Center for Translational Immunology (CTI) Research

Research output

Research output per year 1989 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2024

• 1046 Article
• 136 Review article
• 92 Meeting Abstract
• 80 Comment/Letter to the editor
• 177 More
  • 75 Doctoral thesis 1 (Research UU / Graduation UU)
  • 42 Letter
  • 18 Chapter
  • 17 Editorial
  • 5 Short survey
  • 5 Doctoral thesis 2 (Research NOT UU / Graduation UU)
  • 4 Literature review
  • 3 Preprint
  • 2 Inaugural speech
  • 2 Abstract
  • 2 Poster
  • 1 Book editing
  • 1 Special issue

Research output per year

Research output per year

Search results

• 2024

  Back to nature: Lymphocyte dynamics in a more natural mouse model

  de Dios Panal, E., 3 Jun 2024, Utrecht: Utrecht University. 223 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Lymphocytes 100%
  • T-Lymphocytes 89%
  • Maraviroc 39%
  • Deoxyuridine 16%
  • Immune Reconstitution 16%

• Engineering the next-generation of T cell-based cancer immunotherapies

  Hernández-López, P., 13 Feb 2024, Utrecht: Utrecht University. 270 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Haematological 100%
  • Purity 35%
  2 Downloads (Pure)

• Exploring Molecular Mechanisms and Biomarkers in Psoriasis: Insights from Omics Technologies and Single-Cell Analyses

  Deng, J., 25 Jan 2024, Utrecht University. 228 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  • Single-Cell Analysis 100%
  • Psoriasis 73%
  • Technology 48%
  • Biomarkers 48%
  • Skin 37%

• From Evasion to Elimination: Enhancing IgA therapy through myeloid checkpoint inhibition

  Chan, C., 11 Sept 2024, Utrecht: Utrecht University. 290 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

• Grow old or die young: Lymphocyte dynamics in humans

  Bruckmaier, C., 3 Jun 2024, Utrecht University. 166 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Lymphocytes 100%
  • T-Cell Antigen Receptor 88%
  • Longevity 77%
  • T-Lymphocytes 71%
  • Natural Killer Cells 53%
  1 Downloads (Pure)

• Human islet amyloid polypeptide (IAPP): a culprit of Type 2 Diabetes Mellitus (T2DM) and T2DM neuropathy

  Albariqi, M., 16 May 2024, Utrecht University. 248 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  • Islet Amyloid Polypeptide 100%
  • Diabetic Neuropathies 58%
  • Type 2 Diabetes Mellitus 53%
  • Peripheral Nervous System Diseases 52%
  • 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole 32%

• Preclinical models and IgA anti-GD2 antibody therapy for neuroblastoma

  Stip, M., 12 Jun 2024, Utrecht University. 253 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Neuroblastoma 100%
  • Immunoglobulin A 93%
  • Anti-Idiotypic Antibodies 84%
  • Antibodies 55%
  • Neutrophils 43%

• T cell based immunotherapies in oncology; new approaches and improved strategies

  Meringa, A., 6 Jun 2024, Utrecht: Utrecht University. 227 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Immunotherapy 100%
  • T-Lymphocytes 70%
  • Neoplasms 36%
  • Cell- and Tissue-Based Therapy 35%
  • HLA-A*24:02 antigen 34%

• The old and the new: immune inhibitory receptors for the treatment of cancer

  Singh, A., 9 Jan 2024, Utrecht: Utrecht University. 264 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  • Immunotherapy 100%
  • Neoplasms 73%
  • Therapeutics 37%
  • Collagen 28%

• Towards global prevention of severe pediatric RSV infection

  Löwensteyn, Y., 5 Sept 2024, Utrecht: Utrecht University. 206 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

• Vγ9Vδ2TCR and Beyond: Novel Insights and Strategies for Advanced T cell-based Immunotherapies

  Cleven, A., 24 Apr 2024, Utrecht University. 188 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Immunotherapy 100%
  • T-Lymphocytes 70%
  • Neoplasms 36%
  • Adoptive Immunotherapy 24%
  • T-Lymphocyte Subsets 20%
  13 Downloads (Pure)
• 2023

  Food allergy management in daily life: accidental allergic reactions, cofactors and adherence to dietary advice

  Versluis, A., 10 Jan 2023, Utrecht: Utrecht University. 193 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Food Hypersensitivity 100%
  • Hypersensitivity 69%
  • Food 59%
  • Respiratory System 22%
  • Allergens 22%
  51 Downloads (Pure)

• Hit the brakes! Inhibitory immune receptors as therapeutic target for neutrophil-driven pathologies

  Geerdink, R., 28 Jun 2023, Utrecht: Utrecht University. 160 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Neutrophils 100%
  • Pathology 80%
  • leukocyte-associated immunoglobulin-like receptor 1 62%
  • Extracellular Traps 22%
  • Chronic Granulomatous Disease 21%
  15 Downloads (Pure)

• Immune inhibitory receptors in blood and barrier tissues: conveyers of context

  von Richthofen, H., 28 Jun 2023, Utrecht University. 220 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Leukocytes 100%
  • staphylococcal delta toxin 37%
  • S100 Proteins 37%
  • Pattern Recognition Receptors 26%
  • CAP18 lipopolysaccharide-binding protein 15%
  12 Downloads (Pure)

• Immunotherapy with T cells: New strategies and improved designs

  van Diest, E., 13 Apr 2023, Utrecht: Utrecht University. 193 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Immunotherapy 100%
  • T-Lymphocytes 70%
  • Neoplasms 36%
  • Cell- and Tissue-Based Therapy 30%
  • Therapeutics 18%
  25 Downloads (Pure)

• Mastering the game of hide and seek: Enhancing the Immunogenicity of Neuroblastoma

  Cornel, A., 16 Feb 2023, Utrecht: Utrecht University. 317 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Neuroblastoma 100%
  • T-Lymphocytes 38%
  • Immunologic Memory 34%
  • Immunologic Monitoring 32%
  • Cell Lineage 26%
  2 Downloads (Pure)

• Respiratory viruses in infancy and rapid RSV diagnostics

  Zuurbier, R., 1 Jun 2023, Utrecht University. 203 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Respiratory Syncytial Viruses 100%
  • Viruses 56%
  • Hospitalization 17%
  • Rhinovirus 15%
  • Point-of-Care Systems 13%
  19 Downloads (Pure)

• Towards new guidelines for diagnosis and treatment of primary antibody deficiency: Using translational studies to uncover new diagnostic and therapeutic modalities

  Smits, B., 15 Nov 2023, Utrecht University. 336 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Primary Immunodeficiency Diseases 100%
  • Guidelines 47%
  • Interstitial Lung Diseases 33%
  • Common Variable Immunodeficiency 25%
  • T-Lymphocytes 22%
  27 Downloads (Pure)

• We are all on the same team: Growing together towards RSV prevention

  Langedijk, A., 27 Oct 2023, Utrecht University. 304 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • industry 100%
  • public service 42%
  • transparency 41%
  • public sector 40%
  • public health 35%
  15 Downloads (Pure)
• 2022

  A Poorest-First Approach to RSV Vaccine Development

  Mazur, N., 12 Sept 2022, Utrecht University. 225 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Respiratory Syncytial Virus Vaccines 100%
  • Ethical Analysis 33%
  • Translational Medical Research 24%
  • Age Distribution 23%
  • Ethics 21%
  35 Downloads (Pure)

• ARCOBALENO cell therapy to treat pediatric cancer patients

  Lo Presti, V., 21 Apr 2022, Utrecht University. 245 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cell- and Tissue-Based Therapy 100%
  • Pediatrics 67%
  • Chimeric Antigen Receptors 47%
  • Neoplasms 34%
  • T-Lymphocytes 21%
  7 Downloads (Pure)

• A systems approach to unraveling progenitor potential and disease-associated immune cell networks.

  Deva Prasad, A. D., 29 Jun 2022, Utrecht University. 204 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • hematopoiesis 100%
  • hematopoietic stem cells 72%
  • cells 57%
  • branching 48%
  • pandemic 33%
  7 Downloads (Pure)

• Diagnosis and treatment of Mevalonate Kinase Deficiency

  Jeyaratnam, J., 8 Sept 2022, Utrecht University. 128 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Mevalonate Kinase Deficiency 100%
  • canakinumab 74%
  • Stem Cell Transplantation 46%
  • Genetic Testing 30%
  • Mevalonic Acid 19%
  7 Downloads (Pure)

• Emerging insights into early atherosclerosis in adolescents with chronic disease

  Ververs, F., 6 Dec 2022, Utrecht University. 214 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Natural Killer T-Cells 100%
  • Atherosclerosis 67%
  • Chronic Disease 61%
  • Aorta 20%
  • CD1d Antigen 19%
  13 Downloads (Pure)

• From mouse to human: Metabolic targeting of cancer with TEG-based immunotherapy

  Johanna-Gomes, I., 9 Feb 2022, Utrecht University. 164 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Immunotherapy 100%
  • T-Lymphocytes 70%
  • Neoplasms 36%
  • Safety 18%
  • Adoptive Transfer 18%
  13 Downloads (Pure)

• Immune inhibitory receptors in host–microbe interaction

  Rumpret, M., 17 Mar 2022, Utrecht University. 188 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  • Leukocytes 100%
  • S100 Proteins 99%
  • Peptides 40%
  • staphylococcal delta toxin 37%
  • CAP18 lipopolysaccharide-binding protein 30%

• Improving allergenicity risk assessment of novel foods

  Smits, M., 19 Jan 2022, Utrecht: Utrecht University. 205 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Risk Assessment 100%
  • Food 84%
  • Proteins 44%
  • Food Hypersensitivity 12%
  • Proteolysis 10%
  12 Downloads (Pure)

• Let's be adaptable: Tissue T cell adaptation in homeostasis and inflammation

  Lutter, L., 29 Nov 2022, Utrecht: Utrecht University. 228 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • T-lymphocytes 100%
  • inflammation 99%
  • homeostasis 94%
  • laminae (animals) 49%
  • tissues 48%
  27 Downloads (Pure)

• Maintenance of the virus-specific CD8+ T-cell repertoire: Implications for vaccine strategies

  Lanfermeijer, J., 15 Sept 2022, Utrecht: Utrecht University. 284 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Vaccines 100%
  • Maintenance 93%
  • Viruses 88%
  • T-Lymphocytes 82%
  • Vaccination 29%

• New insights into the regulation of inflammation and fibrosis in systemic sclerosis

  Ferreira Carvalheiro, T., 22 Feb 2022, Utrecht University. 315 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Systemic Scleroderma 100%
  • Fibrosis 65%
  • Inflammation 51%
  • leukocyte-associated immunoglobulin-like receptor 1 14%
  • Fibroblasts 10%
  7 Downloads (Pure)

• Osteoarthritis: Towards a progressive APPROACH

  van Helvoort, E., 15 Mar 2022, Utrecht University. 279 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Osteoarthritis 100%
  • Neuralgia 46%
  • Interleukin-4 41%
  • Joints 39%
  • Phenotype 33%
  7 Downloads (Pure)

• Targeting pro-survival cell signaling pathways in multiple myeloma: personalized treatment for newly-diagnosed and relapsed-refractory patients

  Spaan, I., 28 Apr 2022, Utrecht University. 211 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Multiple Myeloma 100%
  • Signal Transduction 78%
  • Survival 56%
  • Bone Marrow 21%
  • Clonal Evolution 20%
  5 Downloads (Pure)

• The local innate immune response during severe respiratory syncytial virus infection

  Besteman, S., 23 Jun 2022, Utrecht University. 197 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Respiratory Syncytial Virus Infections 100%
  • Innate Immunity 71%
  • Neutrophils 60%
  • Infections 21%
  • Interferons 17%
  21 Downloads (Pure)

• Unravelling the complexity of psoriatic arthritis on a journey towards precision medicine

  Pouw, J., 1 Sept 2022, Utrecht: Utrecht University. 257 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Psoriatic Arthritis 100%
  • Precision Medicine 89%
  • Musculoskeletal Diseases 15%
  • Rheumatologists 14%
  • Antirheumatic Agents 14%
  21 Downloads (Pure)
• 2021

  Improvement of in vitro food allergy diagnostics by identifying unique antibody traits

  Ehlers, A., 18 Feb 2021, Utrecht University. 266 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Food Hypersensitivity 100%
  • Allergens 62%
  • Macadamia 56%
  • Arachis 49%
  • Antibodies 47%
  14 Downloads (Pure)

• Inhibitors and immune tolerance induction in hemophilia A, a balancing act

  Schep, S., 23 Dec 2021, Utrecht University. 222 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Immune Tolerance 100%
  • Hemophilia A 93%
  • Translational Medical Research 31%
  • Immune System Diseases 29%
  • Immunization 23%
  2 Downloads (Pure)

• Letting go of the dichotomy between psoriasis and psoriatic arthritis

  Leijten, E., 29 Jun 2021, Utrecht University. 213 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Psoriatic Arthritis 100%
  • Psoriasis 81%
  • Arthritis 29%
  • Sulfasalazine 21%
  • Thromboplastin 18%
  1 Downloads (Pure)

• Multi-omics: uncovering mechanisms of diseases and making medicine personalized

  Tao, W., 30 Mar 2021, Utrecht University. 226 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Precision Medicine 100%
  • Psoriasis 45%
  • Psoriatic Arthritis 37%
  • Systemic Scleroderma 35%
  • Ankylosing Spondylitis 35%
  25 Downloads (Pure)

• Patient profiling and prediction of response to immune-modulating treatment in moderate-to-severe atopic dermatitis

  Bakker, D., 28 Sept 2021, Utrecht University. 270 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Atopic Dermatitis 100%
  • dupilumab 59%
  • Conjunctivitis 31%
  • Biomarkers 16%
  • Therapeutics 15%
  14 Downloads (Pure)

• Respiratory syncytial virus infections on both ends of the age spectrum

  Korsten, K., 1 Apr 2021, Utrecht University. 200 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Respiratory Syncytial Virus Infections 100%
  • Respiratory Syncytial Viruses 90%
  • Child 27%
  • Independent Living 26%
  • Constitution and Bylaws 15%
  8 Downloads (Pure)

• Unveiling the two faces of immune dysregulation in Systemic Sclerosis: A multi-omics approach

  Servaas, N., 25 Nov 2021, Utrecht University. 240 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Systemic Scleroderma 100%
  • Autoimmune Diseases 30%
  • Immune System 27%
  • Psychological Imprinting 25%
  • Histone Code 20%
  4 Downloads (Pure)
• 2020

  A matter of life or death: targeting MCL-1 in multiple myeloma

  Slomp, A., 9 Sept 2020, Utrecht University. 194 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File
  19 Downloads (Pure)

• Exploring the role of monocyte dysregulation in the pathogenesis of Systemic Sclerosis

  van der Kroef, M., 27 Oct 2020, Utrecht: Utrecht University. 203 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Systemic Scleroderma 100%
  • Monocytes 72%
  • Angiopoietin-2 29%
  • Histone Code 20%
  • Fibrosis 20%
  8 Downloads (Pure)

• Hematopoietic Cell Transplantation in Inborn Errors of Metabolism: Hurdles to 'real' cure

  van den Broek, BTA., 16 Dec 2020, Utrecht University. 225 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Inborn Errors Metabolism 100%
  • Cell Transplantation 83%
  • Lysosomal Storage Diseases 13%
  • Disease Progression 11%
  • Quality of Life 9%
  18 Downloads (Pure)

• Immune monitoring in the context of hematopoietic cell transplantation in children

  Szanto, C., 15 Dec 2020, Utrecht University. 192 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Immunologic Monitoring 100%
  • Cell Transplantation 83%
  • Stem Cell Transplantation 81%
  • Child 33%
  • Immune System 20%
  3 Downloads (Pure)

• Impact of cytomegalovirus-infection on ageing of the immune system

  van den Berg, S., 18 Nov 2020, Utrecht University. 243 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Cytomegalovirus Infections 100%
  • Cytomegalovirus 90%
  • Immune System 71%
  • T-Lymphocytes 28%
  • Cell Count 14%
  12 Downloads (Pure)

• Macrophages and the Art of Controlling Pain in Inflammation and Osteoarthritis

  Raoof, R., 11 Dec 2020, Utrecht University. 201 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Art 100%
  • Osteoarthritis 76%
  • Macrophages 60%
  • Inflammation 50%
  • Pain 49%
  3 Downloads (Pure)

• SYNERKINE | IL4-10 fusion protein for the treatment of inflammatory diseases

  Steen-Louws, C., 4 Nov 2020, Utrecht University. 199 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Interleukin-4 100%
  • Proteins 39%
  • Cytokines 27%
  • Interleukin-10 23%
  • Therapeutics 17%
  1 Downloads (Pure)

• Tackling the Achilles heel of spondyloarthritis: Is it an autoinflammatory or autoimmune disease?

  van Kempen, T., 27 Oct 2020, Utrecht University. 129 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Psoriatic Arthritis 100%
  • Autoimmune Diseases 89%
  • Ankylosing Spondylitis 70%
  • invariant chain 61%
  • Synovial Fluid 47%
  9 Downloads (Pure)

• The role of hypoxia and metabolism in the pathogenesis of systemic sclerosis

  Ottria, A., 10 Jun 2020, Utrecht University. 227 p.

  Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

  Open Access

  File

  • Systemic Scleroderma 100%
  • Hypoxia 69%
  • endothelial PAS domain-containing protein 1 42%
  • Ligands 30%
  • Cytokines 27%
  2 Downloads (Pure)