Biomedical MR Imaging and Spectroscopy Group

Research output

Research output per year 1994 2015 2017 2018 2019 2020 2021 2024 2024

• 155 Article
• 17 Review article
• 10 Doctoral thesis 1 (Research UU / Graduation UU)
• 4 Meeting Abstract
• 9 More
  • 3 Chapter
  • 3 Comment/Letter to the editor
  • 2 Editorial
  • 1 Literature review

Research output per year

Research output per year

Search results

• 2024

  Ablation of oligodendrogenesis in adult mice alters brain microstructure and activity independently of behavioral deficits

  Kaller, M. S., Lazari, A., Feng, Y., van der Toorn, A., Rühling, S., Thomas, C. W., Shimizu, T., Bannerman, D., Vyazovskiy, V., Richardson, W. D., Sampaio-Baptista, C. & Johansen-Berg, H., Oct 2024, In: GLIA. 72, 10, p. 1728-1745 18 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

• ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes

  Vieira de Sá, R., Sudria-Lopez, E., Cañizares Luna, M., Harschnitz, O., van den Heuvel, D. M. A., Kling, S., Vonk, D., Westeneng, H-J., Karst, H., Bloemenkamp, L., Varderidou-Minasian, S., Schlegel, D. K., Mars, M., Broekhoven, M. H., van Kronenburg, N. C. H., Adolfs, Y., Vangoor, V. R., de Jongh, R., Ljubikj, T., Peeters, L., & 16 othersSeeler, S., Mocholi, E., Basak, O., Gordon, D., Giuliani, F., Verhoeff, T., Korsten, G., Calafat Pla, T., Venø, M. T., Kjems, J., Talbot, K., van Es, M. A., Veldink, J. H., van den Berg, L. H., Zelina, P. & Pasterkamp, R. J., 29 Aug 2024, In: Nature Communications. 15, 1, 7484.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

• CNS-associated macrophages contribute to intracerebral aneurysm pathophysiology

  Glavan, M., Jelic, A., Levard, D., Frösen, J., Keränen, S., Franx, B. A. A., Bras, A. R., Louet, E. R., Dénes, Á., Merlini, M., Vivien, D. & Rubio, M., 18 Mar 2024, In: Acta neuropathologica communications. 12, 1, 23 p., 43.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Aneurysm 100%
  • Macrophages 79%
  • Rupture 61%
  • Intracranial Aneurysm 22%
  • Clodronic Acid 14%

• Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats - Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements

  Mar 2024, In: Journal of Cerebral Blood Flow and Metabolism. 44, 3, p. 333-344 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Cerebral Blood Volume 100%
  • Middle Cerebral Artery Infarction 82%
  • Perfusion 45%
  • Hemodynamics 22%
  • Stroke 20%
  12 Downloads (Pure)

• Feasibility of an MR-based digital specimen for tongue cancer resection specimens: a novel approach for margin evaluation

  de Koning, K. J., Dankbaar, J. W., de Keizer, B., Willemsen, K., van der Toorn, A., Breimer, G. E., van Es, R. J. J., de Bree, R., Noorlag, R. & Philippens, M. E. P., 28 Mar 2024, In: Frontiers in oncology. 14, 11 p., 1342857.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Tongue Neoplasms 100%
  • Magnetic Resonance Spectroscopy 62%
  • Sensitivity and Specificity 34%
  • Hematoxylin 27%
  • Eosine Yellowish-(YS) 27%

• Feasibility of a randomized, sham-controlled pilot study for accelerated rTMS-treatment of the cerebellum plus physiotherapy in CANVAS patients

  Grobe-Einsler, M., Bork, F., Faikus, A., Neggers, S. F. W. & Kaut, O., 28 Jun 2024, In: NeuroRehabilitation. 54, 4, p. 691-698 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Transcranial Magnetic Stimulation 100%
  • Cerebellum 81%
  • Speech Therapy 58%
  • Ataxia 46%
  • Bilateral Vestibulopathy 36%

• Hyperperfusion profiles after recanalization differentially associate with outcomes in a rat ischemic stroke model

  Franx, B. A. A., van Tilborg, G. A. F., Taha, A., Bobi, J., van der Toorn, A., Van Heijningen, C. L., van Beusekom, H. M. M., Wu, O. & Dijkhuizen, R. M., Feb 2024, In: Journal of Cerebral Blood Flow and Metabolism. 44, 2, p. 209-223 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Regional Blood Flow 100%
  • Stroke 90%
  • Cerebrovascular Circulation 85%
  • Perfusion 66%
  • Cerebral Blood Volume 58%
  3 Downloads (Pure)

• Propofol anesthesia improves stroke outcomes over isoflurane anesthesia: a longitudinal multiparametric MRI study in a rodent model of transient middle cerebral artery occlusion

  Franx, B. A. A., van Tilborg, G. A. F., van der Toorn, A., van Heijningen, C. L., Dippel, D. W. J., van der Schaaf, I. C. & Dijkhuizen, R. M., Feb 2024, In: Frontiers in Neurology. 15, 10 p., 1332791.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Multiparametric Magnetic Resonance Imaging 100%
  • Isoflurane 82%
  • Middle Cerebral Artery Infarction 78%
  • Propofol 76%
  • Rodentia 59%
  1 Downloads (Pure)

• The association between air pollutant exposure and cerebral small vessel disease imaging markers with modifying effects of PRS-defined genetic susceptibility

  Sun, X., Ma, S., Guo, Y., Chen, C., Pan, L., Cui, Y., Chen, Z., Dijkhuizen, R. M., Zhou, Y., Boltze, J., Yu, Z. & Li, P., Aug 2024, In: Ecotoxicology and Environmental Safety. 281, 9 p., 116638.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Genetic Susceptibility 100%
  • Cerebral Small Vessel Diseases 87%
  • pollutant exposure 85%
  • Air Pollutant 80%
  • Air Pollutants 78%
• 2023

  A consensus protocol for functional connectivity analysis in the rat brain

  Apr 2023, In: Nature Neuroscience. 26, 4, p. 673-681 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Brain 100%
  • Neurosciences 72%
  • Neuroimaging 61%
  • Datasets 53%
  • Animal Models 49%

• Cerebral blood flow quantification with multi-delay arterial spin labeling in ischemic stroke and the association with early neurological outcome

  Luijten, S. P. R., Bos, D., van Doormaal, P. J., Goyal, M., Dijkhuizen, R. M., Dippel, D. W. J., Roozenbeek, B., van der Lugt, A. & Warnert, E. A. H., 2023, In: NeuroImage: Clinical. 37, p. 1-8 103340.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Cerebrovascular Circulation 100%
  • Stroke 70%
  • 1-dodecylpyridoxal 40%
  • Tissue Survival 33%
  • Thrombectomy 30%
  12 Downloads (Pure)

• Continuous Theta-Burst Stimulation of the Contralesional Primary Motor Cortex for Promotion of Upper Limb Recovery After Stroke: A Randomized Controlled Trial

  Vink, J. J. T., van Lieshout, E. C. C., Otte, W. M., van Eijk, R. P. A., Kouwenhoven, M., Neggers, S. F. W., van der Worp, H. B., Visser-Meily, J. M. A. & Dijkhuizen, R. M., 1 Aug 2023, In: Stroke. 54, 8, p. 1962-1971 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Motor Cortex 100%
  • Upper Extremity 90%
  • Stroke 67%
  • Randomized Controlled Trials 66%
  • Rehabilitation Centers 52%
  7 Downloads (Pure)

• In vivo imaging of cerebral glucose metabolism informs on subacute to chronic post-stroke tissue status – A pilot study combining PET and deuterium metabolic imaging

  Meerwaldt, A. E., Straathof, M., Oosterveld, W., van Heijningen, C. L., van Leent, M. M. T., Toner, Y. C., Munitz, J., Teunissen, A. J. P., Daemen, C. C., van der Toorn, A., van Vliet, G., van Tilborg, G. A. F., De Feyter, H. M., de Graaf, R. A., Hol, E. M., Mulder, W. J. M. & Dijkhuizen, R. M., May 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 5, p. 778-790 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Deuterium 100%
  • Positron-Emission Tomography 66%
  • Middle Cerebral Artery Infarction 59%
  • Stroke 49%
  • Glucose 45%
  4 Downloads (Pure)

• Multiparametric Immunoimaging Maps Inflammatory Signatures in Murine Myocardial Infarction Models

  Maier, A., Toner, Y. C., Munitz, J., Sullivan, N. A. T., Sakurai, K., Meerwaldt, A. E., Brechbühl, E. E. S., Prévot, G., van Elsas, Y., Maas, R. J. F., Ranzenigo, A., Soultanidis, G., Rashidian, M., Pérez-Medina, C., Heo, G. S., Gropler, R. J., Liu, Y., Reiner, T., Nahrendorf, M., Swirski, F. K., & 6 othersStrijkers, G. J., Teunissen, A. J. P., Calcagno, C., Fayad, Z. A., Mulder, W. J. M. & van Leent, M. M. T., Jul 2023, In: JACC: Basic to Translational Science. 8, 7, p. 801-816 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Myocardial Infarction 100%
  • Cardiovascular Diseases 99%
  • Apolipoproteins E 97%
  • Positron-Emission Tomography 85%
  • Inflammation 80%
  7 Downloads (Pure)

• Prevalence, risk factors and optimal way to determine overweight, obesity and morbid obesity, in the first Dutch cohort of 2,338 long-term survivors of childhood cancer: a DCCSS-LATER study

  Pluimakers, V. G., van Atteveld, J. E., de Winter, D. T. C., Bolier, M., Fiocco, M., Nievelstein, R. A. J., Janssens, G. O. R., Bresters, D., van der Heiden-van der Loo, M., de Vries, A. C. H., Louwerens, M., van der Pal, H. J., Pluijm, S. M. F., Ronckers, C. M., Versluijs, A. B., Kremer, L. C. M., Loonen, J. J., van Dulmen-den Broeder, E., Tissing, W. J. E., van Santen, H. M., & 2 othersvan den Heuvel-Eibrink, M. M. & Neggers, S. J. C. M. M., 8 Nov 2023, In: European Journal of Endocrinology. 189, 5, p. 495-507 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Morbid Obesity 100%
  • Cancer Survivors 95%
  • Overweight 76%
  • Survivors 76%
  • Obesity 60%
  5 Downloads (Pure)

• Thermosensitive Biodegradable Hydrogels for Local and Controlled Cerebral Delivery of Proteins: MRI-Based Monitoring of In Vitro and In Vivo Protein Release

  Yanev, P., van Tilborg, G. A. F., Boere, K. W. M., Stowe, A. M., van der Toorn, A., Viergever, M. A., Hennink, W. E., Vermonden, T. & Dijkhuizen, R. M., 13 Feb 2023, In: ACS Biomaterials Science and Engineering. 9, 2, p. 760-772 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Hydrogels 100%
  • Magnetic Resonance 80%
  • Magnetic resonance 80%
  • Proteins 70%
  • Hydrogel 61%
  9 Downloads (Pure)
• 2022

  Analysis of 567,758 randomized controlled trials published over 30 years reveals trends in phrases used to discuss results that do not reach statistical significance

  Otte, W. M., Vinkers, C. H., Habets, P. C., van IJzendoorn, D. G. P. & Tijdink, J. K., Feb 2022, In: PLoS Biology. 20, 2, e3001562.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • confidence interval 100%
  • Randomized Controlled Trials 94%
  • researchers 77%
  • Size Effect 52%
  • Time 50%
  7 Citations (Scopus)

  2 Downloads (Pure)

• Cumulative effects of antiseizure medication on intelligence in children with focal epilepsy

  Stevering, C. H., Lamberink, H. J., Woodfield, J., van Schooneveld, M., Otte, W. M., Chin, R. F. M., Bastin, M. E., Geleijns, K. & Braun, K. P. J., 1 Oct 2022, In: Epileptic disorders : international epilepsy journal with videotape. 24, 5, p. 877-888 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Partial Epilepsy 100%
  • Intelligence 90%
  • Child 36%
  • Epilepsy 35%
  • Seizures 24%

• Diet as connecting factor: Functional brain connectivity in relation to food intake and sucrose tasting, assessed with resting-state functional MRI in rats

  Roelofs, T. J. M., Straathof, M., van der Toorn, A., Otte, W. M., Adan, R. A. H. & Dijkhuizen, R. M., May 2022, In: Journal of Neuroscience Research. 100, 5, p. 1182-1190 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Sucrose 100%
  • Eating 77%
  • Diet 70%
  • Magnetic Resonance Imaging 67%
  • Brain 50%
  4 Downloads (Pure)

• Memantine treatment does not affect compulsive behavior or frontostriatal connectivity in an adolescent rat model for quinpirole-induced compulsive checking behavior

  Aug 2022, In: Psychopharmacology. 239, 8, p. 2457-2470 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Compulsive Behavior 100%
  • Quinpirole 99%
  • Memantine 95%
  • Injections 31%
  • Therapeutics 11%
  4 Downloads (Pure)

• Prolonged release of VEGF and Ang1 from intralesionally implanted hydrogel promotes perilesional vascularization and functional recovery after experimental ischemic stroke

  Yanev, P., van Tilborg, G. A. F., van der Toorn, A., Kong, X., Stowe, A. M. & Dijkhuizen, R. M., Jun 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 6, p. 1033-1048 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Angiopoietin-1 100%
  • Hydrogels 75%
  • Vascular Endothelial Growth Factor A 60%
  • Stroke 48%
  • Gels 46%

• VWF-targeted thrombolysis to overcome rh-tPA resistance in experimental murine ischemic stroke models

  van Moorsel, M. V. A., de Maat, S., Vercruysse, K., van Leeuwen, E. M., Jacqmarcq, C., Bonnard, T., Vivien, D., van der Worp, H. B., Dijkhuizen, R. M. & Maas, C., 29 Dec 2022, In: Blood. 140, 26, p. 2844-2848 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Fibrinolytic Agent 100%
  • von Willebrand Factor 66%
  • Tissue Plasminogen Activator 64%
  • Thrombosis 46%
  • Fibrinolytic Agents 44%
• 2021

  Activation response and functional connectivity change in rat cortex after bilateral transcranial direct current stimulation—An exploratory study

  Boonzaier, J., Straathof, M., Ardesch, D. J., van der Toorn, A., van Vliet, G., van Heijningen, C. L., Otte, W. M. & Dijkhuizen, R. M., May 2021, In: Journal of Neuroscience Research. 99, 5, p. 1377-1389 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Transcranial Direct Current Stimulation 100%
  • Magnetic Resonance Imaging 18%
  • Sensorimotor Cortex 17%
  • Magnetic Resonance Angiography 16%
  • Brain 6%
  4 Downloads (Pure)

• Altered effective connectivity within an oculomotor control network in unaffected relatives of individuals with schizophrenia

  Lehet, M., Tso, I. F., Park, S., Neggers, S. F. W., Thompson, I. A., Kahn, R. S. & Thakkar, K. N., Sept 2021, In: Brain sciences. 11, 9, 1228.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Schizophrenia 100%
  • Psychological Inhibition 60%
  • Efficiency 53%
  • Saccades 28%
  • REM Sleep 27%
  8 Downloads (Pure)

• Bayesian model-averaged meta-analysis in medicine

  Bartoš, F., Gronau, Q. F., Timmers, B., Otte, W. M., Ly, A. & Wagenmakers, E. J., 30 Dec 2021, In: Statistics in Medicine. 40, 30, p. 6743-6761 19 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Bayesian Model 100%
  • Medicine 96%
  • Prior distribution 88%
  • Meta-Analysis 66%
  • Databases 53%
  7 Citations (Scopus)

• Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury

  Ustaoglu, S. G., Ali, M. H. M., Rakib, F., Blezer, E. L. A., Van Heijningen, C. L., Dijkhuizen, R. M. & Severcan, F., 14 Jun 2021, In: Scientific Reports. 11, 1, 13 p., 12468.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Brain Concussion 100%
  • Traumatic Brain Injury 77%
  • Lipids 22%
  • Brain 16%
  • Secondary Protein Structure 16%
  24 Downloads (Pure)

• Brain Tissue Conductivity Measurements with MR-Electrical Properties Tomography: An In Vivo Study

  Mandija, S., Petrov, P. I., Vink, J. J. T., Neggers, S. F. W. & van den Berg, C. A. T., Jan 2021, In: Brain Topography. 34, 1, p. 56-63 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Tomography 100%
  • Brain 71%
  • Healthy Volunteers 48%
  • Benchmarking 39%
  • Granulocyte-Macrophage Colony-Stimulating Factor 38%
  14 Downloads (Pure)

• Epidemiology of Epilepsy in Nigeria: A Community-Based Study From 3 Sites

  Watila, M. M., Balarabe, S. A., Komolafe, M. A., Igwe, S. C., Fawale, M. B., Otte, W. M., Van Diessen, E., Okunoye, O., Mshelia, A. A., Abdullahi, I., Musa, J., Hedima, E. W., Nyandaiti, Y. W., Singh, G., Winkler, A. S. & Sander, J. W., 17 Aug 2021, In: Neurology. 97, 7, p. E728-E738

  Research output: Contribution to journal › Article › Academic › peer-review

  • Nigeria 100%
  • Epilepsy 80%
  • Epidemiology 74%
  • Perinatal Care 43%
  • Febrile Seizures 40%
  4 Citations (Scopus)

• Good taste or gut feeling? A new method in rats shows oro-sensory stimulation and gastric distention generate distinct and overlapping brain activation patterns

  Roelofs, T. J. M., Luijendijk, M. C. M., van der Toorn, A., Camps, G., Smeets, P. A. M., Dijkhuizen, R. M. & Adan, R. A. H., Jul 2021, In: International Journal of Eating Disorders. 54, 7, p. 1116-1126 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Satiation 100%
  • Emotions 92%
  • Stomach 83%
  • Brain 57%
  • Sucrose 45%
  5 Downloads (Pure)

• Imaging Markers for the Characterization of Gray and White Matter Changes from Acute to Chronic Stages after Experimental Traumatic Brain Injury

  Sinke, M. R. T., Otte, W. M., Meerwaldt, A. E., Franx, B. A. A., Ali, M. H. M., Rakib, F., van der Toorn, A., van Heijningen, C. L., Smeele, C., Ahmed, T., Blezer, E. L. A. & Dijkhuizen, R. M., 15 Jun 2021, In: Journal of Neurotrauma. 38, 12, p. 1642-1653 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Gray Matter 100%
  • Traumatic Brain Injury 96%
  • White Matter 89%
  • Brain Concussion 46%
  • Diffusion Magnetic Resonance Imaging 28%

• Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity

  Vaes, J. E. G., van Kammen, C. M., Trayford, C., van der Toorn, A., Ruhwedel, T., Benders, M. J. N. L., Dijkhuizen, R. M., Möbius, W., van Rijt, S. H. & Nijboer, C. H., Mar 2021, In: GLIA. 69, 3, p. 655-680 26 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Brain Diseases 100%
  • Cell- and Tissue-Based Therapy 99%
  • Mesenchymal Stem Cells 94%
  • Oligodendroglia 86%
  • White Matter 83%
  6 Downloads (Pure)

• Molecular Magnetic Resonance Imaging of Vascular Inflammation After Recanalization in a Rat Ischemic Stroke Model

  Franx, B. A. A., Van der Toorn, A., Van Heijningen, C., Vivien, D., Bonnard, T. & Dijkhuizen, R. M., Dec 2021, In: Stroke. 52, 12, p. e788-e791

  Research output: Contribution to journal › Article › Academic › peer-review

  • Vascular Cell Adhesion Molecule-1 100%
  • Stroke 79%
  • Magnetic Resonance Imaging 76%
  • Inflammation 68%
  • Blood Vessels 68%

• New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases

  Boltze, J., Aronowski, J. A., Badaut, J., Buckwalter, M. S., Caleo, M., Chopp, M., Dave, K. R., Didwischus, N., Dijkhuizen, R. M., Doeppner, T. R., Dreier, J. P., Fouad, K., Gelderblom, M., Gertz, K., Golubczyk, D., Gregson, B. A., Hamel, E., Hanley, D. F., Härtig, W., Hummel, F. C., & 36 othersIkhsan, M., Janowski, M., Jolkkonen, J., Karuppagounder, S. S., Keep, R. F., Koerte, I. K., Kokaia, Z., Li, P., Liu, F., Lizasoain, I., Ludewig, P., Metz, G. A. S., Montagne, A., Obenaus, A., Palumbo, A., Pearl, M., Perez-Pinzon, M., Planas, A. M., Plesnila, N., Raval, A. P., Rueger, M. A., Sansing, L. H., Sohrabji, F., Stagg, C. J., Stetler, R. A., Stowe, A. M., Sun, D., Taguchi, A., Tanter, M., Vay, S. U., Vemuganti, R., Vivien, D., Walczak, P., Wang, J., Xiong, Y. & Zille, M., 28 Jan 2021, In: Frontiers in Aging Neuroscience. 13, 15 p., 623751.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Cerebrovascular Disorders 100%
  • Stroke 52%
  • Traumatic Cerebral Hemorrhage 35%
  • Traumatic Brain Hemorrhage 34%
  • Neurological Rehabilitation 25%
  10 Downloads (Pure)

• Optimization of whole-brain rabies virus tracing technology for small cell populations

  Roelofs, T. J. M., Menting-Henry, S., Gol, L. M., Speel, A. M., Wielenga, V. H., Garner, K. M., Luijendijk, M. C. M., Hennrich, A. A., Conzelmann, K. K. & Adan, R. A. H., 17 May 2021, In: Scientific Reports. 11, 1, 10400.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Rabies virus 100%
  • Lateral Hypothalamic Area 94%
  • Virus Receptors 73%
  • Oncogenic Viruses 68%
  • Technology 49%
  7 Downloads (Pure)

• Remote Corticospinal Tract Degeneration After Cortical Stroke in Rats May Not Preclude Spontaneous Sensorimotor Recovery

  Sinke, M. R. T., van Tilborg, G. A. F., Meerwaldt, A. E., van Heijningen, C. L., van der Toorn, A., Straathof, M., Rakib, F., Ali, M. H. M., Al-Saad, K., Otte, W. M. & Dijkhuizen, R. M., 1 Nov 2021, In: Neurorehabilitation and Neural Repair. 35, 11, p. 1010-1019 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Pyramidal Tracts 100%
  • Stroke 55%
  • Forelimb 24%
  • Sensorimotor Cortex 12%
  • Diffusion Magnetic Resonance Imaging 11%
  4 Downloads (Pure)

• Translational Value of Skilled Reaching Assessment in Clinical and Preclinical Studies on Motor Recovery After Stroke

  van Lieshout, E. C. C., Boonzaier, J., Pel, A. J., van Heijningen, C. L., Vink, J. J., Visser-Meily, J. M. A., van Tilborg, G. A. F. & Dijkhuizen, R. M., May 2021, In: Neurorehabilitation and Neural Repair. 35, 5, p. 457-467 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Clinical Studies 100%
  • Stroke 98%
  • Upper Extremity 65%
  • Health Services Research 54%
  • Health Care Outcome Assessment 47%
  4 Downloads (Pure)
• 2020

  Active Recharge Burst and Tonic Spinal Cord Stimulation Engage Different Supraspinal Mechanisms: A Functional Magnetic Resonance Imaging Study in Peripherally Injured Chronic Neuropathic Rats

  Meuwissen, K. P. V., van der Toorn, A., Gu, J. W., Zhang, T. C., Dijkhuizen, R. M. & Joosten, E. A. J., 1 Jun 2020, In: Pain Practice. 20, 5, p. 510-521 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Spinal Cord Stimulation 100%
  • Magnetic Resonance Imaging 49%
  • Pain 17%
  • Raphe Nuclei 8%
  • Isoflurane 7%
  1 Citation (Scopus)

• Comparison of self-reported vs observational clinical measures of improvement in upper limb capacity in patients after stroke

  Van Lieshout, E. C. C., Visser-Meily, J. M. A., Nijland, R. H. M., Dijkhuizen, R. M. & Kwakkel, G., 22 Apr 2020, In: Journal of Rehabilitation Medicine. 52, 4, p. jrm00051 7 p., jrm00051.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Upper Extremity 100%
  • Stroke 74%
  • Hand 27%
  • Arm 21%
  • Health Services Research 13%
  9 Downloads (Pure)

• Design and Evaluation of a Rodent-Specific Transcranial Magnetic Stimulation Coil: An In Silico and In Vivo Validation Study

  Boonzaier, J., Petrov, P. I., Otte, W. M., Smirnov, N., Neggers, S. F. W. & Dijkhuizen, R. M., 1 Apr 2020, In: Neuromodulation. 23, 3, p. 324-334 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Transcranial Magnetic Stimulation 100%
  • Validation Studies 98%
  • Computer Simulation 83%
  • Rodentia 73%
  • Motor Evoked Potentials 18%
  5 Downloads (Pure)

• Distinct structure-function relationships across cortical regions and connectivity scales in the rat brain

  Straathof, M., Sinke, M. R. T., Roelofs, T. J. M., Blezer, E. L. A., Sarabdjitsingh, R. A., van der Toorn, A., Schmitt, O., Otte, W. M. & Dijkhuizen, R. M., 1 Dec 2020, In: Scientific Reports. 10, 1, 14 p., 56.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Brain 100%
  • Brain Diseases 64%
  • Magnetic Resonance Imaging 45%
  3 Downloads (Pure)

• Does upper limb strength play a prominent role in health-related quality of life in stroke patients discharged from inpatient rehabilitation?

  Lieshout, E. C. C. V., van de Port, I. G., Dijkhuizen, R. M. & Visser-Meily, J. M. A., 2 Oct 2020, In: Topics in Stroke Rehabilitation. 27, 7, p. 525-533 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • stroke 100%
  • Upper Extremity 79%
  • rehabilitation 71%
  • Inpatients 69%
  • quality of life 69%
  1 Citation (Scopus)

  6 Downloads (Pure)

• Exploring the experiences of stroke patients treated with transcranial magnetic stimulation for upper limb recovery: A qualitative study

  Van Lieshout, E. C. C., Jacobs, L. D., Pelsma, M., Dijkhuizen, R. M. & Visser-Meily, J. M. A., 6 Oct 2020, In: BMC Neurology. 20, 1, p. 1-13 365.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Transcranial Magnetic Stimulation 100%
  • Upper Extremity 81%
  • Stroke 60%
  • Motivation 26%
  • Altruism 15%
  3 Downloads (Pure)

• Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging

  Senders, M. L., Meerwaldt, A. E., van Leent, M. M. T., Sanchez-Gaytan, B. L., van de Voort, J. C., Toner, Y. C., Maier, A., Klein, E. D., Sullivan, N. A. T., Sofias, A. M., Groenen, H., Faries, C., Oosterwijk, R. S., van Leeuwen, E. M., Fay, F., Chepurko, E., Reiner, T., Duivenvoorden, R., Zangi, L., Dijkhuizen, R. M., & 9 othersHak, S., Swirski, F. K., Nahrendorf, M., Pérez-Medina, C., Teunissen, A. J. P., Fayad, Z. A., Calcagno, C., Strijkers, G. J. & Mulder, W. J. M., 1 May 2020, In: Nature nanotechnology. 15, 5, p. 398-405 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • heart diseases 100%
  • hardware description languages 60%
  • Imaging techniques 49%
  • Positron 37%
  • cells 34%
  2 Citations (Scopus)

• Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study

  Lamberink, H. J., Otte, W. M., Blümcke, I. & Braun, K. PJ., Sept 2020, In: The Lancet Neurology. 19, 9, p. 748-757 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Anticonvulsants 100%
  • Multicenter Studies 92%
  • Epilepsy 89%
  • Seizures 82%
  • Cohort Studies 72%

• Structural and functional MRI of altered brain development in a novel adolescent rat model of quinpirole-induced compulsive checking behavior

  1 Apr 2020, In: European Neuropsychopharmacology. 33, p. 58-70 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Compulsive Behavior 100%
  • Quinpirole 99%
  • Obsessive-Compulsive Disorder 47%
  • Magnetic Resonance Imaging 46%
  • Brain 34%

• Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

  Priem, B., van Leent, M. M. T., Teunissen, A. J. P., Sofias, A. M., Mourits, V. P., Willemsen, L., Klein, E. D., Oosterwijk, R. S., Meerwaldt, A. E., Munitz, J., Prévot, G., Vera Verschuur, A., Nauta, S. A., van Leeuwen, E. M., Fisher, E. L., de Jong, K. A. M., Zhao, Y., Toner, Y. C., Soultanidis, G., Calcagno, C., & 25 othersBomans, P. H. H., Friedrich, H., Sommerdijk, N., Reiner, T., Duivenvoorden, R., Zupančič, E., Di Martino, J. S., Kluza, E., Rashidian, M., Ploegh, H. L., Dijkhuizen, R. M., Hak, S., Pérez-Medina, C., Bravo-Cordero, J. J., de Winther, M. P. J., Joosten, L. A. B., van Elsas, A., Fayad, Z. A., Rialdi, A., Torre, D., Guccione, E., Ochando, J., Netea, M. G., Griffioen, A. W. & Mulder, W. J. M., 29 Oct 2020, In: Cell. 183, 3, p. 786-801.e19

  Research output: Contribution to journal › Article › Academic › peer-review

  • Refractory 100%
  • Safety 82%
  • Immunity 78%
  • Bone Marrow 52%
  • Drug 50%
  2 Citations (Scopus)

• Ultrahigh-resolution MRI reveals structural brain differences in serotonin transporter knockout rats after sucrose and cocaine self-administration

  Karel, P., Van der Toorn, A., Vanderschuren, L., Guo, C., Sadighi Alvandi, M., Reneman, L., Dijkhuizen, R., Verheij, M. M. M. & Homberg, J. R., 1 Jan 2020, In: Addiction Biology. 25, 1, p. e12722 e12722.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Serotonin Plasma Membrane Transport Proteins 100%
  • Self Administration 95%
  • Cocaine 80%
  • Sucrose 78%
  • Cocaine-Related Disorders 76%
  1 Citation (Scopus)

  1 Downloads (Pure)

• Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies

  Slooter, A. J. C., Otte, W. M., Devlin, J. W., Arora, R. C., Bleck, T. P., Claassen, J., Duprey, M. S., Ely, E. W., Kaplan, P. W., Latronico, N., Morandi, A., Neufeld, K. J., Sharshar, T., MacLullich, A. M. J. & Stevens, R. D., May 2020, In: Intensive Care Medicine. 46, 5, p. 1020-1022 3 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
• 2019

  Branching Pattern of the Cerebral Arterial Tree

  Helthuis, J. H. G., van Doormaal, T. P. C., Hillen, B., Bleys, R. L. A. W., Harteveld, A. A., Hendrikse, J., van der Toorn, A., Brozici, M., Zwanenburg, J. J. M. & van der Zwan, A., 1 Aug 2019, In: Anatomical Record - Advances in Integrative Anatomy and Evolutionary Biology. 302, 8, p. 1434-1446 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Corrosion 100%
  • bifurcation 88%
  • branching 77%
  • corrosion 52%
  • Cerebral Arteries 50%
  1 Downloads (Pure)

• Circle of Willis variations in migraine patients with ischemic stroke

  Hamming, A. M., van Walderveen, M. A. A., Mulder, I. A., van der Schaaf, I. C., Kappelle, L. J., Velthuis, B. K., Ferrari, M. D., Terwindt, G. M., Visser, M. C., Schonewille, W., Algra, A., Wermer, M. J. H., Majoie, C. B., Roos, Y. B., Duijm, L. E., Keizer, K., van der Lugt, A., Dippel, D. W., Droogh-de Greeve, K. E., Bienfait, H. P., & 23 othersLycklama a Nijeholt, G. J., Boiten, J., Duyndam, D., Kwa, V. . I., Meijer, F. J., van Dijk, E. J., Kesselring, F. O., Hofmeijer, J., Vos, J. A., van Rooij, W. J., de Kort, P. L., Pleiter, C. C., Bakker, S. L., Bot, J., Velthuis, B. K., Dankbaar, J. W., Mali, W. P., van Seeters, T., Horsch, A. D., Niesten, J. M., Biessels, G. J., Luitse, M. J. & van der Graaf, Y., Mar 2019, In: Brain and Behavior. 9, 3, p. e01223 e01223.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Circle of Willis 100%
  • Migraine Disorders 71%
  • Stroke 48%
  • Arteries 15%
  • Migraine without Aura 13%