Computational Approaches to Facilitate Epitope-Based HLA Matching in Solid Organ Transplant

Activity: Talk or presentationInvited talkAcademic


Although HLA genotyping methodologies have improved, rapid availability of reliable high-resolution typing data remains challenging. Participants will learn about a computational method to perform epitope-based matching using serologic split-level HLA typing to predict high-resolution genotypes based on HLA haplotype frequency tables. This computational approach may be a powerful tool to estimate either PIRCHE-II (Predicted Indirectly ReCognizable HLA Epitopes) or HLA Matchmaker eplet values when high-resolution data is not available
Period17 Nov 2019
Event titleASHI 2019 Audio Lectures: Topics in Histocompatibility and Transplantation
Event typeSeminar
LocationWashington, United States, District of ColumbiaShow on map
Degree of RecognitionInternational