. 41, 11, p. 1567-1581 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Downloads (Pure) -
2022
Rewiring glucose metabolism improves 5-FU efficacy in p53-deficient/KRAS G12D glycolytic colorectal tumors
Ludikhuize, M. C., Gevers, S., Nguyen, N. T. B., Meerlo, M., Roudbari, S. K. S., Gulersonmez, M. C., Stigter, E. C. A., Drost, J., Clevers, H., Burgering, B. M. T. & Rodríguez Colman, M. J., Dec 2022, In: Communications biology. 5, 1, 1 p., 1159.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Downloads (Pure) -
2021
A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
Hornsveld, M., Feringa, F. M., Krenning, L., van den Berg, J., Smits, L. M. M., Nguyen, N. B. T., Rodríguez-Colman, M. J., Dansen, T. B., Medema, R. H. & Burgering, B. M. T., 26 Jan 2021, In: Cell Reports. 34, 4, 108675.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)3 Downloads (Pure) -
Protocol to profile the bioenergetics of organoids using Seahorse
Ludikhuize, M. C., Meerlo, M., Burgering, B. M. T. & Rodríguez Colman, M. J., 19 Mar 2021, In: STAR protocols. 2, 1, 1 p., 100386.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)4 Downloads (Pure)