Central Diagnostic Laboratory

Research output

Research output per year 1987 2006 2016 2017 2018 2019 2020 2021 2022 2023 2024 2024

• 512 Article
• 60 Review article
• 44 Doctoral thesis 1 (Research UU / Graduation UU)
• 33 Comment/Letter to the editor
• 74 More
  • 25 Meeting Abstract
  • 13 Editorial
  • 10 Chapter
  • 10 Preprint
  • 9 Letter
  • 2 Short survey
  • 1 Book
  • 1 Conference contribution
  • 1 Foreword/postscript
  • 1 Literature review
  • 1 Patent

Research output per year

Research output per year

Search results

• 2024

  Improving our understanding on the clinical role of plasmin-mediated von Willebrand factor degradation

  Otmani, H. E., Vanhoorelbeke, K. & Tersteeg, C., 1 Sept 2024, In: Current Opinion in Hematology. 31, 5, p. 245-250 6 p.

  Research output: Contribution to journal › Review article › peer-review

• mRNA delivery systems for cancer immunotherapy: Lipid nanoparticles and beyond

  Estapé Senti, M., García Del Valle, L. & Schiffelers, R. M., Mar 2024, In: Advanced Drug Delivery Reviews. 206, p. 1-17 17 p., 115190.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Nanoparticles 100%
  • Immunotherapy 99%
  • Lipid 77%
  • Lipids 73%
  • Messenger RNA 64%
  35 Downloads (Pure)

• The Effects of FABP4 on Cardiovascular Disease in the Aging Population

  van der Ark-Vonk, E. M., Puijk, M. V., Pasterkamp, G. & van der Laan, S. W., May 2024, In: Current atherosclerosis reports. 26, 5, p. 163-175 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
• 2023

  Circular RNAs in Cardiovascular Diseases: Regulation and Therapeutic Applications

  Wang, L., Xu, G. E., Spanos, M., Li, G., Lei, Z., Sluijter, J. P. G. & Xiao, J., Jan 2023, In: Research. 6, 19 p., 0038.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Circular RNAs 100%
  • Cardiovascular Diseases 53%
  • Therapeutics 11%
  • Untranslated RNA 11%
  • Technology 6%
  7 Downloads (Pure)

• Factor XII Explored with AlphaFold - Opportunities for Selective Drug Development

  Frunt, R., El Otmani, H., Gibril Kaira, B., de Maat, S. & Maas, C., 7 Feb 2023, In: Thrombosis and Haemostasis. 123, 2, p. 177-185 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Factor XII 100%
  • Drug Development 66%
  • Thrombosis 27%
  • Equipment and Supplies 15%
  • Kringles 13%

• Levodopa-loaded nanoparticles for the treatment of Parkinson's disease

  van Vliet, E. F., Knol, M. J., Schiffelers, R. M., Caiazzo, M. & Fens, M. H. A. M., Aug 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 360, p. 212-224 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Levodopa 100%
  • Dopamine 84%
  • Nanoparticles 79%
  • Parkinson Disease 75%
  • Nanoparticle 44%
  8 Downloads (Pure)

• Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

  Davidson, S. M., Boulanger, C. M., Aikawa, E., Badimon, L., Barile, L., Binder, C. J., Brisson, A., Buzas, E., Emanueli, C., Jansen, F., Katsur, M., Lacroix, R., Lim, S. K., Mackman, N., Mayr, M., Menasché, P., Nieuwland, R., Sahoo, S., Takov, K., Thum, T., & 4 othersVader, P., Wauben, M. H. M., Witwer, K. & Sluijter, J. P. G., 1 Jan 2023, In: Cardiovascular research. 119, 1, p. 45-63 19 p.

  Research output: Contribution to journal › Review article › peer-review

  • Extracellular Vesicles 100%
  • Exosomes 99%
  • Heart Failure 17%
  • RNA 16%
  • Lipids 15%

• Nanomedicines: An approach to treat placental insufficiency and the current challenges

  van Kammen, C. M., van Woudenberg, S. J., Schiffelers, R., Terstappen, F. & Lely, A. T., Aug 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 360, p. 57-68 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Placental Insufficiency 100%
  • Nanomedicine 88%
  • Nanoparticles 27%
  • Safety 26%
  • Maternal Health 26%
  15 Downloads (Pure)

• Risk Factors for Immune Checkpoint Inhibitor-Mediated Cardiovascular Toxicities

  Yousif, L. I., Screever, E. M., Versluis, D., Aboumsallem, J. P., Nierkens, S., Manintveld, O. C., de Boer, R. A. & Meijers, W. C., Jul 2023, In: Current Oncology Reports. 25, 7, p. 753-763 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Myocarditis 100%
  • Neoplasms 57%
  • Pericarditis 55%
  • Preexisting Condition Coverage 53%
  • Vasculitis 45%

• Sex differences in the genetic and molecular mechanisms of coronary artery disease

  Sakkers, T. R., Mokry, M., Civelek, M., Erdmann, J., Pasterkamp, G., Diez Benavente, E. & den Ruijter, H. M., Nov 2023, In: Atherosclerosis. 384, 117279.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Sex Characteristics 100%
  • Coronary Artery Disease 88%
  • Molecular Biology 86%
  • Smooth Muscle Myocytes 31%
  • Atherosclerosis 28%
  13 Downloads (Pure)
• 2022

  Extracellular Vesicle-Based Hybrid Systems for Advanced Drug Delivery

  Rodríguez, D. A. & Vader, P., Feb 2022, In: Pharmaceutics. 14, 2, 267.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Extracellular Vesicles 100%
  • Drug Delivery Systems 83%
  • Synthetic Drugs 77%
  • Drug 44%
  • Nanomedicine 36%
  2 Citations (Scopus)

  7 Downloads (Pure)

• The Applications of Single-Cell RNA Sequencing in Atherosclerotic Disease

  Slenders, L., Tessels, D. E., van der Laan, S. W., Pasterkamp, G. & Mokry, M., 8 Feb 2022, In: Frontiers in cardiovascular medicine. 9, p. 1-12 826103.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • RNA Sequence Analysis 100%
  • Atherosclerotic Plaques 93%
  • Atherosclerosis 72%
  • Phenotype 53%
  • Rupture 37%
  16 Downloads (Pure)
• 2021

  A call for the standardised reporting of factors affecting the exogenous loading of extracellular vesicles with therapeutic cargos

  Rankin-Turner, S., Vader, P., O'Driscoll, L., Giebel, B., Heaney, L. M. & Davies, O. G., Jun 2021, In: Advanced Drug Delivery Reviews. 173, p. 479-491 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Extracellular Vesicles 100%
  • Drug 44%
  • Nanoparticle 42%
  • Nanoparticles 30%
  • Benchmarking 18%
  8 Downloads (Pure)

• Approaches to surface engineering of extracellular vesicles

  Richter, M., Vader, P. & Fuhrmann, G., Jun 2021, In: Advanced Drug Delivery Reviews. 173, p. 416-426 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Extracellular Vesicles 100%
  • Mammalian Cell 29%
  • Surface 26%
  • Communication 25%
  • Metabolic 22%

• Blood Clotting and the Pathogenesis of Types I and II Hereditary Angioedema

  de Maat, S., Joseph, K., Maas, C. & Kaplan, A. P., Jun 2021, In: Clinical Reviews in Allergy & Immunology. 60, 3, p. 348-356 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Hereditary Angioedema Types I and II 100%
  • Prekallikrein 87%
  • Blood Coagulation 65%
  • Hereditary Angioedemas 54%
  • Factor XII 54%
  18 Downloads (Pure)

• Evaluation of non-invasive imaging parameters in coronary microvascular disease: a systematic review

  Groepenhoff, F., Klaassen, R. G. M., Valstar, G. B., Bots, S. H., Onland-Moret, N. C., Den Ruijter, H. M., Leiner, T. & Eikendal, A. L. M., Dec 2021, In: BMC medical imaging. 21, 1, p. 1-23 5.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Coronary Disease 100%
  • Angina Pectoris 85%
  • Systematic Reviews 83%
  • Positron-Emission Tomography 70%
  • Echocardiography 63%
  3 Downloads (Pure)

• Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design

  Kooijmans, S. A. A., de Jong, O. G. & Schiffelers, R. M., Jun 2021, In: Advanced Drug Delivery Reviews. 173, p. 252-278 27 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Extracellular Vesicles 100%
  • Drug Delivery Systems 83%
  • Drug 44%
  • Effector 30%
  • Molecule 29%
  26 Downloads (Pure)

• Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies

  Escudé Martinez de Castilla, P., Tong, L., Huang, C., Sofias, A. M., Pastorin, G., Chen, X., Storm, G., Schiffelers, R. M. & Wang, J-W., Aug 2021, In: Advanced Drug Delivery Reviews. 175, p. 1-39 113801.

  Research output: Contribution to journal › Review article › peer-review

  • Extracellular Vesicles 100%
  • Drug Delivery Systems 83%
  • Systematic Reviews 62%
  • Pharmaceutical 62%
  • Drug 44%

• Illuminating RNA trafficking and functional delivery by extracellular vesicles

  de Voogt, W. S., Tanenbaum, M. E. & Vader, P., Jul 2021, In: Advanced Drug Delivery Reviews. 174, p. 250-264 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Transfer RNA 100%
  • Extracellular Vesicles 88%
  • RNA 52%
  • Safety 32%
  • Molecule 12%
  6 Downloads (Pure)

• Polymeric delivery systems for nucleic acid therapeutics: Approaching the clinic

  van den Berg, A. I. S., Yun, C-O., Schiffelers, R. M. & Hennink, W. E., 10 Mar 2021, In: Journal of controlled release : official journal of the Controlled Release Society. 331, p. 121-141 21 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Nucleic Acids 100%
  • Nucleic Acid 85%
  • Polymers 30%
  • Therapeutics 16%
  • Genetic Therapy 15%
  16 Downloads (Pure)

• Roadmap Consensus on Carotid Artery Plaque Imaging and Impact on Therapy Strategies and Guidelines: An International, Multispecialty, Expert Review and Position Statement

  Saba, L., Brinjikji, W., Spence, J. D., Wintermark, M., Castillo, M., de Borst, G. J. D., Yang, Q., Yuan, C., Buckler, A., Edjlali, M., Saam, T., Saloner, D., Lal, B. K., Capodanno, D., Sun, J., Balu, N., Naylor, R., Lugt, A. V. D., Wasserman, B. A., Kooi, M. E., & 13 othersWardlaw, J., Gillard, J., Lanzino, G., Hedin, U., Mikulis, D., Gupta, A., DeMarco, J. K., Hess, C., Goethem, J. . V., Hatsukami, T., Rothwell, P., Brown, M. M. & Moody, A. R., Sept 2021, In: American Journal of Neuroradiology. 42, 9, p. 1566-1575

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Carotid Stenosis 100%
  • Pathologic Constriction 70%
  • Guidelines 56%
  • Carotid Artery Diseases 53%
  • Clinical Decision-Making 23%
  6 Downloads (Pure)

• Targeting of promising transmembrane proteins for diagnosis and treatment of pancreatic ductal adenocarcinoma

  Mashayekhi, V., Mocellin, O., Fens, M. H. A. M., Krijger, G. C., Brosens, L. A. A. & Oliveira, S., 2021, In: Theranostics. 11, 18, p. 9022-9037 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Adenocarcinoma 100%
  • Proteins 46%
  • Therapeutics 20%
  • Cytotoxins 20%
  • gemcitabine 20%
  4 Downloads (Pure)

• The changing landscape of the vulnerable plaque: a call for fine-tuning of preclinical models

  Buono, M. F., Slenders, L., Wesseling, M., Hartman, R. J. G., Monaco, C., den Ruijter, H. M., Pasterkamp, G. & Mokry, M., Dec 2021, In: Vascular Pharmacology. 141, p. 1-10 106924.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Cell Plasticity 100%
  • Rupture 63%
  • Thrombosis 57%
  • Myocardial Infarction 54%
  • Stroke 51%
  10 Downloads (Pure)

• The interplay between drivers of erythropoiesis and iron homeostasis in rare hereditary anemias: Tipping the balance

  Grootendorst, S., de Wilde, J., van Dooijeweert, B., van Vuren, A., van Solinge, W., Schutgens, R., van Wijk, R. & Bartels, M., 2 Feb 2021, In: International journal of molecular sciences. 22, 4, 17 p., 2204.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • anemias 100%
  • homeostasis 90%
  • Erythropoiesis 71%
  • Iron 55%
  • Anemia 51%
  6 Downloads (Pure)

• Therapeutic SERPINs: Improving on Nature

  Maas, C. & de Maat, S., 31 Mar 2021, In: Frontiers in cardiovascular medicine. 8, p. 1-8 648349.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Serine Proteinase Inhibitors 100%
  • Peptide Hydrolases 13%
  • Therapeutics 12%
  • Social Responsibility 6%
  • Serine Proteases 5%
  1 Downloads (Pure)

• The transverse aortic constriction heart failure animal model: a systematic review and meta-analysis

  Bosch, L., de Haan, J. J., Bastemeijer, M., van der Burg, J., van der Worp, E., Wesseling, M., Viola, M., Odille, C., el Azzouzi, H., Pasterkamp, G., Sluijter, J. P. G., Wever, K. E. & de Jager, S. C. A., Nov 2021, In: Heart Failure Reviews. 26, 6, p. 1515-1524 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Constriction 100%
  • Meta-Analysis 77%
  • Systematic Reviews 76%
  • Heart Failure 75%
  • Animal Models 74%
  8 Downloads (Pure)
• 2020

  Cellular and molecular mechanism of cardiac regeneration: A comparison of newts, zebrafish, and mammals

  de Wit, L., Fang, J., Neef, K., Xiao, J., Doevendans, P. A., Schiffelers, R. M., Lei, Z. & Sluijter, J. P. G., Sept 2020, In: Biomolecules. 10, 9, p. 1-20 20 p., 1204.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Salamandridae 100%
  • Zebrafish 68%
  • Cardiac Myocytes 62%
  • Mammals 59%
  • Regeneration 56%
  7 Citations (Scopus)

  3 Downloads (Pure)

• Delivering the power of nanomedicine to patients today

  Germain, M., Caputo, F., Metcalfe, S., Tosi, G., Spring, K., Åslund, A. K. O., Pottier, A., Schiffelers, R., Ceccaldi, A. & Schmid, R., 10 Oct 2020, In: Journal of controlled release : official journal of the Controlled Release Society. 326, p. 164-171 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Nanomedicine 100%
  • Technology 25%
  • Smart Materials 9%
  • Optics and Photonics 8%
  • Big Data 7%
  4 Downloads (Pure)

• Extracellular Vesicle-Associated Proteins in Tissue Repair

  Roefs, M. T., Sluijter, J. P. G. & Vader, P., Dec 2020, In: Trends in Cell Biology. 30, 12, p. 990-1013 24 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Extracellular Vesicles 100%
  • Proteins 31%
  • Wound Healing 9%
  • Stem Cells 7%
  • Direction compound 7%

• Extracellular vesicles as drug delivery systems: Why and how?

  Elsharkasy, O. M., Nordin, J. Z., Hagey, D. W., de Jong, O. G., Schiffelers, R. M., Andaloussi, S. EL. & Vader, P., 2020, In: Advanced Drug Delivery Reviews. 159, p. 332-343 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Extracellular Vesicles 100%
  • Drug Delivery Systems 83%
  • Drug 44%
  • Synthetic Drugs 23%
  • Drug Carrier 22%
  7 Downloads (Pure)

• Growth differentiation factor 15 in adverse cardiac remodelling: from biomarker to causal player

  Wesseling, M., de Poel, J. H. C. & de Jager, S. C. A., 1 Aug 2020, In: ESC heart failure. 7, 4, p. 1488-1501 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Growth Differentiation Factor 15 100%
  • Biomarkers 42%
  • Heart Failure 26%
  • Pathology 9%
  • Transforming Growth Factors 7%

• Nanocarrier-based drug combination therapy for glioblastoma

  Zhao, M., van Straten, D., Broekman, M. L. D., Preat, V. & Schiffelers, R. M., 1 Jan 2020, In: Theranostics. 10, 3, p. 1355-1372 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Combination Drug Therapy 100%
  • Glioblastoma 97%
  • Nanomedicine 63%
  • Drug Combinations 25%
  • Blood-Brain Barrier 23%

• Repairing the heart: State-of the art delivery strategies for biological therapeutics

  Yang, Q., Fang, J., Lei, Z., Sluijter, J. P. G. & Schiffelers, R., May 2020, In: Advanced Drug Delivery Reviews. 160, p. 1-18 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Heart 100%
  • Protein 63%
  • Angiogenic 56%
  • Myocardium 51%
  • Angiogenic Proteins 46%

• Sex-Specific Aspects in the Pathophysiology and Imaging of Coronary Macro- and Microvascular Disease

  Groepenhoff, F., Bots, S. H., Kessler, E. L., Sickinghe, A. A., Eikendal, A. L. M., Leiner, T. & den Ruijter, H. M., Feb 2020, In: Journal of Cardiovascular Translational Research. 13, 1, p. 39-46 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Sex Characteristics 100%
  • Coronary Artery Disease 59%
  • Perfusion Imaging 42%

• The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy

  Francia, V., Schiffelers, R. M., Cullis, P. R. & Witzigmann, D., Sept 2020, In: Bioconjugate Chemistry. 31, 9, p. 2046-2059 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Gene therapy 100%
  • Lipids 76%
  • Nanoparticles 56%
  • Genetic Therapy 52%
  • Lipid 39%
• 2019

  3D Bioprinting: from Benches to Translational Applications

  Heinrich, M. A., Liu, W., Jimenez, A., Yang, J., Akpek, A., Liu, X., Pi, Q., Mu, X., Hu, N., Schiffelers, R. M., Prakash, J., Xie, J. & Zhang, Y. S., 7 Jun 2019, In: Small. 15, 23, 1805510.

  Research output: Contribution to journal › Review article › peer-review

  • Bioprinting 100%
  • Tissue 55%
  • Instrumentation 31%
  • Biomimetics 27%
  • Shape 21%

• Adverse Drug Reactions to Guideline-Recommended Heart Failure Drugs in Women: A Systematic Review of the Literature

  Bots, S. H., Groepenhoff, F., Eikendal, A. L. M., Tannenbaum, C., Rochon, P. A., Regitz-Zagrosek, V., Miller, V. M., Day, D., Asselbergs, F. W. & den Ruijter, H. M., Mar 2019, In: JACC. Heart failure. 7, 3, p. 258-266 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Drug-Related Side Effects and Adverse Reactions 100%
  • Systematic Reviews 79%
  • Guidelines 69%
  • Ivabradine 27%
  • Heart Failure 26%

• Bacterial membrane vesicles as promising vaccine candidates

  Jiang, L., Schinkel, M., van Essen, M. & Schiffelers, R. M., Dec 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 145, p. 1-6 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Vaccines 100%
  • Lipid 91%
  • Adjuvant 82%
  • Membranes 79%
  • Pipeline 77%

• Drug Delivery with Extracellular Vesicles: From Imagination to Innovation

  De Jong, O. G., Kooijmans, S. A. A., Murphy, D. E., Jiang, L., Evers, M. J. W., Sluijter, J. P. G., Vader, P. & Schiffelers, R. M., Jul 2019, In: Accounts of Chemical Research. 52, 7, p. 1761-1770 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • MicroRNA 100%
  • Drug 85%
  • Heterogeneity 75%
  • Nucleic Acid 68%
  • Protein 67%
  7 Downloads (Pure)

• Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking

  Murphy, D. E., de Jong, O. G., Brouwer, M., Wood, M. J., Lavieu, G., Schiffelers, R. M. & Vader, P., 15 Mar 2019, In: Experimental & molecular medicine. 51, 3, 32.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Extracellular Vesicles 100%
  • Effector 92%
  • Pharmacokinetics 63%
  • Modification 47%
  • Drug 44%

• Reassessing the Mechanisms of Acute Coronary Syndromes: The "vulnerable plaque" and superficial erosion

  Libby, P., Pasterkamp, G., Crea, F. & Jang, I. K., 4 Jan 2019, In: Circulation Research. 124, 1, p. 150-160 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Acute Coronary Syndrome 100%
  • Rupture 84%
  • Thrombosis 38%
  • Extracellular Traps 23%
  • Macrophages 23%
  18 Citations (Scopus)

• Red Blood Cells: Chasing Interactions

  Pretini, V., Koenen, M. H., Kaestner, L., Fens, M. H. A. M., Schiffelers, R. M., Bartels, M. & Van Wijk, R., 31 Jul 2019, In: Frontiers in Physiology. 10, JUL, 945.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Cell Communication 100%
  • Erythrocytes 83%
  • Cellular Structures 16%
  • Carbon Dioxide 15%
  • Cell Body 15%

• SERPINs-From Trap to Treatment

  Sanrattana, W., Maas, C. & de Maat, S., 2019, In: Frontiers in medicine. 6, FEB, 8 p., 25.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Serine Proteinase Inhibitors 100%
  • Serine Proteases 29%
  • Kallikrein-Kinin System 19%
  • Hereditary Angioedemas 18%
  • Enzymes 14%
  1 Downloads (Pure)

• The EPO-FGF23 Signaling Pathway in Erythroid Progenitor Cells: Opening a New Area of Research

  Van Vuren, A. J., Gaillard, C. A. J. M., Eisenga, M. F., Van Wijk, R. & Van Beers, E. J., 26 Mar 2019, In: Frontiers in Physiology. 10, MAR, 304.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • fibroblast growth factor 23 100%
  • Erythroid Precursor Cells 91%
  • Erythropoietin 52%
  • Erythropoiesis 19%
  • Bone Marrow 16%
• 2018

  Nanomedicines for the treatment of hematological malignancies

  Deshantri, A. K., Varela Moreira, A., Ecker, V., Mandhane, S. N., Schiffelers, R. M., Buchner, M. & Fens, M. H. A. M., 10 Oct 2018, In: Journal of Controlled Release. 287, p. 194-215 22 p.

  Research output: Contribution to journal › Review article › peer-review

  • Haematological 100%
  • Nanomedicine 89%
  • Hematologic Neoplasms 71%
  • Nanoparticles 26%
  • Antineoplastic Agent 20%

• Squeezing for life - Properties of red blood cell deformability

  Huisjes, R., Bogdanova, A., van Solinge, W. W., Schiffelers, R. M., Kaestner, L. & van Wijk, R., 1 Jun 2018, In: Frontiers in Physiology. 9, JUN, 22 p., 656.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Congenital Hemolytic Anemia 100%
  • Hereditary Xerocytosis 59%
  • Erythrocytes 48%
  • Hereditary Spherocytosis 46%
  • Thalassemia 37%

• State-of-the-Art Design and Rapid-Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery

  Evers, M. J. W., Kulkarni, J. A., van der Meel, R., Cullis, P. R., Vader, P. & Schiffelers, R. M., 11 Sept 2018, In: SMALL METHODS. 2, 9, 1700375.

  Research output: Contribution to journal › Review article › peer-review

  • Nucleic acids 100%
  • Small Interfering RNA 94%
  • Lipids 91%
  • RNA 82%
  • Nanoparticles 67%

• The Lupus Anticoagulant Paradox

  Molhoek, J. E., de Groot, P. G. & Urbanus, R. T., Jul 2018, In: Seminars in Thrombosis and Hemostasis. 44, 5, p. 445-452 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lupus Coagulation Inhibitor 100%
  • Thrombosis 58%
  • Antiphospholipid Antibodies 47%
  • Antiphospholipid Syndrome 45%
  • Antibodies 42%

• The morphological and molecular mechanisms of epithelial/endothelial-to-mesenchymal transition and its involvement in atherosclerosis

  Wesseling, M., Sakkers, T. R., de Jager, S. C. A., Pasterkamp, G. & Goumans, M. J., Jul 2018, In: Vascular Pharmacology. 106, p. 1-8 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epithelial-Mesenchymal Transition 100%
  • Atherosclerosis 77%
  • Cell Transdifferentiation 36%
  • Cell Shape 28%
  • Atherosclerotic Plaques 25%
• 2017

  Cardiorenal disease connection during post-menopause: The protective role of estrogen in uremic toxins induced microvascular dysfunction

  Pei, J., Harakalova, M., den Ruijter, H., Pasterkamp, G., Duncker, D. J., Verhaar, M. C., Asselbergs, F. W. & Cheng, C., 1 Jul 2017, In: International Journal of Cardiology. 238, p. 22-30 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Postmenopause 100%
  • Chronic Renal Insufficiency 67%
  • Indican 67%
  • Estrogens 60%
  • Phosphates 38%
  1 Citation (Scopus)